艾滋病毒感染患者中非艾滋病定义的恶性肿瘤

IF 0.3 Q4 INFECTIOUS DISEASES
J. Anejo-Okopi, H. Onywera, S. Omale, O. Audu
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引用次数: 0

摘要

恶性肿瘤是人类免疫缺陷病毒(HIV)感染患者发病和死亡的主要原因。由于采用了有效的抗逆转录病毒联合疗法,艾滋病毒感染已从被判死刑变成一种慢性病。非传染性疾病的相关发病率,尤其是卡波西氏肉瘤和非霍奇金淋巴瘤等癌症,由于抗逆转录病毒药物延长了生存期,重新引起了临床关注。现有证据表明,在艾滋病毒感染人群中,与细菌和病毒感染相关的癌症发病率越来越高。人们还关注艾滋病毒感染者出现癌症的病因、危险因素和病毒感染。护理人员面临的挑战是制定和实施有效的手段来筛查、治疗和预防艾滋病毒感染患者的非艾滋病决定性癌症(NADCs)。有必要为未感染者和符合条件的人群提供乙型肝炎病毒和人乳头瘤病毒疫苗。在健康教育中应强调这些非艾滋病界定的癌症,以便提高对发病率的认识,从而鼓励接受筛查,从而实现健康的生活和降低死亡率。这篇简短的综述旨在介绍NADCs、危险因素、微生物群的作用、诊断方法以及在艾滋病毒/艾滋病感染者中进行紧急筛查和预防的必要性。HIV / AIDS Rev 2021;20, 3: 151-157 DOI: https://doi.org/10.5114/hivar.2021.109648
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Non-AIDS defining malignancies among HIV-infected patients
Malignancies are a major cause of morbidity and mortality in human immunodeficiency virus (HIV)infected patients. With the introduction of an effective combination of antiretroviral therapy, HIV infection has been changed from being a death sentence to a chronic condition. There is renewed clinical interest in the associated morbidities of non-communicable diseases, and most importantly cancers, such as Kaposi’s sarcoma and non-Hodgkin’s lymphoma, due to prolonged survival on antiretrovirals. Available evidence suggests that there is an increasing frequency of cancers associated with bacterial and viral infections among the HIV-infected population. There is also a concern about the etiology of emergence of cancers, risk factors, and viral infections in HIV-infected individuals. The challenge is for the caregivers to develop and implement effective means to screen, treat, and prevent non-AIDS defining cancers (NADCs) in the HIV-infected patients. There is a need for provision of hepatitis B virus and human papillomavirus vaccines for those who are uninfected and the eligible population. Emphasis should be on these non-AIDS defining cancers during health education, in order to create awareness of the morbidity that may encourage screening uptake, thus resulting in healthy living and reduced mortality rates. This brief review aimed to bring to fore the account of NADCs, risk factors, the role of the microbiota, diagnostic methods, and the need for urgent screening and prevention among people living with HIV/AIDS. HIV AIDS Rev 2021; 20, 3: 151-157 DOI: https://doi.org/10.5114/hivar.2021.109648
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来源期刊
HIV & AIDS Review
HIV & AIDS Review INFECTIOUS DISEASES-
CiteScore
0.50
自引率
0.00%
发文量
30
审稿时长
12 weeks
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