Wan-Lin Cheng, Chih-Cheng Chang, Kun-Chia Chang, Hsiao-Wei Huang, Jian-An Su, Mark D Griffiths, Marc N Potenza, Chung-Ying Lin
{"title":"Quality of life among people with substance use disorders: A serial mediation model considering self-stigma and psychological distress.","authors":"Wan-Lin Cheng, Chih-Cheng Chang, Kun-Chia Chang, Hsiao-Wei Huang, Jian-An Su, Mark D Griffiths, Marc N Potenza, Chung-Ying Lin","doi":"10.1080/13548506.2026.2709042","DOIUrl":"https://doi.org/10.1080/13548506.2026.2709042","url":null,"abstract":"<p><p>People with substance use disorders (PWSUDs) frequently experience multifaceted challenges, including depression, stigma, and social instability, which can negatively affect their quality of life (QoL). The present study explored the potential predictors of QoL among PWSUDs. The sample consisted of 300 PWSUDs (85% males; mean [SD] age = 44.73 [10.01] years), comprising equal groups of PWSUDs with amphetamine, opioid, and alcohol concerns. Variables such as education, employment, depression, self-esteem, and stigma were assessed. The Taiwan version of the World Health Organization Quality of Life (WHOQOL) Questionnaire was adapted to assess QoL. Hierarchical regression analyses were conducted to examine associations with QoL across four domains. A multiple mediator modeling approach was used to assess whether self-stigma and depression mediated the relationship between perceived stigma and QoL. Higher depression scores were consistently associated with lower QoL across all domains. Education and employment were positively associated with physical QoL. In the psychological domain, both lower depression and higher self-stigma were associated with higher QoL. Perceived stigma was negatively associated with social QoL, and lower education predicted poorer environmental QoL. Mediation analyses suggested that depression played a stronger mediating role than self-stigma in the association between perceived stigma and QoL. Depression and stigma significantly related to QoL among PWSUDs. Mediational pathways suggest that targeting depression may mediate the negative association between stigma and QoL. Interventions addressing both affective and social dimensions may help promote recovery.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1-17"},"PeriodicalIF":2.2,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148665239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors associated with meaning in life of patients with multiple myeloma in Korea.","authors":"Yoorin Cho, Yangsook Yoo","doi":"10.1080/13548506.2025.2565512","DOIUrl":"10.1080/13548506.2025.2565512","url":null,"abstract":"<p><p>In this descriptive survey study, we aimed to identify factors influencing the meaning in life of patients with multiple myeloma. We recruited and analyzed 204 patients with multiple myeloma who visited the outpatient clinic or received treatment in wards at Seoul St Mary's Hospital, the Catholic University of Korea. Data were collected from these participants using a structured questionnaire and analyzed using SPSS 21.0 through t-tests, analysis of variance, Scheffé's test, Pearson's correlation coefficient, and multiple regression analyses. The factors associated the meaning in life of patients with multiple myeloma were gratitude disposition, social support, positive emotional experiences, and subjective well-being (SWB). Meaning in life had a mean score of 5.29 of 7; gratitude disposition and social support had mean scores of 5.94 of 7 and 3.81 of 5, respectively; while SWB had mean scores of 5.22 and 3.03 of 7 for positive and negative emotional experiences, respectively. The findings of this study indicate the importance of considering patients' gratitude disposition, social support, and positive emotional experiences when developing interventions to support the pursuit of meaning in life among patients with multiple myeloma.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1842-1857"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chris Segrin, Terry A Badger, Kristin E Morrill, Alla Sikorskii
{"title":"Neighborhood disadvantage and social isolation are associated with psychological and physical symptom burden in cancer survivors.","authors":"Chris Segrin, Terry A Badger, Kristin E Morrill, Alla Sikorskii","doi":"10.1080/13548506.2025.2564313","DOIUrl":"10.1080/13548506.2025.2564313","url":null,"abstract":"<p><p>The specific aim of this project was to test a model of neighborhood disadvantage and social isolation as potential correlates of physical and psychological symptoms in a sample of cancer survivors who are either in, or have recently completed, treatment. Participants were 846 cancer survivors who were currently in treatment (<i>N</i> = 400) or who had recently completed treatment (<i>N</i> = 446). The sample was 80% women with a mean age of 58.72 (SD = 12.81) years. The most common type of cancer represented in the sample was breast (51%). Participants completed measures of physical and psychological symptoms and social isolation and social support. These data were merged with the 2021 American Community Survey indicators of neighborhood disadvantage by zip code and county. After controlling for Hispanic ethnicity, education, and household income, survivors who resided in disadvantaged neighborhoods, as indicated by the fraction of residents living in poverty, receiving income assistance, without health insurance, and with less than a high school education, reported higher psychological and physical symptoms. Similarly, social isolation was positively associated with psychological symptoms and physical symptoms. Residing in a disadvantaged neighborhood and feeling socially isolated may represent independent risk factors for psychological morbidity and physical symptom burden among cancer survivors.