Journal of Cranio-Maxillofacial Surgery最新文献

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A minimally invasive modified revolving-door flap for surgical reconstruction of concha and antihelix defects 一种微创改良旋转门皮瓣用于鼻甲及反螺旋缺损的外科重建。
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-02-01 DOI: 10.1016/j.jcms.2024.11.006
Mario Santagata , Camila Scharf , Andrea Battisti , Valentino Valentini , Gianpaolo Tartaro , Luigi Rugge , Fabrizio Chirico
{"title":"A minimally invasive modified revolving-door flap for surgical reconstruction of concha and antihelix defects","authors":"Mario Santagata ,&nbsp;Camila Scharf ,&nbsp;Andrea Battisti ,&nbsp;Valentino Valentini ,&nbsp;Gianpaolo Tartaro ,&nbsp;Luigi Rugge ,&nbsp;Fabrizio Chirico","doi":"10.1016/j.jcms.2024.11.006","DOIUrl":"10.1016/j.jcms.2024.11.006","url":null,"abstract":"<div><div>Skin cancers affecting the concha and antihelix are quite common, because of anterior auricular projection from the head and subsequent actinic exposure, leading to the need for effective ear reconstruction post-surgery. Various methods such as skin grafts, free tissue transplantation, and local flaps have been used. This study introduces a refined technique for concha-antihelix defect reconstruction, based on a minimally invasive modification of the revolving-door flap procedure. Here, a fasciocutaneous flap technique involving minimal posterior auricular muscle contribution is used, particularly suitable for anterior skin and cartilage defects. The study included 75 patients with nonmelanocytic skin carcinoma on the ear's anterior surface, in which we evaluated patient's and surgeon's satisfaction with a visual analogue scale and discussed the surgical technique and its advantages and indications. The technique demonstrated excellent cosmetic and functional outcomes, effectively hiding donor-site deformities and ensuring patient and surgeon contentment. This approach allows for one-stage reconstruction under local anesthesia, reducing costs, surgery time, and recovery period. The procedure provides high-quality tissue for reconstruction with low complication risks, making it an optimal choice for wide conchal and antihelix defect repairs due to its proximity to the affected area and the reliable, swift nature of the method.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 2","pages":"Pages 181-187"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unmasking self-citations: A critical analysis using maxillofacial surgery literature as example 揭开自我引用的面纱:以颌面外科文献为例进行批判性分析。
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-02-01 DOI: 10.1016/j.jcms.2024.11.013
Ricardo Grillo , Bruno Alvarez Quinta Reis , Bernardo Correia Lima , Leonardo Augustus Peral Ferreira Pinto , Fernando Melhem-Elias
{"title":"Unmasking self-citations: A critical analysis using maxillofacial surgery literature as example","authors":"Ricardo Grillo ,&nbsp;Bruno Alvarez Quinta Reis ,&nbsp;Bernardo Correia Lima ,&nbsp;Leonardo Augustus Peral Ferreira Pinto ,&nbsp;Fernando Melhem-Elias","doi":"10.1016/j.jcms.2024.11.013","DOIUrl":"10.1016/j.jcms.2024.11.013","url":null,"abstract":"<div><div>Bibliometric analysis serves as a potent tool for deciphering the intricacies of scholarly communication and academic impact, contributing to an observable surge in publications of this nature. The objective of this study is to conduct a bibliometric analysis of self-citation in Maxillofacial Surgery (MFS) literature. The retrospective study adheres to the principles outlined in the Leiden Manifesto, utilizing Web of Science and Scopus databases for a robust analysis. Various bibliometric indicators, including