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Orbital apex syndrome as an unusual complication of herpes zoster ophthalmicus in HIV-positive young man: a case report 眼窝尖综合征是一种罕见的并发症带状疱疹眼炎在艾滋病毒阳性的年轻人:1例报告
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.99684
Saidatulakma Shariff, Nur Najwa Suhaifi, Tan Chai Keong, Akmal Haliza Binti Zamli, K. Teo
{"title":"Orbital apex syndrome as an unusual complication of herpes zoster ophthalmicus in HIV-positive young man: a case report","authors":"Saidatulakma Shariff, Nur Najwa Suhaifi, Tan Chai Keong, Akmal Haliza Binti Zamli, K. Teo","doi":"10.5114/hivar.2020.99684","DOIUrl":"https://doi.org/10.5114/hivar.2020.99684","url":null,"abstract":"Herpes zoster ophthalmicus (HZO) is a neurocutaneous disease caused by reactivation of herpes zoster infection from latent phase after varicella infection in elderly population. It affects ophthalmic division of trigeminal nerve. Common ocular presentation includes conjunctivitis, anterior uveitis, and keratitis. Orbital apex syndrome rarely occurs as a complication of herpes zoster ophthalmicus in young human immunodeficiency virus (HIV)-positive men. A 20-year-old, recently diagnosed HIV-positive man, presented with vesicular skin rashes over right periorbital and forehead area, associated with right eye redness. He was treated as herpetic zoster ophthalmicus with oral antiviral (acyclovir). Three days later, he developed right eye ptosis, reduced visual acuity, anisocoria, and total ophthalmoplegia. An orbit magnetic resonance imaging showed swelling of all rectus muscles of right eye with right optic nerve perineural enhancement. Diagnosis of right eye herpes zoster ophthalmicus with orbital apex syndrome was established, and intravenous acyclovir was initiated. Systemic antiviral acyclovir continued for up to 10 days. Upon discharge, his ocular features improved; however, his visual impairment persisted. Orbital apex syndrome is a rare complication of herpes zoster ophthalmicus. This irreversible sightthreatening complication can be prevented by early diagnosis of HZO and immediate starting of antiviral treatment. HIV AIDS Rev 2020; 19, 3: 212-216 DOI: https://doi.org/10.5114/hivar.2020.99684","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72504439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The comparison of cognitive function disorder before and after early therapy for cerebral toxoplasmosis in HIV/AIDS patients HIV/AIDS脑弓形虫病早期治疗前后认知功能障碍的比较
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.93159
B. Munir, S. Rianawati, Harun Al Rosyid
{"title":"The comparison of cognitive function disorder before and after early therapy for cerebral toxoplasmosis in HIV/AIDS patients","authors":"B. Munir, S. Rianawati, Harun Al Rosyid","doi":"10.5114/hivar.2020.93159","DOIUrl":"https://doi.org/10.5114/hivar.2020.93159","url":null,"abstract":"Introduction: Toxoplasmosis is a common opportunistic disease that also affects human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients, but there are currently no research studies about cognitive function in cerebral toxoplasmosis patients, especially in terms of the effect of early treatment for this disease. The aim of the study was to compare cognitive function disorder of cerebral toxoplasmosis patients before and after early treatment of cerebral toxoplasmosis. Material and methods: The longitudinal study were conducted among neuroinfection patients who registered in the Neurology Department of Saiful Anwar Hospital, Malang, Indonesia during JanuaryDecember 2016. The inclusion criteria were: cerebral toxoplasmosis patients, HIV-positive status, head computed tomography (CT) scan performed, IgG and IgM toxoplasmosis, and patients willing participate in the study. The exclusion criteria were: other masses in the brain besides toxoplasmaderived, depression, patients not cooperative, or loss of consciousness. Samples were taken by continuous random sampling with Mini-Mental State Examination and Clock Drawing Test. The duration for anti-toxoplasma early therapy was 2-4 weeks. Results: From a total of 31 patients, 13 patients met the inclusion criteria, with an average age of 37 years old (range, 26-67 years). The average CD4+ was 45.75 dl (8-85 dl). The result of cognitive