UltrasonographyPub Date : 2023-10-01Epub Date: 2023-04-19DOI: 10.14366/usg.23006
Weiming He, Yuguang Xu, Chaoyang Gong, Xiaozhen Liu, Yuqiang Wu, Xi Xie, Jiazhen Chen, Yi Yu, Zhiyong Guo, Qiang Sun
{"title":"Contrast-enhanced ultrasonography-based renal blood perfusion in brain-dead donors predicts early graft function.","authors":"Weiming He, Yuguang Xu, Chaoyang Gong, Xiaozhen Liu, Yuqiang Wu, Xi Xie, Jiazhen Chen, Yi Yu, Zhiyong Guo, Qiang Sun","doi":"10.14366/usg.23006","DOIUrl":"10.14366/usg.23006","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to quantify renal microcirculatory perfusion in braindead donors using contrast-enhanced ultrasonography (CEUS), and to establish an accurate, noninvasive, and convenient index for predicting delayed graft function (DGF) post-transplantation.</p><p><strong>Methods: </strong>In total, 90 brain-dead donor kidneys (training group, n=60; validation group, n=30) examined between August 2020 and November 2022 were recruited in this prospective study. CEUS was performed on the kidneys of brain-dead donors 24 hours before organ procurement and time-intensity curves were constructed. The main measures were arrival time, time to peak, and peak intensity of the kidney segmental arteries, cortex, and medulla. Recipients were divided into DGF and non-DGF groups according to early post-transplant graft function. The area under the receiver operating characteristic curve (AUC) was used to assess diagnostic performance.</p><p><strong>Results: </strong>The arrival time of the kidney segmental artery and cortex and the time interval between the time to peak of the segmental artery and cortex were identified as independent factors associated with DGF by multivariate stepwise regression analysis. A new index for the joint prediction model of three variables, the contrast-enhanced ultrasonography/Kidney Donor Profile index (CEUS-KDPI), was developed. CEUS-KDPI showed high accuracy for predicting DGF (training group: AUC, 0.91; sensitivity, 90.5%; specificity, 92.3%; validation group: AUC, 0.84; sensitivity, 75.0%; specificity, 92.3%).</p><p><strong>Conclusion: </strong>CEUS-KDPI accurately predicted DGF after kidney transplantation. CEUS may be a potential noninvasive tool for bedside examinations before organ procurement and may be used to predict early renal function after kidney transplants kidneys from donors after brain death.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":" ","pages":"532-543"},"PeriodicalIF":3.1,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/bd/usg-23006.PMC10555683.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10362037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jared Van Reet, Kate Tunnell, Kara Anderson, Hyun-Chul Kim, Evgenii Kim, Kavin Kowsari, Seung-Schik Yoo
{"title":"Evaluation of advective solute infiltration to porous media by pulsed focused ultrasound-induced acoustic streaming effects","authors":"Jared Van Reet, Kate Tunnell, Kara Anderson, Hyun-Chul Kim, Evgenii Kim, Kavin Kowsari, Seung-Schik Yoo","doi":"10.14366/usg.23037","DOIUrl":"https://doi.org/10.14366/usg.23037","url":null,"abstract":"PURPOSE\u0000Acoustic streaming induced by applying transcranial focused ultrasound (FUS) promotes localized advective solute transport in the brain and has recently garnered research interest for drug delivery and enhancement of brain waste clearance. The acoustic streaming behavior in brain tissue is difficult to model numerically and thus warrants an in vitro examination of the effects of using different sonication parameters, in terms of frequency, intensity, and pulse duration (PD).\u0000\u0000\u0000METHODS\u0000Melamine and polyvinyl alcohol (PVA) foams were used to mimic the porous brain tissue, which contains leptomeningeal fenestrations and perivascular space, while agar hydrogel was used to emulate denser neuropil. FUS was delivered to these media, which were immersed in a phosphate-buffered saline containing toluidine blue O dye, across various frequencies (400, 500, and 600 kHz; applicable to transcranial delivery) in a pulsed mode at two different spatialpeak pulse-average intensities (3 and 4 W/cm2).\u0000\u0000\u0000RESULTS\u0000Image analysis showed that the use of 400 kHz yielded the greatest dye infiltration in melamine foam, while sonication had no impact on infiltration in the agar hydrogel due to the dominance of diffusional transport. Using a fixed spatial-peak temporal-average intensity of 0.4 W/cm2 at 400 kHz, a PD of 75 ms resulted in the greatest infiltration depth in both melamine and PVA foams among the tested range (50-150 ms).\u0000\u0000\u0000CONCLUSION\u0000These findings suggest the existence of a specific frequency and PD that induce greater enhancement of solute/fluid movement, which may contribute to eventual in vivo applications in promoting waste clearance from the brain.","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136194013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dongbin Ahn, Ji Hye Kwak, Gil Joon Lee, Jin Ho Sohn
