Soo-Yeon Kim, Han-Byoel Lee, Wonshik Han, Su Hyun Lee, Jung Min Chang, Nariya Cho
{"title":"Role of Doppler US and elastography prior to biopsy to identify candidates for avoidance of surgery following neoadjuvant chemotherapy for breast cancer.","authors":"Soo-Yeon Kim, Han-Byoel Lee, Wonshik Han, Su Hyun Lee, Jung Min Chang, Nariya Cho","doi":"10.14366/usg.22185","DOIUrl":"https://doi.org/10.14366/usg.22185","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the role of Doppler ultrasound (US) and elastography to identify residual breast cancer for patients showing near complete response following chemotherapy on magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>Between September 2016 and January 2018, 40 breast cancer patients who showed near complete response (either tumor size ≤0.5 cm or lesion-to-background parenchymal signal enhancement ratio ≤1.6) on MRI following neoadjuvant chemotherapy were prospectively enrolled. After excluding seven women who did not undergo Doppler US and elastography, 33 women (median age, 49 years; range, 32 to 67 years) were analyzed. On the day of surgery, women underwent Doppler US and elastography for tumor bed prior to US-guided core needle biopsy. Histopathologic results of biopsy and surgery were evaluated. Negative predictive value (NPV) and false negative rate (FNR) of biopsy and the combined Doppler US and elastography were analyzed, respectively.</p><p><strong>Results: </strong>After surgery, nine women had residual cancers and 24 women had pathologic complete response. The NPV and FNR of biopsy were 92% (24 of 26) and 22% (2 of 9), respectively. The NPV and FNR of combined Doppler US and elastography were 100% (14 of 14) and 0% (0 of 9), respectively. All of nine women with residual cancers had positive vascularity or elasticity. Two women with false-negative biopsy results, having 0.3 cm or 2.5 cm ductal carcinoma in situ at surgery, showed positive vascularity or elasticity.</p><p><strong>Conclusion: </strong>Tumor bed showing positive vascularity or elasticity indicates residual breast cancer for patients showing near complete response on MRI following chemotherapy.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"323-332"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d5/00/usg-22185.PMC10071055.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9637995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
UltrasonographyPub Date : 2023-04-01Epub Date: 2022-11-29DOI: 10.14366/usg.22171
Hyunjae Song, Tai-Kyong Song, Jeeun Kang
{"title":"High-contrast spectroscopic photoacoustic characterization of thermal tissue ablation in the visible spectrum.","authors":"Hyunjae Song, Tai-Kyong Song, Jeeun Kang","doi":"10.14366/usg.22171","DOIUrl":"10.14366/usg.22171","url":null,"abstract":"<p><strong>Purpose: </strong>High-contrast tissue characterization of thermal ablation has been desired to evaluate therapeutic outcomes accurately. This paper presents a photoacoustic (PA) characterization of thermal tissue ablation in the visible spectrum, in which higher light absorbance can produce spectral contrast starker than in the near-infrared range.</p><p><strong>Methods: </strong>Ex vivo experiments were performed to measure visible PA spectra (480-700 nm) from fresh porcine liver tissues that received a thermal dose in a range of cumulative equivalent minutes at 43°C (CEM43). The local hemoglobin lobe area between 510-600 nm and wholespectral area under the curve were evaluated to represent the transition of hemoglobin into methemoglobin (MetHb) in the target tissue.</p><p><strong>Results: </strong>The thermal process below an estimated therapeutic CEM43 threshold (80-340 minutes) presented a progressive elevation of the PA spectrum and an eventual loss of local hemoglobin peaks in the visible spectrum, closer to the MetHb spectrum. Interestingly, an excessive CEM43 produced a substantial drop in the PA spectrum. In the spectral analysis, the visible spectrum yielded 13.9-34.1 times higher PA sensitivity and 1.42 times higher contrast change than at a near-infrared wavelength.</p><p><strong>Conclusion: </strong>This novel method of PA tissue characterization in the visible spectrum could be a potential modality to evaluate various thermal therapeutic modalities at high-contrast resolution.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"249-258"},"PeriodicalIF":2.4,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/59/92/usg-22171.PMC10071053.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pelvic hematomas in the postpartum state.","authors":"Smita Manchanda","doi":"10.14366/usg.22201","DOIUrl":"https://doi.org/10.14366/usg.22201","url":null,"abstract":"How to cite this article: Manchanda S. Re: Pelvic hematomas in the postpartum state. Ultrasonography. 