HIV & AIDS Review最新文献

Vaccination against COVID-19 and SARS-COV-2 in people living with HIV 为艾滋病毒感染者接种COVID-19和SARS-COV-2疫苗

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112756

Fábio Cardoso, C. G. Lima da Silva, Sávio Samuel Feitosa Machado, Sionara Melo Figueiredo de Carvalho, Modesto Leite Rolim Neto, Jaime Emanuel Brito Araújo

引用次数: 0

Clinical experience with dolutegravir: efficacy, safety, and tolerability 多替重力韦的临床经验:疗效、安全性和耐受性

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112580

I. Furtado, S. Valdoleiros, J. Fragoso, O. Vasconcelos, M. Gonçalves, R. Sarmento-Castro

引用次数: 0

Primary syphilis as oral lesion in HIV/AIDS-positive patient: case report of unusual manifestation HIV/ aids阳性患者口腔原发性梅毒病变:异常表现1例报告

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112682

Isabella Damiani, M. N. Naval Machado, Melissa Rodrigues de Araújo, Antônio Adilson Soares de Lima

引用次数: 0

Self-esteem and self-efficacy among HIV-positive adolescents: an intervention study hiv阳性青少年的自尊与自我效能:一项干预研究

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112718

Rosa Nimmy Mathew, Manjula M.Y.

引用次数: 1

Cases of HIV testing among pregnant women attending antenatal care during COVID-19 pandemic: analysis of data surveillance COVID-19大流行期间接受产前保健的孕妇中艾滋病毒检测病例:数据监测分析

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.113388

Fitriana Kurniasari Solikhah

{"title":"Cases of HIV testing among pregnant women attending antenatal care during COVID-19 pandemic: analysis of data surveillance","authors":"Fitriana Kurniasari Solikhah","doi":"10.5114/hivar.2022.113388","DOIUrl":"https://doi.org/10.5114/hivar.2022.113388","url":null,"abstract":"Introduction: During COVID-19 pandemic, human immunodeficiency virus (HIV) test surveillance of pregnant women visiting antenatal care (ANC) clinics was used to estimate participation of pregnant women in HIV testing. Socio-demographic recording of HIV patients was conducted to gain a better knowledge of the disease profile, and to aid into the development of more effective HIV prevention and care strategies. Demographic studies of pregnant women who test positive for HIV can serve as proxies for targeted HIV interventions in a wider community as well as mother-to-child transmission prevention. Material and methods: A total of 607 pregnant women, aged 15-49 years, who first visited ANC clinic during a period of January-March 2020 were enrolled. Samples were gathered for three months, or until target sample size was met. Chi-square test was performed to determine various age factors. Link between demographic characteristics and risk of HIV infection was determined using logistic regression approach with SPSS version 26.0. Results: Overall, no demographic variables were found to be substantially associated with HIV prevalence. However, research on demographic characteristics, history of HIV testing, and COVID-19 pandemic revealed that the most conducted tests were among young, less educated, primigravida, and rural women with poor socio-economic status. Conclusions: There is a relationship between parity, employment status, education level, and age and HIV testing among pregnant women during the COVID-19 pandemic. © 2022 Termedia Publishing House Ltd.. All rights reserved.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82493059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival analysis and predictors of mortality for adult HIV/AIDS patients following antiretroviral therapy in Mizan-Tepi University Teaching Hospital, Southwest Ethiopia: a retrospective cohort study 埃塞俄比亚西南部Mizan-Tepi大学教学医院接受抗逆转录病毒治疗的成年艾滋病毒/艾滋病患者的生存分析和死亡率预测因素:一项回顾性队列研究

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112758

B. Teshale, S. Awoke

{"title":"Survival analysis and predictors of mortality for adult HIV/AIDS patients following antiretroviral therapy in Mizan-Tepi University Teaching Hospital, Southwest Ethiopia: a retrospective cohort study","authors":"B. Teshale, S. Awoke","doi":"10.5114/hivar.2022.112758","DOIUrl":"https://doi.org/10.5114/hivar.2022.112758","url":null,"abstract":"Introduction: Acquired immune deficiency syndrome (AIDS) is a medical condition caused by human immunodeficiency virus (HIV), and has been the major concern worldwide. Despite antiretroviral treatment (ART) treatment showing significant clinical importance by meeting the goal of therapy, there is still a number of deaths due to socio-economic, demographic, and health-related factors. Therefore, this study was aimed to investigate the survival status and predictors of mortality for adult HIV-positive patients treated with ART. Material and methods: A retrospective cohort study was conducted with 1,285 of HIV-infected patients aged 15 years and greater, who were enrolled in ART at Mizan-Tepi University Teaching Hospital from September, 2007 to January, 2015. A multivariable Cox regression model was applied to assess significant predictors of mortality. Results: During follow-up period, a total of 1,285 patients contributed to 59,237 person/year of followup, and 273 (21%) of the patients died, showing overall incidence rate of 4.6 per 1,000 persons/ year (273/59,237). The median follow-up period was 44 months. During follow-up, 273 (21%) patients died, of whom nearly 32% and 12% of deaths occurred within 6 months and between 6 and 12 months of highly active antiretroviral therapy (HAART) initiation, respectively. Conclusions: Multivariable Cox proportional hazards model revealed that having concomitant tuberculosis infection, low baseline CD4 count, low baseline weight, living in rural area, using of a substance, older age, lower educational level, higher World Health Organization (WHO) clinical stages, functional status, and marital status were all significantly associated with progression to death for HIV/AIDS-infected patients. HIV AIDS Rev 2022; 21, 1: DOI: https://doi.org/10.5114/hivar.2022.112758","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74362040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Reverse transcriptase inhibition: a way to defeat HIV 逆转录酶抑制:一种战胜艾滋病毒的方法

