{"title":"The value of LAR and IL-6 in early diagnosis and prognostic assessment of severe acute pancreatitis","authors":"Lin Xu , Meng Lin , Chao Liu , Guochao Zhu","doi":"10.1016/j.nupar.2025.04.002","DOIUrl":"10.1016/j.nupar.2025.04.002","url":null,"abstract":"<div><div>To analyze the clinical value of lactate dehydrogenase to albumin ratio (LAR) and interleukin-6 (IL-6) in the early diagnosis and prognostic assessment of severe acute pancreatitis (SAP). A retrospective study was conducted on 98 cases of acute pancreatitis patients. These patients were divided into two groups based on the severity of their condition: non-SAP group (<em>n</em> <!-->=<!--> <!-->68) and SAP group (<em>n</em> <!-->=<!--> <!-->30). Spearman correlation analysis was utilized to investigate the correlation of LAR and IL-6 with the bedside index for severity in acute pancreatitis (BISAP). Patients in the SAP group exhibited significantly higher LAR values and IL-6 levels compared to those in the non-SAP group (<em>P</em> <!--><<!--> <!-->0.05). The APR and IL-6 of SAP patients were significantly positively correlated with BISAP scores (R<!--> <!-->=<!--> <!-->0.758, <em>P</em> <!--><<!--> <!-->0.001) (R<!--> <!-->=<!--> <!-->0.660, <em>P</em> <!--><<!--> <!-->0.001). The diagnostic AUC of LAR and IL-6 for SAP were 0.742 (<em>P</em> <!--><<!--> <!-->0.001) and 0.749 (<em>P</em> <!--><<!--> <!-->0.001), respectively. The Logistic regression analysis demonstrated that LAR and IL-6 were independent risk factors for SAP (<em>P</em> <!--><<!--> <!-->0.05). The levels of LAR and IL-6 in the death subgroup were significantly higher than those in the survival subgroup (<em>P</em> <!--><<!--> <!-->0.05). The diagnostic AUC of LAR and IL-6 for poor prognosis of SAP were 0.971 (<em>P</em> <!--><<!--> <!-->0.001) and 0.713 (<em>P</em> <!-->=<!--> <!-->0.055), respectively. LAR was an independent risk factor for poor prognosis in SAP patients (<em>P</em> <!--><<!--> <!-->0.05). Patients with SAP may exhibit abnormally elevated levels of LAR and IL-6. LAR and IL-6 are closely associated with the severity of the patient's condition, which can be applied in the diagnosis of SAP.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Pages 142-148"},"PeriodicalIF":0.5,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L’éditorial de la présidente de la SNFCM","authors":"Francisca Joly","doi":"10.1016/j.nupar.2025.04.001","DOIUrl":"10.1016/j.nupar.2025.04.001","url":null,"abstract":"","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Page 87"},"PeriodicalIF":0.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wissal Zkhiri , Morad Guennouni , Aïcha Bourrahouat , Nysrine Mannani , Imane Ait Sab , Adil Ait Rami , Khadija Krati , Brahim Admou
{"title":"The prevalence of non-celiac gluten sensitivity in the general population: Systematic review and meta-analysis","authors":"Wissal Zkhiri , Morad Guennouni , Aïcha Bourrahouat , Nysrine Mannani , Imane Ait Sab , Adil Ait Rami , Khadija Krati , Brahim Admou","doi":"10.1016/j.nupar.2025.03.001","DOIUrl":"10.1016/j.nupar.2025.03.001","url":null,"abstract":"<div><h3>Objective</h3><div>This systematic review and meta-analysis aimed to determine the overall prevalence of non-celiac gluten sensitivity (NCGS) in the general population.</div></div><div><h3>Methods</h3><div>We conducted a criterion-referenced search using Web of Science, Science Direct, PubMed, and Google Scholar databases, selecting a total of 19 articles according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Statistical analyses were performed using comprehensive meta-analysis (CMA) software.</div></div><div><h3>Results</h3><div>The results showed an estimated overall prevalence of NCGS at 6.3% (95% CI: 2.8–6.6%). The prevalence was 6.3% (95% CI: 2.6–6.8%) in adults and 2.3% (95% CI: 0.4–4.3%) in children, and higher in women than in men, 3.9% (95% CI: 1.6–5.1%) versus 2.2% (95% CI: 0.06–2.2%), respectively. In terms of country income, the prevalence of NCGS was lower in high-income countries, estimated at 2.3% (95% CI: 1.6–6.5%), than in middle- and low-income countries, with a value of 4.1% (95% CI: 2.9–8.9%).</div></div><div><h3>Conclusion</h3><div>This systematic and meta-analysis reveals a high prevalence of NCGS, estimated, which varies according to age, sex, and country income. This finding underlines the importance of improving diagnostic and management strategies for this clinical condition.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Pages 131-141"},"PeriodicalIF":0.