Revista Peruana de Medicina de Experimental y Salud Publica最新文献

{"title":"Implementation of a SARS-CoV-2 genomic surveillance network as a strategy to face other health challenges in Peru.","authors":"Carlos Padilla-Rojas, Verónica Hurtado, Wendy Lizarraga, Víctor Jimenez-Vasquez, Iris S Molina, Luis Barcena-Flores, Alicia Nuñez, Nieves Sevilla, Steve V Acedo-Lazo, Estela Huamán-Angeles, Princesa Medrano, Kelly Izarra, Alexander Fajardo, Vanesa Dominguez, Karla Vasquez, Orson Mestanza, Francisco Ascue, Henri Bailon, Marco Galarza-Pérez, Omar Caceres-Rey, Roger V Araujo-Castillo, Natalia Vargas-Herrera, Joseph Huayra, Gloria Arotinco-Garayar, Priscila Lope-Pari, Johanna Balbuena-Torres, Nancy Rojas-Serrano","doi":"10.17843/rpmesp.2026.431.15048","DOIUrl":"10.17843/rpmesp.2026.431.15048","url":null,"abstract":"<p><p>We present a complete description of the implementation of SARS-CoV-2 genomic surveillance during the COVID-19 pandemic in Peru, and the impact of applying this technology to other pathogens important for the country's public health. This aims to highlight the achievements, challenges, and lessons learned that allow for strengthening the response to current and future health challenges at the national level, as well as public health decisions. With the genomic surveillance initiative led by the National Institute of Health, 48,691 SARS-CoV-2 genomes from all regions of the country have been sequenced from 2020 to 2024, achieving the identification of eight variants of the virus and the designation of 25 new lineages within the Gamma, Delta, and Omicron variants. Genomic surveillance of SARS-CoV-2 has allowed for the timely identification of variants of epidemiological interest, monitoring the evolution of the virus in real-time, and using this information as a tool for public health decision-making. This experience subsequently provided the basis for monitoring other pathogens that have caused health emergencies in Peru and the world, such as dengue, influenza, and mpox.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"110-118"},"PeriodicalIF":1.1,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ceftazidime-avibactam and aztreonam as a therapeutic alternative in two episodes of bacteremia due to Stenotrophomonas maltophilia after allogeneic hematopoietic stem cell transplantation: case report.","authors":"Wilder Bolaños-Vargas, Cesar Copaja-Corzo, Ivan Fernandez Vertiz, Alfredo Wong-Chang, Miriam Rut Baldeon Laureano","doi":"10.17843/rpmesp.2026.431.15393","DOIUrl":"10.17843/rpmesp.2026.431.15393","url":null,"abstract":"<p><p>Infection due to Stenotrophomonas maltophilia represents a therapeutic challenge in immunocompromised patients, especially during hematopoietic recovery after hematopoietic stem cell transplantation (HSCT). The use of trimethoprim-sulfamethoxazole (TMP-SMX), the first-line antimicrobial, is contraindicated due to its hematological toxicity. We present the case of a patient undergoing haploidentical HSCT who developed two episodes of bacteremia due to S. maltophilia on days +20 and +49. Given the contraindication of TMP-SMX due to severe myelosuppression, the combination of ceftazidime-avibactam and aztreonam was used as an alternative treatment, achieving clinical resolution in both episodes. The patient remained stable until day +100; however, he experienced graft failure and died on day +107 due to infection with Pseudomonas aeruginosa producing VIM-type carbapenemase. This case shows that the use of ceftazidi-me-avibactam plus aztreonam can be useful against S. maltophilia infections in post-HSCT patients with contraindications for the use of TMP-SMX.