Nutrition Clinique et Metabolisme最新文献

{"title":"Mapping food and nutrition literacy in non-communicable disease contexts: A scoping review","authors":"Omer Qutaiba B. Allela ,&nbsp;Abdulkareem Shareef ,&nbsp;Hayder Naji Sameer ,&nbsp;Ahmed Yaseen ,&nbsp;Zainab H. Athab ,&nbsp;Mohaned Adil","doi":"10.1016/j.nupar.2026.103031","DOIUrl":"10.1016/j.nupar.2026.103031","url":null,"abstract":"<div><h3>Objectives</h3><div>Food and nutrition literacy (FNL), the ability to access, understand, evaluate, and apply nutrition information, is increasingly recognized as a critical determinant of dietary behavior and chronic disease outcomes. This scoping review aimed to synthesize global evidence on the prevalence, measurement approaches, and clinical and behavioral correlates of FNL among adults living with non-communicable diseases (NCDs), and to clarify its relevance for clinical care and public health practice.</div></div><div><h3>Material and methods</h3><div>Following the PRISMA-ScR guidelines, PubMed, Scopus, Web of Science, and Google Scholar were systematically searched for peer-reviewed studies up to October 30, 2025. Eligible studies assessed functional, interactive, or critical FNL in adults with NCDs. Data were extracted on study characteristics, FNL measurement, and associations with behavioral or clinical outcomes. Two researchers independently performed searches of electronic databases, study selection, and data extraction, with discrepancies resolved by consensus or a third reviewer.</div></div><div><h3>Results</h3><div>Thirteen studies, covering 5004 participants across diverse settings, were included. FNL levels were generally suboptimal, with pronounced deficits in label interpretation, portion control, meal planning, and critical appraisal. Higher FNL was consistently associated with healthier dietary behaviors, improved self-management, and better cardiometabolic indicators. Functional literacy supported adherence to evidence-based diets, while interactive and critical literacy enhanced patient-provider communication and resilience against misleading nutrition information.</div></div><div><h3>Conclusion</h3><div>FNL is a modifiable, clinically actionable determinant of chronic disease management. Integrating FNL assessment and education into care pathways can empower patients, strengthen long-term adherence, and support population-level NCD prevention.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 2","pages":"Article 103031"},"PeriodicalIF":0.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating inflammation and nutrition: A multi-visual meta-analysis of serum biomarkers and COVID-19 severity","authors":"Nayebali Ahmadi ,&nbsp;Maryam Shahali ,&nbsp;Mohammad Javad Hossein Tehrani ,&nbsp;Danial Sarlak ,&nbsp;Rajab Mardani","doi":"10.1016/j.nupar.2026.103034","DOIUrl":"10.1016/j.nupar.2026.103034","url":null,"abstract":"<div><h3>Background</h3><div>The COVID-19 pandemic has revealed substantial heterogeneity in biomarker profiles associated with disease severity. While inflammation-driven responses are implicated in progression to critical illness, the role of nutritional status and micronutrient levels in shaping outcomes remains incompletely understood. This study integrates 35 studies using a multi-visual meta-analytic approach to delineate the relationships between inflammatory biomarkers, nutritional/vitamin markers, and severe COVID-19 outcomes.</div></div><div><h3>Methods</h3><div>We conducted a systematic search of major databases (PubMed/MEDLINE, Embase, and Web of Science) for studies reporting quantitative associations between serum biomarkers and COVID-19 severity or mortality. Data were harmonized to standardized mean differences (SMDs) where possible. A multi-plot synthesis (forest, funnel, volcano, and bubble plots) was employed to capture effect sizes, precision, heterogeneity, publication bias, and variance. Inclusion criteria encompassed adult participants with confirmed SARS-CoV-2 infection who reported inflammatory markers (CRP, IL-6, ferritin), nutritional markers (e.g., albumin, pre-albumin), vitamins (e.g., A, C, D, E), and immune markers, where available. Exclusion criteria included pediatric populations and studies lacking extractable quantitative data.</div></div><div><h3>Results</h3><div>Across 35 studies, inflammatory biomarkers were consistently elevated in severe COVID-19, with CRP, IL-6, and ferritin showing directionally positive associations with adverse outcomes. Nutritional and micronutrient markers tended to be reduced in severe cases, with albumin and several vitamins (notably vitamin D, C, and E) frequently depleted, though substantial between-study heterogeneity existed. The integrated visualizations revealed concordant signals of inflammation amid variable nutritional statuses, while funnel plots suggested modest small-study effects that did not materially alter the overall conclusions. Sensitivity analyses confirmed robustness of the main inflammation-associated findings and highlighted context-dependent variability for nutritional markers. Collectively, the results underscore a central inflammatory axis in severe COVID-19, modulated by nutritional and micronutrient status, with implications for risk stratification and supportive care strategies.