2023 Apr; 42(2):354-355. I read with great interest the article published by Vardar et al., entitled \"Pelvic ultrasonography of the postpartum uterus in patients presenting to the emergency room with vaginal bleeding and pelvic pain\" [1]. The authors summarized the imaging manifestations of common causes of vaginal bleeding and pelvic pain in the postpartum state. Hematomas in the postpartum state can occur as a complication of both vaginal and cesarean deliveries. With the rising incidence of cesarean-section deliveries, there has been an increase in the number of post-cesarean complications [2], including subcutaneous hematoma, rectus sheath hematoma, subfascial hematoma, and bladder flap and retroperitoneal hematomas, as described by the authors [1]. However, it is also necessary to keep in mind puerperal hematomas after vaginal delivery. These have been classified as revealed (infralevator) hematomas and concealed hematomas [3]. Infralevator hematomas can be vulval, paravaginal, or ischiorectal in location and are usually diagnosed clinically. Concealed hematomas include supralevator hematomas, broad ligament hematomas, and intraperitoneal or retroperitoneal hematomas and usually present with abdominal pain or varying degrees of shock. A high index of suspicion is required, and the radiologist is often the first person to alert the clinician about this potentially life-threatening diagnosis. Ultrasonography is the baseline imaging modality and allows early detection of pelvic hematomas. Cross-sectional imaging in the form of contrast-enhanced computed tomography is essential to delineate the extent of involvement and may show contrast extravasation from branches of the internal pudendal artery, uterine artery, or the internal iliac artery. Small hematomas can be managed conservatively; however, incision and drainage may be required in larger hematomas. Supralevator perivaginal space hematomas are drained through the vaginal wall and infralevator hematomas through the perineum [4]. Hence, it is essential to distinguish between these two lesion types on computed tomography. Larger hematomas may require exploratory laparotomy. Radiologically guided drainage and transarterial embolization have also been described in the literature as the primary management approaches. In conclusion, the authors have nicely illustrated the ultrasonographic evaluation of varying etiologies of pelvic pain and bleeding in the postpartum state. I would like to add that pelvic hematomas after vaginal delivery, despite their relative infrequency, should also be kept in mind while evaluating such patients in an emergency setting.","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"354-355"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/22/02/usg-22201.PMC10071057.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9252010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae Hyun Kim, Jeong Hee Yoon, Ijin Joo, Jeong Min Lee
{"title":"Intra-individual comparison of two-dimensional shear wave elastography techniques using plane wave imaging and the multi-beam technique: are they interchangeable in measuring liver fibrosis?","authors":"Jae Hyun Kim, Jeong Hee Yoon, Ijin Joo, Jeong Min Lee","doi":"10.14366/usg.22135","DOIUrl":"https://doi.org/10.14366/usg.22135","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared two different two-dimensional shear wave elastography techniques-plane wave imaging (PWI) and multi-beam (MB) imaging-from the same vendor to evaluate liver fibrosis.</p><p><strong>Methods: </strong>In this prospective study, 42 patients with chronic liver disease who had recently undergone magnetic resonance elastography (<3 months) were enrolled, and their liver stiffness (LS) values were measured using PWI or MB. The LS values (kPa) were compared using the Wilcoxon rank-sum test. Inter-technique reproducibility and intra-observer repeatability were assessed using Bland-Altman analysis with 95% limits of agreement (LOA) and coefficients of variation (CVs). The cutoff values for predicting severe fibrosis (≥F3) were estimated using receiver operating characteristic curve (ROC) analysis, with magnetic resonance elastography as the reference standard.</p><p><strong>Results: </strong>PWI exhibited technical failure in four patients. Therefore, 38 patients underwent both examinations. The LS values showed moderate agreement between PWI and MB (CV, 22.5%) and 95% LOA of -3.71 to 7.44 kPa. The MB technique showed good intra-observer agreement (CV, 8.1%), while PWI showed moderate agreement (CV, 11.0%). The cutoff values of PWI and MB for diagnosing ≥F3 were 12.3 kPa and 13.8 kPa, respectively, with areas under the ROC curve of 0.89 and 0.95 (sensitivity, 100% and 100%; specificity, 65.6% and 85.7%).</p><p><strong>Conclusion: </strong>The LS values significantly differed between PWI and MB, hindering their interchangeable use in longitudinal follow-up. Considering its low technical failure rate and better repeatability, the MB technique may be preferable for evaluating liver fibrosis in chronic liver disease patients.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"265-274"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/24/c5/usg-22135.PMC10071060.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9637996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haejung Kim, Jung Hee Shin, Ka Eun Kim, Myoung Kyoung Kim, Jiyun Oh, Soo Yeon Hahn
