{"title":"The effectiveness of hand therapy for breast cancer survivors experiencing aromatase inhibitor-associated musculoskeletal syndrome in the hands and wrists.","authors":"Wanda Weimer, Miriam Sleven","doi":"10.1016/j.jht.2025.01.007","DOIUrl":"https://doi.org/10.1016/j.jht.2025.01.007","url":null,"abstract":"<p><strong>Background: </strong>Musculoskeletal problems, or aromatase inhibitor-associated musculoskeletal syndrome, in the hands and wrists is a known side effect of aromatase inhibitor medication, often prescribed for 5years or more for breast cancer survivors. No studies were found on the effectiveness of hand therapy for breast cancer survivors experiencing aromatase inhibitor-associated musculoskeletal syndrome in the hands and wrists.</p><p><strong>Purpose: </strong>The primary objective of this study is to determine the effectiveness of hand therapy on reducing hand and wrist pain, improving grip strength, improving upper extremity function, and improving health related quality of life in breast cancer survivors diagnosed with aromatase inhibitor-associated musculoskeletal syndrome in the hands and wrists.</p><p><strong>Study design: </strong>Longitudinal case series.</p><p><strong>Methods: </strong>A pre-post design was used to compare the results of standardized testing from initial evaluation to discharge. Participants were evaluated using standard hand therapy methods. Outcome measurements studied were pain levels, grip strength, upper extremity function, and breast cancer health related quality of life, measured with a patient-reported outcome measure specific to this population. A multimodal client centered treatment plan was utilized with each participant. Frequency and duration of the treatment was determined through collaboration with the participant.</p><p><strong>Results: </strong>Thirty-two participants enrolled and 29 completed the study. Comparison of pre and post data for all four outcome measures revealed statistically significant improvements (p<0.05). Cohen's d analysis demonstrated large effect for pain, moderate effects for upper extremity function and health related quality of life, and low effect for grip strength. Trigger finger was noted to be present in 62.1% of participants.</p><p><strong>Conclusions: </strong>This study demonstrates that hand therapy resulted in statistically and clinically significant improvement in pain, grip strength, upper extremity function, and health related quality of life. The results support the effectiveness of hand therapy for breast cancer survivors experiencing aromatase inhibitor-associated musculoskeletal syndrome in the hands and wrists.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of three traditional conservative treatment techniques on patients with mild-to-moderate carpal tunnel syndrome: A systematic review and meta-analysis.","authors":"Jiatao Zhang, Jiahuan Chen, Xiang Li, Ziyang Yan, Qiaoxia Zhang, Pincao Gao, Fang Tang","doi":"10.1016/j.jht.2025.01.001","DOIUrl":"https://doi.org/10.1016/j.jht.2025.01.001","url":null,"abstract":"<p><strong>Background: </strong>Carpal tunnel syndrome (CTS) is a common peripheral nerve entrapment syndrome that can be treated in a variety of ways, including manual therapy, massage, and acupuncture.</p><p><strong>Purpose: </strong>Traditional conservative treatment techniques have been widespread used for treatment of patients with mild-to-moderate carpal tunnel syndrome (CTS), such as manual therapy, massage, and acupuncture. However, there appears to be no consensus about the benefits of traditional conservative treatment techniques for patients with CTS. This systematic review and meta-analysis were aimed to analyze the effectiveness of three traditional conservative treatment techniques (manual therapy, massage, and acupuncture) on the patients with mild-to-moderate CTS.</p><p><strong>Study design: </strong>Intervention systematic review with meta-analysis.</p><p><strong>Methods: </strong>Randomized controlled clinical trails were searched from the inception of PubMed, Web of Science and CNKI up to May 22, 2024. Mean differences (MD) or standardized mean differences (SMD) were used as effect sizes by us and 95% confidence intervals (CI) were used to analyze these studies. Analyses were performed using RevMan 5.3 software. Funnel plots and Egger's test were used to assess publication bias.</p><p><strong>Results: </strong>A total of 14 articles with 1110 patients with mild-to-moderate CTS satisfied the inclusion criteria in this systematic review and meta-analysis. The meta-analysis found that the three traditional conservative treatment techniques can significantly reduce the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) [MD = -1.55, 95% CI (-2.15, -0.95), p < 0.00001], Symptom Severity Scale (SSS) [MD = -0.90, 95% CI (-1.28, -0.51), p < 0.00001], Functional Status Scale (FSS) [MD = -0.85, 95% CI (-1.17, -0.54), p < 0.00001] and pain [SMD = -2.03, 95% CI (-2.75, -1.30), p < 0.00001] scores, and improve sensory nerve conduction velocity (SNCV) [MD = 5.37, 95% CI (2.43, 8.32), P = 0.0004] compared with the control group.</p><p><strong>Conclusions: </strong>This study demonstrated that three traditional conservative treatment techniques can effectively improve the severity of symptoms, functional status, pain levels, and sensory nerve conduction velocity on patients with mild-to-moderate CTS.