H-index, MFS-related articles, and citing articles, are considered, with a focus on the impact of self-citation. The extensive bibliographic search retrieved 70,288 articles, allowing for the identification of 200 prolific authors from 25 countries in MFS literature. Despite potential limitations in sample size and retrospective nature, the study provides valuable insights. Notably, the self-citation rate stood at 46.94%, prompting a nicety examination of its impact on bibliometric indicators. Changes in H-index, exclusive MFS articles, and total publications exhibited low correlations with self-citation frequency, highlighting the complexity of this phenomenon. The study emphasizes the nuanced impact of self-citation on bibliometric indicators, cautioning against demonization and advocating for a balanced and individual perspective. The findings highlight the intricate link between self-citation, high productivity, expertise, and the specific dynamics of emerging research fields within MFS.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 2","pages":"Pages 134-141"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of a nomogram to predict the probability of survival in hypopharyngeal squamous cell cancer based on systemic inflammation and nutritional indicators 基于全身炎症和营养指标,开发下咽鳞状细胞癌生存概率预测提名图。
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-02-01 DOI: 10.1016/j.jcms.2024.11.001
Ce Wu , Feng Xie , Kai Sun, Liwei Jiang, Zhenju Xu, Xudong Yan, Lin Wang, Longgang Yu, Yan Jiang
{"title":"Development of a nomogram to predict the probability of survival in hypopharyngeal squamous cell cancer based on systemic inflammation and nutritional indicators","authors":"Ce Wu ,&nbsp;Feng Xie ,&nbsp;Kai Sun,&nbsp;Liwei Jiang,&nbsp;Zhenju Xu,&nbsp;Xudong Yan,&nbsp;Lin Wang,&nbsp;Longgang Yu,&nbsp;Yan Jiang","doi":"10.1016/j.jcms.2024.11.001","DOIUrl":"10.1016/j.jcms.2024.11.001","url":null,"abstract":"<div><div>The prognostic significance of various systemic inflammatory and nutritional markers in hypopharyngeal squamous cell carcinoma (HPSCC) remains unclear. This study aimed to develop a nomogram to predict survival probabilities in patients undergoing HPSCC resection surgery based on these markers, which could help in the treatment of HPSCC.</div><div>The study included data from 236 HPSCC patients. The most predictive systemic inflammatory and nutritional markers were identified through the area under the prognostic curve (AUC). Using COX regression analysis, independent risk factors were pinpointed and used to create and validate a predictive nomogram.</div><div>The cut-off values of systemic immune-inflammatory index (SII) and advanced lung cancer inflammatory index (ALI) were 27.80 and 791.35, respectively. The constructed nomogram incorporated tumor stage, age, ALI, and SII. The AUC values for 1-year, 3-year, and 5-year survival prediction were 0.820, 0.721, and 0.723, respectively. Calibration and decision curves demonstrated the substantial clinical utility of the model.</div><div>SII and ALI possess significant prognostic importance in HPSCC. The developed nomogram, which includes these markers, offers a practical tool for estimating patient survival probabilities, aiding physicians in clinical decision-making for high-risk patients.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 2","pages":"Pages 90-96"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D analysis of long-term airway evolution following orthognathic approach of bimaxillary setback surgery without segmental osteotomy 采用正颌法进行双颌后凸手术后长期气道演变的三维分析,无节段截骨术。
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-02-01 DOI: 10.1016/j.jcms.2024.11.011
