Journal of Nutrition Health & Aging最新文献

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Diet quality in U.S. adults eating in senior and community centers: NHANES 2009-2018 在老年中心和社区中心就餐的美国成年人的饮食质量:Nhanes 2009-2018。
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-10-01 DOI: 10.1016/j.jnha.2024.100379
{"title":"Diet quality in U.S. adults eating in senior and community centers: NHANES 2009-2018","authors":"","doi":"10.1016/j.jnha.2024.100379","DOIUrl":"10.1016/j.jnha.2024.100379","url":null,"abstract":"<div><h3>Background</h3><div>With advancing age, the worsening of cognitive and physical disabilities may lead older adults to seek help in their daily living activities. Community/senior centers support older adults during aging, offering a wide variety of services, including meal programs. Using data from the National Health and Nutrition Examination Surveys (2009–2018), we aimed to examine whether community/senior center meal programs were associated with an improved nutritional exposure in U.S. adults aged 60 years or older.</div></div><div><h3>Methods</h3><div>Nutrient exposure and nutrient-based dietary indexes, including the Diet Quality Score (DQS) and the Food Nutrient Index (FNI) were compared between those eating meals at community/senior centers and the general population. Nutrient intakes were contrasted to the daily nutritional goals from the Dietary Guidelines for Americans.</div></div><div><h3>Results</h3><div>This study included 6261 participants aged ≥60 years, thereof <em>n</em> = 421 reporting community/senior center meals. The latter were predominantly female and almost 45% were widowed or divorced. Eating at community/senior centers did not result in a better diet quality in crude analyses. After adjustment for potential sociodemographic confounders as well as alcohol, smoking and energy intake, however, sex-specific differences emerged, revealing significantly higher FNI scores in males eating at community/senior centers (adjusted FNI predictions: 61.71 [CI:58.55–64.88] vs 57.64 [CI:56.86−58.41] points).</div></div><div><h3>Conclusions</h3><div>Eating at community/senior centers was associated with an improved nutrient exposure in older men, whereas no better diet quality was found in women. Community/senior centers may play a pivotal role when it comes to the diet quality of a particularly vulnerable group of the population.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost-effectiveness of protein-rich meals and snacks for increasing protein intake in older adults 增加老年人蛋白质摄入量的富含蛋白质的正餐和点心的成本效益
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100381
{"title":"Cost-effectiveness of protein-rich meals and snacks for increasing protein intake in older adults","authors":"","doi":"10.1016/j.jnha.2024.100381","DOIUrl":"10.1016/j.jnha.2024.100381","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the cost-effectiveness of protein-rich meals and snacks for increasing protein intake in home-dwelling older adults.</div></div><div><h3>Design</h3><div>Cost effectiveness analysis from a randomized controlled trial, the Power Meals study.</div></div><div><h3>Setting</h3><div>Participants were randomized into one of three groups for eight weeks: a protein-rich meal, snack and bread (Protein), a regular meal (Normal) and a control group without meal service (Control).</div></div><div><h3>Participants</h3><div>Home-dwelling home care clients, caregivers and care recipients aged ≥65 years (n = 65).</div></div><div><h3>Measurements</h3><div>Protein intake was assessed by a three-day food diary at the end of the study. Cost for the daily diet was estimated by using Finnish grocery store databases and the prices of the food service. The cost-effectiveness was assessed by an incremental cost-effectiveness ratio (ICER).</div></div><div><h3>Results</h3><div>Costs for the daily diet in the Protein (8.35 €/d) and the Normal (7.94 €/d) groups were significantly higher than in the control group (5.65 €/d) (p &lt; 0.001). Incremental cost-effectiveness analysis showed that increasing protein intake was cost-effective in the Protein group as incremental cost-effectiveness ratio was 8.11 in the Protein, 8.72 in the Normal and 6.45 in the Control group.</div></div><div><h3>Conclusions</h3><div>Including protein rich meals and snacks in a diet increases protein intake in home-dwelling older adults cost-effectively.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of ultra-processed food intake with severe non-alcoholic fatty liver disease: a prospective study of 143073 UK Biobank participants 超加工食品摄入量与严重非酒精性脂肪肝的关系:对 143073 名英国生物数据库参与者的前瞻性研究
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100352