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Purdue manual dexterity testing: Normative data from young people from Turkey.","authors":"Aylin Yalçın Irmak, Aysun Perim Ketenciler","doi":"10.1016/j.jht.2025.02.012","DOIUrl":"https://doi.org/10.1016/j.jht.2025.02.012","url":null,"abstract":"<p><strong>Background: </strong>The Purdue Pegboard Test (PPT) is a widely used tool to measure manual dexterity. Since manual dexterity is highly important for participation in education and the workforce, determining its normative values within specific age categories and cultural contexts is of critical importance.</p><p><strong>Purpose: </strong>The aim of the study was to determine normative values for manual dexterity in young people and to investigate the relationship between these values and certain determinants.</p><p><strong>Study design: </strong>A cross-sectional study.</p><p><strong>Methods: </strong>A total of 774 young participants attending selected schools participated in the study using a convenience sampling method. The participants' manual dexterity was assessed using the PPT, including tasks for the right-left hand, both hands, and assembly tasks. Mean scores were analyzed using an independent-sample t-test and one-way Anova test of variance.</p><p><strong>Results: </strong>It was found that participants performed better in manual dexterity when using their dominant hands, female gender, and increasing age. There was no significant difference in PPT test scores based on the number of siblings or the presence of chronic illness (p > 0.05). Regarding regular sports participation, there was a significant difference in mean scores for PPT right and left hand tasks in favor of those who engage in regular sports (p < 0.05), while there was a significantly greater difference between both hands and assembly tasks (p < 0.01). There was a significant difference in mean scores for PPT right hand tasks in favor of those who regularly play musical instruments (p < 0.05).</p><p><strong>Conclusions: </strong>The results provide normative data that can be used to assess the manual dexterity of young people. It is believed that systematically examining the manual dexterity of young individuals and evaluating it in the context of the presented normative values will contribute to the early detection of deficiencies and impairments that may negatively affect productivity and the acquisition of vocational skills.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jean Paul Brutus, Alison Taylor, Natasha Barone, Elisabet Hagert
{"title":"Extensor mechanism dysfunction and hand deformities caused by Dupuytren's disease: Surgical and rehabilitation perspectives.","authors":"Jean Paul Brutus, Alison Taylor, Natasha Barone, Elisabet Hagert","doi":"10.1016/j.jht.2024.12.017","DOIUrl":"https://doi.org/10.1016/j.jht.2024.12.017","url":null,"abstract":"<p><p>Dupuytren's disease is a common fibroproliferative disorder that primarily affects the palm of the hand. While the disease is known for its characteristic palmar contractures, it also has a potential impact on the extensor mechanism of the hand, resulting in the development of boutonniere deformity, swan-neck deformity, and persistent metacarpophalangeal joint contracture due to extensor capsule stretching and tendon instability. These imbalances are challenging to correct under general or regional anesthesia. Wide awake local anesthesia without a tourniquet allows active range of motion and intraoperative patient collaboration. By understanding the underlying mechanisms and structures involved in these deformities and correcting them under local anesthesia without a tourniquet, hand surgeons can become more confident in correcting the deformity, demonstrating it to the patient, optimizing the rehabilitation protocol, and improving patient outcomes.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vicenç Punsola-Izard, Karen S Schultz, Manuel Llusà-Perez, Aroa Casado
{"title":"Prioritize proximal interphalangeal joint extension, a cadaver study clarifying PIPJ neutral position and joint capsular behavior.","authors":"Vicenç Punsola-Izard, Karen S Schultz, Manuel Llusà-Perez, Aroa Casado","doi":"10.1016/j.jht.2024.12.015","DOIUrl":"https://doi.org/10.1016/j.jht.2024.12.015","url":null,"abstract":"<p><strong>Background: </strong>Dysmobility of the proximal interphalangeal joint (PIPJ) often arises following trauma, inflammation, or surgery, leading to joint stiffness and reduced range of motion. This condition results from capsular shortening and the development of arthrofibrosis, which restricts mobility and contributes to contracture formation.</p><p><strong>Purpose: </strong>This study investigates the influence of joint position on capsular space volume distribution in the PIPJ, hypothesizing that the mid-flexion position maximizes capsular space, contributing to ligament shortening and arthrofibrosis. This study investigates the influence of joint position on capsular space volumen distribution in PIPJ, hypothesizing that the mid- flexion position maximizes capsular space, contributing to ligament shortening and arthrofibrosis.