Journal of Nutrition Health & Aging最新文献

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Function Impairment Screening Tool predicts eight-year mortality in older adults: Beijing Longitudinal Study of Aging 功能障碍筛查工具可预测老年人八年死亡率北京老龄化纵向研究
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-16 DOI: 10.1016/j.jnha.2024.100384
Xiaxia Li , Yiming Pan , Li Zhang , Yaxin Zhang , Zhe Tang , Lina Ma
{"title":"Function Impairment Screening Tool predicts eight-year mortality in older adults: Beijing Longitudinal Study of Aging","authors":"Xiaxia Li ,&nbsp;Yiming Pan ,&nbsp;Li Zhang ,&nbsp;Yaxin Zhang ,&nbsp;Zhe Tang ,&nbsp;Lina Ma","doi":"10.1016/j.jnha.2024.100384","DOIUrl":"10.1016/j.jnha.2024.100384","url":null,"abstract":"<div><h3>Purpose</h3><div>Function impairment is an early stage of disability in older adults and requires timely intervention. We have previously developed Function Impairment Screening Tool (FIST) based on the Delphi method, which has good reliability and validity, but the predictive effect is unknown. Therefore, we aimed to explore the role of FIST in predicting long-term mortality in community-dwelling older adults.</div></div><div><h3>Participants and methods</h3><div>Data were from the Beijing Longitudinal Study of Aging. A total of 1,833 older adults with 8 years of follow-up were included. Function impairment was assessed using FIST. Cox proportional hazards model was used to calculate the predictive effect of FIST on 8-year all-cause mortality.</div></div><div><h3>Results</h3><div>According to FIST, approximately half of the older adults had function impairment (47.6%). The prevalence of function impairment varied across populations. Logistic regression analysis showed that age, female, rural, poor health satisfaction, not drinking tea, and low Mini-Mental State Examination and intrinsic capacity score were associated with function impairment. Furthermore, function impairment was associated with poor physical function and high mortality. Cox analysis showed that FIST could predict 8-year mortality (hazard ratio [HR] = 3.26, 95% confidence interval [CI] 2.74–3.87), and this relationship persisted after adjusting for age, sex, area, marital status, live alone, educational level, smoking, drinking alcohol, and chronic diseases (HR = 1.79, 95% CI 1.45–2.17).</div></div><div><h3>Discussion</h3><div>FIST can predict 8-year mortality in community-dwelling older adults. More attention should be paid to older adults with function impairment and early intervention should be provided.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 12","pages":"Article 100384"},"PeriodicalIF":4.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protein source associated with risk of metabolic syndrome in adults with low and adequate protein intake: A prospective cohort study of middle-aged and older adults 蛋白质来源与蛋白质摄入量较低和充足的成年人患代谢综合征的风险有关:一项针对中老年人的前瞻性队列研究
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-16 DOI: 10.1016/j.jnha.2024.100393
Jieun Lyu , Joong-Yeon Lim , Yerim Han , Khuhee Na , Seungyoun Jung , Yoon Jung Park
{"title":"Protein source associated with risk of metabolic syndrome in adults with low and adequate protein intake: A prospective cohort study of middle-aged and older adults","authors":"Jieun Lyu ,&nbsp;Joong-Yeon Lim ,&nbsp;Yerim Han ,&nbsp;Khuhee Na ,&nbsp;Seungyoun Jung ,&nbsp;Yoon Jung Park","doi":"10.1016/j.jnha.2024.100393","DOIUrl":"10.1016/j.jnha.2024.100393","url":null,"abstract":"<div><h3>Objectives</h3><div>Metabolic syndrome is associated with an increased risk of diabetes, cardiovascular disease, and all-cause mortality. Some evidence suggests that the cardiometabolic health benefits of protein intake may vary by the source (animal or plant); however, the evidence is inconsistent. This study aimed to assess the risk of developing metabolic syndrome according to the protein source.</div></div><div><h3>Participants</h3><div>Among a total of 3,310 participants aged 40 years or older in the Ansan and Ansung population based prospective cohort, 1,543 incident cases of metabolic syndrome were identified between 2007 and 2018.</div></div><div><h3>Measurements</h3><div>Dietary intake was assessed using a validated food frequency questionnaire. Cox proportional hazards models were used to estimate the hazard ratios (HRs) and 95% confidence intervals (CIs) by quintile (Q), adjusting for demographics and health-related lifestyle factors.