{"title":"Contralateral neck metastasis in lateralized cT3/4N0 oral squamous cell carcinoma.","authors":"Qigen Fang, Junhui Yuan, Tao Huang","doi":"10.1016/j.jcms.2024.12.008","DOIUrl":"https://doi.org/10.1016/j.jcms.2024.12.008","url":null,"abstract":"<p><p>Our goal was to investigate the pattern of contralateral lymphatic drainage (CLD) and contralateral neck failure (CNF) in cT3/4N0 oral cancer patients subjected to lymphoscintigraphy guided elective neck dissection (LSG-END) versus END. Patients were retrospectively enrolled and divided into two groups based on neck management. Pattern of CLD in LSG-END cohort was descriptively presented. Impact of LSG-END vs. END on CNF and overall survival was analyzed using Cox model. In total, 450 patients were included. In the LSG-END group, 54 patients exhibited CLD, resulting in an incidence of 23.5% and independently predicted by primary site, differentiation, tumor stage, and lymphovascular invasion. Contralateral levels I and II were the most involved site, and significantly influenced by primary site. In Cox model, patients treated with END had approximately double the risk of contralateral recurrence compared to those managed with LSG-END. Patients undergoing treatment with either END or LSG-END exhibited comparable OS rates. Among patients with cT3/4N0 oral cancer, CLD was observed in approximately one-quarter of the cohort. Although no additional overall survival advantage was identified, LSG-END proved to be more effective in controlling CNF compared to conventional END.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huanze Deng, Jing Xu, Jia Nie, Hongru Wang, Yinxia Sun, Yanfeng Li
{"title":"Application of task-autonomous dental robot for lateral window preparation in the maxillary sinus.","authors":"Huanze Deng, Jing Xu, Jia Nie, Hongru Wang, Yinxia Sun, Yanfeng Li","doi":"10.1016/j.jcms.2024.11.005","DOIUrl":"https://doi.org/10.1016/j.jcms.2024.11.005","url":null,"abstract":"<p><p>The study aimed to investigate the feasibility and accuracy of task-autonomous dental robots for lateral window preparation in the maxillary sinus, as well as to propose 3 indexes for assessing the accuracy of lateral window preparation. Twenty 1:1 resin maxilla models were fabricated, all of which underwent preoperative CBCT and utilized the data to design 40 lateral windows. A task-autonomous dental robot was used to autonomously perform the preparation of 20 lateral windows according to the design under supervision, while another 20 lateral windows were prepared with freehand as control. Morphology of the postoperative lateral windows was obtained using oral scans for accuracy analysis. Three indexes (center displacement, area overlap ratio, and area difference) were used to evaluate the accuracy of lateral window preparation in 2 groups. The Shapiro-Wilk test was used to assess the normal distribution of all variables (α = 0.05), and the values of the 3 indexes were evaluated in both groups using 2 independent samples t-tests or rank sum tests, respectively. The lateral window prepared by the robot group had an area overlap ratio of 0.906 ± 0.038, an area difference of 1.65 (0.51, 2.58) mm<sup>2</sup>, and a center displacement of 0.19 ± 0.09 mm, which was better than those in the freehand group (0.730 ± 0.105, 4.86 (1.22, 6.77) mm<sup>2</sup>, and 1.19 ± 0.60 mm). The difference between the 2 groups was statistically significant (P < 0.05). The task-autonomous dental robot for maxillary sinus lateral window preparation proposed in this study is feasible, and the indexes used to evaluate the accuracy of window preparation are available. The task-autonomous dental robot prepared the lateral window with higher accuracy than the freehand preparation.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhaokun Zhu, Wen Du, Liwei Huang, Hanghang Liu, Zhen Liu, Yao Liu, En Luo
{"title":"CAD/CAM surgical guides and pre-bent distractors: Enhancing precision in MDO for severe dentofacial deformities secondary to TMJ ankylosis.","authors":"Zhaokun Zhu, Wen Du, Liwei Huang, Hanghang Liu, Zhen Liu, Yao Liu, En Luo","doi":"10.1016/j.jcms.2024.11.019","DOIUrl":"https://doi.org/10.1016/j.jcms.2024.11.019","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the different outcomes of mandibular distraction osteogenesis (MDO) using computer-aided design and manufacturing (CAD/CAM) surgical guides accompanied by pre-bent distractors versus CAD/CAM surgical guides with commercial distractors.</p><p><strong>Methods: </strong>Twenty-eight patients with severe dentofacial deformities secondary to unilateral temporomandibular joint ankylosis (TMJA) were retrospectively enrolled. Ten parameters associated with MDO were measured preoperatively, virtually, and postoperatively. The hard-tissue digital model was reconstructed using Mimics Research 17.0, and imaging data were collected and analyzed using Freeform Plus software 12.0, Geomagic Studio 12.0, and IBM SPSS Version 20.0.