Translational Medicine at UniSa最新文献

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Laparoscopic Repair of Paediatric Indirect Inguinal Hernia: Modified Flip Flap Technique. 腹腔镜下小儿腹股沟斜疝修补术:改良翻转瓣技术。
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-31 eCollection Date: 2020-05-01
A Garzi, M Prestipino, E Calabrò, R M Di Crescenzo, M S Rubino
{"title":"Laparoscopic Repair of Paediatric Indirect Inguinal Hernia: Modified Flip Flap Technique.","authors":"A Garzi, M Prestipino, E Calabrò, R M Di Crescenzo, M S Rubino","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In paediatric age, indirect inguinal hernia represents more than 95% of the hernial disease. It is a congenital type, in contrast with adulthood in which acquired forms are more frequently found (1). The laparoscopic correction of indirect inguinal hernia is one of the most common surgeries performed in paediatric age. In recent years, various techniques have been introduced for the videolaparoscopic correction of this disease. The aim of this study is to provide an assessment of the efficacy and safety of the execution of a modified Flip-Flap technique, using tissue glue for filling of Peritoneal-vaginal duct (DPV), performed in order to ensure greater suture tightness and reduce the incidence of postoperative hydrocele. author1, author2, author 2, author1, author1, author 2 The Authors present a retrospective review of their record of cases, considering a total of 187 patients aged between 18 months and 14 years. For the correction of the hernial defect, the modified VLS Flip-Flap technique was carried out. The evaluation of safety, efficacy, operating time, relapse rate and development of short-term complications (such as postoperative hydrocele, scrotal hematoma or ecchymosis, atrophy or iatrogenic testicle ascension) was considered in a mean follow-up of 6 months. The Authors suggest that this variant of the peritoneal Flip-Flap technique is simple to perform; its safety, reproducibility and effectiveness is proven and has a percentage of relapses and complications overlapping with the \"open\" approach and superior to other laparoscopic techniques.</p>","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"22 ","pages":"33-37"},"PeriodicalIF":1.5,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38036754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimally Invasive Treatment of Urolithiasis in Children: Evaluation of the Use of Flexible Ureterorenoscopy and Laser Lithotripsy 儿童尿石症的微创治疗:软性输尿管镜和激光碎石术的应用评价
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-01 DOI: 10.14273/UNISA-2816
A. Garzi, M. Prestipino, E. Calabró, R. D. Di Crescenzo, M. Rubino
{"title":"Minimally Invasive Treatment of Urolithiasis in Children: Evaluation of the Use of Flexible Ureterorenoscopy and Laser Lithotripsy","authors":"A. Garzi, M. Prestipino, E. Calabró, R. D. Di Crescenzo, M. Rubino","doi":"10.14273/UNISA-2816","DOIUrl":"https://doi.org/10.14273/UNISA-2816","url":null,"abstract":"Urolithiasis is a multifactorial disease; in recent years, its incidence has gradually increased in pediatric age. Among the factors involved in urolithiasis pathophysiology, urinary tract anomalies and metabolic diseases are the most relevant, although ethnicity and environmental factors may have an important role. The advances in technology and miniaturization of endoscopic devices have permitted the use of Retrograde Intrarenal Surgery (RIRS) to treat kidney and ureteral stones. Nowadays, flexible ureterorenoscopy and laser lithotripsy, which are techniques that have been applied in the management of adult upper urinary tract disorders, are also used in children as a minimally invasive treatment of urolithiasis with encouraging, effective and safe results. The Authors report a retrospective review of their record of cases considering 21 pediatric urolithiasis treatment procedures performed between October 2017 and April 2019 in a total of 17 patients (10 males and 7 females). Six procedures involved the use of the flexible ureterorenoscope (FURS) while in 15 procedures the application of the laser fiber was used (FURSL). A case of laser lithotripsy for bladder stone was included. The average age of patients was 10.5 years (2–18 years). The renal pelvis dilatation pretreatment was evaluated in post-operative follow-up. From the evaluation of the sample in analysis, the use of RIRS has good results in the treatment of paediatric urolithiasis, emerging as a valid option in the management of the paediatric population in terms of efficacy and safety, with an improvement in patient outcomes.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"22 1","pages":"46 - 49"},"PeriodicalIF":1.5,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46113568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Pleomorphic Adenoma of the Parotid Gland and Ipsilateral Thyroid Incidentaloma: Report of A Rare Case With Review of Literature 腮腺多形性腺瘤及同侧甲状腺偶发瘤1例报告并文献复习