</p><p><strong>Study design: </strong>A cadaveric study examining capsuloligamentous dynamics of the PIPJ across various joint positions.</p><p><strong>Methods: </strong>Fifteen fingers from five fresh frozen cadaver specimens were evaluated through three studies: RESULTS: 1. The PIPJ demonstrated close-packed positions at full flexion and extension, with maximum capsular space volume observed in the mid-flexion position (30°-40° flexion). 2. Silicone injection consistently held the joint in a mid-flexion position, indicating maximal capsular volume. 3. Latex distribution varied with joint position, concentrating dorsally in extension, spreading equally volar-dorsal in mid-flexion and shifting volarly in flexion.</p><p><strong>Conclusions: </strong>We propose call to call the mid-flexion position (of 30º-40º flexion) the \"neutral\" position. This position maximizes capsular space volume, facilitating ligament shortening and arthrofibrosis. Extension minimizes volar capsularspace volume and may be essential for preventing flexion contractures. Clinically, immobilizing the proximal interphalangeal joint in extension with dorsal compression may help prevent contracture and reduce edema, while manual therapy should target the mid-flexion position to enhance joint mobilization.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The arm curl score is the best indicator of reduced upper extremity exercise capacity in women with fibromyalgia: A cross-sectional study.","authors":"Habibe Durdu, Ulku Kezban Sahin, Ilker Fatih Sari","doi":"10.1016/j.jht.2024.12.012","DOIUrl":"https://doi.org/10.1016/j.jht.2024.12.012","url":null,"abstract":"<p><strong>Background: </strong>Unsupported upper extremity exercise capacity (UUEEC) is crucial for sustaining everyday functions; whether it is compromised in the fibromyalgia (FM) population is unknown.</p><p><strong>Purpose: </strong>The study aimed to assess UUEEC in women with FM and to determine associated factors.</p><p><strong>Study design: </strong>This is a cross-sectional study.</p><p><strong>Methods: </strong>This study was conducted with 48 women with FM and 48 healthy women between the ages of 18-65. UUEEC, muscle strength, flexibility and disability of upper extremity, disease severity, pain catastrophizing, and quality of life assessed with the Six Minute Pegboard and Ring Test (6PBRT), arm curl test, hand grip strength test, back-scratch test, Disability of Arm, Shoulder, and Hand (DASH), Fibromyalgia Impact Questionnaire (FIQ) and Pain Catastrophizing Scale and Short-form 36 questionnaires, respectively.</p><p><strong>Results: </strong>The 6PBRT score was significantly decreased in the women with FM compared to healthy women (p < 0.001, Cohen d: 1.28). The multivariate linear regression analysis revealed that the model incorporating the arm curl score, hand grip strength, DASH, and FIQ scores was explained 68% of the variance in 6PBRT score (R<sup>2</sup> = 0.672, p < 0.001). The results indicated that all variables in the model were independent predictors of 6PBRT score, with the arm curl score was the strongest predictor (β = 6.36, p = 0.015).</p><p><strong>Conclusions: </strong>This study suggests that UUEEC measured by 6PBRT is reduced in women with FM, and the upper extremity muscle strength is closely related to the 6PBRT score. Accordingly, strengthening the biceps brachii muscle in women with FM, whose muscle weakness is common, may be effective in improving UUEEC, which is directly associated to daily activities.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Finger flexor tendon injuries repaired surgically followed by an early active motion program: A prospective cohort study of clinician- and patient-reported outcomes.","authors":"Nicola Williams, Madelaine Carey, Kathy Stiller","doi":"10.1016/j.jht.2024.12.011","DOIUrl":"https://doi.org/10.1016/j.jht.2024.12.011","url":null,"abstract":"<p><strong>Background: </strong>Finger flexor tendon injuries are usually surgically repaired followed by early active motion rehabilitation. Studies have focussed on clinician-reported outcomes after these injuries.</p><p><strong>Purpose: </strong>To measure clinician- and patient-reported outcomes after finger flexor tendon repair.</p><p><strong>Study design: </strong>Prospective cohort study.</p><p><strong>Methods: </strong>Adult patients with traumatic, finger flexor tendon injuries who underwent surgical repair were recruited. An individualized, early active motion rehabilitation program was provided, including an orthosis, progressive active/passive range of motion (ROM) and strengthening exercises. Clinician-reported outcomes, namely total active motion (TAM), Strickland-Glogovac ROM, flexor/extensor deficits, and grip strength, were recorded 3 months post-injury. Patient-reported outcomes, namely the Michigan Hand Questionnaire (MHQ) and 36-item Short Form Health Survey (SF-36), were measured at baseline (pre-injury) and 3 months, and return to work/leisure and level of adherence at 3 months.