HIV & AIDS Review最新文献_第3页

Clinical dermatoscopical response of glycyrrhizinic acid 0.1% spray in treating external anogenital warts in HIV patients: a case series 0.1%甘草酸喷雾治疗HIV患者外生殖器疣的临床皮镜反应:一个病例系列

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.105050

P. Achdiat, Rasmia Rowawi, H. Gunawan, O. Suwarsa, Catherina Jessica Sutantoyo

{"title":"Clinical dermatoscopical response of glycyrrhizinic acid 0.1% spray in treating external anogenital warts in HIV patients: a case series","authors":"P. Achdiat, Rasmia Rowawi, H. Gunawan, O. Suwarsa, Catherina Jessica Sutantoyo","doi":"10.5114/HIVAR.2021.105050","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105050","url":null,"abstract":"Patients with human immunodeficiency virus (HIV) disease are more likely to develop anogenital warts (AGW) compared to HIV-negative people, and are susceptible to treatment failures and illness recurrences. Glycyrrhizinic acid (GA) is extracted from licorice root (Glycyrrhiza glabra). Previous studies have demonstrated the efficacy of GA 0.1% spray as a treatment for external AGW, but its role in immunocompromised patients has not been explored. The current study reported two cases of HIV-positive patients with AGW who experienced partial remission using GA 0.1% spray. The treatment was applied by the patients three times a day for eight weeks. Treatment evaluation were made by using visual inspection and dermoscopy image analysis. After twelve weeks, clinical observation revealed poor improvement with only slight reduction in number and size of the lesions; although dermoscopy findings revealed an evolution from finger-like to knob-like pattern. GA facilitate the development of T helper lymphocytes in cell-mediated immune response, whereas in HIV, there are a decreased number of T helper lymphocytes. This may explain poor therapeutic response in our patient. Dermoscope is useful in the evaluation of treatment progress, especially when invisible to unaided eye. HIV AIDS Rev 2021; 20, 1: 65-69 DOI: https://doi.org/10.5114/hivar.2021.105050","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"20 1","pages":"65-69"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71091520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The newest and classic biomarkers of sepsis in HIV-infected adult patients hiv感染成人患者败血症的最新和经典生物标志物

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/hivar.2021.111536

T. Mikuła, Dagny C. Krankowska, A. Wiercińska-Drapało

{"title":"The newest and classic biomarkers of sepsis in HIV-infected adult patients","authors":"T. Mikuła, Dagny C. Krankowska, A. Wiercińska-Drapało","doi":"10.5114/hivar.2021.111536","DOIUrl":"https://doi.org/10.5114/hivar.2021.111536","url":null,"abstract":"Sepsis is one of the major causes of mortality of patients worldwide, and patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) are at higher risk of developing it. Given the importance of quick diagnosis, the demand for sepsis biomarkers is high. In this article, the authors reviewed the available sepsis biomarkers, and assessed whether the biomarkers were analyzed in patients with HIV/AIDS. We investigated the available literature on classic inflammatory biomarkers, such as procalcitonin (PCT) and interleukin-6 (IL-6) as well as new biomarkers of sepsis, including soluble form of urokinase-type plasminogen activator receptor (suPAR), proadrenomedullin (proADM), soluble triggering receptor expressed on myeloid cells 1 (sTREM-1), growth arrest-specific 6 (Gas6), and microRNA (miRNA) in immunocompetent patients and patients living with HIV/AIDS. Various biomarkers have a diagnostic value (PCT, sTREM-1), others present a prognostic value (suPAR, Gas6, PSP, HBP), and some biomarkers have both values (IL-6, proADM, sCD14-ST, miRNA). Combining at least two different biomarkers has the best potential to bring high sensitivity and specificity of diagnosis. To our knowledge, many of discussed novel inflammatory biomarkers, such as presepsin, pancreatic stone protein/regenerating protein (PSP/reg), or heparin-binding protein (HBP), were not yet studied in a population of patients with HIV/AIDS and sepsis. of sepsis. Monitoring at least two biomarkers might increase the chance of early detection of sepsis. Further research is needed to find biomarkers diagnosing sepsis in patients with AIDS.","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"242 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80526169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological well-being and gender difference in alcohol and substance use among people living with HIV/AIDS 艾滋病毒/艾滋病感染者在酒精和药物使用方面的心理健康和性别差异

