Manuel Chavez-Ruiz, Ruddy Mesa-Landeo, Lenin Rueda-Torres, Betsabe Ruffner-Camargo, Sabir Khan
{"title":"Development of a voltammetric analytical method for the quantification of mercury in urine.","authors":"Manuel Chavez-Ruiz, Ruddy Mesa-Landeo, Lenin Rueda-Torres, Betsabe Ruffner-Camargo, Sabir Khan","doi":"10.17843/rpmesp.2026.431.14912","DOIUrl":"10.17843/rpmesp.2026.431.14912","url":null,"abstract":"<p><p>Exposure to mercury represents a critical challenge for public health, necessitating precise and portable analytical methods for biomonitoring. This experimental analytical study develops an analytical method and evaluates the performance of square wave anodic stripping voltammetry (SWASV) for the quantification of mercury in urine. For this purpose, the operating conditions of the SWASV system were optimized through tests with standard mercury solutions. Commercial urine (BIO-RAD®) pretreated with nitric acid was used. Linearity, precision, trueness, limit of detection (LOD), and limit of quantification (LOQ) were evaluated. The results showed high precision, with a relative standard deviation (%RSD) of 6.21. Furthermore, the trueness analysis revealed no significant differences between SWASV and the cold vapor atomic absorption (CVAA) method, p = 0.2601. The LOD and LOQ were 0.68 and 2.2 μg L-1, respectively. These findings suggest that SWASV is a precise method comparable to CVAA for the detection of mercury in urine under controlled laboratory conditions. Additional studies are required to evaluate its applicability in real population biomonitoring scenarios.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"77-82"},"PeriodicalIF":1.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dayli Mancilla-Pérez, Gabriela García-Morales, Cinthya Jennifer Rayón-Castañeda, Juan Manuel Sánchez-Rebolledo, Ricardo Gil-Ojeda, Josue Rosaliano-Salinas
{"title":"Characterization of dengue cases in a family medicine unit in Mexico.","authors":"Dayli Mancilla-Pérez, Gabriela García-Morales, Cinthya Jennifer Rayón-Castañeda, Juan Manuel Sánchez-Rebolledo, Ricardo Gil-Ojeda, Josue Rosaliano-Salinas","doi":"10.17843/rpmesp.2026.431.14939","DOIUrl":"10.17843/rpmesp.2026.431.14939","url":null,"abstract":"<p><p>The objective of this study was to describe the epidemiological and clinical characteristics of dengue cases treated at a family medicine unit in Guerrero, Mexico. A case series was conducted, including patients diagnosed with dengue between January and December 2023. Of a total of 596 cases, 91.8% presented with dengue without warning signs, 8.1% with warning signs, and 0.2% with severe dengue. Hospitalization was required for 2.7% of patients, and the case fatality rate was 0.2%. The most frequent symptoms were fever (98.2%), headache (79.7%), and myalgia (75.3%). Dengue serology was performed in 28.1% of cases, with a positivity rate of 37%. The clinical findings support its usefulness for timely diagnosis and therapeutic decision-making based on the severity of the illness; they also highlight the importance of early identification of warning signs by the population.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"90-97"},"PeriodicalIF":1.1,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Augusto Yabar, Karolyn Vega-Chozo, Eduardo Miranda-Ulloa, Flor de María Peceros-Pelaez, Manuel Terrazas-Aranibar, Adolfo Marcelo, María Paquita García, María Elena López, Rubén Vásquez, Katia Zúñiga, Haydee Alvarado, Renso López-Liñán, Heriberto Arévalo, Nancy Rojas-Serrano
{"title":"Viral co-infection with SARS-CoV-2 in hospitalized Peruvian patients during 2020-2021.","authors":"Carlos Augusto Yabar, Karolyn Vega-Chozo, Eduardo Miranda-Ulloa, Flor de María Peceros-Pelaez, Manuel Terrazas-Aranibar, Adolfo Marcelo, María Paquita García, María Elena López, Rubén Vásquez, Katia Zúñiga, Haydee Alvarado, Renso López-Liñán, Heriberto Arévalo, Nancy Rojas-Serrano","doi":"10.17843/rpmesp.2026.431.15162","DOIUrl":"10.17843/rpmesp.2026.431.15162","url":null,"abstract":"<p><p>The study aimed to identify coinfections of SARS-CoV-2 with other viruses in patients with moderate and severe COVID-19. 98 patients from Lima, San Martín, and Loreto were selected, from whom nasopharyngeal secretion, blood, and urine samples were taken and analyzed using serological and molecular tests to detect HTLV, HIV, hepatitis B, dengue, Chikungunya, Zika, and a panel of respiratory viruses (influenza A/B, rhinovirus, respiratory syncytial virus, metapneumovirus, and adenovirus). The results showed two cases of coinfection (2/98; 2%): one with SARS-CoV-2/rhinovirus and another with SARS-CoV-2/HTLV-2. Both patients presented with COVID-19-associated pneumonia but progressed favorably. It is concluded that the frequency of viral coinfection in patients from health facilities in the Peruvian coast and jungle with moderate and severe cases of COVID-19 was low.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"104-109"},"PeriodicalIF":1.1,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edert Abel Samame-Caramutti, Luis Salcedo-Valdez, Silvia Suárez-Cunza
