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Risk Factors Analysis in Recurrent Stroke Events: Literature Review 复发性中风事件的风险因素分析：文献综述

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17428

Adinda Sayeeda, Agianto Agianto, Rismia Agustina, Ichsan Rizany

{"title":"Risk Factors Analysis in Recurrent Stroke Events: Literature Review","authors":"Adinda Sayeeda, Agianto Agianto, Rismia Agustina, Ichsan Rizany","doi":"10.20527/jbk.v19i2.17428","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17428","url":null,"abstract":"After the first stroke, according to epidemiological data, there is a 30% risk of recurrent stroke. That events are the population who had suffered stroke and the recurrence rate is 9 times compared to the normal population. Results of research from the Stroke Association stated that the possibility of recurrence stroke was 3.1% in 30 days, 11.1% within one year, 26.4% within five years, and 39.2% within 10 years. This literature review is intended to analyze the risk factors of recurrent stroke events. The literature review was carried out by searching for articles in 2011-2021 in Indonesian and English. There were four databases for providing electronic journal articles, namely Garuda, Google Scholar, Science Direct, and PubMed. The quality of the articles carried out using JBI's Critical Appraisal Tools. Narrative synthesized was used to analyze the data of the review. There were 6 articles synthesized in this review. The review result showed that diabetes mellitus, hypertension, cardiovascular disorders, anemia, obesity, lack of physical activity, high serum of LDL/HDL, non-adherence to treatment, lack of confidence in treatment, lack of knowledge about the disease, and gender can encourage the occurrence of recurrent stroke. Many factors cause recurrent stroke events but diabetes mellitus, hypertension and non-adherence to treatment are most widely discussed in the six articles.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Isothiocyanate Therapy on Apoptosis of Trophoblast Cells in Pregnant Rats Hyperglycemia Atmosphere 异硫氰酸酯治疗对妊娠高血糖大鼠滋养细胞凋亡的影响

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15709

H. Gondo, Elizabteh Haryanti

{"title":"Effect of Isothiocyanate Therapy on Apoptosis of Trophoblast Cells in Pregnant Rats Hyperglycemia Atmosphere","authors":"H. Gondo, Elizabteh Haryanti","doi":"10.20527/jbk.v19i1.15709","DOIUrl":"https://doi.org/10.20527/jbk.v19i1.15709","url":null,"abstract":"Abstract: One of the factors that influence the complications of pregnancy and childbirth is diabetes mellitus. In this study, it was intended to create experimental diabetic conditions in experimental white rats with the administration of aloksan for 5 days. A total of 30 mice were checked for sugar levels on day 7 after inducing alloxane to see that the mice were already in a hyperglycemic state. Then divided into 6 groups, each group there are 5 white pregnant rats. Group 1 was the negative group (without being given aloksan), group 2 was positive group (given aloksan as much as 150 mg / day / kg BB), groups 3, 4, 5 and 6 were given Aloksan 150mg / day / kg and each was given simultaneously isothiocyanates with a dose of 0.1; 0,2; 0.4 and 0.8 mg/day/kg BB. DNA fragmentation is one of the characteristics of apoptosis. In this study DNA fragmentation was examined by the TUNEL method (Terminal deoxynucleotidyl Transferase-mediated dUTP Nick End Labeling). The average number of trophoblast cells in white pregnant rats hyperglycemia that experienced apoptosis decreased as the dose of isotiocyanate therapy increased in rats that had been induced by alloxane. And the best dose is at a dose of 0.8 mg / day / kg BB.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41841988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total Sleep Deprivation Reduces Quality of Spermatozoa in Male Albino Rat (Rattus norvegicus) 完全睡眠剥夺降低雄性白化大鼠（褐家鼠）精子质量