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-01 DOI: 10.14273/UNISA-2822
F. Candelori, A. Minni, A. Greco, A. Scarpa, C. Cassandro, M. Cavaliere, M. Bisognox, E. Cassandro, M. de Vincentiis, M. Ralli
{"title":"Pleomorphic Adenoma of the Parotid Gland and Ipsilateral Thyroid Incidentaloma: Report of A Rare Case With Review of Literature","authors":"F. Candelori, A. Minni, A. Greco, A. Scarpa, C. Cassandro, M. Cavaliere, M. Bisognox, E. Cassandro, M. de Vincentiis, M. Ralli","doi":"10.14273/UNISA-2822","DOIUrl":"https://doi.org/10.14273/UNISA-2822","url":null,"abstract":"Background Pleomorphic adenomas are benign tumors of the salivary glands that mainly affect the lower pole of the superficial lobe of the parotid gland. The term “pleomorphic” refers to the epithelial and connective origin of the mass. The clinical presentation is typically that of asymptomatic swelling which increases in volume. Therapy consists in surgical removal of the tumor mass by parotidectomy with nerve preservation. Case details This clinical case describes an interesting case of pleomorphic adenoma of the parotid gland in a 62-year-old patient. The patient presented with a long history of an asymptomatic mildly worsening swelling of the left parotid region. The peculiarity of the clinical case is the dimension of the adenoma (9x5x9 cm) and the presence of a thyroid incidentaloma (TI), consisting of a thyroid multinodular goiter composed of nodules, the largest of which measured 8 cm in diameter. This mass dislocated the laryngotracheal axis, compressed the larynx and caused the reduction of the respiratory space, making orotracheal intubation difficult and determining the need to perform a tracheotomy. Conclusion Benign pleomorphic adenomas can potentially reach large sizes if untreated. Socio-economic problems may be the reason for late diagnosis.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"22 1","pages":"15 - 18"},"PeriodicalIF":1.5,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47351202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Surgical VLS Therapy of Oesophageal Achalasia in Pediatric Age 小儿食管失弛缓症的VLS手术治疗
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-01 DOI: 10.14273/UNISA-2817
A. Garzi, M. Prestipino, M. Rubino, E. Calabró
{"title":"Surgical VLS Therapy of Oesophageal Achalasia in Pediatric Age","authors":"A. Garzi, M. Prestipino, M. Rubino, E. Calabró","doi":"10.14273/UNISA-2817","DOIUrl":"https://doi.org/10.14273/UNISA-2817","url":null,"abstract":"The Authors present a retrospective review of their record of cases, characterized by 4 cases of achalasia in which it was performed a Heller myotomy with front fundoplication (Thall) in laparoscopic approach in the period from 2012 to 2019. In paediatric achalasia, the laparoscopic Heller myotomy seems to be the best treatment because of its multiple advantages offered by the minimally invasive technique. First of all, thanks to the video-technique, which allows a complete and extended myotomy, the accuracy of this operation is maximized; moreover, the post-operative pain is widely reduced, thanks to the minimal dissection and traction of the tissues; finally, but not negligible, this approach ensures a better aesthetic result than the classic open technique. With regard to the front fundoplication, the Authors suggest that it is mandatory because, even if it extends the operating time, it ensures a natural protection to the myotomy herniated mucosa and avoids gastro-oesophageal reflux, which often occurs after the surgical correction, thus obliging to perform a reoperation.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":" 17","pages":"38 - 43"},"PeriodicalIF":1.5,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41254493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mozart’s or Ambient Music do not Affect Autoalgometric Pain Threshold 莫扎特或环境音乐不会影响自动算法疼痛阈值