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"126-131"},"PeriodicalIF":1.1,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial excellence and impact on public health: a strategic look from scientific journals of the global south.","authors":"César Cabezas","doi":"10.17843/rpmesp.2026.431.16258","DOIUrl":"10.17843/rpmesp.2026.431.16258","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"4-5"},"PeriodicalIF":1.1,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245982/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the departmental availability of nutritionists and indicators of anemia and maternal-child malnutrition in Peru.","authors":"Jamee Guerra Valencia, Akram Hernández-Vásquez","doi":"10.17843/rpmesp.2026.431.15527","DOIUrl":"10.17843/rpmesp.2026.431.15527","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"143-145"},"PeriodicalIF":1.1,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Purple urine bag syndrome: report of an unusual case in a patient with a chronic urinary catheter.","authors":"Jorge Luis Hurtado-Alegre, Jhonatan Mauricio Crispin-Ayala, Jorge Del Piero Alvarez-Canto, Jhosef Franck Quispe-Pari","doi":"10.17843/rpmesp.2026.431.15050","DOIUrl":"10.17843/rpmesp.2026.431.15050","url":null,"abstract":"<p><p>Purple urine bag syndrome (PUBS) is an infrequent and generally asymptomatic condition characterized by the purple coloration of urine in patients with a urinary catheter, secondary to bacterial metabolism of tryptophan and the production of pigments. We describe the case of an 82-year-old male with a history of benign prostatic hyperplasia, arterial hypertension, and chronic Foley catheter use, who presented for a preoperative consultation without symptoms, exhibiting purple urine of 48 hours' duration. The urine culture showed growth of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae. Given the absence of urinary or systemic symptoms, it was decided not to administer antibiotics and to only replace the urinary drainage system. The patient progressed favorably, with resolution of the color change. PUBS, although striking, is a benign finding associated with asymptomatic bacteriuria, and its management should avoid unnecessary antibiotic use.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"138-142"},"PeriodicalIF":1.1,"publicationDate":"2026-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The triple cost of tobacco and sugary drinks: health, economy and the environment.","authors":"Andrea Alcaraz, Natalia Espinola","doi":"10.17843/rpmesp.2025.423.15560","DOIUrl":"10.17843/rpmesp.2025.423.15560","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"42 3","pages":"237-239"},"PeriodicalIF":1.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy contribution from ultra processed foods in peruvian children.","authors":"Marianella Miranda-Cuadros, Miguel Campos-Sánchez, Gustavo Cediel Giraldo, María Laura da Costa Louzada, Joaquín Alejandro Marrón-Ponce","doi":"10.17843/rpmesp.2025.423.14339","DOIUrl":"10.17843/rpmesp.2025.423.14339","url":null,"abstract":"<p><strong>Objective.: </strong>To evaluate the energy contribution of ultra-processed foods (UPFs) and its association with social and demographic covariates in children between 6 and 35 months of age, based on national surveys conducted in 2008‒2010, 2015‒2016, and 2019.</p><p><strong>Materials and methods.: </strong>The surveys used multistage stratified random samples. 24-hour recalls were applied on random days per participant, using the modified multiple-pass method, with the support of visual aids and scales. UPFs belonged to the Nova 4 group. Given the bimodal distribution, the covariates were analyzed using two models: a binomial model for the percentage of UPF consumers and a normal model for the average energy contribution, only among UPF consumers. The estimates and models were adjusted according to the sampling design.</p><p><strong>Results.: </strong>2887 children were included. UPFs contributed 27% (95% CI: 25 to 29) of the total energy intake and were consumed by 86% (84 to 89) of children. The main energy contribution from UPFs came from the milk and dairy products group (19% [17 to 20]) and cereals (5% [4 to 6]). The covariates associated with consumption were age, calendar quarter, and poverty. No associations were found with sex or the year of the survey.</p><p><strong>Conclusions.: </strong>In children aged 6 to 35 months in Peru, UPFs provided an average of 27% of total energy and were consumed by 86%. The main sources were the milk and dairy products, and the cereals group. UPF consumption was associated with age, poverty, and the calendar quarter.