function examination for pre-therapy was 24.85 and after therapy 26.54 (p = 0.07). The clock-drawing test before treatment was 3.15 and increased to 3.39 after treatment (p = 0.41). Conclusion: No significant difference in cognitive function disorder before and after cerebral toxoplasmosis early therapy was found. HIV AIDS Rev 2020; 19, 1: 30-33 DOI: https://doi.org/10.5114/hivar.2020.93159","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/hivar.2020.93159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71090710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stigma and gender dimension based on rural and urban communities in preventing HIV and AIDS in childbearing age couples in Banyumas Regency 巴尤马斯县农村和城市社区在预防育龄夫妇艾滋病毒和艾滋病方面的耻辱和性别层面
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.93178
Colti Sistiarani, Bambang Hariyadi, Munasib Munasib, S. M. Sari
{"title":"Stigma and gender dimension based on rural and urban communities in preventing HIV and AIDS in childbearing age couples in Banyumas Regency","authors":"Colti Sistiarani, Bambang Hariyadi, Munasib Munasib, S. M. Sari","doi":"10.5114/hivar.2020.93178","DOIUrl":"https://doi.org/10.5114/hivar.2020.93178","url":null,"abstract":"Introduction: Transmission of human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) becomes a serious problem in Banyumas Regency, particularly in Cilongok and South Purwokerto sub-districts. The aim of this study was to map the stigma and analyze the gender dimensions according to access, roles, benefit, and control. Material and methods: This was a cross-sectional study, with a quantitative approach. The population and sample taken in a quantitative research included 193 participants of fertile age couples (couples of childbearing age) in Banyumas Regency from Cilongok and South Purwokerto sub-district. Paired t-test was used for data analysis. Results: Based on the research, most of the respondents were between 36 and 49 years old (66.33%). Men and women ratio were almost equal, resulting in 49.74% and 50.26%, respectively. The majority of respondents had a high level of education (39.37%), not working resulted in 53.88%, while those having children accounted for 67.87%. The outcomes of the study revealed that there was no stigma reduction in role and gender equality improvement according to sex category. There were differences in role reduction stigma between urban and rural communities, and also differences in the role of gender equality improvement in urban and rural areas. Conclusions: There are differences in role reduction stigma and also discrepancies in the role of gender equality improvement between urban and rural communities. It is important to pay attention to residence area factor in the effort of implementing a prevention program for HIV and AIDS. It can be related to the prevailing approaches to HIV and AIDS prevention policies and programs. HIV AIDS Rev 2020; 19, 1: 61-66 DOI: https://doi.org/10.5114/hivar.2020.93178","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/hivar.2020.93178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71090950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Periodontitis as a reservoir of human papillomavirus in the causation of oral squamous cell carcinoma: a review 牙周炎作为人乳头瘤病毒的储存库在口腔鳞状细胞癌的病因:综述
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.96430
Akanksha Raj, N. Shetty
{"title":"Periodontitis as a reservoir of human papillomavirus in the causation of oral squamous cell carcinoma: a review","authors":"Akanksha Raj, N. Shetty","doi":"10.5114/hivar.2020.96430","DOIUrl":"https://doi.org/10.5114/hivar.2020.96430","url":null,"abstract":"Human papillomavirus (HPV) is a DNA virus from Papillomavirus family, and is one of the most widely reported sexual infection, which is not only related to ano-genital malignancies, but also associated with head and neck cancers, with chronic periodontitis being one of the risk factor for the same. Chronic periodontitis leads to loss of tissue structures of and around periodontium and is clinically detectable in the form of periodontal pocket and loss of alveolar bone. A variety of other systemic diseases have also been found to be linked to chronic periodontitis, such as cardiovascular diseases, respiratory diseases, etc., and