</div></div><div><h3>Results</h3><div>Higher intake of animal protein (HR<sub>quintile5 (Q5) vs quintile1 (Q1)</sub> [95% CIs]: 0.76 [0.59−0.96], P-trend <span><math><mo>≤</mo></math></span> 0.0307) and a higher relative intake of animal protein (HR<sub>Q5 vs.Q1</sub>: 0.78 [0.64−0.95], P-trend <span><math><mo>≤</mo></math></span> 0.0017) were associated with a significantly decreased risk of developing metabolic syndrome. In subgroup analyses, associations between the risk of metabolic syndrome and the relative intake of animal and plant protein differed according to whether the total protein intake was within the recommended nutrient intake (RNI). Specifically, significant associations were observed only among those with a total protein consumption below the RNI (HR<sub>Q5vs Q1</sub> [95% CIs]: 0.72 [0.56−0.93] for the relative intake of animal protein), but not among those consuming above the RNI. This association was more significant in women than in men.</div></div><div><h3>Conclusion</h3><div>A higher absolute and relative intake of animal protein were associated with a significantly decreased risk of metabolic syndrome, particularly among those who consumed less than the RNI of protein.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 12","pages":"Article 100393"},"PeriodicalIF":4.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142442018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between malnutrition risk and the prognosis of geriatric heart failure patients undergoing left ventricular assist device implantation 接受左心室辅助装置植入术的老年心力衰竭患者营养不良风险与预后之间的关系
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-15 DOI: 10.1016/j.jnha.2024.100382
Rui Shi , Zhenhan Li , Xinyue Duan , Jun Luo , Yuxiang Luo , Qingchen Wu , Dan Chen , Xin Tian , Hongtao Tie
{"title":"Association between malnutrition risk and the prognosis of geriatric heart failure patients undergoing left ventricular assist device implantation","authors":"Rui Shi ,&nbsp;Zhenhan Li ,&nbsp;Xinyue Duan ,&nbsp;Jun Luo ,&nbsp;Yuxiang Luo ,&nbsp;Qingchen Wu ,&nbsp;Dan Chen ,&nbsp;Xin Tian ,&nbsp;Hongtao Tie","doi":"10.1016/j.jnha.2024.100382","DOIUrl":"10.1016/j.jnha.2024.100382","url":null,"abstract":"<div><h3>Background</h3><div>Evidence regarding the association between malnutrition risk and the prognosis of geriatric heart failure (HF) patients undergoing left ventricular assist device (LVAD) implantation is lacking. Our study aims to investigate how malnutrition risk, assessed using the geriatric nutritional risk index (GNRI) values, relates to the outcomes of geriatric HF patients undergoing LVAD, using data from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) registry.</div></div><div><h3>Methods</h3><div>A retrospective analysis was conducted using data from INTERMACS registry. Patients aged 65 and above who received LVAD implantation between 2008 and 2017 were included. The GNRI was used to stratify patients into three groups: absence of risk (GNRI &gt; 98), mild risk (GNRI 92–98), and moderate to severe risk (GNRI &lt; 92). The primary outcome was long-term survival for up to four years following LVAD implantation.</div></div><div><h3>Results</h3><div>We included 5429 patients aged 65 and above undergoing LVADs. The malnutrition risk was presented in 75.8% of the patients before implantation, decreasing to 32.4% at 3 months, and 59.5% at 24 months post-implantation. Moderate-to-severe malnutrition risk, both pre-implant and 6 months post-implant, was associated with an increased risk of death (pre-implant: hazard ratio (HR): 1.25 [95% CI: 1.12–1.40], p &lt; 0.001; 6 months: HR: 2.36 [95% CI: 2.01–2.77], p &lt; 0.001). Mortality decreased with increasing pre-implant GNRI up to approximately 100 and 6-month post-implant GNRI up to 104. Patients with malnutrition risk also had an increased risk of infection, poor quality of life (QoL), and reduced functional exercise capacity after the LVAD implantation.</div></div><div><h3>Conclusions</h3><div>Malnutrition risk was highly prevalent in HF patients aged 65 and above undergoing LVADs implantation. The presence of malnutrition risk was associated with an increased risk of death, infection, poor quality of life, and reduced functional exercise capacity.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 12","pages":"Article 100382"},"PeriodicalIF":4.3,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor regarding “Comfort Feeding in Hospitalised People with Dementia: A Retrospective Study of Survival Following Comfort Feeding Recommendations” 致编辑的信,内容涉及 "住院痴呆症患者的舒适喂养:舒适喂养建议实施后存活率的回顾性研究
