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Growth Disturbances in Children With Rheumatologic Diseases. 风湿病患儿的生长障碍
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260127-07
Sangeeta Sule
{"title":"Growth Disturbances in Children With Rheumatologic Diseases.","authors":"Sangeeta Sule","doi":"10.3928/19382359-20260127-07","DOIUrl":"10.3928/19382359-20260127-07","url":null,"abstract":"<p><p>Growth impairment is a well-recognized complication in pediatric rheumatologic diseases, particularly juvenile idiopathic arthritis, systemic lupus erythematosus, and systemic sclerosis. These conditions interfere with normal childhood development through the combined influences of chronic inflammation, altered endocrine signaling, malnutrition, delayed puberty, reduced physical activity, and medication toxicity-especially glucocorticoids. Although the advent of biologic therapy has dramatically improved disease control and enhanced growth potential, many children continue to exhibit significant growth delays that persist into adulthood. This review synthesizes current knowledge on mechanisms of growth suppression in pediatric rheumatologic diseases, describes disease-specific effects, and discusses contemporary therapeutic strategies aimed at optimizing linear growth and overall development.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e143-e146"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burn and Scald Injuries: Prevention and Anticipatory Guidance. 烧伤和烫伤：预防和预期指导。
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260311-02
David Hong
{"title":"Burn and Scald Injuries: Prevention and Anticipatory Guidance.","authors":"David Hong","doi":"10.3928/19382359-20260311-02","DOIUrl":"10.3928/19382359-20260311-02","url":null,"abstract":"<p><p>Burn injuries remain a significant source of morbidity among children in the United States and represent a common cause of pediatric injury encountered in both emergency and outpatient settings. Children frequently present with burns of varying severity, ranging from minor injuries managed in primary care clinics to more serious burns requiring emergency evaluation and specialized treatment. As pediatricians, it is key to understand burn types and how varying mechanisms of injury disproportionately impact certain age groups more than others to provide effective and tailored anticipatory guidance to parents and caregivers.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e123-e126"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidisciplinary Perspectives on Growth in Pediatrics. 儿科生长的多学科视角。
IF 1 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260127-05
Natasha Shur, Carrie Daymont
{"title":"Multidisciplinary Perspectives on Growth in Pediatrics.","authors":"Natasha Shur, Carrie Daymont","doi":"10.3928/19382359-20260127-05","DOIUrl":"https://doi.org/10.3928/19382359-20260127-05","url":null,"abstract":"","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e127-e129"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Stepwise Approach to Macrocephaly: Clinical Clues to the Rare Diagnosis of PTEN Hamartoma Tumor Syndrome. 大头畸形的逐步诊断：PTEN错构瘤综合征罕见诊断的临床线索。
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260309-02
Nidhi A Gupta, Natasha Shur, Seth I Berger
{"title":"A Stepwise Approach to Macrocephaly: Clinical Clues to the Rare Diagnosis of PTEN Hamartoma Tumor Syndrome.","authors":"Nidhi A Gupta, Natasha Shur, Seth I Berger","doi":"10.3928/19382359-20260309-02","DOIUrl":"10.3928/19382359-20260309-02","url":null,"abstract":"<p><p>Macrocephaly, defined as a large head size, has a very broad differential and sometimes can be challenging to differentiate as benign versus indicative of pathology. In this review, we outline a stepwise approach to improving diagnosis of neurogenetic disorders versus other causes using the example of PTEN (phosphatase and TENsin homolog) Hamartoma Tumor Syndrome (PHTS). PHTS is a multiple hamartoma syndrome with medical management implications including the need for tumor surveillance, but often cases are not diagnosed until later in adulthood. Our review emphasizes the utility of using head circumference <i>z</i> scores in combination with other features as a triage tool for genetic identification of disorders such as PHTS.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e139-e142"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trust, Authority, and the Future of Clinical Care. 信任、权威和临床护理的未来。
IF 1 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260311-03
Ali Rahman, Lolita Alcocer Alkureishi, Joseph R Hageman
{"title":"Trust, Authority, and the Future of Clinical Care.","authors":"Ali Rahman, Lolita Alcocer Alkureishi, Joseph R Hageman","doi":"10.3928/19382359-20260311-03","DOIUrl":"https://doi.org/10.3928/19382359-20260311-03","url":null,"abstract":"","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e120-e122"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex Differences in Statural Growth Impairment in Pediatric Crohn's Disease. 儿童克罗恩病发育障碍的性别差异
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260127-02
Neera Gupta
{"title":"Sex Differences in Statural Growth Impairment in Pediatric Crohn's Disease.","authors":"Neera Gupta","doi":"10.3928/19382359-20260127-02","DOIUrl":"10.3928/19382359-20260127-02","url":null,"abstract":"<p><p>Statural growth is a dynamic marker of disease activity in patients with Crohn's disease. Statural growth impairment is a common complication of Crohn's disease, occurring more frequently in male patients. Delayed bone age is common in Crohn's disease, occurring more frequently in female patients. Data suggest sex-specific pathways lead to growth impairment in Crohn's disease and highlight the essential need for the development of sex-specific, risk-based treatment approaches. Initial referral to endocrinology rather than gastroenterology for children diagnosed with Crohn's disease presenting with growth impairment may lead to delays in diagnosis and increased disease severity at the time of diagnosis. Growth impairment is associated with meaningful impacts on quality of life, psychosocial functioning, and family well-being. As substantial research is needed to clarify ongoing uncertainty regarding the optimal initial subspecialty referral for children presenting with growth impairment and the potential for diagnostic delay with sequential evaluation, a strategy of parallel referral to gastroenterology and endocrinology may be warranted.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e135-e138"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growth in Children Affected by HIV. 受艾滋病毒影响的儿童的生长。