{"title":"Association of ultra-processed food intake with severe non-alcoholic fatty liver disease: a prospective study of 143073 UK Biobank participants","authors":"","doi":"10.1016/j.jnha.2024.100352","DOIUrl":"10.1016/j.jnha.2024.100352","url":null,"abstract":"<div><h3>Background</h3><div>Previous studies indicate a link between non-alcoholic fatty liver disease (NAFLD) and unhealthy dietary patterns or nutrient intake. However, it remains unclear whether ultra-processed foods (UPF) contribute to an increased risk of NAFLD. This study aimed to explore how ultra-processed food consumption correlates with severe NAFLD using the UK Biobank data.</div></div><div><h3>Methods</h3><div>This prospective cohort study included 143,073 participants from the UK Biobank. UPF consumption levels were determined using the NOVA classification and quantified from 24-h dietary recall data. The association between UPF consumption and severe NAFLD (hospitalization or death) was initially examined using Cox proportional hazards models with intake quartiles. Nonlinear associations were investigated using penalized cubic splines fitted in the Cox proportional hazards models. Adjustments were made for general characteristics, sociodemographic factors, body mass index (BMI), and lifestyle.</div></div><div><h3>Results</h3><div>Throughout the median follow-up period of 10.5 years, 1,445 participants developed severe NAFLD. The adjusted models indicated a significant increase in severe NAFLD risk in higher UPF intake groups compared to the lowest quartile (HR: 1.26 [95% CI: 1.11–1.43]). Subgroup analysis revealed that individuals with a BMI of 25 or higher were at greater risk in the highest quartile of UPF consumption. Sensitivity analyses yielded results consistent with these findings.</div></div><div><h3>Conclusion</h3><div>Higher consumption of UPF is associated with an increased risk of severe NAFLD. Reducing the intake of UPF can be a potential approach to lower the risk of NAFLD.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of allostatic load with functional disability in the China Health and Retirement Longitudinal Study 中国健康与退休纵向研究中异位负荷与功能障碍的关系
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100367
{"title":"Association of allostatic load with functional disability in the China Health and Retirement Longitudinal Study","authors":"","doi":"10.1016/j.jnha.2024.100367","DOIUrl":"10.1016/j.jnha.2024.100367","url":null,"abstract":"<div><h3>Objectives</h3><div>Allostatic load (AL) is an index that manifests as cumulative wear and tear on multiple physiological systems resulting from repeated adaptation to stressors throughout the life course. Higher AL was found to be associated with increased risk of adverse health outcomes, but studies on functional disability among large Chinese older population were limited. We aimed to investigate the associations of AL with functional disability among Chinese older adults.</div></div><div><h3>Research design and methods</h3><div>This prospective cohort study included 5880 older adults who were at least 50 years old and participated in the CHARLS at baseline (2011 wave), with 3 follow-ups (2013, 2015 and 2018 waves). We selected 11 biomarkers from 4 physiological systems to construct AL. AL score was classified into three categories based on tertiles: 0–1 (low burden), 2–3 (medium burden) and 4–11 (high burden). Functional disability was assessed by activities of daily living (ADL) and instrumental activities of daily living (IADL). Multivariable logistic regression models examined the association between baseline AL, transitions of AL burden and incidence of functional disability.</div></div><div><h3>Results</h3><div>In cross-sectional analyses, medium and high AL burden were associated with an increased prevalence of ADL disability, while association was only significant between high AL burden and IADL disability. During the 7-year follow-up, 1102 and 1777 participants incident ADL disability and IADL disability, respectively. Those with medium and high AL burden had an increased risk of new-onset ADL disability than those with low AL burden (“medium”: OR = 1.25, 95%CI = 1.01, 1.55; “high”: OR = 1.69, 95%CI = 1.32, 2.18). As for IADL disability, association was only significant in “high” group (OR = 1.50, 95% CI = 1.24, 1.83). We also found keep medium/high AL burden in 2011 and 2015 was associated with new-onset ADL (OR = 2.27, 95%CI = 1.50, 3.44) and IADL disability (OR = 1.51, 95%CI = 1.11, 2.05) in 2018.</div></div><div><h3>Conclusion</h3><div>These results show that higher AL predicts functional disability among Chinese older adults. Monitoring AL and paying close attention to those with medium/high AL burden may aid prevention of adverse health outcomes, thus giving a healthier ageing experience to a large proportion of the population.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biological sex as a tailoring variable for exercise prescription in hospitalized older adults 将生理性别作为住院老年人运动处方的定制变量
