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Paclitaxel- or sirolimus-coated balloons for coronary bifurcations: is the side branch SPACIOUS enough for both?
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-17 DOI: 10.4244/EIJ-E-25-00004
Daniele Giacoppo
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引用次数: 0
Final kissing balloon dilatation in patients with coronary bifurcation lesions treated with an upfront provisional stenting strategy.
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-17 DOI: 10.4244/EIJ-D-24-00471
Ovidio De Filippo, Jeehoon Kang, Francesco Bruno, Young Bin Song, Salvatore Campagnuolo, Ki Hong Choi, Tineke H Pinxterhuis, Hyun Kuk Kim, Alessio Mattesini, Yun-Kyeong Cho, Raffaele Piccolo, Hyun-Jong Lee, Wojciech Wańha, Bernardo Cortese, Seung Hwan Han, Leor Perl, Seung-Ho Hur, Domenico Tuttolomondo, Mario Iannaccone, Woo Jung Chun, Antonio Greco, Attilio Leone, Alessandra Truffa Giachet, Hyeon-Cheol Gwon, Giulio Stefanini, Hyo-Soo Kim, Javier Escaned, Antonino Carmeci, Gianluca Campo, Giuseppe Patti, Davide Capodanno, Clemens von Birgelen, Bon-Kwon Koo, Gaetano Maria de Ferrari, Chang-Wook Nam, Fabrizio D'Ascenzo
{"title":"Final kissing balloon dilatation in patients with coronary bifurcation lesions treated with an upfront provisional stenting strategy.","authors":"Ovidio De Filippo, Jeehoon Kang, Francesco Bruno, Young Bin Song, Salvatore Campagnuolo, Ki Hong Choi, Tineke H Pinxterhuis, Hyun Kuk Kim, Alessio Mattesini, Yun-Kyeong Cho, Raffaele Piccolo, Hyun-Jong Lee, Wojciech Wańha, Bernardo Cortese, Seung Hwan Han, Leor Perl, Seung-Ho Hur, Domenico Tuttolomondo, Mario Iannaccone, Woo Jung Chun, Antonio Greco, Attilio Leone, Alessandra Truffa Giachet, Hyeon-Cheol Gwon, Giulio Stefanini, Hyo-Soo Kim, Javier Escaned, Antonino Carmeci, Gianluca Campo, Giuseppe Patti, Davide Capodanno, Clemens von Birgelen, Bon-Kwon Koo, Gaetano Maria de Ferrari, Chang-Wook Nam, Fabrizio D'Ascenzo","doi":"10.4244/EIJ-D-24-00471","DOIUrl":"10.4244/EIJ-D-24-00471","url":null,"abstract":"<p><strong>Background: </strong>The impact of final kissing balloon inflation (FKB) in patients treated with an upfront provisional strategy for coronary bifurcation lesions is controversial.</p><p><strong>Aims: </strong>We aimed to assess the impact of FKB on patient- and lesion-oriented outcomes in a large real-world cohort.</p><p><strong>Methods: </strong>The ULTRA-BIFURCAT registry was obtained by patient-level merging the BIFURCAT and ULTRA registries. Pairs of patients were generated with propensity score matching (PSM). The primary outcome of interest was major adverse cardiac events (MACE) - a composite of all-cause death, myocardial infarction (MI), target lesion revascularisation (TLR) or stent thrombosis. A lesion-oriented composite outcome (LOCO) - a composite of target vessel MI (TVMI) or TLR - along with each single component of MACE represented the secondary outcomes. Subgroup analyses included the site of bifurcation (unprotected left main [ULM] vs non-ULM), side branch involvement (true bifurcation vs non-true bifurcation), side branch diameter and lesion length. Follow-up was censored at 800 days.</p><p><strong>Results: </strong>A total of 5,607 patients undergoing a provisional stenting technique were selected for the present analysis. PSM generated 1,784 pairs. Between the matched patients with FKB versus no FKB, no significant difference in MACE was observed (9.0% vs 8.6%; p=0.68). FKB was associated with a lower rate of the LOCO (1.9% vs 2.9%; p=0.04) compared to the no FKB group, driven by lower rates of TVMI (0.2% vs 0.5%; p=0.03) and TLR (1.8% vs 2.6%; p=0.14). These results were confirmed in the subgroups of patients treated for bifurcations with side branches with a diameter >2.5 mm and for true coronary bifurcation lesions.</p><p><strong>Conclusions: </strong>Among patients treated for coronary bifurcation lesions with provisional stenting, FKB had no significant impact on MACE but was associated with a mild reduction in the incidence of the LOCO.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 6","pages":"e318-e328"},"PeriodicalIF":7.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11895841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LETTER: An update on changes to the design of the ODIN trial.
