Joint Bone Spine最新文献

Severity and mortality of inflammatory rheumatic diseases: evolution of approaches. 炎症性风湿病的严重程度和死亡率：方法的演变。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-27 DOI: 10.1016/j.jbspin.2025.105931

Chloé Bernardy, Mickaël Dalecky, Sarah Guillaud-Rollin, Tiphaine Dujardin, Romain Gastaldi, Athan Baillet

引用次数: 0

A response to Annweiler and al. about "Comments on: Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO". 对Annweiler等人关于“评论：骨质疏松症患者或有骨质疏松症风险的患者每日或间歇性补充维生素D: GRIO的立场声明”的回应。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-27 DOI: 10.1016/j.jbspin.2025.105925

Marie-Eva Pickering, Jean-Claude Souberbielle, Bernard Cortet

引用次数: 0

Early Peripheral Psoriatic Arthritis: Baseline Features of the First 186 Patients in the French Nationwide APACHE Cohort. 早期周围性银屑病关节炎：法国全国APACHE队列中首批186名患者的基线特征

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-27 DOI: 10.1016/j.jbspin.2025.105930

Pascal Claudepierre, Cecile Gaujoux-Viala, Arnaud Constantin, Francis Berenbaum, Bernard Combe, Valerie Devauchelle, Philippe Goupille, Pascal Richette, Daniel Wendling, Gael Mouterde, Tristan Pascart, Benedicte Razat, Etienne Audureau, Sandrine Jousse-Joulin, Laure Gossec

{"title":"Early Peripheral Psoriatic Arthritis: Baseline Features of the First 186 Patients in the French Nationwide APACHE Cohort.","authors":"Pascal Claudepierre, Cecile Gaujoux-Viala, Arnaud Constantin, Francis Berenbaum, Bernard Combe, Valerie Devauchelle, Philippe Goupille, Pascal Richette, Daniel Wendling, Gael Mouterde, Tristan Pascart, Benedicte Razat, Etienne Audureau, Sandrine Jousse-Joulin, Laure Gossec","doi":"10.1016/j.jbspin.2025.105930","DOIUrl":"https://doi.org/10.1016/j.jbspin.2025.105930","url":null,"abstract":"Objectives: To describe the design and methodology of APACHE, a cohort of patients with early peripheral psoriatic arthritis (pPsA), and to assess the main baseline clinical characteristics of the first included patients.Methods: APACHE is an ongoing prospective multicentre national cohort (NCT03768271) with a planned follow-up of 10 years. Included patients have recent-onset (<12 months) peripheral arthritis, a personal and/or family history of psoriasis, pPsA diagnosed by a rheumatologist, and no history of targeted disease-modifying antirheumatic drug therapy. At inclusion, demographic data, disease activity, comorbidities, and imaging results (not reported here) are collected. A descriptive analysis of these data was performed.Results: The 186 study patients had a mean age of 44±11 years and mean arthritis duration of 6±4 months; 84 (45%) were women; 169 (91%) had a history of psoriasis (mean duration, 14 years) and 71 (38%) were receiving methotrexate. Disease activity was moderate with a mean DAPSA score of 19±14 and mean swollen and tender joint counts of 2.1±3.2 and 6.0±8.0, respectively. The initially involved joints were mainly the hands (40%) and knees (28%). Entheseal pain (39%) was more prevalent than dactylitis (27%). Comorbidities were common, with obesity in 27% and at least one cardiovascular risk factor or disease in 49% of patients.Conclusion: Patients with early peripheral PsA had moderate disease activity, a predominant oligoarticular profile, and a high prevalence of entheseal pain.","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":" ","pages":"105930"},"PeriodicalIF":3.8,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144181782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Metatarsal Stress Fractures Mimicking a Flare in an Obese Patient with Rheumatoid Arthritis. 肥胖类风湿性关节炎患者双侧跖骨应力性骨折模拟耀斑。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-26 DOI: 10.1016/j.jbspin.2025.105926

Nur Kakilli, Doğukan Erkal, Mert Çiftdemir, Nurettin Taştekin

引用次数: 0

Correlation of Naples prognostic score with the risk of all-cause and cardiovascular mortality in individuals with rheumatoid arthritis: a cross-sectional analysis of the NHANES 2001-2018. 那不勒斯预后评分与类风湿关节炎患者全因和心血管死亡风险的相关性：NHANES 2001-2018的横断面分析