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.107238

A. Obadeji, L. Oluwole, B. Kumolalo, A. S. Ajiboye

引用次数: 1

Fertility desire and associated factors among HIV-positive women attending ART clinics in Afar region, Northeast Ethiopia 埃塞俄比亚东北部阿法尔地区接受抗逆转录病毒治疗的艾滋病毒阳性妇女的生育意愿及其相关因素

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/hivar.2021.111395

Etsay Woldu Anbesu, Aydahis Ali Mohammed

{"title":"Fertility desire and associated factors among HIV-positive women attending ART clinics in Afar region, Northeast Ethiopia","authors":"Etsay Woldu Anbesu, Aydahis Ali Mohammed","doi":"10.5114/hivar.2021.111395","DOIUrl":"https://doi.org/10.5114/hivar.2021.111395","url":null,"abstract":"Introduction: Human immune deficiency virus (HIV)-infected individuals experience significant implications in terms of having children due to transmission of human immune deficiency. However, fertility desire has given little attention, and the uptake of prevention of mother-to-child transmission services is low in Ethiopia, particularly in Afar region. Thus, this study aimed to assess fertility desire and associated factors among human immune virus-positive women attending ART clinics. Material and methods: An institution-based cross-sectional study was conducted with 402 HIV-positive women attending anti-retroviral therapy clinics in selected hospitals of Afar region. Logistic regression analysis was employed to identify factors associated with fertility desire. Statistical association was measured, with a p-value < 0.05 considered statistically significant. Results: The prevalence of fertility desire was 63.9% (95% CI: 59.1-68.8%). Young ages women, i.e., 15-24 years (AOR = 11.98; 95% CI: 4.04-35.5) and 25-34 years (AOR = 2.93, 95% CI: 1.46-5.86), who did not have living children (AOR = 5.1; 95% CI: 1.31-20.2) and women with 1 or 2 children alive (AOR = 2.7; 95% CI: 1.39-5.27), and disclosed sero-status (AOR = 5.89; 95% CI: 2.33-14.9) were associated with increased odds of fertility desire. However, contraceptives use was associated with decreased odds of fertility desire (AOR = 0.11; 95% CI: 0.05-0.22). Conclusions: In this study, six in ten study subjects had fertility desires. Young age, not having living child, having 1 or 2 children alive, disclosing sero-status to partner, and contraceptive use were predictors for fertility desire. HIV AIDS Rev 2021; 20, 4: 281-286 DOI: https://doi.org/10.5114/hivar.2021.111395","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"118 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85349790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Partner’s profile and unmet need for child limiting among women living with HIV in Ibadan, Nigeria 尼日利亚伊巴丹市艾滋病毒感染妇女的伴侣概况和未满足的限制儿童需求

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.107239

J. Akinyemi, O. Eniade, R. Afolabi, O. Awolude

引用次数: 0

Development and validation of psychometric properties of a questionnaire for sexual health literacy related to HIV/AIDS and sexually transmitted diseases among Iranian young men 制定和验证伊朗青年男子与艾滋病毒/艾滋病和性传播疾病有关的性健康知识调查表的心理测量特性

