HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/hivar.2021.109264
Jacob Musinsky, A. Noy
{"title":"Remission of a primary effusion lymphoma with initiation of highly active antiretroviral therapy and antiviral therapy in a previously untreated HIV-positive patient","authors":"Jacob Musinsky, A. Noy","doi":"10.5114/hivar.2021.109264","DOIUrl":"https://doi.org/10.5114/hivar.2021.109264","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"129 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73354295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/hivar.2021.111896
Ifeoma M. Obionu, Chinwendu O. Echefu, Vina U. Chinweokwu, Winifred O. Chineme, Azodo U. Gabriel, Emmanuel N. Aguwa
{"title":"Intimate partner violence among HIV-positive service users of a tertiary care and treatment facility in Enugu State, Nigeria","authors":"Ifeoma M. Obionu, Chinwendu O. Echefu, Vina U. Chinweokwu, Winifred O. Chineme, Azodo U. Gabriel, Emmanuel N. Aguwa","doi":"10.5114/hivar.2021.111896","DOIUrl":"https://doi.org/10.5114/hivar.2021.111896","url":null,"abstract":"Introduction: There have been growing concerns of intimate partner violence (IPV) in people living with HIV (PLHIV). The objective of this study was to determine the prevalence and predictors of IPV in PLHIV. Material and methods: This was an analytical cross-sectional study carried out in Enugu State, Southeast Nigeria, among 360 PLHIV receiving care in a tertiary hospital. A systematic sampling method was used to select participants during clinic visits, and data was collected using a pretested questionnaire adapted from Nigerian demographic and health survey. Responses were based on incidents, which had occurred within a period of twelve months prior to the day of interview. P -values of < 0.05 were considered statistically significant. Results: The mean age of respondents was 35 ± 5 years. One hundred and eighty-nine (52.5%) respondents had experienced a form of IPV in the last 12 months preceding the study. Being female and having a partner who uses illicit drugs or alcohol were found to be predictors of IPV (AOR = 2.251, 95% CI: 1.438-3.522) and (AOR = 1.467, 95% CI: 0.301-0.725), respectively. Conclusions: Prevalence of IPV was high in respondents in this study and in light of these findings, there is need to facilitate IPV screening, counseling, and improve patient awareness of IPV in routine management of PLHIV in care and treatment facilities in Nigeria.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"17 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85035659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/hivar.2021.111903
Akanksha Raj, Damodar Hegde, Devesh Gupta, Sangeeta U. Nayak
{"title":"Treatment of mucocele of the lower lip using diode laser in a pediatric patient: interdisciplinary case report","authors":"Akanksha Raj, Damodar Hegde, Devesh Gupta, Sangeeta U. Nayak","doi":"10.5114/hivar.2021.111903","DOIUrl":"https://doi.org/10.5114/hivar.2021.111903","url":null,"abstract":"Mucocele or mucus extravasation cyst is a common oral cavity lesion, involving minor salivary glands, and results from duct rupture or obliteration, causing glandular contents (mucinous) to be released subepithelially. The incidence is high, with 2.5 lesions per 1,000 individuals. Indeed, mucoceles are the most common minor salivary gland disorder, and represent the second most frequent benign soft tissue tumors of the oral cavity, following irritative fibromas. Trauma, parafunctional behavior, lip chewing, and other etiological factors may contribute to a permanent bump in the region of incidence if left untreated. These are non-neoplastic cystic lesions of the major and minor salivary glands caused by mucus accumulation. Children are the most often affected by these lesions. Various treatment modalities for mucocele have been advocated, with lasers being the most recent and innovative. In the current case report, a diode laser was used to remove a mucocele on the lower lip, with benefits of less pain, bleeding, recurrence, and greater patient compliance. While these lesions are usually treat-ed with local surgical excision, in our case, to prevent intra-operative surgical complications, such as bleeding and edema, and to facilitate faster healing, excision was performed using a diode laser with a wavelength of 940 nm. After achieving hemostasis, the excised tissue was sent for histopathological examination, which confirmed our diagnosis of that lesion as mucus extravasation cyst or mucocele.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"25 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84088580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107235
Irene Rethemiotaki