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-01 DOI: 10.14273/UNISA-2825
N. Vecchione, L. Lorusso, A. Viggiano
{"title":"Mozart’s or Ambient Music do not Affect Autoalgometric Pain Threshold","authors":"N. Vecchione, L. Lorusso, A. Viggiano","doi":"10.14273/UNISA-2825","DOIUrl":"https://doi.org/10.14273/UNISA-2825","url":null,"abstract":"Nowadays, researchers and clinicians are increasingly interested in alternative non-pharmacological treatments, and music therapy seems to have additional and powerful effects on different pathologies and pain. However, since pain is a subjective perception, it is difficult to evaluate if and which effect music has on it. In this study, a new device and method have been introduced to objectively estimate pain threshold and its changes related to external stimuli. The above-mentioned device, called autoalgometer, allows to evaluate pain threshold changes while listening to music or other sounds. In this experiment, the pain threshold was evaluated in twenty-seven volunteers after listening to one out of three different soundtracks: white noise, Mozart’s sonata K448 or Brian Eno’s ambient music. Compared to staying in silence, listening to the recordings had no significant effect on pain threshold, and the results did not show any significant difference between the experimental groups. Probably, the positive effect of music described in other studies can be ascribed to a psychological effect, meaning that music can improve subjective mood and, thus, modify pain perception.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"22 1","pages":"1 - 4"},"PeriodicalIF":1.5,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42546029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effects of Polyurethane Foam Dressings as an Add-on Therapy in the Management of Digital Ulcers in Scleroderma Patients 聚氨酯泡沫敷料在硬皮病患者指溃疡治疗中的作用
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-01 DOI: 10.14273/UNISA-2823
F. Rossi, F. Rivellese, F. Napolitano, F. Mosella, C. Selleri, N. Montuori, A. de Paulis
{"title":"Effects of Polyurethane Foam Dressings as an Add-on Therapy in the Management of Digital Ulcers in Scleroderma Patients","authors":"F. Rossi, F. Rivellese, F. Napolitano, F. Mosella, C. Selleri, N. Montuori, A. de Paulis","doi":"10.14273/UNISA-2823","DOIUrl":"https://doi.org/10.14273/UNISA-2823","url":null,"abstract":"Digital ulcers (DUs) represent a severe and common complication occurring in patients affected by Systemic Sclerosis (SSc), with a consistent impact on the quality of life and often resulting in longer hospitalization than unaffected patients. Conventional treatment of SSc ulcers consists of both topical and systemic (oral or intravenous) pharmacological therapies. Several surgical options are also available, but there is overall a lack of official guidelines or recommendations. The aim of this study was to evaluate the efficacy of a novel local therapy based on polyurethane foam dressings, namely the Highly Hydrophilic Polyurethane Foam (HPF), in addition to the conventional pharmacological treatment, in a cohort of 41 SSc patients with at least one active ulcer. Our results showed that the addition of HPF to the conventional treatment based on systemic drugs induced i) a significant reduction in the number of active DUs (p=0.0034); ii) a significant reduction of the mean duration of ulcer-related hospitalization as compared with standard therapy (p=0.0001); iii) a significant improvement of patients’ Quality of Life, as evaluated through the Scleroderma Health Assessment Questionnaire (SHAQ) (p=0.00011). Therefore, in our experience, the combined management of DUs can improve both the onset of new DUs and DU’s healing thus leading to a better outcome.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"22 1","pages":"10 - 14"},"PeriodicalIF":1.5,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47008266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Dietary Restriction for The Treatment of Meniere’s Disease 梅尼埃病的饮食限制治疗
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-05-01 DOI: 10.14273/UNISA-2824
P. Luca, C. Cassandro, M. Ralli, F. Gioacchini, R. Turchetta, M. P. Orlando, I. Iaccarino, M. Cavaliere, E. Cassandro, A. Scarpa