recent data show that it is also related to malignancies of oral cavity. Junctional epithelium of periodontal pocket helps HPV to survive by facilitating the cellular functions to grow and hence, acts as a reservoir for the virus. Porphyromonas gingivalis, a Gram-negative anaero bic bacteria and HPV interacts both directly and indirectly in a series of complex reactions and as a result of some inflammatory reactions, this association further leads to commencement and progression of head and neck squamous cell carcinoma or oral squamous cell carcinoma. This article reviews the pathophysiology of oral human papillomavirus infection and its role in head and neck cancers, with chronic periodontitis as one of the causative factors. HIV AIDS Rev 2020; 19, 2: 74-77 DOI: https://doi.org/10.5114/hivar.2020.96430","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/hivar.2020.96430","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71091037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trend of HIV and tuberculosis co-epidemics in different regions of World Health Organization during 2003-2017 2003-2017年世界卫生组织不同区域艾滋病毒和结核病共流行趋势
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.99688
A. Mehri, Y. Alimohamadi, M. Mohammadi, M. Sepandi, F. Khodamoradi, Firooz Eesmaeilzadeh
{"title":"Trend of HIV and tuberculosis co-epidemics in different regions of World Health Organization during 2003-2017","authors":"A. Mehri, Y. Alimohamadi, M. Mohammadi, M. Sepandi, F. Khodamoradi, Firooz Eesmaeilzadeh","doi":"10.5114/hivar.2020.99688","DOIUrl":"https://doi.org/10.5114/hivar.2020.99688","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71091323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Evaluation of healthcare usage rate in HIV/AIDS patients in Isfahan, Iran in 2018 2018年伊朗伊斯法罕市艾滋病毒/艾滋病患者医疗保健使用率评估
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.93179
Neda Moein, R. Khadivi, Z. Amini, M. Meshkati
{"title":"Evaluation of healthcare usage rate in HIV/AIDS patients in Isfahan, Iran in 2018","authors":"Neda Moein, R. Khadivi, Z. Amini, M. Meshkati","doi":"10.5114/hivar.2020.93179","DOIUrl":"https://doi.org/10.5114/hivar.2020.93179","url":null,"abstract":"Introduction: Universal health coverage (UHC) was introduced in Iran in 2014. The aim of this study was to evaluate the usage rate of health services by human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) patients after UHC implementation. Material and methods: In 2018, in a cross-sectional study, we evaluated the outpatients’ needs (within its previous month) and inpatients’ needs (within its previous 6 months) of HIV/AIDS patients in Isfahan province (the center of Iran). Concurrently, we estimated the essential health care services that HIV/AIDS patients have to receive regularly, including vaccination for hepatitis B, measurement of CD4, tuberculosis (TB) assessments and TB treatment, anti-retroviral therapy, examination of viral load, treatment approach, and drug side effects counseling. Two checklists were used for assessing the utilization of health services and essential health cares for HIV/AIDS patients, validated by the Ministry of Health and Medical Education of Iran. Data were analyzed by χ 2 test, Pearson’s correlation coefficient, and Spearman’s correlation test. Results: Two hundred and thirteen HIV/AIDS patients completed the questionnaires. The mean age of participants was 41.14 ± 9.23. The outpatient service utilization rate was 31.94% in the previous month and the rate of hospitalization was 126 per 1,000 HIV/AIDS patients in the previous 6 months. The majority of HIV/AIDS patients received essential health services more often than the national standard goals estimation. Conclusions: After UHC implementation, the utilization rate of outpatients and inpatients services in HIV/AIDS patients was more than similar indices in the general population. In addition, HIV/AIDS patients received essential health services adequately.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74439104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Blood pressure in relation to the World Health Organization AIDS clinical staging among adults living in rural Kenya 肯尼亚农村成年人的血压与世界卫生组织艾滋病临床分期的关系
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.96242