{"title":"Subcategorization of intermediate suspicion thyroid nodules based on suspicious ultrasonographic findings.","authors":"Haejung Kim, Jung Hee Shin, Ka Eun Kim, Myoung Kyoung Kim, Jiyun Oh, Soo Yeon Hahn","doi":"10.14366/usg.22096","DOIUrl":"https://doi.org/10.14366/usg.22096","url":null,"abstract":"<p><strong>Purpose: </strong>This study compared the malignancy risk of intermediate suspicion thyroid nodules according to the presence of suspicious ultrasonographic (US) findings.</p><p><strong>Methods: </strong>From January 2014 to December 2014, 299 consecutive intermediate suspicion thyroid nodules in 281 patients (mean age, 50.6±12.5 years) with final diagnoses were included in this study. Two radiologists retrospectively reviewed the US findings and subcategorized the intermediate suspicion category into nodules without suspicious findings and nodules with suspicious findings, including punctate echogenic foci, nonparallel orientation, or irregular margins. The malignancy rates were compared between the two subcategory groups.</p><p><strong>Results: </strong>Of the 299 intermediate suspicion thyroid nodules, 230 (76.9%) were subcategorized as nodules without suspicious findings and 69 (23.1%) as nodules with suspicious findings. The total malignancy rate was 33.4% (100/299) and the malignancy rate of nodules with suspicious findings was significantly higher than that of nodules without suspicious findings (47.8% vs. 29.1%, P=0.004). In nodules with suspicious findings, the most common suspicious finding was punctate echogenic foci (48/82, 58.5%) followed by nonparallel orientation (22/82, 26.8%) and irregular margins (12/82, 14.6%). Thirteen nodules had two suspicious findings simultaneously. A linearly increasing trend in the malignancy rate was observed according to the number of suspicious US findings (P for trend=0.001).</p><p><strong>Conclusion: </strong>Intermediate suspicion thyroid nodules with suspicious findings showed a higher malignancy rate than those without suspicious findings. Further management guidelines for nodules with suspicious findings should differ from guidelines for nodules without suspicious findings, even in the same US category.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"307-313"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7f/e3/usg-22096.PMC10071054.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9637994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyuhwan Jung, Sook-Young Woo, A Ran Kim, Honsoul Kim
{"title":"Upper gastrointestinal tract perforation assessed by contrast-enhanced ultrasonography after oral Sonazoid administration in a stomach leakage mouse model.","authors":"Kyuhwan Jung, Sook-Young Woo, A Ran Kim, Honsoul Kim","doi":"10.14366/usg.22192","DOIUrl":"https://doi.org/10.14366/usg.22192","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to elucidate whether contrast-enhanced ultrasonography (CEUS) can visualize orally administered Sonazoid leaking into the peritoneal cavity in a postoperative stomach leakage mouse model.</p><p><strong>Methods: </strong>Adult female mice (n=33, 9-10 weeks old) were used. Preoperative CEUS was performed after delivering Sonazoid via intraperitoneal injection and the per oral route. A gastric leakage model was then generated by making a surgical incision of about 0.5 cm at the stomach wall, and CEUS with per oral Sonazoid administration was performed. A region of interest was drawn on the CEUS images and the signal intensity was quantitatively measured. Statistical analysis was performed using a mixed model to compare the signal intensity sampled from the pre-contrast images with those of the post-contrast images obtained at different time points.</p><p><strong>Results: </strong>CEUS after Sonazoid intraperitoneal injection in normal mice and after oral administration in mice with gastric perforation visualized the contrast medium spreading within the liver interlobar fissures continuous to the peritoneal cavity. A quantitative analysis showed that in the mice with gastric perforation, the orally delivered Sonazoid leaking into the peritoneal cavity induced a statistically significant (P<0.05) increase in signal intensity in all CEUS images obtained 10 seconds or longer after contrast delivery. However, enhancement was not observed before gastric perforation surgery (P=0.167).</p><p><strong>Conclusion: </strong>CEUS with oral Sonazoid administration efficiently visualized the contrast medium spreading within the peritoneal cavity in a postoperative stomach leakage mouse model.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"297-306"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/2f/usg-22192.PMC10071069.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sang Oh Yun, Kyo Won Lee, Jae Berm Park, Min Jung Kim, Sung Yoon Park, Boram Park