Yao Yang, Yinghua Jia, Qi Liu, Piao Wang, Hexiu Jin, Xuejiu Wang
{"title":"3D analysis of long-term airway evolution following orthognathic approach of bimaxillary setback surgery without segmental osteotomy","authors":"Yao Yang,&nbsp;Yinghua Jia,&nbsp;Qi Liu,&nbsp;Piao Wang,&nbsp;Hexiu Jin,&nbsp;Xuejiu Wang","doi":"10.1016/j.jcms.2024.11.011","DOIUrl":"10.1016/j.jcms.2024.11.011","url":null,"abstract":"<div><div>Long-term evolution of airway space following bimaxillary setback surgery has been seldom reported. 31 patients with bimaxillary protrusion were included in this study. Bimaxillary setback surgery without segmental osteotomy were performed to alleviate their facial deformity. The pharyngeal airway volume and most constricted airway cross-sectional areas before surgery (T0), one week (T1), and one year (T2) after surgery were measured by 3D image analysis depending on CT data. To exclude the impact of post operational swelling on the airway analysis, the airway changes of another cohort of 10 orthognathic patients without sagittal maxilla or mandible movements were also measured as a control. Body mass index (BMI) was noted and analyzed as well to rule out its interference. Results showed that, in bimaxillary setback surgery patients, no post operational upper pharyngeal airway sleep disorders (UASD) occurred. The mean ± SD of pharyngeal airway volume (PAV) and the minimum cross-sectional area (Min-CSA) at T0 were 14921.3 ± 3910.1 mm<sup>3</sup> and 147.9 ± 75.8 mm<sup>2</sup>, reduced to 11834.1 ± 3916.3 mm<sup>3</sup>(79.3%, P &lt; 0.001) and 111.6 ± 60.6 mm<sup>2</sup>(75.4%, P &lt; 0.001 at T1, and recovered to 14686.8 ± 3917.1 mm<sup>3</sup>(97.1%, P &lt; 0.001) and 132.7 ± 62.8 mm<sup>2</sup> (89.6%, P &lt; 0.001) at T2. In control group patients, the mean ± SD of PAV were 16540 ± 5518 mm<sup>3</sup> at T0 vs 14248 ± 4340 mm<sup>3</sup> at T1 (P = 0.051) and Min-CSA were 156 ± 61 mm<sup>2</sup>(T0) vs159 ± 61 mm<sup>2</sup> at T1 (P = 0.849). Besides, At T0 and T2, the mean ± SD of the BMI was 20.19 ± 1.80 and 20.04 ± 2.53 respectively (P = 0.772). This study suggests that Orthognathic bimaxillary setback reduce the pharyngeal airway space. However, the reduction will largely alleviate in long-term. Aesthetic oriented bimaxillary setback approach is relatively safe when the setback distance is controlled appropriately.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 2","pages":"Pages 122-128"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histomorphometric outcome following sinus floor augmentation with allogeneic adipose tissue-derived stem cells. A randomized controlled experimental study 使用异体脂肪组织来源干细胞进行窦底增量术后的组织形态学结果。随机对照实验研究。
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-02-01 DOI: 10.1016/j.jcms.2024.11.008
Thomas Starch-Jensen , Hanna Aludden , Christer Dahlin , Niels Henrik Bruun , Trine Fink
{"title":"Histomorphometric outcome following sinus floor augmentation with allogeneic adipose tissue-derived stem cells. A randomized controlled experimental study","authors":"Thomas Starch-Jensen ,&nbsp;Hanna Aludden ,&nbsp;Christer Dahlin ,&nbsp;Niels Henrik Bruun ,&nbsp;Trine Fink","doi":"10.1016/j.jcms.2024.11.008","DOIUrl":"10.1016/j.jcms.2024.11.008","url":null,"abstract":"<div><div>The aim of this pre-clinical study was to test the hypothesis of no difference in histomorphometric outcome following sinus floor augmentation (SFA) with allogeneic adipose tissue-derived stem cells (AASCs) seeded on deproteinized bovine bone mineral (DBBM) (test) compared with excipient on DBBM (control). Eighteen minipigs were allocated into three groups of six