{"title":"Ultrasound-guided ethanol ablation versus Sistrunk operation as a primary treatment for thyroglossal duct cyst","authors":"Dongbin Ahn, Ji Hye Kwak, Gil Joon Lee, Jin Ho Sohn","doi":"10.14366/usg.23128","DOIUrl":"https://doi.org/10.14366/usg.23128","url":null,"abstract":"","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"64 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134968370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Artificial intelligence in breast ultrasound: application in clinical practice","authors":"Hila Fruchtman Brot, Victoria L. Mango","doi":"10.14366/usg.23116","DOIUrl":"https://doi.org/10.14366/usg.23116","url":null,"abstract":"Ultrasonography (renamed from the Journal of Korean Society of Ultrasound in Medicine in January 2014), the official English-language journal of the Korean Society of Ultrasound in Medicine (KSUM), is an international peer-reviewed academic journal dedicated to practice, research, technology, and education dealing with medical ultrasound, Aims and Scope:Ultrasonography (renamed from the Journal of Korean Society of Ultrasound in Medicine in January 2014), the official English-language journal of the Korean Society of Ultrasound in Medicine (KSUM), is an international peer-reviewed academic journal dedicated to practice, research, technology, and education dealing with medical ultrasound.It is published four times per year: January 1, April 1, July 1, and October 1. Original articles, topical reviews, pictorial essays, and notable case reports are published in Ultrasonography covering state-of-the-art content. Ultrasonography also serves as a medium for cooperation among physicians and specialists from around the world who are focusing on various ultrasound technology and disease problems.","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136282829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joep J J Vullings, Caroline van Schaik, Jurgen J Fütterer, Chris L de Korte, Willemijn M Klein
{"title":"Visualizing the lymphatic vessels and flow with high-resolution ultrasonography and microvascular flow imaging.","authors":"Joep J J Vullings, Caroline van Schaik, Jurgen J Fütterer, Chris L de Korte, Willemijn M Klein","doi":"10.14366/usg.22218","DOIUrl":"https://doi.org/10.14366/usg.22218","url":null,"abstract":"<p><p>Imaging of the lymphatic system has always encountered difficulties, such as high costs, timeconsuming procedures, and low-resolution images. Each method of imaging provides its own challenges. The use of high-resolution ultrasonography (HR-US) and microvascular flow imaging (MVFI) may prove to be the most effective method for visualizing the superficial lymphatic vessels. This study investigated the utilization of HR-US and MVFI in imaging inguinal lymph nodes and vessels, as well as the innovative use of an intranodal saline injection that acted as a contrast agent. This technical note aims to demonstrate that HR-US and MVFI, in combination with an intranodal saline injection, are applicable to the dynamic imaging of superficial inguinal lymph nodes and vessels.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 3","pages":"466-473"},"PeriodicalIF":3.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/42/73/usg-22218.PMC10331061.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10146512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
So Yeong Jeong, Jung Hwan Baek, Sae Rom Chung, Young Jun Choi, Ki-Wook Chung, Tae Yong Kim, Jeong Hyun Lee