</div></div><div><h3>Conclusions</h3><div>Our multi-plot synthesis provides a cohesive narrative linking systemic inflammation with adverse outcomes in COVID-19 and delineates nuanced roles for nutritional and vitamin-related factors. These findings support concurrent emphasis on anti-inflammatory management and nutritional optimization in high-risk patients, while also guiding future research to disentangle context-specific moderators and to test targeted nutritional interventions.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 2","pages":"Article 103034"},"PeriodicalIF":0.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146190206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting the brain-gut-taste axis: The role of GLP-1-mediated SGLT-1 signaling in metabolic diseases","authors":"Yang Heng ,&nbsp;Yang Qiuming","doi":"10.1016/j.nupar.2026.103032","DOIUrl":"10.1016/j.nupar.2026.103032","url":null,"abstract":"<div><div>The global pandemic of metabolic diseases, such as obesity and type 2 diabetes, underscores an urgent need for innovative therapeutic strategies. Emerging evidence has established the intestine as a central player in nutrient sensing and systemic metabolic regulation. This review systematically delineates the critical role of the sodium-glucose cotransporter 1 (SGLT-1) in metabolic control and elaborates on the molecular mechanisms through which glucagon-like peptide-1 (GLP-1) modulates metabolic homeostasis via the brain-gut-taste axis. By reviewing and integrating recent evidence, we propose a novel paradigm wherein GLP-1, through the modulation of intestinal SGLT-1 signaling, influences taste perception and food preferences, thereby orchestrating systemic metabolic outcomes. This mechanism provides a compelling rationale for developing therapies that would target the gut-brain axis, representing a potential breakthrough in managing metabolic disorders. Finally, we outline current limitations and future challenges in translating these insights into clinical practice, to propose a framework for guiding research in this promising field.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 2","pages":"Article 103032"},"PeriodicalIF":0.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146190207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between dietary fiber consumption and chronic obstructive pulmonary disease: A systematic review and meta-analysis","authors":"Qiang Lu ,&nbsp;Lei Zhang ,&nbsp;Yan Wang ,&nbsp;Huaiyu Hao","doi":"10.1016/j.nupar.2025.103029","DOIUrl":"10.1016/j.nupar.2025.103029","url":null,"abstract":"<div><h3>Objective</h3><div>This study with a systematic review and meta-analysis design aimed to specially investigate the relationship between dietary fiber intake and chronic obstructive pulmonary disease.</div></div><div><h3>Materials and methods</h3><div>A search was performed in the databases of Web of Science, PubMed, and Scopus. The articles retrieved from these databases were carefully reviewed and screened by the research team. Ultimately, articles that met the established inclusion and exclusion criteria were selected for data extraction. The quality of these studies was evaluated using the Joanna Briggs Institute (JBI) critical appraisal instruments. To integrate the findings, a meta-analysis was performed to aggregate the reported odds ratios and hazard ratios from the chosen studies.</div></div><div><h3>Results</h3><div>Fifteen studies were entered into the review. Thirteen of 15 reviewed papers (86.7 percent) revealed that there is an association between dietary fiber intake and risk of COPD. The values of the odds ratio and hazard ratio related to the impact of fiber consumption on the decreased risk of COPD were between 0.46 to 0.98 and 0.54 to 0.70. The results of meta-analysis showed that fiber intake can decrease the risk of COPD [odd ratio: 0.866 (95% CI: 0.773–0.971); <em>P</em> <!-->=<!--> <!-->0.014; I² <!-->=<!--> <!-->79.30 and hazard ratio: 0.636 (95% CI: 0.538–0.751); <em>P</em> <!-->&lt;<!--> <!-->0.001; I² <!-->=<!--> <!-->41.29].</div></div><div><h3>Conclusion</h3><div>The results showed that fiber intake can significantly reduce the risk of COPD. Hence, it is suggested that dietary plans on fiber intake are implemented, especially in poor countries.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 2","pages":"Article 103029"},"PeriodicalIF":0.