animals and euthanised after one month (T1), two months (T2), and four months (T3). The sinuses of each animal were randomly assigned to either test or control with identical graft volume. Percentage of newly formed bone (NFB), non-mineralized tissue, residual DBBM, and bone-to-implant contact (BIC) were estimated by histomorphometric analysis in a randomly selected region of interest and summarized as mean percentage with 95% confidence interval. Test group, mean percentage of NFB and BIC was 8.8 and 19.5 (T1), 17.7 and 23.2 (T2), 37.1 and 30.4 (T3). Control group, corresponding values were 8.9 and 13.9 (T1), 18.7 and 23.3 (T2), 36.8 and 36.6 (T3). There were no significant differences in NFB or BIC at T1 (P = 0.964; 0.551), T2 (P = 0.927; 0.992), and T3 (P = 0.971; 0.557) between test or control. Percentage of NFB was significantly higher at T3 compared with T1, in test (P = 0.001) and control (P = 0.004), while no significant difference in BIC was disclosed between T1, T2, and T3, in test and control, respectively. In conclusion, adding AASCs to DBBM seem not to improve NFB or BIC compared with DBBM alone in conjunction with SFA.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 2","pages":"Pages 104-113"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic findings predictive of obstructive sleep apnea in adults: A systematic review and meta-analysis 预测成人阻塞性睡眠呼吸暂停的影像学表现:一项系统回顾和荟萃分析。
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-02-01 DOI: 10.1016/j.jcms.2024.11.003
Sobhi Kazmouz , Nathan Calzadilla , Akriti Choudhary , Lander Scotte McGinn , Austin Seaman , Chad A. Purnell
{"title":"Radiographic findings predictive of obstructive sleep apnea in adults: A systematic review and meta-analysis","authors":"Sobhi Kazmouz ,&nbsp;Nathan Calzadilla ,&nbsp;Akriti Choudhary ,&nbsp;Lander Scotte McGinn ,&nbsp;Austin Seaman ,&nbsp;Chad A. Purnell","doi":"10.1016/j.jcms.2024.11.003","DOIUrl":"10.1016/j.jcms.2024.11.003","url":null,"abstract":"<div><div>Polysomnography remains the diagnostic gold standard for obstructive sleep apnea (OSA), but it cannot be easily performed in a timely fashion within the practice of a craniomaxillofacial surgeon. Hence, in this systematic review and meta-analysis, we aimed to identify radiographic indicators that could predict obstructive sleep apnea (OSA) diagnosis. We conducted a PRISMA-compliant systematic review and meta-analysis, including 109 studies with 9817 participants (3509 controls, 6308 OSA patients), predominantly male (79% controls, 85% OSA patients). The analysis focused on CT (36, 33%), MRI (23, 21%), and lateral cephalogram findings (50, 46%). The average age and BMI for the included patients were 44.4 ± 14.4 years and 26.4 ± 5.2 kg/m<sup>2</sup> for controls, and 51.5 ± 40.4 years and 29.8 ± 6.4 kg/m<sup>2</sup> for the OSA group. A random-effects model meta-analysis was conducted on the measurements that met our criteria. Due to measurement differences between studies, only lateral cephalogram measurements could be included in the meta-analysis: OSA correlated with increased soft palate length and thickness, increased mandibular plane to hyoid bone distance, and decreased SNA, SNB, BaSN, SN distance, and palatal length (ANS-PNS). Although the study underscores radiographic utility for screening, PSG is necessary to establish a diagnosis of OSA.</div></div>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":"53 2","pages":"Pages 162-180"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D evaluation of changes in mandibular condyle morphology following orthognathic surgery in patients with maxillomandibular asymmetry: A retrospective study.