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-15 DOI: 10.1016/j.jnha.2024.100383
Rui He, Lingjia Xu
{"title":"Letter to the Editor regarding “Comfort Feeding in Hospitalised People with Dementia: A Retrospective Study of Survival Following Comfort Feeding Recommendations”","authors":"Rui He,&nbsp;Lingjia Xu","doi":"10.1016/j.jnha.2024.100383","DOIUrl":"10.1016/j.jnha.2024.100383","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 12","pages":"Article 100383"},"PeriodicalIF":4.3,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Limited predictive value of bioelectrical phase angle for the development of sarcopenia in older Europeans 生物电相位角对欧洲老年人患肌少症的预测价值有限
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-15 DOI: 10.1016/j.jnha.2024.100386
Małgorzata Pigłowska , Andrea Corsonello , Tomasz Kostka , Regina Roller-Wirnsberger , Gerhard Wirnsberger , Johan Ärnlöv , Axel C. Carlsson , Lisanne Tap , Francesco Mattace-Raso , Francesc Formiga , Rafael Moreno-González , Robert Kob , Cornel Sieber , Pedro Gil , Sara Lainez Martinez , Ronit Ben-Romano , Itshak Melzer , Paolo Fabbietti , Fabrizia Lattanzio , Agnieszka Guligowska
{"title":"Limited predictive value of bioelectrical phase angle for the development of sarcopenia in older Europeans","authors":"Małgorzata Pigłowska ,&nbsp;Andrea Corsonello ,&nbsp;Tomasz Kostka ,&nbsp;Regina Roller-Wirnsberger ,&nbsp;Gerhard Wirnsberger ,&nbsp;Johan Ärnlöv ,&nbsp;Axel C. Carlsson ,&nbsp;Lisanne Tap ,&nbsp;Francesco Mattace-Raso ,&nbsp;Francesc Formiga ,&nbsp;Rafael Moreno-González ,&nbsp;Robert Kob ,&nbsp;Cornel Sieber ,&nbsp;Pedro Gil ,&nbsp;Sara Lainez Martinez ,&nbsp;Ronit Ben-Romano ,&nbsp;Itshak Melzer ,&nbsp;Paolo Fabbietti ,&nbsp;Fabrizia Lattanzio ,&nbsp;Agnieszka Guligowska","doi":"10.1016/j.jnha.2024.100386","DOIUrl":"10.1016/j.jnha.2024.100386","url":null,"abstract":"<div><h3>Background</h3><div>Despite the emerging interest in phase angle (PhA), a non-invasive marker of cell hydration and nutritional status, no previous study has reported the prospective association between PhA and incident sarcopenia. Therefore, the aim of our study was to evaluate the association of baseline PhA in older subjects without sarcopenia with the development of new sarcopenia as outcome.</div></div><div><h3>Methods</h3><div>Six-hundred ninety-six subjects without sarcopenia aged ≥75 years enrolled in an international multicenter observational study were included. Sarcopenia was assessed according to the revised EWGSOP2 criteria at baseline and in follow-up visits at 12 and 24 months. Muscle strength was assessed through the handgrip strength test using a hydraulic grip strength dynamometer, muscle mass was assessed by bioimpedance analysis (BIA) and appendicular skeletal muscle mass (ASMM) was estimated. Physical performance was assessed by Short Physical Performance Battery (SPPB).</div></div><div><h3>Results</h3><div>Participants who developed sarcopenia were older, less educated, had higher prevalence of osteoporosis, and lower baseline cognitive function, SPPB, handgrip strength and ASMM than those without sarcopenia. Baseline PhA was significantly lower in subjects developing sarcopenia. Nevertheless, after adjusting for all potential covariates including baseline components of sarcopenia in multiple logistic regression, neither PhA as continuous variable nor different levels of PhA were any more significant predictors of sarcopenia.</div></div><div><h3>Conclusions</h3><div>As an indicator of cells function, PhA could be a potential useful early marker in identifying older people at risk of developing sarcopenia but its practical applicability remains uncertain with the present data.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 12","pages":"Article 100386"},"PeriodicalIF":4.3,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corrigendum to “The association between anemia and all-cause mortality among Chinese older people: The evidence from CHARLS” [The Journal of nutrition, health and aging 28 (2024) 100281] 中国老年人贫血与全因死亡率的关系:来自 CHARLS 的证据》[《营养、健康与老龄化杂志》28 (2024) 100281]。