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146039467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atteintes hépatiques en lien avec la dénutrition dans l’anorexie mentale – Revue de la littérature","authors":"Jade Deglaire,&nbsp;Thomas Mouillot","doi":"10.1016/j.nupar.2025.103028","DOIUrl":"10.1016/j.nupar.2025.103028","url":null,"abstract":"<div><div>Malnutrition – particularly in anorexia nervosa – can have significant hepatic repercussions. As the central organ of metabolism, the liver is particularly vulnerable to nutritional disturbances. Two principal forms of hepatitis related to malnutrition have been described in the literature: starvation hepatitis and refeeding-induced hepatitis. The former mainly results from excessive hepatocellular autophagy and hypoxia due to dehydration and hypovolemia, and is usually associated with clinical symptoms. In contrast, the latter is frequently linked to inappropriate refeeding syndrome, is clinically asymptomatic, and occurs during overly rapid or calorie-dense refeeding, leading to hepatic steatosis. This article is based on an international literature review highlighting diagnostic criteria, pathophysiological mechanisms (autophagy, hypoxia, steatosis), specific risks, and therapeutic management of liver diseases associated with malnutrition in the context of anorexia nervosa.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 2","pages":"Article 103028"},"PeriodicalIF":0.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146006588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact de l’augmentation du temps diététique sur le dépistage et la valorisation médicoéconomique de la dénutrition en chirurgie orthopédique","authors":"Vérane Peyratout Gueho ,&nbsp;Simon Atmeare ,&nbsp;Clarysse Addario ,&nbsp;Marine Tourscher ,&nbsp;Emilie Racano","doi":"10.1016/j.nupar.2026.103030","DOIUrl":"10.1016/j.nupar.2026.103030","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the impact of increasing dietitian presence in an orthopedic surgery department on malnutrition screening and the associated healthcare revenue.</div></div><div><h3>Methods</h3><div>A retrospective observational study was conducted in the orthopedic surgery department of a hospital over two consecutive periods (January and February 2023). The allocated dietitian time was increased from 10 to 50%. Data collected included the number of patients hospitalized for more than 48<!--> <!-->hours, dietitian consultations, malnutrition diagnoses, upgraded Diagnosis-Related Group (DRG) classifications, and the corresponding financial valuation.</div></div><div><h3>Results</h3><div>The increase in dietitian time led to a significant rise in dietetic consultations (15.2 vs. 83.8%; <em>P</em> <!-->&lt;<!--> <!-->0.001), malnutrition diagnoses (7 vs. 26; <em>P</em> <!-->=<!--> <!-->0.0039), and upgraded hospital stays (5 vs. 15). Monthly financial valuation quadrupled from €9,517 to €41,801. The malnutrition coding rate in the department increased from 6.7 to 18.3%, while it remained stable at the institutional level.</div></div><div><h3>Conclusion</h3><div>Enhancing dietitian presence significantly improved malnutrition screening and coding, with substantial financial impact. This reorganization highlights the value of increasing human resources dedicated to hospital nutrition. It contributes to improved quality of care and resource optimization, aligning with the objectives of the French National Nutrition and Health Program (PNNS).</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 2","pages":"Article 103030"},"PeriodicalIF":0.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146080694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L’éditorial du président de la SNFCM","authors":"Didier Quilliot","doi":"10.1016/j.nupar.2026.103035","DOIUrl":"10.1016/j.nupar.2026.103035","url":null,"abstract":"","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 1","pages":"Article 103035"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147396493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of assessing postherpetic neuralgia based on the systemic immune-inflammation index and prognostic nutritional index","authors":"HuaAn Sun,&nbsp;XiaoHui Li","doi":"10.1016/j.nupar.2025.06.004","DOIUrl":"10.1016/j.nupar.2025.06.004","url":null,"abstract":"<div><h3>Objective</h3><div>This study was to investigate the clinical value of the systemic immune-inflammation index (SII) and prognostic nutritional index (PNI) in assessing the risk of developing postherpetic neuralgia (PHN) and to analyze the effects of inflammation and nutritional status on PHN.</div></div><div><h3>Methods</h3><div>Patients with herpes zoster were enrolled and divided into the PHN group and the non-PHN group. The clinical data and blood parameters of these patients were collected. The performance of SII and PNI alone and in combination in distinguishing between patients with and without PHN was investigated by ROC. Patients were stratified into three groups of high, medium, and low risk based on the cut-off values of SII and PNI. Kaplan–Meier curves and Cox risk regression were performed to analyze the association between PHN risk stratification and relevant factors.