EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-D-24-01102
Maximilian Will, Gregor Leibundgut, Konstantin Schwarz
{"title":"Intravascular lithotripsy for proximal cap ambiguity in percutaneous coronary intervention for chronic total occlusions: the \"stone whisper\" technique.","authors":"Maximilian Will, Gregor Leibundgut, Konstantin Schwarz","doi":"10.4244/EIJ-D-24-01102","DOIUrl":"10.4244/EIJ-D-24-01102","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e769-e770"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-D-24-01003
Xiang Chen, Giulio Russo, Mi Chen, Zhu Da, Xiangbin Pan, Yan Wang, Edwin Ho, Emiliano Votta, Paolo Denti, Didier Tchétché, Azeem Latib, Maurizio Taramasso
{"title":"Current and future applications of robotics in structural heart interventions.","authors":"Xiang Chen, Giulio Russo, Mi Chen, Zhu Da, Xiangbin Pan, Yan Wang, Edwin Ho, Emiliano Votta, Paolo Denti, Didier Tchétché, Azeem Latib, Maurizio Taramasso","doi":"10.4244/EIJ-D-24-01003","DOIUrl":"10.4244/EIJ-D-24-01003","url":null,"abstract":"<p><p>Robotics entered the cardiovascular field in the late 1990s with a robot-assisted coronary artery bypass graft. Since then, the use of robots has become a common part of cardiovascular surgery in several types of interventions. The experience in transcatheter interventions has been slower, and the application of robotics to percutaneous coronary interventions has shown some encouraging results but also some technical limitations. Following the growth of structural heart interventions, attention has recently switched to the potential application of robotics in this field. So far, several cases have been performed in animal models and only a few cases in humans. The opportunity to perform a procedure (almost) without any X-ray exposure or lead garments is extremely attractive, especially for operators. Alongside these, there are several further potential advantages, but there are also many challenges to overcome. The integration of artificial intelligence and machine learning in the near future might further contribute to improve the performance of future generations of robots. In this review, the current and future applications of robotics in structural heart interventions and transoesophageal echocardiography will be discussed, together with the potential advantages, challenges and future perspectives.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e727-e736"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-E-25-00027
George Dangas, Johny Nicolas
{"title":"Antithrombotic strategies after TAVI in light of cerebral microembolism.","authors":"George Dangas, Johny Nicolas","doi":"10.4244/EIJ-E-25-00027","DOIUrl":"10.4244/EIJ-E-25-00027","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e716-e717"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-E-25-00019
Kevin R Bainey, Xavier Rossello
{"title":"Colchicine benefits are overestimated and current recommendations are too strong: pros and cons.","authors":"Kevin R Bainey, Xavier Rossello","doi":"10.4244/EIJ-E-25-00019","DOIUrl":"10.4244/EIJ-E-25-00019","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e723-e726"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-E-25-00028
Liesbeth Rosseel, Arif A Khokhar, Ole De Backer
{"title":"The challenge of interpreting comparative TAVI studies.","authors":"Liesbeth Rosseel, Arif A Khokhar, Ole De Backer","doi":"10.4244/EIJ-E-25-00028","DOIUrl":"10.4244/EIJ-E-25-00028","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e718-e719"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-E-25-00024
Philippe Pibarot, Eric Van Belle
{"title":"The new balloon-expandable Myval transcatheter heart valve: only good news?","authors":"Philippe Pibarot, Eric Van Belle","doi":"10.4244/EIJ-E-25-00024","DOIUrl":"10.4244/EIJ-E-25-00024","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e720-e722"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207331/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-D-24-00872
Victor Alfonso Jimenez Diaz, Pablo Juan-Salvadores, Paula Bellas Lamas, Mercedes Arias Gonzalez, Eloisa Santos Armentia, Oscar Vila Nieto, Carmen Gonzalez Mao, Tamara Torrado Chedas, Antonio Jesus Muñoz Garcia, Ivan Gomez Blazquez, Guillermo Bastos Fernandez, Antonio De Miguel Castro, Saleta Fernandez Barbeira, Alberto Ortiz Saez, Jose Antonio Baz Alonso, Juan Ocampo Miguez, Lucia Rioboo Leston, Pablo Pazos Lopez, Francisco Calvo Iglesias, Angel Salgado Barreira, Carlos Maria Diaz Lopez, Adolfo Figueiras, Cesar Veiga Garcia, Andres Iñiguez Romo