M. Kamiński, P. Prymas, Anna Konobrodzka, P. Filberek, G. Sibrecht, Wojciech Sierocki, Z. Osińska, P. Bogdański
{"title":"Blood pressure in relation to the World Health Organization AIDS clinical staging among adults living in rural Kenya","authors":"M. Kamiński, P. Prymas, Anna Konobrodzka, P. Filberek, G. Sibrecht, Wojciech Sierocki, Z. Osińska, P. Bogdański","doi":"10.5114/hivar.2020.96242","DOIUrl":"https://doi.org/10.5114/hivar.2020.96242","url":null,"abstract":"Introduction: Human immunodeficiency virus (HIV) is an independent risk factor of arterial hypertension. There is a limited data on blood pressure among HIV-positive patients living in rural areas in Africa according to the clinical progress of the disease. The aim of the study was to compare blood pressure (BP) parameters among HIV-positive adults with advanced and non-advanced HIV/acquired immunodeficiency syndrome (AIDS) living in rural Kenya. Material and methods: In this prospective, two-center, cross-sectional study, we examined HIV-positive individuals visiting the outpatient department for a routine check-up. BP was measured by OMRON M2 Basic BP monitor (Omron, Japan) and clinical data was collected from patients’ data charts. World Health Organization AIDS clinical stage (WACS) equal to 1 was defined as non-advanced HIV, while WACS equals 2, 3, or 4 were classified as advanced HIV. Data presented as median (inter-quartile range). Results: From the total of 245 (female, 192; 78%) participants, 162 individuals presented non-advanced HIV disease, whereas 83 had advanced HIV. Both groups did not differ significantly regarding sex, age, time since HIV diagnosis, body mass index, waist circumference, use of antiretroviral treatment, nor presence of abnormal blood pressure. However, there were significant differences between patients with non-advanced HIV and advanced HIV in diastolic BP (DBP) [71 (64-77) vs. 81 (75-88); p < 0.0001], mean BP (MBP) [87 (80-94) vs. 95 (88-102); p < 0.0001], and pulse pressure (PP) [48 (42-56) vs. 43 (35-50); p < 0.0001]. A tendency, but not significant difference between study groups in systolic BP [119 (109-129) vs. 122 (114-133); p = 0.07] was observed. Conclusions: HIV-positive patients with advanced form of HIV disease have higher DBP, MBP, and lower PP than individuals with non-advanced HIV living in rural Kenya.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84028441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A retrospective study on adverse obstetric outcomes in HIV-infected pregnancy in West Bengal, India 印度西孟加拉邦艾滋病毒感染妊娠的不良产科结局回顾性研究
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.93189
S. Ganguly, Debjit Chakraborty, D. N. Goswami
{"title":"A retrospective study on adverse obstetric outcomes in HIV-infected pregnancy in West Bengal, India","authors":"S. Ganguly, Debjit Chakraborty, D. N. Goswami","doi":"10.5114/hivar.2020.93189","DOIUrl":"https://doi.org/10.5114/hivar.2020.93189","url":null,"abstract":"Introduction: Human immunodeficiency virus (HIV) does not change the course of pregnancy, but seems to exert adverse obstetric outcomes like low birth weight, spontaneous abortion, or stillbirth. Antiretroviral treatment seems to reduce the chance of adverse outcomes. Frequently, HIV-infected women also seems to opt for medical termination of pregnancy (MTP). This study is to compare adverse obstetric outcomes and MTP rate for HIV-infected pregnancy with that in the general population irrespective of antiretroviral treatment (ART). Material and methods: A retrospective cohort study was carried out through analysis of secondary data from 314 integrated counselling and testing centers across the state of West Bengal from October 2016 to December 2017. A total number of 227 HIV-infected on ART pregnancies, whose obstetric outcomes happened during the study period were followed up, and rate for low birth weight, spontaneous abortion, stillbirth, and MTP were calculated, and it was compared with still birth rate of the state among all pregnancies as per data of the District Level Household Survey 4 from 2013. Results: Rates for low birth weight (28.04 per 100 pregnancy outcomes), spontaneous abortion (4.85 per 100), stillbirth (2.64 per 100), and MTP (9.25 per 100 live birth) were found to be significantly high