</p><p><strong>Results: </strong>Data from 32 participants (20 male, mean age 39.8 years, 61 repaired tendons) were analyzed. At 3 months post-injury, mean ROM was 83.5% and 73.8%, compared to the unaffected hand, for total active motion and Strickland-Glogovac ROM, respectively, and grip strength 68.4%. All MHQ scores were statistically significantly worse at 3 months compared to pre-injury (p ≤ 0.012), as were the physical role limitations and physical component summary scores of the SF-36 (p ≤ 0.023). All participants (100.0%) had returned to work by 3 months, and virtually all (96.6%) to leisure activities, although not always at pre-injury levels. The number of digits involved statistically significantly affected Strickland-Glogovac ROM (p ≤ 0.049), flexor deficit (p = 0.042) and SF-36 summary and total scores (p ≤ 0.049). The number of tendons involved statistically significantly affected flexor deficit (p = 0.042). Participant's adherence statistically significantly affected MHQ total score (p = 0.028).</p><p><strong>Conclusions: </strong>The use of patient-reported outcomes, in addition to clinician-reported outcomes, provided deeper insight into patients' perceptions of their recovery after flexor tendon injury.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hand function and quality of life with a 3D-printed prosthesis: A case report.","authors":"Regina Rossi, Gregory Chown","doi":"10.1016/j.jht.2024.12.004","DOIUrl":"https://doi.org/10.1016/j.jht.2024.12.004","url":null,"abstract":"<p><strong>Background: </strong>People throughout the world have amputations but cannot obtain prosthetic devices. 3D-printing can be a cost-effective tool to create prostheses.</p><p><strong>Purpose: </strong>The study's purpose is to examine the impact that a 3D-printed prosthetic hand has on function and quality of life.</p><p><strong>Study design: </strong>This case report collected data from a single subject.</p><p><strong>Methods: </strong>For function and quality of life, the Orthotics Prosthetics Users Surveys (OPUS) Upper Extremity Functional Status (UEFS) and the OPUS Health-Related Quality of Life Index (HRQOL) were completed before and after receiving a 3D-printed prosthetic hand.</p><p><strong>Results: </strong>The UEFS pre-test score was 31, while post-test was 50. This 19-point difference exceeds the minimal detectable change (MDC) of 14.8, denoting a positive change. The HRQOL pre-test score was 58 and the post-test was 61. Since the MDC for this survey is 7.4, there is no substantial improvement.</p><p><strong>Conclusions: </strong>Function improved for this participant by nearly two standard deviations, while quality of life was maintained. 3D-printing is a viable, adaptable, and cost-effective alternative that aided the participant's function. This technology in the clinic can meet unique client needs when considering financial limitations or multiple prostheses for growing children.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Harte, Lucia Ramsey, Lynn Wilson, Suzanne Martin
{"title":"Total active range of movement after treatment using a traction orthotic for extra-articular phalangeal fractures: A case series.","authors":"Daniel Harte, Lucia Ramsey, Lynn Wilson, Suzanne Martin","doi":"10.1016/j.jht.2025.01.005","DOIUrl":"https://doi.org/10.1016/j.jht.2025.01.005","url":null,"abstract":"<p><strong>Background: </strong>The use of traction orthoses for complex finger fractures is not a common intervention though some research purports its efficacy as an alternative treatment approach to surgery in some scenarios.</p><p><strong>Purpose: </strong>This study examined total active of range of movement (TAROM) outcomes achieved by patients on discharge from hand therapy after being treated using a traction orthotic following an extra-articular displaced proximal or middle phalangeal fracture.</p><p><strong>Study design: </strong>A retrospective, consecutive longitudinal case series.</p><p><strong>Methods: </strong>Data was collected on the time from injury to traction, duration of traction, injury location (hand, digit, phalanx), fracture classification, age, sex, hand dominance, number of therapy sessions (mobilization phase of rehabilitation), duration from injury to discharge from hand therapy and TAROM at discharge. TAROM outcomes are categorized using the criteria recommended by the American Society of Surgery of the Hand. Categorical variables are summarized using frequency and percentages. Continuous data is summarized as mean and standard deviation or median and interquartile range. Any potential correlations between TAROM and time from injury to discharge were analyzed using Pearson's correlation (two-tailed).</p><p><strong>Results: </strong>Twenty-three patients were referred for traction (14 male: nine female). Three people went on to have surgery and two patients were lost to follow-up. Mean TAROM was 230.9º (SD 22.6º) indicating a good outcome using the American Society of Surgery of the Hand criteria. Mean time from injury to discharge was 65.6 (SD 30.4) days. There was no correlation observed between time from injury to discharge and TAROM on discharge (r = -0.18, p = 0.48).</p><p><strong>Conclusions: </strong>Good and excellent TAROM was achieved following treatment using traction orthoses for extra-articular phalangeal fractures though further studies are necessary. Larger sample sizes will allow for more granular analysis of different fracture classifications.</p>","PeriodicalId":54814,"journal":{"name":"Journal of Hand Therapy","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}