</p><p><strong>Results: </strong>Twenty-eight patients underwent MDO with subsequent adjunctive surgery and were evaluated. Thirteen patients underwent CAD/CAM surgical guides with pre-bent distractors (group A), while fifteen underwent CAD/CAM guides with commercial distractors (group B). Both techniques achieved optimal occlusion and satisfactory appearance. Statistical analysis showed group A demonstrated a more accurate control of vector direction during MDO compared to group B (p < 0.05). Additionally, group A also exhibited a shorter subsequent treatment duration and less relapse compared to group B (p < 0.05).</p><p><strong>Conclusions: </strong>CAD/CAM surgical guides with pre-bent distractors can significantly enhance surgical accuracy in controlling the vector direction of MDO for correcting dentofacial deformities secondary to TMJA, leading to a reduction in subsequent treatment duration and occurrence.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haoliang Chen , Yongheng Li , Tianyi Lin , Qiang Chen , Yang He
{"title":"Evaluation of grafts fixation techniques for temporomandibular joint reconstruction with medial femoral condyle flap: A numerical study","authors":"Haoliang Chen , Yongheng Li , Tianyi Lin , Qiang Chen , Yang He","doi":"10.1016/j.jcms.2024.09.001","DOIUrl":"10.1016/j.jcms.2024.09.001","url":null,"abstract":"<div><div>Reconstruction for large-scale temporomandibular joint (TMJ) defects can be challenging. Previously, we utilized the medial femoral condyle (MFC) flap for TMJ reconstruction. However, the optimal fixation method remains uncertain. In this study, finite element analysis was used to study the effects of three different fixation types of bone graft: overlap type, bevel type, and flush type. Models of different fixation types of MFC flap were reconstructed from CT images. A standard internal fixation model for extracapsular condylar fracture was also included as a control. Displacement of bone graft, deformation of plates and screws, and stress distribution of plates, screws, and cortical and cancellous of the bone graft were analyzed by finite element analysis to investigate their biomechanical features. The displacement of the bone graft and deformation of plates and screws in three different fixation types showed no significant difference. The overlap type and flush type of fixation displayed the lowest and highest stress respectively. All three fixation types could satisfy the mechanical requirement and face no risk of breakage and the major displacement of the MFC bone graft. These results provide insights into the optimal fixation approach for MFC bone grafts, offering valuable guidance and reference for clinical application.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"52 12","pages":"Pages 1453-1460"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142193730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative analysis of postoperative complications and outcomes in outpatient versus inpatient orthognathic surgery: A retrospective cohort study","authors":"Samanta Buchholzer , Romain Aymon , Benno Rehberg-Klug , Paolo Scolozzi","doi":"10.1016/j.jcms.2024.09.003","DOIUrl":"10.1016/j.jcms.2024.09.003","url":null,"abstract":"<div><div>The purpose of this study was to assess and compare the complication rates of single-jaw orthognathic surgery between outpatients and inpatients, and to examine their impact on the outcome of care setting.</div><div>A retrospective cohort study was performed of patients who underwent single-jaw orthognathic procedures. Outpatients between 2008 and 2023 were selected as the study group, while inpatients between 1997 and 2023 were enrolled as the control group. The predictor variable was the patient care setting. The primary outcome variable was the occurrence of overall complications. Secondary outcomes included surgery-, anesthesia-, and patient-related complications. Other study variables included age, sex, surgery, and anesthetic procedures. Descriptive, bivariate, and multiple logistic regression statistics were computed and the significance level was set at <em>p</em> ≤ 0.05.</div><div>The sample included 307 patients with a mean age of 23.1 years ±9.5 years, of whom 55% were female. The outpatient and inpatient groups consisted of 123 (40.1%) and 184 (59.9%) patients, respectively. Of the 123 outpatients, 104 (85.5%) were discharged on the day of surgery. Age (<em>p</em> = 0.012) and ketamine administration (<em>p</em> = 0.022) were significantly associated with complications among outpatients. Outpatient setting and age were significantly associated with overall complications (OR 2.48; 95% confidence interval [CI] 1.34–4.66, <em>p</em> = 0.003 and OR 0.94, 95% CI 0.88–0.98, <em>p</em> = 0.021, respectively) and anesthetic-related complications (OR 4.43, 95% CI 2.03–10.5, <em>p</em> = 0.0003 and OR 0.92, 95% CI 0.83–0.98, <em>p</em> = 0.041, respectively).