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-27 DOI: 10.1016/j.jnha.2024.100377
{"title":"Biological sex as a tailoring variable for exercise prescription in hospitalized older adults","authors":"","doi":"10.1016/j.jnha.2024.100377","DOIUrl":"10.1016/j.jnha.2024.100377","url":null,"abstract":"<div><h3>Background</h3><div>Sex-based differences in the clinical presentation and outcomes are well-established in patients hospitalized for geriatric syndromes. We aimed to investigate sex differences in response to in-hospital exercise on function, strength, cognition, and quality of life in acute care admissions.</div></div><div><h3>Methods</h3><div>570 patients (mean age 87 years, 298 females [52.3%]) admitted to acute care for elderly units were randomized to multicomponent exercise emphasizing progressive resistance training or usual care. Functional assessments included Short Physical Performance Battery (SPPB), grip strength, Mini-Mental State Examination (MMSE), and health-related quality of life (EQ-VAS).</div></div><div><h3>Results</h3><div>Exercising females showed more significant SPPB improvements than males (between-group difference 1.48 points, p = 0.027), exceeding the minimal clinically significant difference. While female participants significantly increased handgrip strength and male patients improved cognition after in-hospital exercise compared to the control group (all p &lt; 0.001), no sex differences occurred.</div></div><div><h3>Conclusions</h3><div>Females demonstrate more excellent physical function improvements compared to male older patients. Findings highlight the importance of tailored exercise incorporating patient factors like biological sex in geriatric medicine.</div></div><div><h3>Trial registration</h3><div>NCT04600453.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142327184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of an older adult Nutrition Equity Index (NEI) and association with the Healthy Eating Index (HEI) in older Black and White U.S. adults 美国黑人和白人老年人营养公平指数(NEI)的制定及其与健康饮食指数(HEI)的联系
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-25 DOI: 10.1016/j.jnha.2024.100343
{"title":"Development of an older adult Nutrition Equity Index (NEI) and association with the Healthy Eating Index (HEI) in older Black and White U.S. adults","authors":"","doi":"10.1016/j.jnha.2024.100343","DOIUrl":"10.1016/j.jnha.2024.100343","url":null,"abstract":"<div><h3>Objectives</h3><div>We developed a novel measure for older U.S. adults called the Nutrition Equity Index (NEI), which includes functional ability. We compared both the NEI and food insufficiency with Healthy Eating Index (HEI) scores.</div></div><div><h3>Design</h3><div>The Health, Aging, and Body Composition Study is a prospective, longitudinal cohort of Medicare-eligible, community-dwelling Black and White men and women.</div></div><div><h3>Setting</h3><div>Pittsburgh, PA and Memphis, TN.</div></div><div><h3>Participants</h3><div>Participants (N = 2468, aged 74.7 ± 2.9 years) had baseline (1997−98) and 1-year follow-up NEI data; and 1 year follow-up for food insufficiency, key covariates, and the HEI (diet quality measure) from a 108-item interviewer-administered food frequency questionnaire.</div></div><div><h3>Measurements</h3><div>Food insufficiency was defined from a modified validated question on ample food amount/variety from the U.S. Department of Agriculture. NEI was constructed from 8 questions in three subdomains: food insecurity (food insufficiency, hunger, anxiety about limited food, limited money for food), food access (groceries), and food acquisition (difficulty shopping, preparing meals, carrying groceries). Final NEI categories were low nutrition equity (0), moderate nutrition equity (1), and high nutrition equity (2). Multivariable linear regression compared both NEI and food insufficiency with HEI, adjusted for sociodemographic, lifestyle and comorbidity factors.</div></div><div><h3>Results</h3><div>Of participants, 13.5% had food insufficiency, 12.1% had low NEI, and 32.5% had moderate NEI. Participants with food insufficiency (vs. food sufficiency) or low NEI (vs. high NEI) were more likely to be Black and have &lt; high school education (both p &lt; 0.0001). In minimally adjusted models, food insufficiency was associated with 2.2 point lower HEI score (p = 0.001), low NEI with 2.6 point lower HEI score (p = 0.001), and moderate NEI with 1.0 point lower HEI score (p &lt; 0.05). Adjusting for race attenuated NEI associations with HEI to non-significance. After multivariable adjustment, food insufficiency was associated with 1.5 point lower HEI score (p = 0.03).</div></div><div><h3>Conclusion</h3><div>Food insufficiency was associated with lower dietary quality in this sample of older Black and White U.S. adults. NEI performed similarly to food insufficiency for HEI associations prior to multivariable adjustment and identified more older adults with nutrition inequity, who may be at risk for poor health outcomes.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142320115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intake of vegetables and fruits at midlife and the risk of physical frailty in later life 中年时蔬菜和水果的摄入量与晚年身体虚弱的风险