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-26 DOI: 10.1016/j.jbspin.2025.105928

Feiyue Zhou, Yuhan Xie, Yiran Zhang, Ping Jiang

{"title":"Correlation of Naples prognostic score with the risk of all-cause and cardiovascular mortality in individuals with rheumatoid arthritis: a cross-sectional analysis of the NHANES 2001-2018.","authors":"Feiyue Zhou, Yuhan Xie, Yiran Zhang, Ping Jiang","doi":"10.1016/j.jbspin.2025.105928","DOIUrl":"https://doi.org/10.1016/j.jbspin.2025.105928","url":null,"abstract":"Objectives: This study seeks to assess how the Naples Prognostic Score (NPS) correlates with mortality in individuals with RA.Methods: This study assessed the National Health and Nutrition Examination Survey (NHANES) database spanning from 2001 to 2018. NPS was computed utilizing serum albumin (SA), total cholesterol (TC), neutrophil to lymphocyte ratio (NLR), and lymphocyte to monocyte ratio (LMR). A self-administered questionnaire was utilized to gather data from individuals with RA, and the national death index was adopted to determine death rates. Weighted multivariate Cox regression evaluation and Kaplan-Meier survival curve assessment were carried out to explore the correlation of NPS with RA mortality risk, and subgroup analysis and sensitivity analysis were performed to investigate the robustness of the correlation.Results: Altogether 1,683 individuals with RA were enrolled in this research. In the Kaplan-Meier analysis, notable survival discrepancies were observed among various groups in all-cause and cardiovascular (CV) mortality events (P<0.001). Following adjustment for all confounders, Group 3 (NPS=3-4) exhibited a markedly heightened likelihood of all-cause mortality by 2.04 times (hazard ratio (HR)=2.04, 95% confidence interval (CI): 1.21-3.05, P<0.01) and CV mortality by 3.59 times (HR=3.59, 95%CI: 1.24-10.4, P<0.05) in comparison to Group 1 (NPS=0). Subgroup analysis and sensitivity analysis indicated that the results were robust.Conclusion: In the US population, NPS shows a significantly positive correlation with the likelihood of all-cause and CV mortality in individuals with RA. The integration of the NPS into clinical decision-making can offer a more dependable evaluation of the prognosis of individuals with RA.","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":" ","pages":"105928"},"PeriodicalIF":3.8,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Balancing efficacy and adherence: Importance of patient-centered approach to vitamin D supplementation. Comment on: "Pickering ME, Souberbielle JC, Boutten A, et al. Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO" by Pickering et al. Joint Bone Spine 2025;92:105858. 平衡疗效和依从性：以患者为中心的维生素D补充方法的重要性。评论：“Pickering ME, Souberbielle JC, Boutten A，等。骨质疏松症患者或有骨质疏松症风险的患者每日或间歇性补充维生素D: Pickering等人的gro立场声明。关节骨脊柱2025；92:105858。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-26 DOI: 10.1016/j.jbspin.2025.105927

Cédric Annweiler, Mathieu Corvaisier

引用次数: 0

Global, regional, and national burden of gout in people aged 15-39 years from 1990 to 2021: trends, cross-country inequalities and forecast to 2035. 1990年至2021年全球、区域和国家15-39岁人群痛风负担：趋势、跨国不平等和2035年预测

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-26 DOI: 10.1016/j.jbspin.2025.105929