{"title":"Impact of preoperative ultrasonography for predicting the prognosis of deceased donor kidney transplantation.","authors":"Sang Oh Yun, Kyo Won Lee, Jae Berm Park, Min Jung Kim, Sung Yoon Park, Boram Park","doi":"10.14366/usg.22132","DOIUrl":"https://doi.org/10.14366/usg.22132","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the role of donor kidney ultrasonography (US) for predicting functional kidney volume and identifying ideal kidney grafts in deceased donor kidney transplantation.</p><p><strong>Methods: </strong>In total, 272 patients who underwent deceased donor kidney transplantation from 2000 to 2020 at Samsung Medical Center were enrolled. Donor kidney information (i.e., right or left) was provided to the radiologist who performed US image re-analysis. To binarize each kidney's ultrasound parameters, an optimal cutoff value for estimated glomerular filtration rate (eGFR) of less than 30 mL/min/1.73 m2 within 1 year after kidney transplantation was selected using the receiver operating characteristic curve with a specificity >60%. Cox regression analysis was performed for an eGFR less than 30 mL/min/1.73 m2 within 1 year after kidney transplantation and graft failure within 2 years after kidney transplantation.</p><p><strong>Results: </strong>The product of renal length and cortical thickness was a statistically significant predictor of graft function. The odds ratios of an eGFR less than 30 mL/min/1.73 m2 within a year after kidney transplantation and the hazard ratio of graft failure within 2 years after kidney transplantation were 5.91 (P=0.003) and 5.76 (P=0.022), respectively.</p><p><strong>Conclusion: </strong>Preoperative US of the donor kidney can be used to evaluate donor kidney function and can predict short-term graft survival. An imaging modality such as US should be included in the donor selection criteria as an additional recommendation. However, the purpose of this study was not to narrow the expanded criteria but to avoid catastrophic consequences by identifying ideal donor kidneys using preoperative US.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"238-248"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/be/usg-22132.PMC10071059.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9623893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Combined fine-needle aspiration with core needle biopsy for assessing thyroid nodules: a more valuable diagnostic method?","authors":"Zhe Chen, Jia-Jia Wang, Dong-Ming Guo, Yu-Xia Zhai, Zhuo-Zhi Dai, Hong-Hui Su","doi":"10.14366/usg.22112","DOIUrl":"https://doi.org/10.14366/usg.22112","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the diagnostic value of combined fine-needle aspiration (FNA) with core needle biopsy (CNB) in thyroid nodules.</p><p><strong>Methods: </strong>FNA and CNB were performed simultaneously on 703 nodules. We compared the proportions of inconclusive results and the diagnostic performance for malignancy among FNA, CNB, and combined FNA/CNB for different nodule sizes.</p><p><strong>Results: </strong>Combined FNA/CNB showed lower proportions of inconclusive results than CNB for all nodules (2.8% vs. 5.7%, P<0.001), nodules ≤1.0 cm (4.9% vs. 7.3%, P=0.063), nodules >1.0 cm (2.0% vs. 5.0 %, P<0.001), nodules ≤1.5 cm (3.8% vs. 7.9 %, P<0.001), and nodules >1.5 cm (2.1% vs. 3.9 %, P=0.016). The sensitivity of combined FNA/CNB in predicting malignancy was significantly higher than that of CNB (89.0% vs. 80.0%, P<0.001) and FNA (89.0% vs. 58.1%, P<0.001) for all nodules. Within American College of Radiology Thyroid and Imaging Reporting and Data System grades 4-5, in the subgroup of nodules ≤1.5 cm, combined FNA/ CNB showed the best sensitivity in predicting malignancy (91.4%), significantly higher than that of CNB (81.0%, P<0.001) and FNA (57.8%, P<0.001). However, in the subgroup of nodules >1.5 cm, the difference between combined FNA/CNB and CNB was not significant (84.2% vs. 78.9%, P=0.500).</p><p><strong>Conclusion: </strong>Regardless of nodule size, combined FNA/CNB tended to yield lower proportions of inconclusive results than CNB or FNA alone and exhibited higher performance in diagnosing malignancy. The combined FNA/CNB technique may be a more valuable diagnostic method for nodules ≤1.5 cm and nodules with a risk of malignancy than CNB and FNA alone.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"314-322"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/b7/usg-22112.PMC10071058.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9257212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyobin Seo, Kwang Nam Jin, Ji Sang Park, Koung Mi Kang, Eun Kyung Lee, Ji Ye Lee, Roh-Eul Yoo, Young Joo Park, Ji-Hoon Kim