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1678-1692"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Examining the effects of an online group intervention for posttraumatic growth (PTG) among Turkish women diagnosed with breast cancer: a pilot randomized controlled trial.","authors":"Cennet Yastibaş-Kaçar, Gülay Dirik, İmran Gökçen Yilmaz-Karaman","doi":"10.1080/13548506.2025.2575410","DOIUrl":"10.1080/13548506.2025.2575410","url":null,"abstract":"<p><p>Breast cancer is the most common cancer type among women, and it is a life-threatening disease. Although women with breast cancer may experience psychological distress, they may also experience posttraumatic growth (PTG). Therefore, this pilot study aimed to develop and test the effectiveness of an online group intervention focused on posttraumatic growth (PTGG) in women diagnosed with breast cancer. The sample of the randomized controlled trial consisted of 49 women with a mean age of 45.94 (7.57) years, ranging from 28 to 64 years, who were randomly assigned to eight weekly group sessions of PTGG, support groups (SG), and waitlist control groups (WLG). PTG, depression, anxiety, and stress scores were assessed at the pretest, posttest, and one-month follow-up. ANCOVA results indicated that PTGG was effective in promoting PTG on both the total and subscales and in reducing depression, compared with the other groups. These improvements were maintained at follow-up in favor of PTGG. However, no statistically significant differences were found between PTGG, SG, and WLG for anxiety and stress, indicating that no advantages were found in favor of either PTGG or SG. It was observed that the intervention effect was significant in analyses that included only clinically distressed individuals. Clinically depressed and anxious individuals in the PTGG reported greater improvements than those in the control group. Concerning these findings, our results also suggest that PTGG could be considered an effective online group intervention for distressed individuals with scores above the threshold, particularly for depression and anxiety. In conclusion, online PTGG can be used as an effective approach to enhance PTG and reduce psychological distress in women with breast cancer.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1693-1712"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David Kavuma, Ekwaro Anthony Obuku, Eve Namisango, Nixon Niyonzima, Alison Annet Kinengyere, Simon Kasasa, Fredrick Edward Makumbi, Rachel Kansiime, Hussein Mukasa Kafeero, Fred Nuwaha
{"title":"Effectiveness of psychosocial interventions in improving the quality of life for adult patients with cancer in low- and middle-income countries (LMICs): a systematic review and meta-analysis.","authors":"David Kavuma, Ekwaro Anthony Obuku, Eve Namisango, Nixon Niyonzima, Alison Annet Kinengyere, Simon Kasasa, Fredrick Edward Makumbi, Rachel Kansiime, Hussein Mukasa Kafeero, Fred Nuwaha","doi":"10.1080/13548506.2025.2587255","DOIUrl":"10.1080/13548506.2025.2587255","url":null,"abstract":"<p><p>Several systematic reviews have been published on psychosocial care interventions (PCIs) in cancer care. However, there are limited systematic reviews and meta-analyses (SRMA) on the effectiveness of PCIs in cancer care for adults patients in low- and-middle income countries (LMICs). This study aimed at synthesizing the available evidence on the effectiveness of PCI in improving the quality of life (QoL) of adult cancer patients in LMICs. We registered the protocol with PROSPERO (ID: CRD4202342156) before conducting this SRMA. Studies published between 2002 and 2023 were searched from MEDLINE, Web of Science, EmBASE and APA PsycINFO. We followed the standard guidelines for Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Results of the pooled studies were analysed using MedCalc version 10.10 statistical software. Twenty-six intervention studies were included in this SRMA. The Eastern Mediterranean WHO region had the highest number of studies and Africa region had the least. Most studies utilised Cognitive Behavioural therapy-related interventions (38%, <i>n</i> = 10 studies), while Family systems therapy 4% (<i>n</i> = 1) was the least utilised. From the subgroup analyses of the means and standard deviations of domains of QoL in the pooled primary studies, the respective standardized mean differences indicated that the PCIs had a significant positive effect on the physical (0.972: <i>p</i> = 0.002), social (0.884: <i>p</i> = 0.005) and psychological (0.590: <i>p</i> = 0.03) domains of QoL of adult cancer patients. However, some PCIs did not improve the QoL of study participants. Generally, PCIs effectively improved most domains of the QoL of adult cancer patients. However, more research is needed for PCIs that had a negative effect on some domains of the QoL of cancer patients. Lastly, there is need for LMICs to prioritise resources to strengthen the integration of psychosocial care interventions in cancer care to meet the different QoL sub-domains of patients with cancer.