</div><div>The study demonstrated that outpatient orthognathic surgery had a high success rate but also identified a higher rate of anesthetic-related complications among outpatients, particularly in younger patients and in those receiving ketamine.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"52 12","pages":"Pages 1461-1468"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142193681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brianne B. Roby , Avery Schnell , Tara L. Johnson , Melissa Scholes , Andrew R. Scott
{"title":"G-tube placement in patients with robin sequence undergoing mandibular distraction osteogenesis: A multi-institutional review","authors":"Brianne B. Roby , Avery Schnell , Tara L. Johnson , Melissa Scholes , Andrew R. Scott","doi":"10.1016/j.jcms.2024.08.023","DOIUrl":"10.1016/j.jcms.2024.08.023","url":null,"abstract":"<div><div>The goal of this study was to investigate the relationship between mandibular distraction osteogenesis (MDO) and rates of postoperative gastrostomy tube (G-tube) placement among patients with isolated and syndromic Robin sequence (RS). This study was a multi-institutional retrospective chart review of patients with RS who underwent MDO at one of three different pediatric tertiary medical centers. The primary aim of the study was to compare rates of G-tube placement following MDO among the three institutions. The primary outcome was analyzed using Fischer's exact test. The secondary aim of the study was to assess for other contributing factors to G-tube placement such as demographic differences, length of hospital stay, and age at MDO. Analysis of secondary outcomes was assessed using multiple logistic regression models. A total of 125 patients met the inclusion criteria, which required RS diagnosis, completion of MDO between 2004 and 2019, and adequate medical record availability. Sixty percent (n = 75) of subjects were categorized as isolated RS (iRS) and forty percent (n = 50) as syndromic RS (sRS). After MDO, 20% (n = 25) of all patients had G-tubes placed. Of the iRS group, 14.7% (n = 11) required a G-tube, while 28% (n = 14) of the sRS group required a G-tube. The post-operative G-tube rate was similar between institutions when considering all patients. When considering only those patients with iRS, the post-MDO G-tube rate at one center was significantly higher than the other two. Overall, most patients with RS did not require a G-tube after MDO, regardless of diagnosis. However, the significant differences in rates of G-tube placement among patients with iRS may indicate differing practice philosophies, surgical protocols, thresholds for G-tube placement, or regional influences between institutions.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"52 12","pages":"Pages 1449-1452"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142193728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christian Doll , Jonas Wüster , Steffen Koerdt , Felix Thiele , Kilian Kreutzer , Carsten Rendenbach , Holger Amthauer , Max Heiland , Claudius Steffen
{"title":"Sentinel lymph node biopsy in early-stage oral squamous cell carcinoma: A retrospective single-center analysis","authors":"Christian Doll , Jonas Wüster , Steffen Koerdt , Felix Thiele , Kilian Kreutzer , Carsten Rendenbach , Holger Amthauer , Max Heiland , Claudius Steffen","doi":"10.1016/j.jcms.2024.08.012","DOIUrl":"10.1016/j.jcms.2024.08.012","url":null,"abstract":"<div><div>Sentinel lymph node biopsy (SLNB) is increasingly incorporated in European national guidelines for the management of the clinically node-negative neck (cN0) in early-stage oral squamous cell carcinoma (OSCC). In Germany, SLNB in OSCCs is not yet routinely performed. This study aimed to evaluate the clinical outcome of SLNB in a German cohort.</div><div>Patients with primary early-stage OSCC who underwent tumor resection and SLNB were retrospectively analyzed. Clinical-pathological characteristics were documented. Primary endpoints were sensitivity and the negative predictive value (NPV).</div><div>A total of 46 patients with a mean age of 62.3 (±14.5) years met the inclusion criteria. Most tumors were located in the tongue (63.0%). Bilateral drainage from a lateral tumor was observed in three cases (6.5%), and sentinel lymph node metastasis was detected in three patients (6.5%). Mean follow-up for all patients was 13.8 months (±9.6). One patient developed regional recurrence following a negative SLNB during the observation period, leading to an NPV of 0.98 and a sensitivity of 75.0%. The 2-year neck-specific relapse-free survival was 92.8%.</div><div>SLNB in early-stage OSCC is a reliable diagnostic tool of the cN0 neck, ensuring a high NPV and RFS. SLNB can be advantageous in comparison to elective neck dissection due to the detection of contralateral lymph drainage.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"52 12","pages":"Pages 1428-1433"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142193727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Justin Haas , Kimberley Yuen , Forough Farrokhyar , Minoo Aminnejad , Connie Williams , Matthew Choi
