非乳糜泻麸质敏感性在普通人群中的患病率：系统回顾和荟萃分析

IF 0.5 4区医学 Q4 ENDOCRINOLOGY & METABOLISM

Nutrition Clinique et Metabolisme Pub Date : 2025-04-15 DOI:10.1016/j.nupar.2025.03.001

Wissal Zkhiri , Morad Guennouni , Aïcha Bourrahouat , Nysrine Mannani , Imane Ait Sab , Adil Ait Rami , Khadija Krati , Brahim Admou

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引用次数: 0

摘要

目的本系统综述和荟萃分析旨在确定非乳糜泻谷蛋白敏感性（NCGS）在普通人群中的总体患病率。方法使用Web of Science、Science Direct、PubMed和b谷歌Scholar数据库进行标准参考检索，根据系统评价和meta分析（PRISMA）指南选择了19篇文章。采用综合meta分析（CMA）软件进行统计分析。结果NCGS的总体患病率估计为6.3% （95% CI: 2.8-6.6%）。成人患病率为6.3% (95% CI: 2.6-6.8%)，儿童患病率为2.3% (95% CI: 0.4-4.3%)，女性高于男性，分别为3.9% （95% CI: 1.6-5.1%）和2.2% （95% CI: 0.06-2.2%）。就国家收入而言，NCGS的患病率在高收入国家较低，估计为2.3% (95% CI: 1.6-6.5%)，而在中低收入国家为4.1% （95% CI: 2.9-8.9%）。结论：该系统和荟萃分析显示，NCGS的患病率很高，根据年龄、性别和国家收入而有所不同。这一发现强调了改善诊断和管理策略对这种临床状况的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The prevalence of non-celiac gluten sensitivity in the general population: Systematic review and meta-analysis

Objective

This systematic review and meta-analysis aimed to determine the overall prevalence of non-celiac gluten sensitivity (NCGS) in the general population.

Methods

We conducted a criterion-referenced search using Web of Science, Science Direct, PubMed, and Google Scholar databases, selecting a total of 19 articles according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Statistical analyses were performed using comprehensive meta-analysis (CMA) software.

Results

The results showed an estimated overall prevalence of NCGS at 6.3% (95% CI: 2.8–6.6%). The prevalence was 6.3% (95% CI: 2.6–6.8%) in adults and 2.3% (95% CI: 0.4–4.3%) in children, and higher in women than in men, 3.9% (95% CI: 1.6–5.1%) versus 2.2% (95% CI: 0.06–2.2%), respectively. In terms of country income, the prevalence of NCGS was lower in high-income countries, estimated at 2.3% (95% CI: 1.6–6.5%), than in middle- and low-income countries, with a value of 4.1% (95% CI: 2.9–8.9%).

Conclusion

This systematic and meta-analysis reveals a high prevalence of NCGS, estimated, which varies according to age, sex, and country income. This finding underlines the importance of improving diagnostic and management strategies for this clinical condition.

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来源期刊

Nutrition Clinique et Metabolisme 医学-内分泌学与代谢

CiteScore

0.80

自引率

16.70%

发文量

216

审稿时长

78 days

期刊介绍： Nutrition Clinique et Métabolisme is the journal of the French-speaking Society of Enteral and Parenteral Nutrition. Associating clinicians, biologists, pharmacists, and fundamentalists, the articles presented in the journal concern man and animals, and deal with organs and cells. The goal is a better understanding of the effects of artificial nutrition and human metabolism. Original articles, general reviews, update articles, technical notes and communications are published, as well as editorials and case reports.