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-17 DOI: 10.4244/EIJ-D-24-00974
Sigrid Sandner, Björn Redfors, Marc Ruel, Mario Gaudino
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引用次数: 0
Routine diagnosis of ANOCA/INOCA: pros and cons.
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-17 DOI: 10.4244/EIJ-E-24-00072
Rocco Antonio Montone, Andrea Caffè, Keisuke Yasumura, Annapoorna Kini
{"title":"Routine diagnosis of ANOCA/INOCA: pros and cons.","authors":"Rocco Antonio Montone, Andrea Caffè, Keisuke Yasumura, Annapoorna Kini","doi":"10.4244/EIJ-E-24-00072","DOIUrl":"10.4244/EIJ-E-24-00072","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 6","pages":"e293-e295"},"PeriodicalIF":7.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling the coronary acetylcholine test: can it help us predict future cardiovascular events?
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-17 DOI: 10.4244/EIJ-E-25-00005
Javier Escaned, Luca Paolucci
{"title":"Unveiling the coronary acetylcholine test: can it help us predict future cardiovascular events?","authors":"Javier Escaned, Luca Paolucci","doi":"10.4244/EIJ-E-25-00005","DOIUrl":"10.4244/EIJ-E-25-00005","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 6","pages":"e288-e289"},"PeriodicalIF":7.6,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11891918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CIED and tricuspid regurgitation - a LEADing problem?
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-03 DOI: 10.4244/EIJ-E-24-00061
Martin Andreas, Philipp Emmanuel Bartko, Andreas Zirlik
{"title":"CIED and tricuspid regurgitation - a LEADing problem?","authors":"Martin Andreas, Philipp Emmanuel Bartko, Andreas Zirlik","doi":"10.4244/EIJ-E-24-00061","DOIUrl":"10.4244/EIJ-E-24-00061","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e245-e246"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849530/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcomes of tricuspid transcatheter edge-to-edge repair in subjects with endocardial leads.
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-03 DOI: 10.4244/EIJ-D-23-01033
Björn Goebel, Philipp Lurz, Thomas Schmitz, Raffi Bekeredjian, Georg Nickenig, Helge Mollmann, Ralph Stephan von Bardeleben, Alexander Schmeisser, Megan Heitkemper, Iskandar Atmowihardjo, Rodrigo Estévez-Loureiro, Erwan Donal
{"title":"Outcomes of tricuspid transcatheter edge-to-edge repair in subjects with endocardial leads.","authors":"Björn Goebel, Philipp Lurz, Thomas Schmitz, Raffi Bekeredjian, Georg Nickenig, Helge Mollmann, Ralph Stephan von Bardeleben, Alexander Schmeisser, Megan Heitkemper, Iskandar Atmowihardjo, Rodrigo Estévez-Loureiro, Erwan Donal","doi":"10.4244/EIJ-D-23-01033","DOIUrl":"10.4244/EIJ-D-23-01033","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter edge-to-edge repair (TEER) using the TriClip tricuspid valve repair system has emerged as a therapy for tricuspid regurgitation (TR). Patients with TR undergoing TEER commonly present with an endocardial lead across the tricuspid valve (TV).</p><p><strong>Aims: </strong>We sought to examine the effectiveness and safety of tricuspid TEER (T-TEER) in subjects with endocardial leads in the bRIGHT EU Post-Approval Study (PAS).</p><p><strong>Methods: </strong>The bRIGHT EU PAS is a prospective, single-arm, open-label, multicentre, post-market registry conducted at 26 sites in Europe. Echocardiographic assessments of endocardial lead placement, interaction, and TR grade were performed at a core laboratory.</p><p><strong>Results: </strong>Of the 511 enrolled subjects, a total of 110 had an endocardial lead, and in 80.7% of these subjects, TR was at least partially related to the lead. At 30 days, 71% of subjects with endocardial leads had TR of moderate or less. The percentage of subjects with endocardial leads categorised as New York Heart Association Functional Class I-II increased from 17% at baseline to 75% at 30 days (p<0.0001), and quality of life with the Kansas City Cardiomyopathy Questionnaire showed a mean improvement of 20±24 points from baseline to 30 days (p<0.0001). T-TEER was safe in subjects with endocardial leads, with similar rates of events, including TV reintervention/reoperation and TV surgery, to those in subjects without leads. No reports of lead malfunction were reported.</p><p><strong>Conclusions: </strong>In the bRIGHT EU PAS, T-TEER using the TriClip system was safe and effective in severe TR subjects with an endocardial lead across the TV.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e253-e261"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double mitral and tricuspid transcatheter valve replacement.