{"title":"In vitro antioxidant and anti-inflammatory activities and total polyphenol and flavonoid contents of Anadenanthera colubrina from northern Peru.","authors":"Edert Abel Samame-Caramutti, Luis Salcedo-Valdez, Silvia Suárez-Cunza","doi":"10.17843/rpmesp.2026.431.15207","DOIUrl":"10.17843/rpmesp.2026.431.15207","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the in vitro antioxidant and anti-inflammatory activity of the hydroethanolic extract of the bark of Anadenanthera colubrina from northern Peru, as well as its total polyphenol (TPC) and flavonoid (TFC) contents.</p><p><strong>Materials and methods: </strong>Antioxidant activity was evaluated using chemical assays for 2,2-diphenyl-1-picrylhydrazyl (DPPH●) radical scavenging and ferric reducing antioxidant power (FRAP), as well as by measuring lipid peroxidation (formation of thiobarbituric acid reactive substances, TBARS) and H2O2-induced hemolysis. Anti-inflammatory activity was determined through heat-induced ovalbumin denaturation and hypotonicity-induced hemolysis assays.</p><p><strong>Results: </strong>The extract showed high antioxidant activity in both the DPPH●radical scavenging assay (747.6 mg Trolox equivalents/gram of dry extract) and the FRAP assay (435.9 mg FeSO4 equivalents/gram of dry extract). The extract (50 to 1000 μg/mL) inhibited lipid peroxidation, H2O2-induced hemolysis, and ovalbumin denaturation. No activity was observed in the hypotonicity-induced hemolysis assay. TPC and TFC were 642.7 mg gallic acid equivalents/gram and 416.2 mg catechin equivalents/gram of dry extract, respectively.</p><p><strong>Conclusions: </strong>These activities were reported for the first time for A. colubrina from northern Peru, suggesting that the hydroethanolic extract of A. colubrina bark possesses significant preliminary in vitro antioxidant and anti-inflammatory properties and that the high polyphenol and flavonoid contents may be responsible, at least partially, for these activities.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"51-60"},"PeriodicalIF":1.1,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Candida species identified by MAL-DI-TOF and antifungal susceptibility in hospitalized patients with COVID-19 in Peru.","authors":"Rolando Paredes-Gago, Sorell Alvarado-Vela, Clelia Céspedes-Román","doi":"10.17843/rpmesp.2026.431.15685","DOIUrl":"10.17843/rpmesp.2026.431.15685","url":null,"abstract":"<p><strong>Objectives: </strong>To identify Candida species using MALDI-TOF and analyze their antifungal susceptibility from Candida genus isolates in hospitalized patients with COVID-19 between November 2020 and April 2022.</p><p><strong>Materials and methods: </strong>An observational, descriptive, and cross-sectional study based on the se-condary analysis of microbiological and clinical-epidemiological data from 260 Candida isolates, primarily from urine, respiratory secretions, and blood cultures, referred to the National Reference Laboratory of Mycology of the National Institute of Health. Identification was performed using phenotypic techniques and MALDI-TOF, and antifungal susceptibility was evaluated using disk diffusion and broth microdilution according to Clinical and Laboratory Standards Institute (CLSI) criteria.</p><p><strong>Results: </strong>Candida albicans was the most prevalent species (64.6%), followed by Candida tropicalis, Candida glabrata, Candida parapsilosis, and Candida auris. Most isolates showed susceptibility to voriconazole and caspofungin, while varying percentages of susceptibility to fluconazole were observed, especially in C. glabrata and C. auris. Minimum inhibitory concentration (MIC) values showed variability between species and antifungals.</p><p><strong>Conclusions: </strong>Non-albicans species represented a considerable proportion of the analyzed isolates. These findings descri-be the pattern of species and antifungal susceptibility in strains referred to the National Reference Labora-tory of Mycology of the National Institute of Health during the COVID-19 pandemic.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"16-26"},"PeriodicalIF":1.1,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brendy Alcira Padilla-Obregón, Iván Benavides-Céspedes, Yeisson Cera-Vallejo, Daisy Lozano-Arias, Carlos Mario Meléndez, Roberto Garcia-Alzate