</div></div><div><h3>Results</h3><div>The mean age of patients in the PHN group was significantly higher than that in the non-PHN group, and the proportion of hemorrhagic rash was higher. Neutrophil count and SII were significantly higher, whereas plasma albumin levels were significantly lower in the PHN group. The best predictive efficacy was achieved by SII and PNI in combination, and the incidence of PHN in the high-risk group was significantly higher than that in the low-risk group. Age, neutrophil count, and SII were independent risk factors for PHN, while plasma albumin and PNI were protective factors.</div></div><div><h3>Conclusion</h3><div>SII-PNI serves as an effective predictor of PHN risk, driven by hyperinflammation and nutritional status imbalance.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 1","pages":"Article 103002"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abstinence from alcohol combined with inhibition of IL-17 may be an Effective treatment for alcoholic liver disease","authors":"Shuang Zhao ,&nbsp;Jian-He Gan","doi":"10.1016/j.nupar.2025.09.003","DOIUrl":"10.1016/j.nupar.2025.09.003","url":null,"abstract":"<div><h3>Background</h3><div>Alcohol liver disease (ALD) is one of the leading causes of liver disease-related deaths worldwide, but there is still no ideal treatment for ALD.</div></div><div><h3>Objective</h3><div>To study the relationship between IL-17 and the progression of ALD disease.</div></div><div><h3>Methods</h3><div>Alcohol drinkers (<em>n</em> <!-->=<!--> <!-->123; 42, 39, and 42 participants with alcohol consumption of<!--> <!-->&lt;<!--> <!-->70, 70–140, and 140–280<!--> <!-->g/week, respectively), patients with ALD (<em>n</em> <!-->=<!--> <!-->51; 26, 16, and 9 patients with fatty liver, chronic hepatitis, and cirrhosis, respectively), patients with alcohol-related hepatocellular carcinoma (HCC) (<em>n</em> <!-->=<!--> <!-->7) and healthy controls (<em>n</em> <!-->=<!--> <!-->20) were selected. IL-17 in peripheral blood was investigated. After 1 month, 6 months, and 1 year of abstinence from alcohol, IL-17 in peripheral blood was detected again.</div></div><div><h3>Results</h3><div>IL-17 in peripheral blood increased in patients with ALD and HCC than that in the control group. After 6 months of abstinence from alcohol, IL-17 in peripheral blood decreased in alcohol drinkers and ALD groups. There was no significant change in IL-17 level in peripheral blood of the HCC group after abstinence from alcohol.</div></div><div><h3>Conclusion</h3><div>Abstaining from alcohol can reduce IL-17 levels in the peripheral blood of patients with alcoholic liver disease (ALD) to some extent, suggesting that IL-17 may play a significant role in the pathogenesis of ALD.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 1","pages":"Article 103015"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of preoperative nutritional status on postoperative complications and length of hospital stay in patients undergoing abdominal surgery","authors":"Çağla Toprak ,&nbsp;Ayşe Betül Bilen ,&nbsp;Elif Hamarat ,&nbsp;Alpen Yahya Gümüşoğlu","doi":"10.1016/j.nupar.2025.11.001","DOIUrl":"10.1016/j.nupar.2025.11.001","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to evaluate the role and predictive value of preoperative nutritional status on postoperative outcomes by using the Nutritional Risk Screening 2002 (NRS-2002) tool and biochemical parameters.</div></div><div><h3>Methods</h3><div>A total of 565 patients aged between 19 and 65 years who underwent elective abdominal surgery under general anesthesia between January 1st, 2023, and January 1st, 2024, were included in the study. Preoperative nutritional status was assessed using the NRS-2002 tool. Biochemical parameters were analyzed to identify factors associated with postoperative complications.</div></div><div><h3>Results</h3><div>Data from 565 patients with a mean age of 57.98<!--> <!-->±<!--> <!-->15.73 years were analyzed. According to NRS-2002 scores, 12% of the patients were identified as malnourished. Postoperative infection was the most common complication, occurring in 22.3% of patients. Among the evaluated parameters, the ASA score showed the highest discriminative power (AUC<!--> <!-->=<!--> <!-->0.752, 95% CI: 0.689–0.812). Similarly, postoperative C-reactive protein (CRP2) demonstrated a significant discriminative performance (AUC<!--> <!-->=<!--> <!-->0.655, 95% CI: 0.583–0.728). The risk of malnutrition was 3.56 times higher in individuals with CRP2 levels above 96.5<!--> <!-->mg/L.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that patients with low NRS-2002 scores and malnutrition had prolonged postoperative hospital stays.</div></div>","PeriodicalId":54702,"journal":{"name":"Nutrition Clinique et Metabolisme","volume":"40 1","pages":"Article 103017"},"PeriodicalIF":0.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147538002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}