{"title":"Dietary Restriction for The Treatment of Meniere’s Disease","authors":"P. Luca, C. Cassandro, M. Ralli, F. Gioacchini, R. Turchetta, M. P. Orlando, I. Iaccarino, M. Cavaliere, E. Cassandro, A. Scarpa","doi":"10.14273/UNISA-2824","DOIUrl":"https://doi.org/10.14273/UNISA-2824","url":null,"abstract":"Meniere’s disease (MD) is an idiopathic inner ear disorder characterized by spontaneous recurrent vertigo, fluctuating sensorineural hearing loss (SNHL), aural fullness and tinnitus. Endolymphatic hydrops (EH) of the inner ear is currently considered the pathophysiological mechanisms that underlies typical symptoms of MD. MD diagnosis is based on the criteria of the Baràny Society. There are many therapeutic options for MD, but none is considered effective by the scientific community. The first-line treatment commonly includes dietary modification, as low salt diet and reduction of alcohol and caffeine daily intake. Although some studies showed a positive effect of these dietary restrictions, even in the prevention of recurrences, currently there is no uniform consensus on their usefulness. New dietary approach, such SPC-flakes, are being evaluated: further assessments will be needed to validate their use in clinical practice.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"22 1","pages":"5 - 9"},"PeriodicalIF":1.5,"publicationDate":"2020-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41629188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 12
Evidence on the Need for an Integrated Approach to the Management of Diabetes: The Diagnostic Perspective if Osteomyelitis is Suspected 糖尿病综合治疗的必要性证据:怀疑骨髓炎的诊断视角
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-02-20 DOI: 10.14273/UNISA-2808
B. Saleem
{"title":"Evidence on the Need for an Integrated Approach to the Management of Diabetes: The Diagnostic Perspective if Osteomyelitis is Suspected","authors":"B. Saleem","doi":"10.14273/UNISA-2808","DOIUrl":"https://doi.org/10.14273/UNISA-2808","url":null,"abstract":"19 Università degli Studi di Salerno Background According to the International Diabetes Federation 9.3% of adults aged 20–79 years (463 million people worldwide) are living with diabetes and the number is still raising: this will lead to an increased number of expected complications, including infections. Besides, at least half of all amputations occur in people with diabetes, most commonly because of an infected diabetic foot ulcer. Diabetic foot osteomyelitis (DFO) remain the most frequent diabetic complication, associated with substantial morbidities, requiring hospitalization, daily wound care, antimicrobial therapy and is the most common precipitating event leading to lower extremity amputation. DFO is associated with high health care costs.","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"21 1","pages":"19 - 20"},"PeriodicalIF":1.5,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42904526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A New Strategy for a High Tumour Burden Region: The Campania Oncological Network. 高肿瘤负担地区的新策略:坎帕尼亚肿瘤网络。
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-02-20 eCollection Date: 2020-01-01
S De Placido, U Bracale, R Pacelli, M Sodo, G Merola, V Silvestri, F Corcione
{"title":"A New Strategy for a High Tumour Burden Region: The Campania Oncological Network.","authors":"S De Placido,&nbsp;U Bracale,&nbsp;R Pacelli,&nbsp;M Sodo,&nbsp;G Merola,&nbsp;V Silvestri,&nbsp;F Corcione","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"21 ","pages":"59-60"},"PeriodicalIF":1.5,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37698720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence on the need for an integrated approach to the management of diabetes: the surgical perspective. 需要一种综合方法来管理糖尿病的证据:外科视角。
IF 1.5
Translational Medicine at UniSa Pub Date : 2020-02-20 eCollection Date: 2020-01-01
C Setacci, G de Donato, M Tadiello, M Tozzi, G Bracale, L Del Guercio, U M Bracale, F Setacci
{"title":"Evidence on the need for an integrated approach to the management of diabetes: the surgical perspective.","authors":"C Setacci,&nbsp;G de Donato,&nbsp;M Tadiello,&nbsp;M Tozzi,&nbsp;G Bracale,&nbsp;L Del Guercio,&nbsp;U M Bracale,&nbsp;F Setacci","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":54170,"journal":{"name":"Translational Medicine at UniSa","volume":"21 ","pages":"4-6"},"PeriodicalIF":1.5,"publicationDate":"2020-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7039262/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37698812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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