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112762

Vikas Kumar, H. Joshi, I. Pandey

{"title":"Reverse transcriptase inhibition: a way to defeat HIV","authors":"Vikas Kumar, H. Joshi, I. Pandey","doi":"10.5114/hivar.2022.112762","DOIUrl":"https://doi.org/10.5114/hivar.2022.112762","url":null,"abstract":"Human immunodeficiency virus (HIV) induces disease in humans that is known as AIDS (acquired immunodeficiency syndrome). First AIDS cases were registered in 1981, and later, types of HIV infection, such as HIV-1 and HIV-2 were identified. HIV belongs to class of retroviruses, known as ‘lenti-viruses’ and ‘slow’ viruses. A literature assessment was conducted through several reliable national and international journals as well as books and monographs, to investigate reverse transcriptase inhibitor (RI) from human immunodeficiency virus type 1 (HIV-1). Reverse transcriptase inhibitor limits the reverse transcriptase activity, which is considered the key enzyme of retroviral multiplication process, and eventually prevents infection and progression of retroviruses. In the current paper, more than twenty-five drugs were presented, which are used for management/treatment of AIDS. The aim of the present review was to summarize the latest update on reverse transcriptase inhibition. Lately, significant advancement has been observed on the growth of HIV-drugs targeting reverse transcriptase enzyme. There is a continuous increase in various compounds with anti-HIV activity and isolated from natural sources. The present review provided a selection of publications concerning the topic. Salient features of reverse transcriptase inhibitors (both NRTIs and NNRTI's) and possibility for development of new chemical entity were presented.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80150521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Application of machine learning and deep learning for the prediction of HIV/AIDS 机器学习和深度学习在艾滋病预测中的应用

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.112852

Minyechil Alehegn

引用次数: 1

Developing Aysoo: a mobile-based self-management application for people living with HIV 开发Aysoo:一款针对艾滋病毒感染者的移动自我管理应用程序

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HIV & AIDS Review Pub Date : 2022-01-01 DOI: 10.5114/hivar.2022.113389

R. Safdari, Seyedahmad Seyedalinaghi, N. Mohammadzadeh, T. Noori, Pakzad Rahmati, Kowsar Qaderi, F. Voltarelli, E. Mehraeen

引用次数: 3

Intimate partner violence among HIV-positive service users of a tertiary care and treatment facility in Enugu State, Nigeria 尼日利亚埃努古州三级保健和治疗机构中艾滋病毒阳性服务使用者的亲密伴侣暴力

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HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/hivar.2021.111896

Ifeoma M. Obionu, Chinwendu O. Echefu, Vina U. Chinweokwu, Winifred O. Chineme, Azodo U. Gabriel, Emmanuel N. Aguwa

{"title":"Intimate partner violence among HIV-positive service users of a tertiary care and treatment facility in Enugu State, Nigeria","authors":"Ifeoma M. Obionu, Chinwendu O. Echefu, Vina U. Chinweokwu, Winifred O. Chineme, Azodo U. Gabriel, Emmanuel N. Aguwa","doi":"10.5114/hivar.2021.111896","DOIUrl":"https://doi.org/10.5114/hivar.2021.111896","url":null,"abstract":"Introduction: There have been growing concerns of intimate partner violence (IPV) in people living with HIV (PLHIV). The objective of this study was to determine the prevalence and predictors of IPV in PLHIV. Material and methods: This was an analytical cross-sectional study carried out in Enugu State, Southeast Nigeria, among 360 PLHIV receiving care in a tertiary hospital. A systematic sampling method was used to select participants during clinic visits, and data was collected using a pretested questionnaire adapted from Nigerian demographic and health survey. Responses were based on incidents, which had occurred within a period of twelve months prior to the day of interview. P -values of < 0.05 were considered statistically significant. Results: The mean age of respondents was 35 ± 5 years. One hundred and eighty-nine (52.5%) respondents had experienced a form of IPV in the last 12 months preceding the study. Being female and having a partner who uses illicit drugs or alcohol were found to be predictors of IPV (AOR = 2.251, 95% CI: 1.438-3.522) and (AOR = 1.467, 95% CI: 0.301-0.725), respectively. Conclusions: Prevalence of IPV was high in respondents in this study and in light of these findings, there is need to facilitate IPV screening, counseling, and improve patient awareness of IPV in routine management of PLHIV in care and treatment facilities in Nigeria.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85035659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0