{"title":"Non-operative interventions for Pierre-Robin sequence: A systematic review and meta-analysis","authors":"Justin Haas , Kimberley Yuen , Forough Farrokhyar , Minoo Aminnejad , Connie Williams , Matthew Choi","doi":"10.1016/j.jcms.2024.08.008","DOIUrl":"10.1016/j.jcms.2024.08.008","url":null,"abstract":"<div><div>Pierre-Robin Sequence (PRS) is a sequence of micrognathia, glossoptosis, and airway obstruction. There is no standardized consensus on the management of respiratory distress for patients with PRS, and operative interventions have associated complications. The purpose of this study is to identify all modalities of non-operative airway intervention for PRS infants. Following PRISMA 2020 guidelines, Embase, Medline, Cochrane, EMCARE, and Web of Science electronic databases were searched from 1992 to 2022 reporting on PRS infants under one year of age who were managed non-operatively. Publications with non-original research designs, an exclusive focus on surgical interventions, case reports, and non-English language articles were excluded. Analysis was performed using non-pooled and pooled proportions (PP). 3280 abstracts were screened, and 88 articles included. Retrospective methodologies were most common. Of the 60 studies where both operative and non-operative interventions were included, 2924 of 4708 PRS infants were administered a non-operative intervention (PP 65.8 % [95%CI 58.5, 72.7]). Reported <em>definitive</em> non-operative interventions, either alone or in combination with another non-operative intervention, included infant positioning (n = 1664), orthodontic appliances (n = 1299), nasopharyngeal tube insertion (n = 983), supplemental oxygen (n = 306), non-invasive ventilation (n = 290), oral airway (n = 46), endotracheal intubation (n = 36), and other (n = 40). The mean MINORS risk of bias score was 6.3 (range 1–12), indicating that the present review was limited by moderate methodological quality for included studies. This is the largest systematic review of non-operative interventions for PRS infants thus far. Most infants are managed non-operatively, with positioning, orthodontic appliances, and nasopharyngeal tubes being the most commonly reported modalities.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"52 12","pages":"Pages 1422-1427"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142193731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Khalid Ayidh Alqahtani , Eman Shaheen , Oliver Da Costa Senior , Constantinus Politis , Reinhilde Jacobs
{"title":"Three dimensional assessment of root changes after multi-segments Le Fort I osteotomy","authors":"Khalid Ayidh Alqahtani , Eman Shaheen , Oliver Da Costa Senior , Constantinus Politis , Reinhilde Jacobs","doi":"10.1016/j.jcms.2024.08.022","DOIUrl":"10.1016/j.jcms.2024.08.022","url":null,"abstract":"<div><div>The primary purpose of this study was to accurately assess linear, volumetric and morphological changes of maxillary teeth roots following multi-segments Le Fort I osteotomy. A secondary objective was to assess whether patient- and/or treatment-related factors might influence root remodeling. A total of 60 patients (590 teeth) who underwent combined orthodontic and orthognathic surgery were studied retrospectively. The multi-segments group included 30 patients who had either 2-segments or 3-segments Le Fort I osteotomy. The other 30 patients underwent one-segment Le Fort I osteotomy. Preoperative, 1 year, and 2 years postoperative cone beam computed tomography (CBCT) scans were obtained. A validated and fully automated method for evaluating root changes in three dimensions (3D) was applied. No statistical significant differences were found between multi-segments and one-segment Le Fort I for linear, volumetric and morphological measurements. The Spearman correlation coefficient revealed a positive relationship between maxillary advancement and root remodeling, with more advancement leading to more root remodeling. This research may allow surgeons to properly assess root remodeling after combined treatment of orthodontics and the different Le Fort I osteotomies.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"52 12","pages":"Pages 1485-1490"},"PeriodicalIF":2.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142249950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}