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of social media use on food habits, sleeping duration and weight status of Algerian university students","authors":"Fouzia Tebbani, Rihem Doukhani, Rania Mostefa-Ezzegai, Hayet Oulamara","doi":"10.1016/j.nupar.2025.02.002","DOIUrl":"10.1016/j.nupar.2025.02.002","url":null,"abstract":"<div><h3>Objectives</h3><div>To assess food habits, sleep duration and weight status of university students. Also, to investigate the impact of social media use on students’ food habits, sleeping and weight status.</div></div><div><h3>Materials and methods</h3><div>A cross-sectional descriptive study was conducted among 400 Algerian university students, from February 2024 to May 2024. Data related to social media usage, eating habits, physical activity and sleeping was collected. Weight and height were measured and Body mass index was calculated and classified according to the recommendations. Statistics were performed using StatviewTM and SPSS software.</div></div><div><h3>Results</h3><div>The majority of students (59.0%) used social media for two hours and more per day. Overweight students were significantly (<em>P</em> <!--><<!--> <!-->0.0001) the most likely to use social media platforms. Students who used social media for more than four hours were the most likely to have irregular meals (<em>P</em> <!-->=<!--> <!-->0.04), to skip breakfast, lunch, dinner (<em>P</em> <!--><<!--> <!-->0.05) and to snack between meals sugary and junk foods and drink sodas (<em>P</em> <!--><<!--> <!-->0.05). Students who used social media the most were those who sleep few hours (<em>P</em> <!-->=<!--> <!--><0.0001).</div></div><div><h3>Conclusion</h3><div>The study elucidated a complex relationship between food habits, social media usage and weight status among university students. It highlighted prevalent irregular eating patterns and frequent meal skipping, compounded by the significant impact of social media on dietary behaviors.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Pages 118-124"},"PeriodicalIF":0.5,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vânia Bentes de Miranda, Renata Ligia Guedes, Giedre Berretin-Félix
{"title":"Neurological level, acceptance of the modified diet, nutritional and water status after stroke","authors":"Vânia Bentes de Miranda, Renata Ligia Guedes, Giedre Berretin-Félix","doi":"10.1016/j.nupar.2025.02.003","DOIUrl":"10.1016/j.nupar.2025.02.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Individuals affected by cerebrovascular accident (CVA) may present oropharyngeal dysphagia, which may lead to dehydration and nutritional deficiencies.</div></div><div><h3>Objective</h3><div>Assess the influence of the neurological level after the CVA in the acceptance of the modified food consistency after speech-language pathology assessment, consequently, in the nutritional and water status, in individuals assisted by an interdisciplinary team.</div></div><div><h3>Methodology</h3><div>Longitudinal observational study developed in a general hospital with nutritional assessments in three different times, obtaining BMI and body analysis by BIA. Dietary acceptance was quantified daily during hospitalization and sodium test results were evaluated as an indicator of hydration level. Data were statistically analyzed using Spearman's correlation coefficient, ANOVA test, and also the Bonferroni and paired T student. A significance level of 5% was considered for inferential analyses and the confidence interval was 95%.</div></div><div><h3>Results</h3><div>Sample composed predominantly of elderly males. No correlations were found between the change in food consistency and nutritional and water status, oral intake and food acceptance of the individuals, but a statistically significant difference in the variables NIHSS and BIAMM% was observed. Over time, the average course level decreased and the average bioelectrical impedance at time 2 was higher than that at time 3. There wasn’t a significative correlation between water status and neurological level.</div></div><div><h3>Conclusion</h3><div>No influence of the neurological level after stroke was observed on the acceptance of the modified diet or nutritional and hydration status. However, when the variables were analyzed in isolation a decrease in NIHSS values and muscle loss (BIAMM%) was observed.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Pages 125-130"},"PeriodicalIF":0.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are metabolic risk parameters and MEDFICTS Score associated with tinnitus severity in adults?","authors":"Tuba Onay , Nursel Dal , Kevser Tari Selçuk , Sedat Arslan , Mümtaz Taner Torun","doi":"10.1016/j.nupar.2025.02.001","DOIUrl":"10.1016/j.nupar.2025.02.001","url":null,"abstract":"<div><h3>Background and aims</h3><div>Our hypothesis in this study was to investigate whether there is an association between metabolic risk parameters and the MEDFICTS score (meat, eggs, dairy products, fried foods, fats in bakery products, convenience foods, added fats at table and snacks) and tinnitus severity in adults.