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15719

F. Arjadi, Sindhu Wisesa, V. Indriani

{"title":"Total Sleep Deprivation Reduces Quality of Spermatozoa in Male Albino Rat (Rattus norvegicus)","authors":"F. Arjadi, Sindhu Wisesa, V. Indriani","doi":"10.20527/jbk.v19i1.15719","DOIUrl":"https://doi.org/10.20527/jbk.v19i1.15719","url":null,"abstract":"Abstract: Sleep deprivation-induced stress decreases the quality of spermatozoa due to the increase of glucocorticoid levels through the hypothalamic-pituitary-adrenal axis. Sleep recovery (SR) restores the effect of stress due to sleep deprivation by decreasing lipid peroxides and other free radicals and increasing glutathione antioxidants. This study aims to determine the spermatozoa quality in male albino rats (Rattus norvegicus) after the stress induction by diverse sleep deprivation protocols. This study is experimental research with posttest-only control group design in 30 male albino rats divided into five groups consisting of group I for negative control (no induction of sleep deprivation), group II for paradoxical sleep deprivation (PSD), group III for total sleep deprivation (TSD), group IV for PSD followed by SR, and group V for TSD followed by SR. PSD and TSD were performed by depriving rats sleep for 20 and 24 hours/day, respectively, for five days. SR was done for the next five days after PSD or TSD. Shapiro-Wilk test was used for normality of data distribution, and Levene's test was used for variance homogeneity. Comparative hypothesis was then analyzed with One Way Analysis of Variance (ANOVA) test, and significance between groups was analyzed with Tukey's Post-Hoc test. Group III (TSD) demonstrated the lowest mean of spermatozoa count (41,53±2,29), spermatozoa morphology (13,00±2,91), spermatozoa viability (31,00±7,39), and percentage of motility rate (37±8,58%) among all groups. In conclusion, total sleep deprivation (TSD) decreases the quality of spermatozoa in male albino rats (Rattus norvegicus).","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49484018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total Flavonoids Determination and Antioxidant Activity of Ethyl Acetate, Ethanol, and Methanol Extracts from Seluang Belum Root (Luvunga sarmentosa (Blume) Kurz.) 紫藤乙酸乙酯、乙醇、甲醇提取物总黄酮含量测定及抗氧化活性研究

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15733

N. Wathan, M. Rizki, Amalia Khairunnisa, Hilneser Simamora

{"title":"Total Flavonoids Determination and Antioxidant Activity of Ethyl Acetate, Ethanol, and Methanol Extracts from Seluang Belum Root (Luvunga sarmentosa (Blume) Kurz.)","authors":"N. Wathan, M. Rizki, Amalia Khairunnisa, Hilneser Simamora","doi":"10.20527/jbk.v19i1.15733","DOIUrl":"https://doi.org/10.20527/jbk.v19i1.15733","url":null,"abstract":"Abstract: Flavonoids are phenolic compounds from nature that found in almost all parts of the plants. Seluang belum (Luvunga sarmentosa (Blume) Kurz.) root is one of the medicinal plants used by Dayak people in Central and South Kalimantan where in previous studies its part was contains flavonoids. This study aims to evaluate the best solvent for extracting flavonoid content and antioxidant activity using ethanol, methanol and ethyl acetate. The antioxidant activity performed by in vitro technique by DPPH assay. Total flavonoids content on the extracts of L. sarmentosa root determined using UV-Vis spectrophotometric with aluminium chloride method and calculated as quercetin equivalents (QE). The results showed the highest antioxidant activities confirmed for the methanol extract (IC50 = 80.33 ppm). The highest of total flavonoids contents was recorded for the ethanol extract (6.56 ± 0.006% w/w Quercetin Equivalent). The results showed that treatment effect of different solvent extraction was significant (sig <0.05) on total flavonoid and antioxidant activities from L. sarmentosa root.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47492079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between C-Reactive Protein Levels, Lactate Dehydrogenase, and Neutrophil-to-Lymphocyte Ratio with Coronavirus Disease 2019 Severity c反应蛋白水平、乳酸脱氢酶和中性粒细胞与淋巴细胞比例与2019冠状病毒病严重程度的关系

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15718

Hendra Nur'amin, I. N. Suarjana, M. Rudiansyah, Nanang Miftah Fajari, Djallalluddin Djallalluddin

{"title":"Relationship between C-Reactive Protein Levels, Lactate Dehydrogenase, and Neutrophil-to-Lymphocyte Ratio with Coronavirus Disease 2019 Severity","authors":"Hendra Nur'amin, I. N. Suarjana, M. Rudiansyah, Nanang Miftah Fajari, Djallalluddin Djallalluddin","doi":"10.20527/jbk.v19i1.15718","DOIUrl":"https://doi.org/10.20527/jbk.v19i1.15718","url":null,"abstract":"Abstract: Risk stratification of Coronavirus disease 2019 (COVID-19) patients is very important to determine patient care and prognosis. The reliable parameters include C-reactive protein (CRP), lactate dehydrogenase (LDH), and neutrophil-lymphocyte ratio (NLR). This study aimed to determine the relationship between CRP, LDH, and NLR levels with the severity of COVID-19 patients. An observational study with a cross-sectional approach was conducted at Ulin Hospital Banjarmasin on 91 eligible subjects. A logistic regression test was conducted to determine the relationship between variables and the severity of COVID-19. The results showed that there was no significant relationship between CRP levels and the severity of COVID-19 (prevalence odds ratio (POR) 0.85, 95% confidence interval (CI 95%) 0.34-2.09, p=0.72). There was a significant difference between the mean LDH levels in severe COVID-19 compared to non-severe COVID-19 (1006 + 601.77 vs 543.5 + 480.41, p<0.001), with POR 4.23, 95% CI 95% 1.56-11.45, p=0.005; there was also a significant difference between the mean NLR values in severe COVID-19 compared to non-severe COVID-19 (9.01 + 6.32 vs 5.38 + 5.03, p=0.002) with POR of 12.21 CI 95% 3.80-39.31, p<0.001. This study showed that LDH levels and NLR values were important predictors of COVID-19 severity.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41564520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute Toxicity Test of Toman Fish Extract on Erythrocyte Number and Hemoglobin Level in Normal and Diabetic Wistar Rat Model 番茄鱼提取物对正常和糖尿病Wistar大鼠红细胞数和血红蛋白水平的急性毒性试验

