{"title":"Cover Picture: Fast and Stable Cycling of 2,6-Diaminoanthraquinone as a Redox-Active Organic Cathode for Sodium-Ion Batteries (BKCS 7/2025) Honggyu Seong, Youngseok Chang, Jaewon Choi","authors":"","doi":"10.1002/bkcs.12868","DOIUrl":"https://doi.org/10.1002/bkcs.12868","url":null,"abstract":"<p>The cover image illustrates the Na<sup>+</sup>-ion storage capabilities of commercially available 2,6-diaminoanthraquinone (2,6-DAAQ) as a redox-active organic cathode material for advanced sodium-ion batteries, highlighting its fast rechargeability and excellent cycling stability. 2,6-DAAQ employs its redox-active carbonyl groups to enable durable cycling performance through a reversible sodiation and desodiation process. More detailed insights into the Na<sup>+</sup>-ion storage behavior of the 2,6-DAAQ cathode can be found in the article by Honggyu Seong, Youngseok Chang, and Jaewon Choi. Details are in the article by Honggyu Seong, Youngseok Chang, Jaewon Choi.\u0000\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.12868","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Excited-state proton transfer of weak and medium-strength photoacids in confined methanol-in-oil reverse micelles","authors":"Taehyung Jang, Yoonsoo Pang","doi":"10.1002/bkcs.70034","DOIUrl":"https://doi.org/10.1002/bkcs.70034","url":null,"abstract":"<p>This study explores the excited-state proton transfer (ESPT) dynamics of weak and medium-strength photoacids, 8-hydroxypyrene-1,3,6-trisulfonic trisodium salt (pyranine; HPTS), D-luciferin, and 2-cyano-6-hydroxybenzothiazole (CBTOH), confined within <i>water-in-oil</i> and <i>methanol-in-oil</i> reverse micelles (RMs). We extend the previous work on the ESPT dynamics of HPTS in Igepal RMs to several weak or medium-strength photoacids confined in the RMs. These photoacids exhibit proton transfer rate constants on the order of 10<sup>9</sup> s<sup>−1</sup> in small RMs, which are comparable to the solvation dynamics inside the RMs. This suggests that the solvation dynamics govern the ESPT rates in the RMs, irrespective of the core polar solvent characteristics.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"658-665"},"PeriodicalIF":1.7,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Landep Ayuningtias, Jae Yeol Ma, Yu-Jin Kim, Yun-Hi Kim
{"title":"Synthesis and characterization of diketopyrrolopyrrole-based conjugated polymer with biphenyl for organic photovoltaic cells","authors":"Landep Ayuningtias, Jae Yeol Ma, Yu-Jin Kim, Yun-Hi Kim","doi":"10.1002/bkcs.70042","DOIUrl":"https://doi.org/10.1002/bkcs.70042","url":null,"abstract":"<p>Designing a moderate band gap is sometimes intentionally chosen. When the donor polymer has a deeper HOMO level, a higher Voc can be gained which boosts total PCE in organic photovoltaics (OPVs) (Liao et al., <i>Joule</i> <b>2020</b>, <i>4</i>(1), 189–206; Mamba et al., <i>J. Phys. Chem. A</i> <b>2021</b>, <i>125</i>(50), 10593–10603; Choi and Jo, <i>Org. Electron.</i> <b>2013</b>, <i>14</i>(6), 1621–1628; Jo et al., <i>Org. Electron.</i> <b>2012</b>, <i>13</i>(10), 2185–2191). This is crucial in DPP-based copolymer frameworks, which frequently have short band gaps and may experience poor Voc. Since DPP is a low bandgap due to strong-acceptor, thus, modifying it with weak donor units can raise the bandgap and lower the HOMO to make it suitable for multi-junctions or higher Voc. We report the synthesis, properties, and photovoltaic applications of a donor-acceptor (D-A) conjugated copolymer based on diketopyrrolopyrrole (DPP) and biphenyl, namely PDDPPhenyl. This polymer exhibits broad absorption ranging from 400 to 900 nm with a band gap of 1.59 eV. As expected, a low HOMO level of −5.29 was gained by introducing biphenyl as a weaker donor. The optimized weight ratio goes to 1:4 for PDPPPhenyl:PC<sub>71</sub>BM with 3.8% PCE.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"754-760"},"PeriodicalIF":1.7,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nonvide Nicolas Adiko, Hyeon Tae Seo, Dae-Won Ki, Jung Hee Park, Da Som Kim
{"title":"Insight into the functional and structural relationship of ornithine decarboxylase and its mutants from Lacticaseibacillus rhamnosus","authors":"Nonvide Nicolas Adiko, Hyeon Tae Seo, Dae-Won Ki, Jung Hee Park, Da Som Kim","doi":"10.1002/bkcs.70035","DOIUrl":"https://doi.org/10.1002/bkcs.70035","url":null,"abstract":"<p>Ornithine decarboxylase (ODC) is a critical enzyme in the polyamine biosynthesis pathway that catalyzes the conversion of <span>l</span>-ornithine to putrescine using pyridoxal 5′-phosphate (PLP). Lactobacilli act probiotically by stimulating the immune system, defending against pathogens, and mitigating the impact of various chronic illnesses. To better understand the function and structure of ODC from <i>Lacticaseibacillus rhamnosus</i> (LrODC-WT), we investigated its enzymatic activity, kinetic characteristics, crystal structure, and further examined a variety