</div></div><div><h3>Methods</h3><div>This descriptive study was conducted with 331 adults aged 19–64. Data were collected through face-to-face interviews using data collection forms consisting of the Tinnitus Disability Questionnaire, MEDFICTS Dietary Assessment Questionnaire, metabolic risk parameters, and anthropometric measurements. Descriptive statistics, Student's <em>t</em>-test, and simple and multivariate linear regression analysis were applied to data analysis. The significance level of statistical tests was accepted as <em>P</em> <!--><<!--> <!-->0.05.</div></div><div><h3>Results</h3><div>The mean waist circumference (WC), fasting blood glucose, High Density Lipoprotein (HDL), Triglyceride (TG), Systolic Blood Pressure (SBP), and Diastolic Blood Pressure (DBP) were 89.30<!--> <!-->±<!--> <!-->13.42<!--> <!-->cm, 96.14<!--> <!-->±<!--> <!-->17.62<!--> <!-->mg/dL, 52.34<!--> <!-->±<!--> <!-->11.43<!--> <!-->mg/dL, 127.82<!--> <!-->±<!--> <!-->48.54<!--> <!-->mg/dL, 121.29<!--> <!-->±<!--> <!-->12.90<!--> <!-->mm/Hg and 73.49<!--> <!-->±<!--> <!-->9.34<!--> <!-->mm/Hg, respectively. The mean MEDFICTS score was 78.08<!--> <!-->±<!--> <!-->26.04 and 59.8% of the individuals needed dietary changes for heart health. The mean Tinnitus Disability Questionnaire total score was 40.17<!--> <!-->±<!--> <!-->22.14. 2.4% had moderate tinnitus and 1.5% had severe tinnitus. Fasting blood glucose (β: 0.524, <em>P</em> <!--><<!--> <!-->0.05) and MEDFICTS score (β: 0.459, <em>P</em> <!--><<!--> <!-->0.05) were positively associated with tinnitus severity, 24% of the change in tinnitus severity was explained by fasting blood glucose, and 17% by MEDFICTS score.</div></div><div><h3>Conclusion</h3><div>Increased fasting blood glucose and increased dietary intake of foods high in saturated fat and cholesterol are associated with increased tinnitus severity.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Pages 110-117"},"PeriodicalIF":0.5,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luna Desnot , Monelle Bertrand , Patrick Ritz , Charlotte Thomas
{"title":"Les répercussions bucco-dentaires des patients atteints de troubles du comportement alimentaire : mise au point et solutions préventives","authors":"Luna Desnot , Monelle Bertrand , Patrick Ritz , Charlotte Thomas","doi":"10.1016/j.nupar.2025.01.007","DOIUrl":"10.1016/j.nupar.2025.01.007","url":null,"abstract":"<div><div>Eating disorders such as anorexia nervosa, bulimia nervosa and binge eating disorder, are characterized by psychopathological disorders that affect patients’ relationship to food and their body perception. These disorders have repercussions on physical, mental and oral health. Oral manifestations include changes in the salivary glands, mucous membranes, periodontal tissues and teeth. Eating disorders can lead to poor oral health by altering salivary flow, increasing oral acidity and promoting the proliferation of pathogenic bacteria. Salivary pathologies, resulting from purging behaviors and the use of certain medications, can alter taste sensitivities and lead to hyposialia, a reduction in oral pH. Mucosal injuries are often caused by iatrogenic traumas, nutritional deficiencies, and chronic irritations that may require symptomatic treatment and vitamin supplementation. Nutritional deficiencies (vitamins C, D and B) have consequences on periodontal tissues, increasing the risk of periodontitis, tooth mobility and tooth loss. Dental lesions, such as erosions, cervical tooth wear and caries lesions, result from unbalanced eating behaviors and require rigorous oral hygiene, vitamin supplementation and an early intervention to avoid severe complications. The care of patients with eating disorders requires a multidisciplinary approach, especially with the oral health, involving regular visits to the dentist and preventive measures to improve patients’ quality of life.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 2","pages":"Pages 88-94"},"PeriodicalIF":0.5,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144123438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"L’éditorial de la présidente de la SNFCM","authors":"Francisca Joly","doi":"10.1016/j.nupar.2025.01.006","DOIUrl":"10.1016/j.nupar.2025.01.006","url":null,"abstract":"","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"39 1","pages":"Page 1"},"PeriodicalIF":0.5,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}