{"title":"Risk of thyroid cancer in a lung cancer screening population of the National Lung Screening Trial according to the presence of incidental thyroid nodules detected on low-dose chest CT.","authors":"Hyobin Seo, Kwang Nam Jin, Ji Sang Park, Koung Mi Kang, Eun Kyung Lee, Ji Ye Lee, Roh-Eul Yoo, Young Joo Park, Ji-Hoon Kim","doi":"10.14366/usg.22111","DOIUrl":"https://doi.org/10.14366/usg.22111","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated thyroid cancer risk in a lung cancer screening population according to the presence of an incidental thyroid nodule (ITN) detected on low-dose chest computed tomography (LDCT).</p><p><strong>Methods: </strong>Of 47,837 subjects who underwent LDCT, a lung cancer screening population according to the National Lung Screening Trial results was retrospectively enrolled. The prevalence of ITN on LDCT was calculated, and the ultrasonography (US)/fine-needle aspiration (FNA)-based risk of thyroid cancer according to the presence of ITN on LDCT was compared using the Fisher exact or Student t-test as appropriate.</p><p><strong>Results: </strong>Of the 2,329 subjects (female:male=44:2,285; mean age, 60.9±4.9 years), the prevalence of ITN on LDCT was 4.8% (111/2,329). The incidence of thyroid cancer was 0.8% (18/2,329, papillary thyroid microcarcinomas [PTMCs]) and was higher in the ITN-positive group than in the ITN-negative group (3.6% [4/111] vs. 0.6% [14/2,218], P=0.009). Among the 2,011 subjects who underwent both LDCT and thyroid US, all risks were higher (P<0.001) in the ITNpositive group than in the ITN-negative group: presence of thyroid nodule on US, 94.1% (95/101) vs. 48.6% (928/1,910); recommendation of FNA according to the American Thyroid Association guideline and Korean Thyroid Imaging Reporting and Data System guideline, 41.2% (42/101) vs. 2.4% (46/1,910) and 39.6% (40/101) vs. 1.9% (37/1,910), respectively.</p><p><strong>Conclusion: </strong>Despite a higher risk of thyroid cancer in the LDCT ITN-positive group than in the ITN-negative group in a lung cancer screening population, all cancers were PTMCs. A heavy smoking history may not necessitate thorough screening US for thyroid incidentalomas.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"275-285"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/64/usg-22111.PMC10071062.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9257213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seung-Hyun Lim, Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Hyunmin Kim, Da In Lee, Sung Kyung Moon, Seung Jin Park
{"title":"Ultrasonography of intrascrotal torsed appendages: size and interval between symptom onset and the ultrasonographic examination according to echogenicity.","authors":"Seung-Hyun Lim, Dal Mo Yang, Hyun Cheol Kim, Sang Won Kim, Hyunmin Kim, Da In Lee, Sung Kyung Moon, Seung Jin Park","doi":"10.14366/usg.22169","DOIUrl":"https://doi.org/10.14366/usg.22169","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the size of torsed appendages and the interval between symptom onset and the ultrasonographic examination according to the echogenicity of the torsed appendages.</p><p><strong>Methods: </strong>This was a retrospective analysis of 54 cases in 46 patients with torsion of the testicular appendages between December 2008 and July 2021. Eight patients received follow-up ultrasonography 7-48 days after initial ultrasonography. The echogenicity of torsed appendages was classified into three groups: hypoechoic, hyperechoic, or isoechoic.</p><p><strong>Results: </strong>The 54 torsed appendages were hypoechoic (n=40), hyperechoic (n=9), or isoechoic (n=5). The size of the torsed appendages ranged from 4 to 14 mm (8.0±3.1 mm) in hypoechoic torsed appendages and from 2.6 to 5.0 mm (3.7±0.9 mm) in hyperechoic torsed appendages. The interval between symptom onset and the ultrasonographic examination ranged from 0 to 17 days (4.2±4.4 days) in hypoechoic torsed appendages and from 8 to 48 days (29.8±16.0 days) in hyperechoic torsed appendages. The hyperechoic torsed appendages were smaller and had longer intervals between symptom onset and the ultrasonographic examination than the hypoechoic torsed appendages (P<0.05). Three hypoechoic torsed appendages and a single isoechoic torsed appendage on initial ultrasonography became hyperechoic on follow-up ultrasonography.</p><p><strong>Conclusion: </strong>The size of the torsed appendages and the interval between symptom onset and the ultrasonographic examination varied according to the echogenicity of the torsed appendages. The hyperechoic torsed appendages were smaller and had longer intervals until the examination than the hypoechoic torsed appendages.</p>","PeriodicalId":54227,"journal":{"name":"Ultrasonography","volume":"42 2","pages":"259-264"},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/36/b4/usg-22169.PMC10071070.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9637997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}