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-01-30 DOI: 10.1016/j.jcms.2025.01.006
Mustafa Burak Kirişci, Emre Tosun, Hakan Hıfzı Tüz, Canseda Avağ, Arda Büyüksungur, Mehmet Hakan Kurt
{"title":"3D evaluation of changes in mandibular condyle morphology following orthognathic surgery in patients with maxillomandibular asymmetry: A retrospective study.","authors":"Mustafa Burak Kirişci, Emre Tosun, Hakan Hıfzı Tüz, Canseda Avağ, Arda Büyüksungur, Mehmet Hakan Kurt","doi":"10.1016/j.jcms.2025.01.006","DOIUrl":"https://doi.org/10.1016/j.jcms.2025.01.006","url":null,"abstract":"<p><p>Symmetry is integral for the balance and function of the craniofacial complex and making precise diagnosis of asymmetric craniofacial structures is crucial for treatment planning. This study focuses on maxillomandibular asymmetry, examining its impact on condylar resorption and trabecular bone morphology changes following orthognathic surgery. Cone-beam computed tomography (CBCT) scans of patients with and without asymmetry were analyzed pre- and post-surgery. The deviation group exhibited significant decreases in bone volume (BV) and trabecular thickness (TB.TH), indicating condylar resorption. Non-deviation group showed a significant decrease in TB.TH post-surgery. Interestingly, fractal dimension (FD) increased post-surgery across all groups, indicating increased trabecular bone density. Pairwise comparisons revealed significant differences in BV_CHANGE between deviation and non-deviation groups, suggesting greater resorptive activity in deviated condyles. Additionally, gender-based analyses showed significant differences in BV_CHANGE between males and females. These findings highlight the complexity of condylar changes post-surgery, particularly in asymmetric cases, shedding light on potential implications for temporomandibular joint (TMJ) health. Consideration of factors such as asymmetry direction, patient gender, and bone adaptation capacity are crucial in understanding post-surgical outcomes and potential TMJ implications in maxillomandibular asymmetry patients undergoing orthognathic surgery.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The efficacy of different local flaps for wound closure of defects after removal of necrotic bone in advanced medication-related osteonecrosis of the jaw: A single-center cohort study.
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-01-30 DOI: 10.1016/j.jcms.2024.12.019
Yoshinari Myoken, Takeshi Kawamoto, Yoshinori Fujita, Seiya Hayashi, Shigeaki Toratani, Souichi Yanamoto
{"title":"The efficacy of different local flaps for wound closure of defects after removal of necrotic bone in advanced medication-related osteonecrosis of the jaw: A single-center cohort study.","authors":"Yoshinari Myoken, Takeshi Kawamoto, Yoshinori Fujita, Seiya Hayashi, Shigeaki Toratani, Souichi Yanamoto","doi":"10.1016/j.jcms.2024.12.019","DOIUrl":"https://doi.org/10.1016/j.jcms.2024.12.019","url":null,"abstract":"<p><p>For this study, the surgical outcomes of patients with advanced medication-related osteonecrosis of the jaw (MRONJ), treated with different local flaps for soft-tissue closure, were evaluated. Cases of stage 2 and 3 MRONJ patients (n = 96) with a 12-month minimum follow-up were retrospectively analyzed. All patients underwent surgical treatment and soft-tissue closure with local flaps, including buccal fat flap (BFF), nasolabial flap (NLF), facial artery musculomucosal flap (FAMM-F), and submental island flap (SIF), based on the size and location of the defects. The occurrence of side effects was also evaluated. At the time of the last follow-up, 97.7% (42 of 43) of the patients in the BFF group, 90.3% (28 of 31) of the NLF patients, 100% (8 of 8) of the FAMM-F patients, and 92.9% (13 of 14) of the SIF patients showed mucosal integrity. No serious complications were observed. Five cases with relapsed MRONJ were in cancer patients who continued both chemotherapy and antiresorptive therapy. Different local flaps for soft-tissue closure after bone surgery in advanced MRONJ patients could provide a mechanically stable and well-vascularized covering of the exposed bone, leading to good healing.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immobilization of biofunctional molecule with potential osteoinductive efficacy on titanium implant for promoting early-stage osseointegration.