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.105106

L. Karimi, F. Rahmati, A. Parandeh

{"title":"Development and validation of psychometric properties of a questionnaire for sexual health literacy related to HIV/AIDS and sexually transmitted diseases among Iranian young men","authors":"L. Karimi, F. Rahmati, A. Parandeh","doi":"10.5114/HIVAR.2021.105106","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105106","url":null,"abstract":"Introduction: Worldwide, sexually transmitted diseases and acquired immunodeficiency syndrome (AIDS) are major health issues. Sexual health literacy refers to a range of sexual health literacy that encompasses a variety of areas, including gender and sexual development, puberty, pregnancy, contraceptive methods, unwanted pregnancy, and sexually transmitted diseases. The evaluation of sexual health literacy needs an appropriate tool. The aim of this study was to develop and evaluate psychometric properties of an instrument to measure sexual health literacy related to AIDS and sexually transmitted diseases among young Iranian men between the ages of 19 to 29 years old. Material and methods: This study was carried in out two phases in Tehran during 2018-2019. In the first phase, a questionnaire was developed by item generation through an expert panel and literature review. In the second part, an assessment of psychometric properties of questionnaire, including face and content validity, was performed. Reliability of questionnaire was assessed using internal consistency (Cronbach’s a) and interclass correlation coefficient (ICC). Results: The content validity indices (CVI and CVR) for all items were 0.89 and 0.87, respectively. The designed tool showed a high internal consistency reliability, with Cronbach’s a ranging from 0.79 to 0.87 and ICC ranging from 0.79 to 0.87. Conclusions: The psychometric assessment of the 30-item questionnaire indicates desirable validity and reliability. This questionnaire is recommended for assessing the level of sexual health literacy of young men in future studies. HIV AIDS Rev 2021; 20, 1: 26-32 DOI: https://doi.org/10.5114/hivar.2021.105106","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91329739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Multi-level intervention for HIV/AIDS caring in Indonesian community 印尼社区艾滋病毒/艾滋病关怀的多层次干预

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.107217

Tantut Susanto, R. Yunanto, Hanny Rasni, Latifa Aini Susumaningrum

引用次数: 0

Depression literacy among people living with HIV/AIDS in a Nigerian tertiary hospital 尼日利亚一家三级医院中艾滋病毒/艾滋病感染者的抑郁素养

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.107218

D. Aluh, Obinna C. Anyachebelu, A. Isah

引用次数: 1

Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges 加纳青少年艾滋病毒感染的矛盾经历:生理挑战

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/HIVAR.2021.105087

A. Doat, E. Navab, A. Hoseini

{"title":"Paradoxical experiences of Ghanaian adolescents with HIV: physiological challenges","authors":"A. Doat, E. Navab, A. Hoseini","doi":"10.5114/HIVAR.2021.105087","DOIUrl":"https://doi.org/10.5114/HIVAR.2021.105087","url":null,"abstract":"Introduction: Adolescents living with human immunodeficiency virus (HIV) in sub-Saharan Africa continue to experience extreme health vulnerabilities. Children with HIV may experience major physiological problems. This study explored the experience of Ghanaian adolescents with HIV. Material and methods: Semi-structured interviews were used to collect data. 12 adolescents living with HIV between the ages of 14 to 19 years were recruited. Since a physiological problem is not without some level of emotional consequence, the most appropriate method to explore these physiological and emotional dimensions of treatment and diseases are through a qualitative research method. Results: Two main themes emerged from this study: ‘Rhapsody of physiological burden’ and ‘Bittersweet experience of adjusting to antiretroviral therapy (ART)’. Participants reported experiencing challenges, including bouts of headaches, itchy skin rashes, general body weakness, vomiting, appetite loss, diarrhea, and many more. Adolescents reported varying accounts concerning ART. Some patients described positive image of treatment, while others reported traumatic ordeal regarding side effects of the treatment to the extent that some stopped taking their medications. Conclusions: Policies aimed at supporting adolescents living with HIV needs to consider their unique set of physiological challenges to help improve health outcomes of the youngsters. Nurses should inform patients about results as well as possible side effects of ART prior initiation of the regimen, and also explain adverse events, which should be reported to hospital. concepts,","PeriodicalId":53943,"journal":{"name":"HIV & AIDS Review","volume":"27 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91334668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Relationship between stigma and health-related quality of life in patients diagnosed with HIV 艾滋病患者的病耻感与健康相关生活质量的关系

IF 0.2

HIV & AIDS Review Pub Date : 2021-01-01 DOI: 10.5114/hivar.2021.108786

Susana Barradas, C. Finck

引用次数: 0