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1745-1793"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145670823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined psychological support and early enteral nutrition improve pain, sleep, and quality of life after colorectal cancer surgery: a randomized controlled trial.","authors":"Gang Wang, Shengjie Pan","doi":"10.1080/13548506.2025.2587973","DOIUrl":"10.1080/13548506.2025.2587973","url":null,"abstract":"<p><p>To evaluate the effects of combined psychological intervention and early enteral nutrition support on postoperative pain management, sleep quality, psychological well-being, and quality of life in colorectal cancer patients. A total of 320 colorectal cancer patients undergoing surgery were randomized into intervention (<i>n</i> = 160) and control (<i>n</i> = 160) groups. The intervention group received standard care plus psychological intervention and early enteral nutrition support, while the control group received standard care only. Outcomes were assessed pre- and post-intervention using the Pittsburgh Sleep Quality Index (PSQI), Visual Analog Scale (VAS) for pain, Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Compared with the control group, the intervention group showed significant improvements in sleep quality, pain intensity, anxiety, and depression scores (all <i>p</i> < 0.05). Quality of life scores measured by EORTC QLQ-C30 were also significantly higher in the intervention group (<i>p</i> < 0.05). Combined psychological intervention and early enteral nutrition significantly enhance postoperative symptom control, including pain relief, improved sleep, and better psychological health, resulting in an overall improvement in quality of life (QOL) for colorectal cancer patients. This integrated approach is a promising strategy for improving postoperative recovery and symptom management.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1794-1809"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abhijeet Kamble, Rangila Ram, Manish Sahore, And Narotam Ghezta
{"title":"Cultural influences on stigma and coping in Oral cancer patients: a cross-cultural perspective.","authors":"Abhijeet Kamble, Rangila Ram, Manish Sahore, And Narotam Ghezta","doi":"10.1080/13548506.2025.2575407","DOIUrl":"10.1080/13548506.2025.2575407","url":null,"abstract":"<p><strong>Background: </strong>Cultural beliefs shape how oral cancer patients perceive their illness, seek support, and manage psychological distress, particularly amid tobacco-related stigma. This study examines the role of cultural context in stigma, help-seeking behaviors, and mental health outcomes in oral squamous cell carcinoma (OSCC) patients, comparing rural and urban subcultures in India and referencing global literature.</p><p><strong>Materials and methods: </strong>We conducted a prospective study at H.P. Government Dental College and Hospital, Shimla, enrolling 56 OSCC patients from rural and urban backgrounds. We assessed psychological burden and quality of life using the Depression, Anxiety, and Stress Scale (DASS-21) and EORTC QLQ-H&N43 at diagnosis, two weeks, one month, and six months post-treatment. We analyzed data to identify correlations between stigma, subcultural context, mental health, and help-seeking behavior.</p><p><strong>Results: </strong>Rural patients reported significantly higher stigma and delayed help-seeking, associated with increased depression and stress over time. Urban patients exhibited proactive coping and better quality of life, despite similar tobacco-related stigma. Cross-cultural comparisons indicate that shame and stigma in tobacco-prevalent societies delay care and worsen psychological morbidity.</p><p><strong>Conclusion: </strong>Stigma rooted in cultural beliefs hinders timely diagnosis and psychological resilience in OSCC patients, especially in rural settings. Culturally sensitive psycho-oncology frameworks are needed to address stigma, promote mental health, and enhance help-seeking to improve oncologic and psychosocial outcomes.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1713-1722"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Addressing disparities: unmet health needs and its impact on health-related quality of life.","authors":"Birol Yetim, Özgür Uğurluoğlu","doi":"10.1080/13548506.2025.2512160","DOIUrl":"10.1080/13548506.2025.2512160","url":null,"abstract":"<p><p>This study focuses on unmet health needs in Türkiye and their effects on health-related quality of life. It also aims to examine how cardiovascular diseases influence individuals' quality of life. To achieve these objectives, data from the Türkiye Health Surveys, conducted by Turkish Statistical Institute, were analyzed. The study sample of individuals aged 18 and over. After excluding incomplete responses, a total of 70 000 observations were included in the analysis. To assess the quality of life, 15 questions from the surveys were selected based on their compatibility with the EQ-5D-3 L scale. The validity and reliability of these items were tested through factor analysis. Descriptive statistics, t-tests and regression models were used to analyze the data. The findings revealed that unmet health needs significantly reduce health-related quality of life. Individuals who could not access