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-23 DOI: 10.1016/j.jnha.2024.100374
{"title":"Intake of vegetables and fruits at midlife and the risk of physical frailty in later life","authors":"","doi":"10.1016/j.jnha.2024.100374","DOIUrl":"10.1016/j.jnha.2024.100374","url":null,"abstract":"<div><h3>Objectives</h3><div>Our study evaluated the independent and overall associations of vegetable and fruit consumption at midlife with the likelihood of physical frailty in later life. We also investigated whether specific nutrients in these foods could have accounted for these associations, if present.</div></div><div><h3>Design</h3><div>Prospective cohort study.</div></div><div><h3>Setting</h3><div>A population-based cohort of Chinese adults followed over a period of 20 years in Singapore.</div></div><div><h3>Participants</h3><div>We used data from 11,959 subjects who participated in the baseline (1993–1998) and follow-up 3 (2014–2017) interviews of the Singapore Chinese Health Study.</div></div><div><h3>Measurements</h3><div>At baseline, dietary intake was evaluated using a validated food frequency questionnaire. During the follow-up 3 visits, physical frailty was assessed using a modified Cardiovascular Health Study phenotype that included weakness, slowness, exhaustion and weight loss. Multivariable logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) for the associations with physical frailty.</div></div><div><h3>Results</h3><div>Participants had mean ages of 52 years at baseline, and 72 years at follow-up 3. Baseline intake of vegetables, but not of fruits, showed a dose-dependent inverse relationship with physical frailty at follow-up 3 (<em>P</em><sub>trend</sub> = 0.001). Compared to participants in the lowest quintile of vegetable intake, those in the highest quintile had reduced odds of frailty [OR (95% CI): 0.73 (0.60−0.89)]. Among the components of physical frailty, vegetable intake had the strongest inverse association with weakness defined by handgrip strength [OR (95% CI) between extreme quintiles: 0.62 (0.52−0.73); <em>P</em><sub>trend</sub> &lt; 0.001]. In models that were individually adjusted for nutrients, the vegetable-frailty association was attenuated and no longer statistically significant after adjusting for the intake of β-carotene, lutein, folate, α-carotene, and isothiocyanates.</div></div><div><h3>Conclusion</h3><div>: Increased midlife intake of vegetables was associated with reduced odds of physical frailty in later life, and the intake of β-carotene, lutein, folate, α-carotene, and isothiocyanates could have accounted for this association.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004615/pdfft?md5=915847ed1bb83a30ebe2bc858bf5dc22&pid=1-s2.0-S1279770724004615-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender-specific capacity of insulin resistance proxies to predict functional decline in older adults 胰岛素抵抗代用指标预测老年人功能衰退的能力因性别而异
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-23 DOI: 10.1016/j.jnha.2024.100376
{"title":"Gender-specific capacity of insulin resistance proxies to predict functional decline in older adults","authors":"","doi":"10.1016/j.jnha.2024.100376","DOIUrl":"10.1016/j.jnha.2024.100376","url":null,"abstract":"<div><h3>Objectives</h3><div>Insulin resistance determined by Homeostasis Model of Insulin Resistance (HOMA-IR) has been associated with functional decline in non-diabetic older subjects. However, insulin is not routinely assessed. The study evaluated the predictive value of non-insulin-dependent IR surrogates on functional decline in non-diabetic older men and women.</div></div><div><h3>Design and participants</h3><div>Prospective cohort study over 5 years. The study included 615 older participants from the Toledo Study of Healthy Aging.</div></div><div><h3>Methods</h3><div>Frailty was assessed by the Frailty Trait Scale-5 (FTS-5) at baseline and after 5 years follow-up. 193 subjects experienced functional decline (2.5-point reduction in the FTS-5 score). Multivariate regression models analysed the effect of five described IR surrogates on functional decline considering potential confounders.