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-01-29 DOI: 10.1016/j.jcms.2025.01.018
Bai-Hung Huang, Hung-Yang Lin, Yu-Sin Ou, Wen-Chien Lan, Chi-Hsun Tsai, Takashi Saito, Hsieh-Tsung Shen, Wayne Chen, Chung-Ming Liu, Hiroyuki Nakano
{"title":"Immobilization of biofunctional molecule with potential osteoinductive efficacy on titanium implant for promoting early-stage osseointegration.","authors":"Bai-Hung Huang, Hung-Yang Lin, Yu-Sin Ou, Wen-Chien Lan, Chi-Hsun Tsai, Takashi Saito, Hsieh-Tsung Shen, Wayne Chen, Chung-Ming Liu, Hiroyuki Nakano","doi":"10.1016/j.jcms.2025.01.018","DOIUrl":"https://doi.org/10.1016/j.jcms.2025.01.018","url":null,"abstract":"<p><p>In the present study, porcine-derived collagen type I was covalently immobilized on the surface of titanium (Ti) implants via carboxyl groups introduced by bonded p-vinylbenzoic acid to investigate its in vitro biocompatibility with gingival stem cells and in vivo bone regeneration behavior in the edentulous ridges of Lanyu small-ear pigs at weeks 2 and 6 (short-term effectiveness) through micro-computed tomography and histological analysis. Analytical results found that gingival stem cells showed effective adhesion and spreading on these collagen-immobilized implant surfaces. After 2 and 6 weeks of healing, significant differences in Hounsfield units were observed among the control (week 2 (674.2 ± 79.9) ∗∗p < 0.01 and week 6 (596.4 ± 49.6) ∗∗p < 0.01), buffer-coated implant (week 2 (768.1 ± 68.7) ∗p < 0.05 and week 6 (720.4 ± 62.6) ∗p < 0.05), and collagen-immobilized implant (week 2 (828.2 ± 69.4) and week 6 (907.4 ± 63.5)) groups. No significant differences in bone-to-implant contact ratios were discovered between the investigated groups. However, the bone surface area results demonstrated an enhanced bone apposition for the collagen-immobilized implants compared to the control and buffer-coated implants at weeks 2 and 6 post-implantation (∗p < 0.05). Therefore, this preclinical study underscores the advantageous impact of collagen immobilization on Ti implant surfaces for clinical application, substantiating its effectiveness through significant evidence of improved osseointegration at early-stages.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of mandibular condyle fractures with a rhombic 3D condylar fracture plate - Does the surgical approach matter?
IF 2.1 2区 医学
Journal of Cranio-Maxillofacial Surgery Pub Date : 2025-01-29 DOI: 10.1016/j.jcms.2025.01.029
Henry Leonhardt, Jan Bernard Matschke, Christian Bräuer, Bernhard Remschmidt, Niall M H McLeod, Günter Lauer, Adrian Franke
{"title":"Treatment of mandibular condyle fractures with a rhombic 3D condylar fracture plate - Does the surgical approach matter?","authors":"Henry Leonhardt, Jan Bernard Matschke, Christian Bräuer, Bernhard Remschmidt, Niall M H McLeod, Günter Lauer, Adrian Franke","doi":"10.1016/j.jcms.2025.01.029","DOIUrl":"https://doi.org/10.1016/j.jcms.2025.01.029","url":null,"abstract":"<p><p>Fractures involving the mandibular condyle are a significant subset of mandibular fractures, demanding specialized implant design considerations for effective surgical treatment. The core objective of this study was to assess the clinical and radiographic results in patients treated with a single rhombic-shaped implant according to the surgical approach used. This retrospective cohort investigation, spanning a ten-year recruitment window, included individuals with unilateral fractures who underwent surgical treatment with a rhombic-shaped implant. These patients were subject to follow-up examinations at one, three, and six months post-surgery, along with corresponding orthopantomograms and clinical assessments. Patients were allocated into four groups depending on the fracture pattern and level as well as the approach used for fracture treatment. The primary outcome variables under scrutiny encompassed parameters such as occlusion, maximum interincisal distance, mandibular excursion across different postoperative time points, and radiographic measurements of mandibular height and the gonion angle. A total of 236 patients, comprising 161 males and 75 females, with an average age of 40.2 ± 19.2 years, were included in the study. Satisfactory occlusion was exhibited in 99.6% of patients at the six-month follow-up. Furthermore, all parameters associated with mandibular excursion displayed significant enhancements (p < 0.01). These improvements were accompanied by a reduction in ramus height and increased gonion angle on the fractured side. The investigation of the clinical and radiographic results suggest a tendency of the choice of the approach depending on the fracture pattern, but no statistically significant recommendations could be identified.</p>","PeriodicalId":54851,"journal":{"name":"Journal of Cranio-Maxillofacial Surgery","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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