of single-residue mutants. We found that active LrODC-WT has the following kinetic parameters: <i>K</i><sub>M</sub> 6.83 ± 1.01 mM, <i>k</i><sub>cat</sub> 1.44 ± 0.1 s<sup>−1</sup>, and <i>k</i><sub>cat</sub>/<i>K</i><sub>M</sub> 210.83 ± 19.37 M<sup>−1</sup> s<sup>−1</sup>. Unlike LrODC-WT, H346A, F186A, H216F, and E281Q showed no catalytic activity. H346A showed maximum unfolding at 2 M guanidine hydrochloride (GdnHCl), while the other enzymes exhibited peak unfolding effects at 1 M, indicating that H346A shows higher resistance to GdnHCl. The PLP binding in LrODCs using a UV/Vis spectrometer showed that LrODC-WT possesses high PLP, while F186A and H346A demonstrated 50% PLP of LrODC-WT, and absent in H216F and E281Q. The crystal structure of LrODC-WT was identified as a tetramer in which PLP was bound to all four subunits and interacted with residue K347 for Schiff base formation. While the crystal structures of H216F and H346A form dimers, an LrODC-WT tetramer can form via hydrogen bonding of D544 and N270. An improved understanding of the structure and function of LrODCs is relevant for controlling its polyamine production and for optimizing <i>L. rhamnosus</i> strains for use as a more potent probiotic.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"730-742"},"PeriodicalIF":1.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.70035","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cover Picture: α-Azaaryl Carbonyl Derivatives in Stereodivergent Catalytic Reactions (BKCS 6/2025) Ilwoo Song, Byungjun Kim, Hooseung Lee, Sarah Yunmi Lee","authors":"","doi":"10.1002/bkcs.12866","DOIUrl":"https://doi.org/10.1002/bkcs.12866","url":null,"abstract":"<p>The cover image depicts a Goldberg machine symbolizing the stereodivergent reaction of α-azaaryl carbonyl derivatives with electrophilic partners (E⁺), producing azaarenes with multiple stereocenters (R,S). By combining a chiral copper Lewis acid with a second chiral catalyst (Ir, Pd, Ni, Ru, or amines) and tuning the stereochemical environment, all possible stereoisomers can be selectively accessed. Details are in the article by Ilwoo Song, Byungjun Kim, Hooseung Lee, and Sarah Yunmi Lee.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 6","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.12866","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144472953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Research progress of cobalt selenide anode materials for metal-ion battery","authors":"Jiaxin Guo, Hongsheng Jiang, Shengkai Li, Jinliang Lin, Donghui Liu, Qi Wang, Bin Feng","doi":"10.1002/bkcs.70043","DOIUrl":"https://doi.org/10.1002/bkcs.70043","url":null,"abstract":"<p>As the demand for large-scale energy storage systems increases, so do market expectations for battery performance, especially in electrochemical properties. Against this background, electrode materials with excellent theoretical capacity and unique structures, such as cobalt selenide (CoSe<sub>2</sub>), have received significant attention from the research community for their potential in large-scale energy storage systems. These materials exhibit excellent electrochemical properties, including long cycle life, high stability, high energy density, and efficient charge/discharge performance. However, CoSe<sub>2</sub> anode materials still face volume expansion and conductivity degradation in practical applications, affecting battery performance and lifetime. To address these challenges, researchers have proposed a variety of innovative strategies. This paper provides an in-depth evaluation of these strategies and analyzes their potential for practical applications. It is shown that by designing special structural materials, shortening the ion migration path, and increasing the contact area, the electrochemical performance can be effectively enhanced and the performance degradation caused by volume change can be suppressed. With technological advances, it is expected that battery performance will be significantly improved, driving the development of more efficient and environmentally friendly energy solutions.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"704-729"},"PeriodicalIF":1.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yejin Kim, Da Han Hyun, Yoon Hee Lee, Woojeong Lim, Hoyeon Lee, Soyeon Lee, Hyeon-Ki Jang, Joohyun Lim, Dae Gy Hong, Jun Seok Park, Soo Yeun Park, Jongmin Park
{"title":"EpCAM and CD24 specific EVRNA analysis for ovarian cancer diagnosis","authors":"Yejin Kim, Da Han Hyun, Yoon Hee Lee, Woojeong Lim, Hoyeon Lee, Soyeon Lee, Hyeon-Ki Jang, Joohyun Lim, Dae Gy Hong, Jun Seok Park, Soo Yeun Park, Jongmin Park","doi":"10.1002/bkcs.70041","DOIUrl":"https://doi.org/10.1002/bkcs.70041","url":null,"abstract":"<p>Extracellular vesicles (EVs) are recently emerged as biomarkers for cancer diagnosis. RNA in EV specifically has drawn attention for its high stability and accuracy for early cancer diagnosis. However, analysis of EV RNA in plasma for cancer diagnosis often can be limited by a low population of cancer-derived EVs in the plasma samples. Herein, we developed a sensitive EV RNA analysis technique with protein-specific EV enrichment for accurate ovarian cancer diagnosis.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"673-679"},"PeriodicalIF":1.7,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eunseo Park, Jieon Lee, Jinhyuk Kim, Gyeongmin Kim, Hyunah Choo, Taek Kang, Byungsun Jeon, Ansoo Lee