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-01 DOI: 10.1016/j.jnha.2024.100380
Xiao-Ming Zhang , Lie-E Li , Cong-Hua Wang , Qing-Li Dou , Yun-Zhi Yang
{"title":"Corrigendum to “The association between anemia and all-cause mortality among Chinese older people: The evidence from CHARLS” [The Journal of nutrition, health and aging 28 (2024) 100281]","authors":"Xiao-Ming Zhang ,&nbsp;Lie-E Li ,&nbsp;Cong-Hua Wang ,&nbsp;Qing-Li Dou ,&nbsp;Yun-Zhi Yang","doi":"10.1016/j.jnha.2024.100380","DOIUrl":"10.1016/j.jnha.2024.100380","url":null,"abstract":"","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100380"},"PeriodicalIF":4.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142376325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diet quality in U.S. adults eating in senior and community centers: NHANES 2009-2018 在老年中心和社区中心就餐的美国成年人的饮食质量:Nhanes 2009-2018。
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-01 DOI: 10.1016/j.jnha.2024.100379
Maximilian Andreas Storz , Alvaro Luis Ronco
{"title":"Diet quality in U.S. adults eating in senior and community centers: NHANES 2009-2018","authors":"Maximilian Andreas Storz ,&nbsp;Alvaro Luis Ronco","doi":"10.1016/j.jnha.2024.100379","DOIUrl":"10.1016/j.jnha.2024.100379","url":null,"abstract":"<div><h3>Background</h3><div>With advancing age, the worsening of cognitive and physical disabilities may lead older adults to seek help in their daily living activities. Community/senior centers support older adults during aging, offering a wide variety of services, including meal programs. Using data from the National Health and Nutrition Examination Surveys (2009–2018), we aimed to examine whether community/senior center meal programs were associated with an improved nutritional exposure in U.S. adults aged 60 years or older.</div></div><div><h3>Methods</h3><div>Nutrient exposure and nutrient-based dietary indexes, including the Diet Quality Score (DQS) and the Food Nutrient Index (FNI) were compared between those eating meals at community/senior centers and the general population. Nutrient intakes were contrasted to the daily nutritional goals from the Dietary Guidelines for Americans.</div></div><div><h3>Results</h3><div>This study included 6261 participants aged ≥60 years, thereof <em>n</em> = 421 reporting community/senior center meals. The latter were predominantly female and almost 45% were widowed or divorced. Eating at community/senior centers did not result in a better diet quality in crude analyses. After adjustment for potential sociodemographic confounders as well as alcohol, smoking and energy intake, however, sex-specific differences emerged, revealing significantly higher FNI scores in males eating at community/senior centers (adjusted FNI predictions: 61.71 [CI:58.55–64.88] vs 57.64 [CI:56.86−58.41] points).</div></div><div><h3>Conclusions</h3><div>Eating at community/senior centers was associated with an improved nutrient exposure in older men, whereas no better diet quality was found in women. Community/senior centers may play a pivotal role when it comes to the diet quality of a particularly vulnerable group of the population.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 11","pages":"Article 100379"},"PeriodicalIF":4.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-effectiveness of protein-rich meals and snacks for increasing protein intake in older adults 增加老年人蛋白质摄入量的富含蛋白质的正餐和点心的成本效益
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100381
P. Rautakallio-Järvinen , S. Kunvik , M. Laaksonen , L. Fogelholm , I. Nykänen , U. Schwab