{"title":"A comparison of antiplatelet and oral anticoagulation strategies to prevent cerebral microembolism after transcatheter aortic valve implantation: the AUREA trial.","authors":"Victor Alfonso Jimenez Diaz, Pablo Juan-Salvadores, Paula Bellas Lamas, Mercedes Arias Gonzalez, Eloisa Santos Armentia, Oscar Vila Nieto, Carmen Gonzalez Mao, Tamara Torrado Chedas, Antonio Jesus Muñoz Garcia, Ivan Gomez Blazquez, Guillermo Bastos Fernandez, Antonio De Miguel Castro, Saleta Fernandez Barbeira, Alberto Ortiz Saez, Jose Antonio Baz Alonso, Juan Ocampo Miguez, Lucia Rioboo Leston, Pablo Pazos Lopez, Francisco Calvo Iglesias, Angel Salgado Barreira, Carlos Maria Diaz Lopez, Adolfo Figueiras, Cesar Veiga Garcia, Andres Iñiguez Romo","doi":"10.4244/EIJ-D-24-00872","DOIUrl":"10.4244/EIJ-D-24-00872","url":null,"abstract":"<p><strong>Background: </strong>The effectiveness of oral anticoagulation (OAC) or dual antiplatelet therapy (DAPT) in reducing subclinical brain infarcts after transcatheter aortic valve implantation (TAVI) remains unclear.</p><p><strong>Aims: </strong>We aimed to compare the efficacy of DAPT versus OAC in preventing cerebral microembolism during the first 3 months post-TAVI, assessed by diffusion-weighted magnetic resonance imaging (DW-MRI).</p><p><strong>Methods: </strong>Patients with aortic stenosis and no indication for OAC were randomly assigned to receive either OAC (acenocoumarol) or DAPT (aspirin+clopidogrel) for 3 months post-TAVI. Brain DW-MRI was performed at baseline (0-3 days pre-TAVI) and at 6 and 90 days post-TAVI. The primary objective was the proportion of patients with new cerebral emboli on DW-MRI at 6 and 90 days.</p><p><strong>Results: </strong>Of the 123 patients included in the study, 3.3% had new cerebral emboli on the baseline MRI prior to TAVI. At 6 days post-TAVI, new cerebral emboli were observed in 81.4% of OAC patients versus 69.8% of DAPT patients (p=0.209), and at 90 days, in 8.0% versus 8.2%, respectively (p=0.879). However, DAPT patients had a lower mean total emboli volume at 6 days (265.9 mm³ vs 303.4 mm³; p=0.019) and cumulatively at 6+90 days (266.45 mm³ vs 331.10 mm³; p=0.008).</p><p><strong>Conclusions: </strong>In patients without an indication for OAC, an OAC strategy for 3 months post-TAVI did not show any benefit over an antiplatelet strategy in preventing cerebral microembolism. Patients treated with DAPT showed a lower mean volume of brain damage on DW-MRI during the 90 days following TAVI compared to those treated with acenocoumarol.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e737-e748"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12230756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-07-07DOI: 10.4244/EIJ-D-24-01112
Akash Jain, John Jose, Matteo Montorfano, Henrik Nissen, Pedro Martin, Ashok Seth, Kresimir Stambuk, Gunasekaran Sengottuvelu, Mussayev Abdurashid, Mario García-Gómez, Clara Fernandez-Cordón, Marcelo Rodriguez, Mathias D Jorgensen, Alberto Campo, Ana Serrador, Silvia Vallinas-Hernandez, Manuel Carrasco-Moraleja, Alberto San Román, Ignacio J Amat-Santos
{"title":"Four-year durability of the Myval balloon-expandable transcatheter aortic valve.","authors":"Akash Jain, John Jose, Matteo Montorfano, Henrik Nissen, Pedro Martin, Ashok Seth, Kresimir Stambuk, Gunasekaran Sengottuvelu, Mussayev Abdurashid, Mario García-Gómez, Clara Fernandez-Cordón, Marcelo Rodriguez, Mathias D Jorgensen, Alberto Campo, Ana Serrador, Silvia Vallinas-Hernandez, Manuel Carrasco-Moraleja, Alberto San Román, Ignacio J Amat-Santos","doi":"10.4244/EIJ-D-24-01112","DOIUrl":"10.4244/EIJ-D-24-01112","url":null,"abstract":"<p><strong>Background: </strong>The Myval series is the first commercially available balloon-expandable transcatheter aortic valve implantation (TAVI) system designed as an alternative to the SAPIEN series. The LANDMARK trial recently demonstrated its non-inferiority compared to contemporary systems. However, the long-term durability of the Myval series remains unknown.</p><p><strong>Aims: </strong>We aimed to evaluate the 4-year durability of the Myval series using Valve Academic Research Consortium (VARC)-3-defined endpoints.