Yinglun Zhang, Zhibin Jin, Jing Yao, Dandan Wang, Yu Yunxian, Weijing Zhang

{"title":"Global, regional, and national burden of gout in people aged 15-39 years from 1990 to 2021: trends, cross-country inequalities and forecast to 2035.","authors":"Yinglun Zhang, Zhibin Jin, Jing Yao, Dandan Wang, Yu Yunxian, Weijing Zhang","doi":"10.1016/j.jbspin.2025.105929","DOIUrl":"https://doi.org/10.1016/j.jbspin.2025.105929","url":null,"abstract":"Objectives: To evaluate the trends and cross-country inequalities of gout burden in people aged 15-39 years from 1990 to 2021, with projections to 2035.Methods: The study employed estimates from Global Burden of Diseases (GBD) 2021 to assess prevalence, incidence, and years lived with disability (YLDs) of gout across global, demographic, GBD regional, national, sociodemographic index (SDI) regional, and risk factor levels. Temporal trends in the age-standardized rates (ASRs) of prevalence, incidence and YLDs were assessed by Joinpoint regression, while associations between SDI and ASRs were examined through Spearman correlation. Health inequalities were measured using the slope index of inequality and the concentration index. Future trends were forecast by a Bayesian age-period-cohort model.Results: The burden of gout increased in global, demographic, GBD regional, and SDI level from 1990 to 2021. Males, the 35-39 years subgroup, and High-SDI regions experienced the highest burden. High-income North America owned the highest ASRs while East Asia reported the largest numbers. A moderate positive correlation was observed between gout burden and SDI for nations. Both absolute and relative inequalities increased. Males had higher YLDs due to high body mass index (BMI), females due to kidney dysfunction. Although ASRs were predicted to decrease from 2020 to 2035, numbers were predicted to rise.Conclusions: The gout burden gout in people aged 15-39 years increased with notable inequalities. Despite projected ASRs decreases, overall numbers were likely to increase, highlighting the urgent need for targeted interventions and public health strategies.","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":" ","pages":"105929"},"PeriodicalIF":3.8,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advanced Combination Therapy in Inflammatory Bowel Disease. 炎性肠病的高级联合治疗。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-23 DOI: 10.1016/j.jbspin.2025.105922

Caroline Morizot, Léa Sequier, Jean-Yves Jouzeau, David Moulin, Patrick Netter, Bénédicte Caron, Sailish Honap, Damien Lœuille, Laurent Peyrin-Biroulet

{"title":"Advanced Combination Therapy in Inflammatory Bowel Disease.","authors":"Caroline Morizot, Léa Sequier, Jean-Yves Jouzeau, David Moulin, Patrick Netter, Bénédicte Caron, Sailish Honap, Damien Lœuille, Laurent Peyrin-Biroulet","doi":"10.1016/j.jbspin.2025.105922","DOIUrl":"https://doi.org/10.1016/j.jbspin.2025.105922","url":null,"abstract":"Background: The advent of advanced therapies in the recent years have improved outcomes for inflammatory bowel disease patients, but a significant subset of patients remains refractory to monotherapy. Advanced Combination Therapy, involving two biologic agents or a biologic combined with a small molecule drug, is emerging as a potential strategy to improve clinical remission and address extra-intestinal manifestations.Methods: This narrative review summarize current evidence on advanced combination therapy for inflammatory bowel disease, including mechanisms of action, clinical efficacy, safety considerations, and future perspectives. Key clinical trials and real-world studies were analyzed to assess advanced combination therapy outcomes.Results: Preliminary data indicate that advanced combination therapy enhances response rates in patients who fail monotherapy and appears to be a new therapeutic option in patients with refractory disease or extra-intestinal manifestations. However, long-term safety concerns remain, and few clinicals trials have investigated advanced combination therapy, and standardized guidelines regarding its use in clinical practice are lacking.Conclusions: Advanced combination therapy represents a promising yet evolving approach in inflammatory bowel disease management. Future research should focus on optimizing combination strategies, identifying patient subgroups most likely to benefit, and establishing safety profiles through large-scale controlled trials. The integration of precision medicine approaches, including biomarker-driven treatment selection, will be crucial in maximizing the efficacy of advanced combination therapy in clinical practice.","PeriodicalId":54902,"journal":{"name":"Joint Bone Spine","volume":" ","pages":"105922"},"PeriodicalIF":3.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Future options in the treatment of Giant Cell Arteritis. 巨细胞动脉炎治疗的未来选择。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-20 DOI: 10.1016/j.jbspin.2025.105924

Mathilde Plantié, Guillermo Carvajal Alegria

引用次数: 0

Locked Jaw in a Connective Tissue Disease: Trismus as a Rare Manifestation of Scleromyositis. 结缔组织疾病中的锁颌：硬化症的罕见表现为牙关紧闭。

IF 3.8 3区医学

Joint Bone Spine Pub Date : 2025-05-20 DOI: 10.1016/j.jbspin.2025.105921

Maurane Lepage, Laure Gallay, Thomas El Jammal, Gaëlle Richard Colmant, Maxime Fauter, Pascal Sève

引用次数: 0