{"title":"Detection of Trypanosoma spp. and Leishmania spp. in bats from the department of Atlantico, Colombia.","authors":"Brendy Alcira Padilla-Obregón, Iván Benavides-Céspedes, Yeisson Cera-Vallejo, Daisy Lozano-Arias, Carlos Mario Meléndez, Roberto Garcia-Alzate","doi":"10.17843/rpmesp.2026.431.15494","DOIUrl":"10.17843/rpmesp.2026.431.15494","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the frequency of Trypanosoma spp. and Leishmania spp. infection in bats captured in the municipalities of Piojó, Tubará, and Usiacurí, in the department of Atlántico, in the northern Colombian Caribbean region.</p><p><strong>Materials and methods: </strong>Between August 2022 and April 2023, bats were captured using mist nets; these were taxonomically identified, and their sex, reproductive stage, and relative age were established. Blood samples were obtained from the brachial vein. The identification of Trypanosoma spp. was performed through parasitological and molecular diagnosis; DNA was extracted, and the kinetoplast region (kDNA) was amplified. For the identification of Leishmania spp., the β-tubulin region was amplified.</p><p><strong>Results: </strong>From 110 bats analyzed, an overall infection frequency of 14.50% (16/110) was determined. The presence of Trypanosoma spp. was detected in 14.50% (16/110) of the individuals and Leishmania spp. in 10.00% (11/110). Coinfection was identified in 11 specimens, equivalent to a frequency of 10.00% of the total sample. The coinfected bats belonged to the species Artibeus lituratus, Artibeus jamaicensis, and Phyllostomus hastatus.</p><p><strong>Conclusions: </strong>This study constitutes the first report on the frequency of trypanosomatid coinfection in bats from the department of Atlántico.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"6-15"},"PeriodicalIF":1.1,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adherence to antihypertensive treatment in patients at a tertiary hospital in Lima, Peru.","authors":"Angy Aguilar-Lizarme, José Amado-Tineo","doi":"10.17843/rpmesp.2026.431.15462","DOIUrl":"10.17843/rpmesp.2026.431.15462","url":null,"abstract":"<p><p>In Peru, there are few reports on pharmacological adherence in patients with arterial hypertension. In this context, the present study aimed to determine adherence to antihypertensive treatment in patients treated at a tertiary-level social security hospital in Lima. A cross-sectional study was conducted in 250 hospitalized patients, over 18 years of age, with a diagnosis of primary arterial hypertension on pharmacological treatment. Adherence was evaluated using the Morisky questionnaire (MMAS-8), and variables such as prescribed medication, age, sex, marital status, and educational level were collected. 56.4% of the participants were male and 86.4% were over 60 years old. It was observed that 42% presented low pharmacological adherence and 58% medium adherence, with no cases of high adherence recorded. Monotherapy was the most frequent regimen (48%), with losartan, nifedipine, and enalapril being the most prescribed drugs. Finally, significant differences were identified between adherence to antihypertensive treatment and educational level and the number of drugs.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"98-103"},"PeriodicalIF":1.1,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodrigo Robles-Mariños, Diego Fano-Sizgorich, Germán F Alvarado, Gustavo F Gonzales
{"title":"Altitude and case fatality rate from COVID-19 during the pandemic in Peru, 2020-2022.","authors":"Rodrigo Robles-Mariños, Diego Fano-Sizgorich, Germán F Alvarado, Gustavo F Gonzales","doi":"10.17843/rpmesp.2026.431.14979","DOIUrl":"10.17843/rpmesp.2026.431.14979","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the functional form of the association between the district altitude of residence and the case fatality rate of COVID-19 cases in Peru during the 2020-2022 period.</p><p><strong>Materials and methods: </strong>A retrospective cohort study was conducted using secondary data from the Ministry of Health of Peru on COVID-19 cases and deaths. District altitude of residence was categorized into four groups (0-500; 501-2,000; 2,001-3,500; and ≥3,501 masl). The outcome was death from COVID-19 according to the official death registry. Poisson regression was used to estimate adjusted relative risks for individual and contextual variables, using robust variance clustered by district. The analyses were repeated according to the five epidemic waves that occurred between March 2020 and December 2022.