healthcare services due to financial difficulties, transportation issues or long waiting times reported lower quality of life scores. Furthermore, women, individuals with lower educational attainment and income levels and those diagnosed with cardiovascular diseases were found to have significantly lower quality of life. The study concludes that unmet health needs remain a critical health concern in Türkiye, especially among disadvantaged and chronically ill populations. It is recommended that policymakers prioritize strategies to reduce financial and systemic barriers in healthcare access. Increasing educational and economic opportunities and enhancing support for patients with chronic diseases could contribute to improving overall health outcomes. Addressing these disparities will help align the healthcare system with the evolving needs of the population and promote a more equitable approach to health service delivery.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1920-1935"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between emotional adjustment and depressive symptoms in women with breast cancer.","authors":"Mahsa Ebadi, Farshad Mohammadi, Bita Ebadi, Moloud Radfar, Parvin Hassanzadeh","doi":"10.1080/13548506.2025.2594175","DOIUrl":"10.1080/13548506.2025.2594175","url":null,"abstract":"<p><p>Breast cancer is a prevalent health issue globally, often accompanied by psychological distress such as depressive symptoms. This study investigated the relationship between emotional adjustment and depressive symptoms in 120 women with stage I to III breast cancer attending hospitals affiliated with Urmia University of Medical Sciences. Participants were at least six months post-treatment, literate, and free from other chronic illnesses or psychiatric conditions. Data were collected using demographic questionnaires, the Emotional Adjustment Questionnaire, and the KDS-II depressive symptoms scale. Results showed a significant positive correlation between emotional adjustment and depressive symptoms (<i>r</i> = 0.30, <i>p</i> = 0.001). Multiple regression revealed emotional adjustment as a significant predictor of depressive symptom severity (β = 0.20). Employment status and age were also associated with depressive symptoms. These findings suggest that maladaptive emotional adjustment may increase depressive symptoms, highlighting the importance of psychological interventions to enhance emotional coping and improve mental health in women with breast cancer.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1810-1822"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145607538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Madeline J Plummer, Rose Ann DiMaria-Ghalili, Ana Maria Lopez, Carolyn Y Fang, Christopher L Coe, Agus Surachman
{"title":"Educational attainment, health locus of control and inflammation among cancer survivors in the Midlife in the United States (MIDUS) study.","authors":"Madeline J Plummer, Rose Ann DiMaria-Ghalili, Ana Maria Lopez, Carolyn Y Fang, Christopher L Coe, Agus Surachman","doi":"10.1080/13548506.2025.2581230","DOIUrl":"10.1080/13548506.2025.2581230","url":null,"abstract":"<p><p>The goal of this study was to investigate whether HLOC mediates the relationship between educational attainment and inflammatory proteins in cancer survivors. Data are from 298 cancer survivors (87.54% white; <i>M</i> age = 63.6; <i>M</i> survivorships = 15 years) who participated in the Biomarker protocol of Wave 2 and Refresher phases of the Midlife in the United States (MIDUS) study. Educational attainment was dichotomized (bachelor's degree or above versus lower). The two measures of HLOC were based on whether participants felt others had control over their health outcomes (external HLOC) or if they felt they were in control of their health outcomes (internal HLOC). We used C-reactive protein (CRP) and interleukin-6 (IL-6) as markers of inflammation. Mediation analyses for external and internal HLOC were tested separately. Mediation analyses were conducted using the PROCESS package in R (using 10 000 bootstrapped samples). Analyses were adjusted for age, sex, cohort, body mass index (BMI), smoking status, and race/ethnicity. In the fully adjusted model, educational attainment and external HLOC were significantly associated with CRP. Relative to those with bachelor's degrees, participants with lower educational attainment had elevated CRP (<i>b</i> = -0.25, <i>SE</i> = 0.11, 95% <i>CI</i> = [-0.47, -0.03]). Higher external HLOC was linked to increased CRP (<i>b</i> = 0.10, <i>SE</i> = 0.04, 95% <i>CI</i> = [0.01, 0.18]). The mediation analyses showed that a higher external HLOC was a significant path through which lower educational attainment was associated with elevated CRP (indirect effect = -0.05, bootstrapped <i>SE</i> = 0.02, 95% <i>CI</i> [bootstrapped] = [-0.10, -0.01]. Cancer survivors with lower educational attainment may tend to perceive that their health is outside of their control. These socioeconomic and psychosocial processes may drive an increase in the circulating levels of inflammatory signaling proteins known to be sensitive predictors of age-related chronic diseases.</p>","PeriodicalId":54535,"journal":{"name":"Psychology Health & Medicine","volume":" ","pages":"1723-1744"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145395190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}