{"title":"Radiofrequency ablation of benign thyroid nodules: the value of anterolateral hydrodissection.","authors":"So Yeong Jeong, Jung Hwan Baek, Sae Rom Chung, Young Jun Choi, Ki-Wook Chung, Tae Yong Kim, Jeong Hyun Lee","doi":"10.14366/usg.23017","DOIUrl":"https://doi.org/10.14366/usg.23017","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the technical feasibility, efficacy, and safety of anterolateral hydrodissection (ALHD) in radiofrequency ablation (RFA) for benign thyroid nodules.</p><p><strong>Methods: </strong>Between November 2019 and April 2020, 39 patients underwent 41 sessions of RFA with the ALHD technique to treat benign thyroid nodules. ALHD was performed with cold (0°C-4°C) 5% dextrose solution during RFA to minimize pain and secure sufficient safety margins from critical neck structures. The initial ablation ratio (IAR) was measured to assess the technique's efficiency. Ultrasound examinations, symptoms, and cosmetic scores were evaluated pre-procedure and at 6 and 12 months post-procedure. Procedure-related pain during RFA and complications were recorded.</p><p><strong>Results: </strong>The mean index nodule volume was 20.5±21.6 mL. ALHD was technically feasible in all patients. The mean IAR was 90.7%±8.3%, and significant reductions in mean nodule volume were noted at 6- and 12-month follow-ups (P<0.001, 63.9%±19.0%, and 76.3%±18.9%, respectively). Symptom and cosmetic scores showed significant improvements at 6- and 12-month follow-ups (P<0.001). Pain during the procedure was well-controlled with ALHD in all patients. After the initial use of 5-10 mL of lidocaine at the start of the procedure, no further lidocaine injection was given to any patient. Transient voice change was observed in one patient, but the patient recovered spontaneously within 30 minutes.</p><p><strong>Conclusion: </strong>The ALHD technique was technically feasible and effective in all patients, achieving a mean IAR of 90.7%. The ALHD technique also had a pain-relieving effect, resulting in only low amounts of lidocaine administration being required during the procedure.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 3","pages":"432-439"},"PeriodicalIF":3.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c0/63/usg-23017.PMC10331056.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9825986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christoph Schwabl, Gernot Schmidle, Peter Kaiser, Elena Drakonaki, Mihra S Taljanovic, Andrea S Klauser
{"title":"Nerve entrapment syndromes: detection by ultrasound.","authors":"Christoph Schwabl, Gernot Schmidle, Peter Kaiser, Elena Drakonaki, Mihra S Taljanovic, Andrea S Klauser","doi":"10.14366/usg.22186","DOIUrl":"https://doi.org/10.14366/usg.22186","url":null,"abstract":"<p><p>Nerve entrapment syndromes are commonly encountered in clinical practice. Accurate diagnosis and management require a knowledge of peripheral neuroanatomy and the recognition of key clinical symptoms and findings. Nerve entrapment syndromes are frequently associated with structural abnormalities of the affected nerve. Therefore, imaging allows the evaluation of the cause, severity, and etiology of the entrapment. High-resolution ultrasonography can depict early and chronic morphological changes within the entire nerve course and is therefore an ideal modality for diagnosing various nerve entrapment syndromes in different regions. This review article presents some of the most common types of nerve entrapment, with special focus on ultrasound imaging and key findings.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 3","pages":"376-387"},"PeriodicalIF":3.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/33/57/usg-22186.PMC10331057.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10147028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giovanna Ferraioli, Ambra Raimondi, Annalisa De Silvestri, Carlo Filice, Richard G Barr
{"title":"Toward acquisition protocol standardization for estimating liver fat content using ultrasound attenuation coefficient imaging.","authors":"Giovanna Ferraioli, Ambra Raimondi, Annalisa De Silvestri, Carlo Filice, Richard G Barr","doi":"10.14366/usg.23014","DOIUrl":"https://doi.org/10.14366/usg.23014","url":null,"abstract":"<p><strong>Purpose: </strong>This study's primary aim was to assess factors affecting ultrasound attenuation coefficient (AC) measurement repeatability using the Canon ultrasound (US) system. The secondary aim was to evaluate whether similar results were obtained with other vendors' AC algorithms.