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-04-01 DOI: 10.3928/19382359-20260127-03
Kira J Nightingale, Elizabeth D Lowenthal
{"title":"Growth in Children Affected by HIV.","authors":"Kira J Nightingale, Elizabeth D Lowenthal","doi":"10.3928/19382359-20260127-03","DOIUrl":"10.3928/19382359-20260127-03","url":null,"abstract":"<p><p>Children exposed to HIV in utero are at risk of adverse growth outcomes, even if they do not acquire HIV perinatally. Some growth impacts begin before birth, with children exposed to HIV being more likely to be born preterm and small for gestational age, as well as with low birthweight. Children born with HIV (CHIV) exhibit more growth differences than children exposed to HIV in utero but born uninfected (CHEU); although, early treatment with antiretroviral therapy significantly improves their growth outcomes. CHEU are also vulnerable to poor growth postnatally. The causes are multifaceted and include increased susceptibility to infection and socioeconomic vulnerabilities. Pediatricians must be aware of the unique growth vulnerabilities of CHIV and CHEU, so they can carefully follow growth while assessing potential drivers of growth disparities for each child to help ensure that they achieve their full growth potential.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 4","pages":"e147-e151"},"PeriodicalIF":0.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147610560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Autonomic Dysfunction and Postural Orthostatic Tachycardia Syndrome: What Every Frontline Clinician Needs to Know. 自主神经功能障碍和体位性心动过速综合征：每个一线临床医生都需要知道的。
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-03-01 DOI: 10.3928/19382359-20260112-05
Kirti Sivakoti, Meeryo C Choe
{"title":"Autonomic Dysfunction and Postural Orthostatic Tachycardia Syndrome: What Every Frontline Clinician Needs to Know.","authors":"Kirti Sivakoti, Meeryo C Choe","doi":"10.3928/19382359-20260112-05","DOIUrl":"10.3928/19382359-20260112-05","url":null,"abstract":"<p><p>Autonomic dysfunction, particularly postural orthostatic tachycardia syndrome (POTS), is increasingly recognized in adolescents and young adults. Early recognition in primary care is critical, as these conditions can substantially affect functioning, school participation, quality of life, and health care utilization. This review provides practical, clinically relevant guidance for pediatric and family medicine clinicians, and emphasizes recognition, office-based assessment, initial management, and referral strategies. Key considerations include differentiating POTS from mimicking conditions, evaluating functional impact, and implementing structured lifestyle interventions. Medications are reserved for patients with significant functional impairment despite conservative management, with a focus on setting realistic expectations. Case vignettes illustrate common phenotypes and highlight practical approaches to individualized care. By providing clear frameworks for evaluation and management, primary care clinicians can reduce unnecessary specialty visits, improve patient outcomes, and facilitate coordinated care across multidisciplinary teams.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 3","pages":"e90-e96"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postural Orthostatic Tachycardia Syndrome and Chronic Orthostatic Intolerance: Common, Challenging, and Manageable. 体位性站立性心动过速综合征和慢性站立性不耐受：常见、具有挑战性和可控制的。
IF 1 4区 医学
Pediatric Annals Pub Date : 2026-03-01 DOI: 10.3928/19382359-20260112-02
Kelsey M Klaas, Philip R Fischer
{"title":"Postural Orthostatic Tachycardia Syndrome and Chronic Orthostatic Intolerance: Common, Challenging, and Manageable.","authors":"Kelsey M Klaas, Philip R Fischer","doi":"10.3928/19382359-20260112-02","DOIUrl":"https://doi.org/10.3928/19382359-20260112-02","url":null,"abstract":"","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 3","pages":"e88-e89"},"PeriodicalIF":1.0,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prioritizing Function: Practical Management of Orthostatic Intolerance and Autonomic Dysfunction. 优先考虑功能：直立不耐受和自主神经功能障碍的实际管理。
IF 0.9 4区 医学
Pediatric Annals Pub Date : 2026-03-01 DOI: 10.3928/19382359-20260112-01
Lindsey D Daon, Shelley P Ahrens, Lytitia M Shea, Cynthia Harbeck-Weber, Jeannie Clark, Christine A Matarese, Amy E Rabatin, Alexandar E Gurfinkel
{"title":"Prioritizing Function: Practical Management of Orthostatic Intolerance and Autonomic Dysfunction.","authors":"Lindsey D Daon, Shelley P Ahrens, Lytitia M Shea, Cynthia Harbeck-Weber, Jeannie Clark, Christine A Matarese, Amy E Rabatin, Alexandar E Gurfinkel","doi":"10.3928/19382359-20260112-01","DOIUrl":"10.3928/19382359-20260112-01","url":null,"abstract":"<p><p>Chronic orthostatic intolerance (COI), a common symptom of autonomic dysfunction (AD), in adolescents is a heterogeneous condition characterized by symptoms that worsen upon standing and improve with recumbency. Nonpharmacologic management is the foundation of treatment and focuses on restoring autonomic balance, improving conditioning, and supporting functional recovery. This review summarizes current evidence-based strategies, including volume expansion through increased fluid and salt intake, use of compression garments, and gradual reconditioning exercises. Additional approaches, such as optimizing sleep, nutrition, and psychological well-being, address the multifactorial contributors to COI/AD. Education and reassurance play key roles in reducing symptom-related anxiety and promoting adherence. A multidisciplinary approach involving clinicians, families, and schools can enhance long-term outcomes. Emphasizing functional improvement fosters resilience and recovery, aligning treatment goals with adolescent development and quality of life. Clinicians should prioritize early education and behavioral interventions to promote sustainable recovery without reliance on medication.</p>","PeriodicalId":54633,"journal":{"name":"Pediatric Annals","volume":"55 3","pages":"e102-e107"},"PeriodicalIF":0.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147357525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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