{"title":"Biphenylyl-N-ethylethanamines induce ERK phosphorylation through 5-HT7R-Gs signaling pathway","authors":"Eunseo Park, Jieon Lee, Jinhyuk Kim, Gyeongmin Kim, Hyunah Choo, Taek Kang, Byungsun Jeon, Ansoo Lee","doi":"10.1002/bkcs.70030","DOIUrl":"https://doi.org/10.1002/bkcs.70030","url":null,"abstract":"<p>Biphenylyl-<i>N</i>-ethylethanamines, novel 5-HT<sub>7</sub>R agonists synthesized from 4-chloro-3-iodobenaldehyde, activate the Gs signaling pathway. Among derivatives, compounds <b>4c</b> and <b>4f</b> showed potent 5-HT<sub>7</sub>R agonism, with EC<sub>50</sub> values of 89 and 70 nM, respectively, in cAMP assays. Western blot analysis confirmed dose- and time-dependent ERK phosphorylation, with <b>4c</b> and <b>4f</b> inducing sustained pERK expression (14.5- and 11.4-fold at 60 min) compared to 5-HT (4.0-fold), indicating prolonged signaling. Compound <b>4f</b> exhibited acceptable drug-like properties, including minimal CYP inhibition and moderate microsomal stability. These findings highlight the pharmacological potential of <b>4f</b> as a 5-HT<sub>7</sub>R modulator, warranting further in vivo studies to explore its therapeutic applications.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 6","pages":"636-640"},"PeriodicalIF":1.7,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144473034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tough hydrogel designs for stable aqueous zinc ion batteries","authors":"Saehyun Kim, Youn Soo Kim","doi":"10.1002/bkcs.70040","DOIUrl":"https://doi.org/10.1002/bkcs.70040","url":null,"abstract":"<p>Aqueous zinc ion batteries (AZIBs) have emerged as a promising next-generation energy storage technology to replace lithium-ion batteries. Recently, gel polymer electrolytes (GPEs), as a critical component of AZIBs, have garnered significant attention due to their potential to address challenges associated with conventional aqueous electrolytes, such as dendrite growth, corrosion, electrolyte evaporation, and leakage. However, the mechanical properties of hydrogels often remain suboptimal due to inherent limitations. This review focuses on the mechanical requirements that GPEs must meet for practical implementation in AZIBs. Furthermore, it highlights various gel design strategies to achieve superior mechanical performance, including double-network (DN) gels, topological gels, and other advanced gel network architectures. Promising directions and rational perspectives for future research are also proposed, offering insights into the development of high-performance GPEs for AZIBs.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"691-703"},"PeriodicalIF":1.7,"publicationDate":"2025-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fast and stable cycling of 2,6-diaminoanthraquinone as a redox-active organic cathode for sodium-ion batteries","authors":"Honggyu Seong, Youngseok Chang, Jaewon Choi","doi":"10.1002/bkcs.70038","DOIUrl":"https://doi.org/10.1002/bkcs.70038","url":null,"abstract":"<p>Sodium-ion batteries (SIBs) have attracted considerable attention due to their electrochemical similarity to lithium-ion batteries. One approach to advancing the SIB system involves the use of redox-active compounds as sustainable cathode materials. Organic compounds offer the advantage of tunable electrochemical properties, which can be modulated by altering their molecular structures. In this study, the commercially available 2,6-diaminoanthraquinone (2,6-DAAQ) was investigated as a potential cathode material for SIBs. Its sodium-ion storage capabilities were investigated through a combination of electrochemical measurements and density functional theory (DFT) calculations. In addition, the insertion of two Na<sup>+</sup> ions into the 2,6-DAAQ cathode was analyzed via ex situ ATR FT-IR spectroscopy. The results indicate that the carbonyl groups participate in the redox processes during charge–discharge cycling. The 2,6-DAAQ cathode also exhibited excellent cycling stability and rate capability, which can be attributed to its dominant capacitive behavior. Overall, 2,6-DAAQ demonstrated reversible sodium-ion storage, highlighting its potential as a stable organic cathode for next-generation SIBs.</p>","PeriodicalId":54252,"journal":{"name":"Bulletin of the Korean Chemical Society","volume":"46 7","pages":"666-672"},"PeriodicalIF":1.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bkcs.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}