</div></div><div><h3>Results</h3><div>Among evaluated IR proxies, triglyceride glucose-body mass index (TyG-BMI) and HOMA-IR were significantly associated with an increased risk of functional decline (odd ratio (95% confidence interval) TyG-BMI: 1.16 (1.05, 1.28), p = 0.0035 and HOMA-IR: 1.59 (1.15, 2.21), p = 0.0056) among all participants. When stratified by gender, HOMA-IR was related to functional decline in men [2.02 (1.13, 3.59), p = 0.0173] and TyG-BMI in women [1.19 (1.05, 1.35), p = 0.0057].</div></div><div><h3>Conclusions</h3><div>Only TyG-BMI index mimics the predictive capacity of insulin-based IR marker. The predictive ability of IR indexes is gender-specific, being TyG-BMI the only index able to predict functional decline in women and HOMA-IR in men.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1279770724004639/pdfft?md5=c552ecedf2a0505333cd34e206c0cdd5&pid=1-s2.0-S1279770724004639-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteosarcopenia predicts greater risk of functional disability than sarcopenia: a longitudinal analysis of FraDySMex cohort study 骨肉疏松症比肌肉疏松症更容易导致功能性残疾:FraDySMex 队列研究的纵向分析。
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-21 DOI: 10.1016/j.jnha.2024.100368
{"title":"Osteosarcopenia predicts greater risk of functional disability than sarcopenia: a longitudinal analysis of FraDySMex cohort study","authors":"","doi":"10.1016/j.jnha.2024.100368","DOIUrl":"10.1016/j.jnha.2024.100368","url":null,"abstract":"<div><h3>Objectives</h3><div>Aging involves significant changes in body composition, marked by declines in muscle mass and bone mineral density alongside an increase in fat mass. Sarcopenia is characterized by low strength and muscle mass, and osteosarcopenia is the coexistence of sarcopenia and osteopenia/osteoporosis. Physiologically, there is a crosstalk between muscle and bone tissues mediated by several pathways. Both, sarcopenia and osteosarcopenia, have been related with adverse outcomes such as functional disability. However, there is a lack of longitudinal studies. Therefore, this study aimed to assess whether sarcopenia and osteosarcopenia phenotypes increased the risk of functional disability in a longitudinal cohort of community-dwelling adults.</div></div><div><h3>Design</h3><div>This study constitutes a secondary longitudinal analysis of data derived from the prospective cohort FraDySMex (Frailty, Dynapenia, and Sarcopenia in Mexican adults).</div></div><div><h3>Setting and participants</h3><div>FraDySMex is conducted in community-dwelling adults aged 50 years or older living in Mexico City. Data from 2014 to 2015 was considered as baseline evaluation, and the 2019 wave was the follow-up evaluation. Individuals with complete baseline and follow-up evaluations were included in the analysis.</div></div><div><h3>Measurements</h3><div>Sarcopenia diagnosis adhered to the FNIH criteria, while osteopenia/osteoporosis classification followed WHO guidelines. Osteosarcopenia was defined as the concurrent presence of sarcopenia and osteopenia/osteoporosis. Functional disability was identified by the Lawton Instrumental Activities of Daily Living (IADL) Scale. Adjusted mixed-effects logistic regression models were estimated to evaluate the effect of body composition phenotype on the risk of functional disability.</div></div><div><h3>Results</h3><div>The final sample included 320 adults with complete longitudinal data. The majority of were women (83.4%) and had 7–12 years of education (48.4%). At the baseline evaluation, 50.9% aged 50–70. The osteosarcopenia phenotype was associated with a higher risk of functional disability (OR: 2.17, p = 0.042) compared with the no osteopenia/sarcopenia group. Conversely, sarcopenia (OR: 1.50, p = 0.448) and osteopenia/osteoporosis (OR: 1.50, p = 0.185) phenotypes were not associated with functional disability.</div></div><div><h3>Conclusions</h3><div>Our study underscores that osteosarcopenia significantly increased the risk of functional disability, particularly in terms of Instrumental Activities of Daily Living (IADL). These results emphasize the importance of screening for sarcopenia, osteopenia/osteoporosis, and osteosarcopenia across various clinical settings. Early detection and intervention hold promise for averting functional disability and mitigating associated adverse outcomes in adults.</div></div>","PeriodicalId":54778,"journal":{"name":"Journal of Nutrition Health & Aging","volume":null,"pages":null},"PeriodicalIF":4.3,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S127977072400455X/pdfft?md5=886f20e9acb2a732ef2178384db5d845&pid=1-s2.0-S127977072400455X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142301259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing the role of social work in addressing social frailty and diet quality among older adults 加强社会工作在解决老年人社会脆弱性和饮食质量方面的作用。
IF 4.3 3区 医学
Journal of Nutrition Health & Aging Pub Date : 2024-09-21 DOI: 10.1016/j.jnha.2024.100375
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