for HIV-infected pregnancies on ART, as compared to the general population. MTP rates and low birth weight rates for general pregnancies did not fall within the 95% confidence interval of those rates for HIV-infected pregnancies. Conclusion: HIV infection was responsible for significant adverse obstetric outcome irrespective of antiretroviral treatment. HIV AIDS Rev 2020; 19, 1: 39-42 DOI: https://doi.org/10.5114/hivar.2020.93189","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/hivar.2020.93189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71090666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge regarding post-exposure prophylaxis amongst nurses in an African context 非洲护士接触后预防知识
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.93331
L. Makhado, Boipelo Seekane
{"title":"Knowledge regarding post-exposure prophylaxis amongst nurses \u0000in an African context","authors":"L. Makhado, Boipelo Seekane","doi":"10.5114/hivar.2020.93331","DOIUrl":"https://doi.org/10.5114/hivar.2020.93331","url":null,"abstract":"Occupational exposure to human immunodeficiency virus (HIV) among nurses had been reported to be a major challenge in South African and broader African context. There seems to be an increase in the level of exposure and uptake of post-exposure prophylaxis (PEP) in Africa. This had warranted the need to establish a systematic review on the level of knowledge among nurses regarding PEP in the African continent. The search engines used included: EBSco Host (North-West University [NWU] library), Sabinet, Google Scholar, ScienceDirect, and PubMed. The search was limited to the current decade (2008-2018), including articles that are in English.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.5114/hivar.2020.93331","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71091020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
HIV care cascade in Albania: analysis of newly diagnosed cases in 2016 阿尔巴尼亚艾滋病毒护理级联:2016年新诊断病例分析
IF 0.2
HIV & AIDS Review Pub Date : 2020-01-01 DOI: 10.5114/hivar.2020.101681
A. Harxhi, E. Vrapi, Arsilda Gjataj, E. Meta, A. Simaku, R. Bani, D. Gökengin, Colette Smith, M. Youle
{"title":"HIV care cascade in Albania: analysis of newly diagnosed cases in 2016","authors":"A. Harxhi, E. Vrapi, Arsilda Gjataj, E. Meta, A. Simaku, R. Bani, D. Gökengin, Colette Smith, M. Youle","doi":"10.5114/hivar.2020.101681","DOIUrl":"https://doi.org/10.5114/hivar.2020.101681","url":null,"abstract":"Introduction: Despite the fact that there has been a steady rise in new infections rate since the first reported case in 1993, Albania remains a low prevalence country. This was the first cascade study for Albania. The aim was to construct a cascade of care for newly human immunodeficiency virus (HIV)-diagnosed individuals in 2016 in Albania. Material and methods: This retrospective descriptive study was conducted at the HIV/AIDS Ambulatory Clinic, Infectious Disease Service, University Hospital Centre of Tirana. Medical records of patients diagnosed and enrolled in care in 2016 were retrospectively screened and data on gender, age, HIV clinical stage, CD4+ T cell count, viral load measurement, and treatment history, with antiretroviral treatment (ART) and adherence to treatment were collected. Results: Out of 127 new HIV cases reported, 100 (78.7%) entered care. The median age was 39 years (range, 20-75 years; male, 82%). Seventy one percent started ART within a median of 56 days (range, 1-317 days) from diagnosis, 34 (47.9%) patients received tenofovir disoproxil fumarate/emtricitabine + efavirenz (EFV), and 27 (38%) zidovudine + lamivudine + EFV. Among those who started ART, 19.7% were late presenters and 54.9% were very late presenters. Viral load after initiation of ART was assessed in 25 cases, with 56% of patients achieving an undetectable HIV-RNA. Conclusions: A large proportion of people living with HIV were lost at each step of the cascade. Efforts in Albania should be focused on scaling up HIV testing, promoting adherence to ART, improving access to diagnostics, and better ART regimens as well as proper monitoring of therapy.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78316801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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