{"title":"Vigilance for HIV/AIDS: a cross-sectional study of 2 million adults in the United States","authors":"Irene Rethemiotaki","doi":"10.5114/HIVAR.2021.107235","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107235","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"57 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82773128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107234
Magdalena Jachymek, M. Braksator, M. Parczewski, M. Peregud-Pogorzelska, J. Kaźmierczak
{"title":"Cardiovascular disease and HIV infection","authors":"Magdalena Jachymek, M. Braksator, M. Parczewski, M. Peregud-Pogorzelska, J. Kaźmierczak","doi":"10.5114/HIVAR.2021.107234","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107234","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87809876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/hivar.2021.109648
J. Anejo-Okopi, H. Onywera, S. Omale, O. Audu
{"title":"Non-AIDS defining malignancies among HIV-infected patients","authors":"J. Anejo-Okopi, H. Onywera, S. Omale, O. Audu","doi":"10.5114/hivar.2021.109648","DOIUrl":"https://doi.org/10.5114/hivar.2021.109648","url":null,"abstract":"Malignancies are a major cause of morbidity and mortality in human immunodeficiency virus (HIV)infected patients. With the introduction of an effective combination of antiretroviral therapy, HIV infection has been changed from being a death sentence to a chronic condition. There is renewed clinical interest in the associated morbidities of non-communicable diseases, and most importantly cancers, such as Kaposi’s sarcoma and non-Hodgkin’s lymphoma, due to prolonged survival on antiretrovirals. Available evidence suggests that there is an increasing frequency of cancers associated with bacterial and viral infections among the HIV-infected population. There is also a concern about the etiology of emergence of cancers, risk factors, and viral infections in HIV-infected individuals. The challenge is for the caregivers to develop and implement effective means to screen, treat, and prevent non-AIDS defining cancers (NADCs) in the HIV-infected patients. There is a need for provision of hepatitis B virus and human papillomavirus vaccines for those who are uninfected and the eligible population. Emphasis should be on these non-AIDS defining cancers during health education, in order to create awareness of the morbidity that may encourage screening uptake, thus resulting in healthy living and reduced mortality rates. This brief review aimed to bring to fore the account of NADCs, risk factors, the role of the microbiota, diagnostic methods, and the need for urgent screening and prevention among people living with HIV/AIDS. HIV AIDS Rev 2021; 20, 3: 151-157 DOI: https://doi.org/10.5114/hivar.2021.109648","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"9 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89511187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/hivar.2021.111534
D. Daniella, Alfred Setyono, Marianto Marianto
{"title":"COVID-19 among HIV-infected population","authors":"D. Daniella, Alfred Setyono, Marianto Marianto","doi":"10.5114/hivar.2021.111534","DOIUrl":"https://doi.org/10.5114/hivar.2021.111534","url":null,"abstract":"Novel coronavirus disease 2019, COVID-19, has been declared as a pandemic on March 11th, 2020. The devastating impact of COVID-19 has affected every sectors and individuals worldwide. No definite and specific treatment has been discovered up till now, apart from symptomatic or experimental treatments. Individuals with chronic disease comorbidity are identified to have worse outcomes and greater risk of mortality. Moreover, certain chronic infectious disease, such as human immunodeficiency virus (HIV), is also included as affected individuals by COVID-19 with unknown extent. Various recent studies suggested that there is no higher risk of COVID-19 among HIV-infected population, but subjects are limited. Additionally, controversies still exist regarding the outcome of COVID-19 in HIVinfected population as well as the role of antiretroviral therapy (ART) in COVID-19. Another problems regarding COVID-19 pandemic in this context impede medical access and disturb adherence to ART in HIV patients, further increasing risk of lethal morbidity and mortality of COVID-19. Because of the urgency of COVID-19 pandemic as well as chronicity, mortality, and great number of HIV infections, clinicians should be aware of the relationship between HIV infection and COVID-19. This review article summarized the association between HIV infection and COVID-19 during the pandemic, including the current evidence of ART in COVID-19.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"38 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82711693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.107219