</p><p><strong>Methods: </strong>We carried out a multicentre ambispective study of patients with severe aortic stenosis who underwent TAVI with the Myval series between December 2017 and April 2020. Baseline characteristics were prospectively recorded in a dedicated database. Clinical and echocardiographic follow-up was performed at 4 years. Outcomes included haemodynamic valve deterioration (HVD), bioprosthetic valve failure (BVF), and patient-prosthesis mismatch (PPM) as defined by the VARC-3 criteria, assessed at a central echocardiography laboratory.</p><p><strong>Results: </strong>A total of 366 patients from 9 institutions were included, all of whom completed 4-year follow-up or were followed up until death. The 4-year survival rate was 81.8%, with residual ≥moderate aortic regurgitation observed in 9.2% of patients. BVF criterion 1 (symptomatic valve failure) occurred in 3.3%, while no cases of BVF criteria 2 or 3 were reported. Stage 2 HVD was observed in 9.7% of patients and stage 3 HVD in 0.7% at 4 years. Moderate and severe PPM were identified in 3.6% and 2.1% of patients at 1 year, respectively.</p><p><strong>Conclusions: </strong>In a real-world cohort, 4-year outcomes with the balloon-expandable Myval series demonstrated acceptable valve durability, low haemodynamic deterioration, and comparable performance to contemporary TAVI systems.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 13","pages":"e758-e765"},"PeriodicalIF":7.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
EurointerventionPub Date : 2025-06-16DOI: 10.4244/EIJ-D-24-00876
Valeria Paradies, Giulia Masiero, Andrea Rubboli, Heleen M M Van Beusekom, Francesco Costa, Piera Capranzano, Sophie Degrauwe, Diana A Gorog, Claudia Moreira Jorge, Gill Louise Buchanan, Mirvat Alasnag, Daniela Trabattoni, Chiara Fraccaro, Dirk Sibbing, Dariusz Dudek, Gemma Vilahur, Alaide Chieffo, Roxana Mehran, Davide Capodanno, Emanuele Barbato, Jolanta M Siller-Matula
{"title":"Antithrombotic drugs for acute coronary syndromes in women: sex-adjusted treatment and female representation in randomised clinical trials. A clinical consensus statement of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) and the ESC Working Group on Thrombosis.","authors":"Valeria Paradies, Giulia Masiero, Andrea Rubboli, Heleen M M Van Beusekom, Francesco Costa, Piera Capranzano, Sophie Degrauwe, Diana A Gorog, Claudia Moreira Jorge, Gill Louise Buchanan, Mirvat Alasnag, Daniela Trabattoni, Chiara Fraccaro, Dirk Sibbing, Dariusz Dudek, Gemma Vilahur, Alaide Chieffo, Roxana Mehran, Davide Capodanno, Emanuele Barbato, Jolanta M Siller-Matula","doi":"10.4244/EIJ-D-24-00876","DOIUrl":"10.4244/EIJ-D-24-00876","url":null,"abstract":"<p><p>Thrombotic and bleeding risks differ between sexes, partly in relation to distinct biology and hormonal status, but also due to differences in age, comorbidities, and body size at presentation. Women experience frequent fluctuations of prothrombotic and bleeding status related to menstrual cycle, use of oral contraceptives, hormone replacement therapy, or menopause. Although clinical studies tend to underrepresent women, available data consistently support sex-specific differences in the baseline thrombotic and haemorrhagic risks. Compared with men, women feature an increased risk of in-hospital bleeding related to invasive procedures, as well as long-term out-of-hospital bleeding events. In addition, the inappropriate dosing of antithrombotic drugs, which is not adapted to body weight or renal function, is more frequently associated with an increased risk of bleeding in women compared to men. While acute coronary syndrome (ACS) studies support similar antithrombotic drug efficacy, irrespective of sex, women may receive delayed treatment due to bias in their referral, diagnosis, and invasive treatment decisions. The current clinical consensus statement highlights the need for an increased awareness of sex-specific risks and biases in ACS management, with a focus on sex-specific bleeding mitigation strategies, antithrombotic management in special conditions (e.g., myocardial infarction with non-obstructive coronary arteries), and barriers to female representation in cardiovascular trials. This manuscript aims to provide expert opinion, based on the best available evidence, and consensus statements on optimising antithrombotic therapy according to sex, which is critical to improve sex-based disparities in outcome.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":" ","pages":"e655-e667"},"PeriodicalIF":7.6,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12151167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}