{"title":"Cost-effectiveness of protein-rich meals and snacks for increasing protein intake in older adults","authors":"P. Rautakallio-Järvinen ,&nbsp;S. Kunvik ,&nbsp;M. Laaksonen ,&nbsp;L. Fogelholm ,&nbsp;I. Nykänen ,&nbsp;U. Schwab","doi":"10.1016/j.jnha.2024.100381","DOIUrl":"10.1016/j.jnha.2024.100381","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the cost-effectiveness of protein-rich meals and snacks for increasing protein intake in home-dwelling older adults.</div></div><div><h3>Design</h3><div>Cost effectiveness analysis from a randomized controlled trial, the Power Meals study.</div></div><div><h3>Setting</h3><div>Participants were randomized into one of three groups for eight weeks: a protein-rich meal, snack and bread (Protein), a regular meal (Normal) and a control group without meal service (Control).</div></div><div><h3>Participants</h3><div>Home-dwelling home care clients, caregivers and care recipients aged ≥65 years (n = 65).</div></div><div><h3>Measurements</h3><div>Protein intake was assessed by a three-day food diary at the end of the study. Cost for the daily diet was estimated by using Finnish grocery store databases and the prices of the food service. The cost-effectiveness was assessed by an incremental cost-effectiveness ratio (ICER).</div></div><div><h3>Results</h3><div>Costs for the daily diet in the Protein (8.35 €/d) and the Normal (7.94 €/d) groups were significantly higher than in the control group (5.65 €/d) (p &lt; 0.001). Incremental cost-effectiveness analysis showed that increasing protein intake was cost-effective in the Protein group as incremental cost-effectiveness ratio was 8.11 in the Protein, 8.72 in the Normal and 6.45 in the Control group.</div></div><div><h3>Conclusions</h3><div>Including protein rich meals and snacks in a diet increases protein intake in home-dwelling older adults cost-effectively.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 11","pages":"Article 100381"},"PeriodicalIF":4.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of ultra-processed food intake with severe non-alcoholic fatty liver disease: a prospective study of 143073 UK Biobank participants 超加工食品摄入量与严重非酒精性脂肪肝的关系:对 143073 名英国生物数据库参与者的前瞻性研究
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100352
Yi-Feng Zhang , Wanning Qiao , Jinhong Zhuang , Hanxiao Feng , Zhilan Zhang , Yang Zhang
{"title":"Association of ultra-processed food intake with severe non-alcoholic fatty liver disease: a prospective study of 143073 UK Biobank participants","authors":"Yi-Feng Zhang ,&nbsp;Wanning Qiao ,&nbsp;Jinhong Zhuang ,&nbsp;Hanxiao Feng ,&nbsp;Zhilan Zhang ,&nbsp;Yang Zhang","doi":"10.1016/j.jnha.2024.100352","DOIUrl":"10.1016/j.jnha.2024.100352","url":null,"abstract":"<div><h3>Background</h3><div>Previous studies indicate a link between non-alcoholic fatty liver disease (NAFLD) and unhealthy dietary patterns or nutrient intake. However, it remains unclear whether ultra-processed foods (UPF) contribute to an increased risk of NAFLD. This study aimed to explore how ultra-processed food consumption correlates with severe NAFLD using the UK Biobank data.</div></div><div><h3>Methods</h3><div>This prospective cohort study included 143,073 participants from the UK Biobank. UPF consumption levels were determined using the NOVA classification and quantified from 24-h dietary recall data. The association between UPF consumption and severe NAFLD (hospitalization or death) was initially examined using Cox proportional hazards models with intake quartiles. Nonlinear associations were investigated using penalized cubic splines fitted in the Cox proportional hazards models. Adjustments were made for general characteristics, sociodemographic factors, body mass index (BMI), and lifestyle.</div></div><div><h3>Results</h3><div>Throughout the median follow-up period of 10.5 years, 1,445 participants developed severe NAFLD. The adjusted models indicated a significant increase in severe NAFLD risk in higher UPF intake groups compared to the lowest quartile (HR: 1.26 [95% CI: 1.11–1.43]). Subgroup analysis revealed that individuals with a BMI of 25 or higher were at greater risk in the highest quartile of UPF consumption. Sensitivity analyses yielded results consistent with these findings.</div></div><div><h3>Conclusion</h3><div>Higher consumption of UPF is associated with an increased risk of severe NAFLD. Reducing the intake of UPF can be a potential approach to lower the risk of NAFLD.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":"28 10","pages":"Article 100352"},"PeriodicalIF":4.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of allostatic load with functional disability in the China Health and Retirement Longitudinal Study 中国健康与退休纵向研究中异位负荷与功能障碍的关系
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100367
Wanyu Zhao , Yanjun Si , Xueqin Li , Yunli Zhao , Shuli Jia , Birong Dong
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