</p><p><strong>Methods: </strong>This prospective study was performed at two centers from February to November 2022. AC was obtained using two US systems (Aplio i800 of Canon Medical Systems and Arietta 850 of Fujifilm). An algorithm combining AC and the backscatter coefficient was also used (Sequoia US System, Siemens Healthineers). To evaluate inter-observer concordance, AC was obtained by two expert operators using different transducer positions with regions of interest (ROIs) varying in terms of depth and size. Intra-observer concordance was evaluated on measurements performed intercostally, subcostally, and in the left liver lobe. Lin's concordance correlation coefficient was used.</p><p><strong>Results: </strong>Thirty-four participants (mean age, 49.4±15.1 years; 18 females) were studied. AC values progressively decreased with depth. The measurements in intercostal spaces on bestquality US images using a 3-cm ROI with its upper edge 2 cm below the liver capsule during breath-hold showed the highest intra-observer and inter-observer concordance (0.92 [95% confidence interval, 0.88 to 0.95] and 0.89 [0.82 to 0.96], respectively). Measurements in the left lobe showed the lowest intra-observer and inter-observer concordance (0.67 [0.43 to 0.90] and 0.58 [0.12 to 1.00], respectively). Intercostal space measurements also had the highest repeatability for the other two ultrasound systems.</p><p><strong>Conclusion: </strong>AC values obtained in intercostal spaces on best-quality images using a 3-cm ROI placed with its top 2 cm below the liver capsule were highly repeatable.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 3","pages":"446-456"},"PeriodicalIF":3.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d0/33/usg-23014.PMC10331055.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9770873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeanett Klubien, Jacob Rosenberg, Bjørn Ole Skjoldbye, Torben Lorentzen, Christian Pállson Nolsøe, Hans-Christian Lykkegaard Pommergaard
{"title":"Ablation therapy for patients with colorectal liver metastases with and without extrahepatic metastases: evaluation of long-term outcomes and prognostic factors.","authors":"Jeanett Klubien, Jacob Rosenberg, Bjørn Ole Skjoldbye, Torben Lorentzen, Christian Pállson Nolsøe, Hans-Christian Lykkegaard Pommergaard","doi":"10.14366/usg.22208","DOIUrl":"https://doi.org/10.14366/usg.22208","url":null,"abstract":"<p><strong>Purpose: </strong>Ablation is a valuable treatment alternative to surgery for colorectal liver metastases. This study reports the long-term clinical outcomes in patients treated with ablation for colorectal liver metastases with or without extrahepatic metastases.</p><p><strong>Methods: </strong>Patients with colorectal liver metastases treated with ultrasound-guided ablation at Herlev Hospital, Denmark were included in this retrospective study.</p><p><strong>Results: </strong>This study included 284 patients with 582 metastases. Complete ablation was obtained in 258 patients (91%) evaluated within 6 weeks. During follow-up, 94 patients (33%) developed local recurrence. The median survival for all patients was 31 months, with 1-, 3-, and 5-year survival rates of 82%, 45%, and 21%, respectively. The median survival for patients with extrahepatic metastases (n=49, 17%) was 24 months compared with 33 months for patients without (P=0.142). Propensity score-adjusted Cox regression showed that extrahepatic metastases were associated with increased mortality, with a hazard ratio (HR) of 1.45 (95% confidence interval [CI], 1.02 to 2.05; P=0.039). In multivariate Cox regression analysis for all patients, increased mortality risk was found for a diameter ≥2.6 cm (HR, 1.59; 95% CI, 1.23 to 2.05), >1 metastasis (HR, 1.66; 95% CI, 1.28 to 2.16), and extrahepatic metastases (HR, 1.45; 95% CI, 1.04 to 2.03). Male sex (HR, 0.75; 95% CI, 0.58 to 0.98) and receiving chemotherapy (HR, 0.69; 95% CI, 0.52 to 0.92) were associated with decreased mortality.</p><p><strong>Conclusion: </strong>Ablation for colorectal liver metastases offers acceptable survival rates, including for patients with extrahepatic metastases. In addition, chemotherapy was associated with improved survival for both patients with and without extrahepatic metastases.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 3","pages":"410-420"},"PeriodicalIF":3.1,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/dc/usg-22208.PMC10331062.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9760375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}