</p><p><strong>Results: </strong>A non-linear association was observed between the altitude of residence and death from COVID-19, consistent with a \"U-shaped\" pattern, characterized by a lower risk of death in cases residing between 2,001 and 3,500 masl compared to those residing between 0 and 500 masl. This pattern remained consistent in the analyses stratified by epidemic wave.</p><p><strong>Conclusions: </strong>In Peru, during the 2020-2022 period, the data do not support a monotonic decrease in the risk of death from COVID-19 with increasing altitude of residence. On the contrary, the results suggest a non-linear relationship, with lower lethality at intermediate altitudes (2,001-3,500 masl).</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"27-40"},"PeriodicalIF":1.1,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yeisson Cera-Vallejo, Claudia Romero-Vivas, Andrew K Falconar, Roberto García-Alzate, Daisy Lozano-Arias
{"title":"Circulation of Trypanosoma cruzi TcI in wild populations and those with a tendency toward domiciliation of Panstrongylus geniculatus (Latreille, 1811) (Hemiptera; Reduviidae) in the department of Atlántico, Colombia.","authors":"Yeisson Cera-Vallejo, Claudia Romero-Vivas, Andrew K Falconar, Roberto García-Alzate, Daisy Lozano-Arias","doi":"10.17843/rpmesp.2026.431.15385","DOIUrl":"10.17843/rpmesp.2026.431.15385","url":null,"abstract":"<p><p>The TcI genotype of Trypanosoma cruzi was identified in wild populations and those with a tendency toward domiciliation of Panstrongylus geniculatus in the department of Atlántico, Colombia. Through active searching and light traps in rural and urban areas of three municipalities, 33 specimens of P. geniculatus were captured: Usiacurí (2), Piojó (2), and Tubará (29), the latter collected in five households. DNA from the digestive content was analyzed by PCR using molecular markers (DNAk, Mini-Exon, 18S, DNAr). Infection by T. cruzi was evidenced in 75% of the specimens (25/33), all from Tubará, with exclusive identification of the TcI genotype. Additionally, entomological indices were calculated, with infestation, colonization, and natural infection indices of 60%, 33%, and 86%, respectively. These findings constitute the first report of T. cruzi TcI in the department of Atlántico and the first record of P. geniculatus in Usiacurí, highlighting a potential risk to Colombian public health.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"83-89"},"PeriodicalIF":1.1,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mayra Meza-Hernández, Kiomi Yabiku-Soto, Francisco Diez-Canseco
{"title":"Supply and advertising of food and beverages with front-of-package warning labeling in schools of Metropolitan Lima 2023.","authors":"Mayra Meza-Hernández, Kiomi Yabiku-Soto, Francisco Diez-Canseco","doi":"10.17843/rpmesp.2026.431.15249","DOIUrl":"10.17843/rpmesp.2026.431.15249","url":null,"abstract":"<p><strong>Objectives: </strong>To describe the supply and advertising of food and beverages with front-of-package warning labeling in kiosks and cafeterias, and in school environments of public and private schools in Metropolitan Lima.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted in 45 schools in Metropolitan Lima between March and May 2023. The supply and advertising of food and beverages were observed in school kiosks during the school day and among street vendors located at the school exit gates.</p><p><strong>Results: </strong>A total of 57 school kiosks and cafeterias from 45 schools were analyzed. Processed and ultra-processed foods and beverages were observed in 96.5% of them, and at least one product with front-of-package warning labeling (octagon) was identified in 89.5%. Street vendors were found at 41 schools, totaling 148 vendors. Processed and ultra-processed food and beverages were observed in 77.7% of them, and at least one food or beverage with an octagon was observed in 48.6%. Advertising for processed and ultra-processed foods was observed in 57.9% of school kiosks and cafeterias and in 27.7% of street vendors.</p><p><strong>Conclusions: </strong>Evidence shows the exposure of schoolchildren to unhealthy food environments and non-compliance with regulations prohibi-ting the sale of foods with octagons both inside and around schools. It is necessary to reinforce information, awareness, and monitoring of the educational community to ensure the effectiveness of these policies in protecting the health of schoolchildren.</p>","PeriodicalId":53651,"journal":{"name":"Revista Peruana de Medicina de Experimental y Salud Publica","volume":"43 1","pages":"41-50"},"PeriodicalIF":1.1,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13245979/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148426333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}