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"42 3","pages":"240-251"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depressive symptoms, violence, and discrimination among transgender women during the COVID-19 pandemic: a cross-sectional study.","authors":"Renato A Errea, Noris G Hernandez, Janeth Santa-Cruz, Carmen Contreras, Lourdes Ramos, Diego Rondón, Karen Ramos, Leyla Huerta, Leonid Lecca, Jesús Peinado","doi":"10.17843/rpmesp.2025.423.14287","DOIUrl":"10.17843/rpmesp.2025.423.14287","url":null,"abstract":"<p><strong>Objective.: </strong>To examine the frequency of depressive symptoms, gender-based violence, and gender-based discrimination among transgender women (TGW) in Lima, Peru, during the COVID-19 pandemic.</p><p><strong>Materials and methods.: </strong>Between May and July 2021, the non-governmental organization Socios En Salud conducted a cross-sectional study to assess depressive symptoms, gender-based discrimination and violence among TGW identified from a prior study database and peer referral. Descriptive statistics were used to report frequencies, and an exploratory bivariate analysis was performed to examine associations between depressive symptoms and participants´ characteristics, including experiences of discrimination and violence. Depressive symptoms were assessed using the Patient Health Questionnaire-9; gender-based discrimination and violence were measured using adopted instruments.</p><p><strong>Results.: </strong>A total of 112 participants were included in the study. Most TGW reported depressive symptoms (81.2%), experiences of gender-based violence (83.8%), and experiences of gender-based discrimination (95.5%). The presence of depressive symptoms was associated with experiences of discrimination in healthcare settings (p < 0.046) and with experiences of violence (p < 0.046).</p><p><strong>Conclusions.: </strong>A high frequency of depressive symptoms, as well as experiences of gender-based discrimination and violence, was observed among TGW in Lima, Peru, during the COVID-19 pandemic. In addition, significant associations were identified between these experiences and the presence of depressive symptoms. These findings are consistent with existing evidence on the mental health impact of the pandemic, but also suggest a disproportionate burden among TGW and highlight the urgent need to address the underlying contributing factors.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"42 3","pages":"281-290"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular identification of resistance to organophosphates and carbamates in Aedes aegypti of different physiological ages in a cemetery in Peru.","authors":"Rosa Elena Santillan-Valdivia, Mariano Manuel Yañez Cesti, Ruth Noemi Neyra-Palacios, Archi Alejandro Ruiz-Polo","doi":"10.17843/rpmesp.2025.423.14471","DOIUrl":"10.17843/rpmesp.2025.423.14471","url":null,"abstract":"<p><p>In 2024, a cross-sectional, quantitative, and descriptive study was conducted to molecularly identify resistance to organophosphates and carbamates in Aedes aegypti of different physiological ages in a cemetery in northern Peru. Female specimens were captured, taxonomically identified, their ovaries dissected, and the parity percentage calculated. Likewise, the legs of nulliparous, parous, and gravid females were dissected, DNA was extracted, and PCR was performed to detect the mutant ACEr gene associated with resistance to organophosphates and carbamates. A total of 218 (100%) females were captured, with a nulliparity index of 37,61% and a parity index of 62,39%, of which 13,23% of parous females were gravid at the time of capture. The ACEr gene was detected in all three physiological age groups. It is inferred that in the analyzed cemetery, there are Aedes aegypti populations carrying the genetic mutation conferring resistance to organophosphate and carbamate insecticides.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"42 3","pages":"312-317"},"PeriodicalIF":1.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homicides in Peru: the importance of accurate and timely recording of causes of death.","authors":"Akram Hernández-Vásquez, Luis Ttito-Paricahua, Richard Asmat-Condormango, Judith Quiñones-Inga","doi":"10.17843/rpmesp.2025.423.14947","DOIUrl":"10.17843/rpmesp.2025.423.14947","url":null,"abstract":"","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"42 3","pages":"328-330"},"PeriodicalIF":1.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12679969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}