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-03 DOI: 10.4244/EIJ-D-24-00816
Guillaume Leurent, Guillaume L'Official, Amedeo Anselmi, Erwan Donal, Vincent Auffret
{"title":"Double mitral and tricuspid transcatheter valve replacement.","authors":"Guillaume Leurent, Guillaume L'Official, Amedeo Anselmi, Erwan Donal, Vincent Auffret","doi":"10.4244/EIJ-D-24-00816","DOIUrl":"10.4244/EIJ-D-24-00816","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e285-e286"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849528/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter annuloplasty with the K-Clip system for tricuspid regurgitation: one-year results from the TriStar study.
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-03 DOI: 10.4244/EIJ-D-24-00591
Xiaochun Zhang, Qinchun Jin, Wei Li, Cuizhen Pan, Kefang Guo, Xue Yang, Weidong Li, Guangyuan Song, Jiangfang Luo, Jie Li, Xianbao Liu, Shasha Chen, Lei Zhang, Dandan Chen, Shiqiang Hou, Juying Qian, Jianan Wang, Daxin Zhou, Junbo Ge
{"title":"Transcatheter annuloplasty with the K-Clip system for tricuspid regurgitation: one-year results from the TriStar study.","authors":"Xiaochun Zhang, Qinchun Jin, Wei Li, Cuizhen Pan, Kefang Guo, Xue Yang, Weidong Li, Guangyuan Song, Jiangfang Luo, Jie Li, Xianbao Liu, Shasha Chen, Lei Zhang, Dandan Chen, Shiqiang Hou, Juying Qian, Jianan Wang, Daxin Zhou, Junbo Ge","doi":"10.4244/EIJ-D-24-00591","DOIUrl":"10.4244/EIJ-D-24-00591","url":null,"abstract":"<p><strong>Background: </strong>Despite the fact that morbidity and mortality rates significantly increase with tricuspid regurgitation (TR) severity, limited treatment options are available for treating severe TR.</p><p><strong>Aims: </strong>The single-arm, multicentre, prospective Confirmatory Clinical Study of Treating Tricuspid Regurgitation With K-Clip TM Transcatheter Annuloplasty System (TriStar) evaluated the 1-year outcomes of the novel transcatheter K-Clip annuloplasty system in treating secondary TR.</p><p><strong>Methods: </strong>Between May 2022 and October 2022, patients with ≥severe secondary TR despite optimal medical therapy at 11 centres in China were deemed candidates for transcatheter tricuspid repair by the local Heart Team and a multidisciplinary screening committee. Echocardiographic parameters, clinical and quality-of-life measures, and major adverse events were collected at 1 year.</p><p><strong>Results: </strong>Ninety-six patients were enrolled (mean age 72.6±7.0 years, 60.4% female, mean TRI-SCORE 5.4±2.1). The technical success rate was 97.9%. At 1 year, echocardiographic follow-up showed an average reduction in the annular septolateral diameter of 11.3% (41.9 mm vs 37.1 mm; p<0.01), compared with baseline, with marked right ventricular remodelling. A total of 82.5% of patients had ≤moderate TR, and 97.7% had a ≥1 grade reduction. Patients experienced significant clinical improvements in New York Heart Association Functional Class I/II (32.6% to 96.5%; p<0.001), the 6-minute walk distance increased by 31.9±71.8 m (p<0.001), and the overall Kansas City Cardiomyopathy Questionnaire score increased by 7.6±17.7 points (p<0.001). Neither cardiovascular death nor reintervention were recorded at the 30-day or 1-year follow-up, while severe bleeding requiring further treatment was noted in 5 patients at 1 year. The Kaplan-Meier estimates of survival and freedom from heart failure rehospitalisation were 97.8% and 95.1%, respectively, at 1 year.</p><p><strong>Conclusions: </strong>The 1-year experience using the K-Clip tricuspid annuloplasty system demonstrated high survival and low rehospitalisation rates with durable TR reduction and clinical benefits in functional status and quality-of-life outcomes.</p>","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e262-e271"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tricuspid annuloplasty: a piece of the puzzle or the whole picture?
IF 7.6 1区 医学
Eurointervention Pub Date : 2025-03-03 DOI: 10.4244/EIJ-E-25-00006
Georg Nickenig, Johanna Vogelhuber
{"title":"Tricuspid annuloplasty: a piece of the puzzle or the whole picture?","authors":"Georg Nickenig, Johanna Vogelhuber","doi":"10.4244/EIJ-E-25-00006","DOIUrl":"10.4244/EIJ-E-25-00006","url":null,"abstract":"","PeriodicalId":54378,"journal":{"name":"Eurointervention","volume":"21 5","pages":"e247-e249"},"PeriodicalIF":7.6,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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