A. Kiwanuka, E. Walakira, L. Andersson, D. Mafigiri
{"title":"Impact of stigma on HIV treatment seeking behavior among the youth living with HIV and AIDS in sub-Saharan Africa: critical review of literature","authors":"A. Kiwanuka, E. Walakira, L. Andersson, D. Mafigiri","doi":"10.5114/HIVAR.2021.107219","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.107219","url":null,"abstract":"","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81131892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/HIVAR.2021.105050
P. Achdiat, Rasmia Rowawi, H. Gunawan, O. Suwarsa, Catherina Jessica Sutantoyo
{"title":"Clinical dermatoscopical response of glycyrrhizinic acid 0.1% spray in treating external anogenital warts in HIV patients: a case series","authors":"P. Achdiat, Rasmia Rowawi, H. Gunawan, O. Suwarsa, Catherina Jessica Sutantoyo","doi":"10.5114/HIVAR.2021.105050","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105050","url":null,"abstract":"Patients with human immunodeficiency virus (HIV) disease are more likely to develop anogenital warts (AGW) compared to HIV-negative people, and are susceptible to treatment failures and illness recurrences. Glycyrrhizinic acid (GA) is extracted from licorice root (Glycyrrhiza glabra). Previous studies have demonstrated the efficacy of GA 0.1% spray as a treatment for external AGW, but its role in immunocompromised patients has not been explored. The current study reported two cases of HIV-positive patients with AGW who experienced partial remission using GA 0.1% spray. The treatment was applied by the patients three times a day for eight weeks. Treatment evaluation were made by using visual inspection and dermoscopy image analysis. After twelve weeks, clinical observation revealed poor improvement with only slight reduction in number and size of the lesions; although dermoscopy findings revealed an evolution from finger-like to knob-like pattern. GA facilitate the development of T helper lymphocytes in cell-mediated immune response, whereas in HIV, there are a decreased number of T helper lymphocytes. This may explain poor therapeutic response in our patient. Dermoscope is useful in the evaluation of treatment progress, especially when invisible to unaided eye. HIV AIDS Rev 2021; 20, 1: 65-69 DOI: https://doi.org/10.5114/hivar.2021.105050","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"20 1","pages":"65-69"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71091520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HIV & AIDS ReviewPub Date : 2021-01-01DOI: 10.5114/hivar.2021.111536
T. Mikuła, Dagny C. Krankowska, A. Wiercińska-Drapało
{"title":"The newest and classic biomarkers of sepsis in HIV-infected adult patients","authors":"T. Mikuła, Dagny C. Krankowska, A. Wiercińska-Drapało","doi":"10.5114/hivar.2021.111536","DOIUrl":"https://doi.org/10.5114/hivar.2021.111536","url":null,"abstract":"Sepsis is one of the major causes of mortality of patients worldwide, and patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) are at higher risk of developing it. Given the importance of quick diagnosis, the demand for sepsis biomarkers is high. In this article, the authors reviewed the available sepsis biomarkers, and assessed whether the biomarkers were analyzed in patients with HIV/AIDS. We investigated the available literature on classic inflammatory biomarkers, such as procalcitonin (PCT) and interleukin-6 (IL-6) as well as new biomarkers of sepsis, including soluble form of urokinase-type plasminogen activator receptor (suPAR), proadrenomedullin (proADM), soluble triggering receptor expressed on myeloid cells 1 (sTREM-1), growth arrest-specific 6 (Gas6), and microRNA (miRNA) in immunocompetent patients and patients living with HIV/AIDS. Various biomarkers have a diagnostic value (PCT, sTREM-1), others present a prognostic value (suPAR, Gas6, PSP, HBP), and some biomarkers have both values (IL-6, proADM, sCD14-ST, miRNA). Combining at least two different biomarkers has the best potential to bring high sensitivity and specificity of diagnosis. To our knowledge, many of discussed novel inflammatory biomarkers, such as presepsin, pancreatic stone protein/regenerating protein (PSP/reg), or heparin-binding protein (HBP), were not yet studied in a population of patients with HIV/AIDS and sepsis. of sepsis. Monitoring at least two biomarkers might increase the chance of early detection of sepsis. Further research is needed to find biomarkers diagnosing sepsis in patients with AIDS.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"242 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80526169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}