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15703

A. N. Carabelly, Beta Widya Oktiani, Nurashfia Nurashfia, M. L. Apriasari, D. Puspitasari

{"title":"Acute Toxicity Test of Toman Fish Extract on Erythrocyte Number and Hemoglobin Level in Normal and Diabetic Wistar Rat Model","authors":"A. N. Carabelly, Beta Widya Oktiani, Nurashfia Nurashfia, M. L. Apriasari, D. Puspitasari","doi":"10.20527/jbk.v19i1.15703","DOIUrl":"https://doi.org/10.20527/jbk.v19i1.15703","url":null,"abstract":"Abstract: Patients with diabetes mellitus (DM) may experience vascular impairment, wounds that emerged from dental practice require special attention in people who suffer from DM. Toman fish has the potential as an alternative medicine to accelerate the healing process in normal and diabetic wound. Erythrocyte and hemoglobin are two components of blood profile which can be used as the parameter to identify the effect of material toxicity. This study aims to test the acute toxicity of Toman fish extract at 16 mL/Kg BW dosage on the number of erythrocyte and the level of hemoglobin in normal and diabetic Wistar rat model after 14 days treatment. This is a true experimental study with post-test only and control group design. Samples were comprised of 21 male Wistar rats allocated to three different groups; normal rats given Toman fish extract (A), diabetic rats given Toman fish extract (B), and diabetic rats given BR2 feed only (C). The results showed that in group A, the number of erythrocytes was 8.67x106/mm3 and the level of hemoglobin was 17.30 g/dL. In group B, the number of erythrocytes was 7.39x106/mm3 and the level of hemoglobin was 16.32 g/dL. In group C, the erythrocyte number was 4.88x106/ mm3 and the hemoglobin level was 11.54 g/dL. It can be concluded that Toman fish extract at the dosage of 16 mL/Kg BW after 14 days administration is not toxic which was indicated by erythrocyte number and hemoglobin level in the blood of normal and diabetic Wistar rats models.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48601754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification Risk Factors of Stroke: Literature Review 卒中危险因素的识别:文献综述

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15728

Agianto Agianto, Bellia Yulise, Rismia Agustina, Ichsan Rizany

{"title":"Identification Risk Factors of Stroke: Literature Review","authors":"Agianto Agianto, Bellia Yulise, Rismia Agustina, Ichsan Rizany","doi":"10.20527/jbk.v19i1.15728","DOIUrl":"https://doi.org/10.20527/jbk.v19i1.15728","url":null,"abstract":"Abstract: State spending to deal with stroke is quite large every year due to the high incidence of stroke. Data from the Ministry of Health of Indonesia mentions an increasing number in health financing every year, the country financed stroke services by 2.56 trillion in 2018. The magnitude of the incidence of stroke can be lowered by controlling the risk factors of stroke. This study aimed to identify stroke risk factors, both those modifiable risk factors and irreversible risk factors. Research is conducted with a literature review using descriptive study methods or correlation analysis with cross sectional approaches. Sixteen articles identified from Google scholars and Garuda databases in the 2015-2020 range, and were analysed using JBI critical appraisal tools-checklist for analytical cross-sectional studies and JBI critical appraisal tools-checklist for prevalence studies. Synthesis narrative was used to analyse the articles. Out of 16 articles examined the modifiable risk factors were hypertension, dyslipidemia, diabetes mellitus, lack of physical activity, blood sugar levels, cholesterol levels in blood, alcohol and drug consumption, kidney disease, tuberculosis, heart disease, heart failure, obesity, central obesity, atrial fibrillation and also smoking are declared associated with the incidence of stroke. The irreversible risk factors are age, gender, education, family history, income employment, previous stroke history, and rural and urban distribution. Risk factors divided into two categories modifiable risk factors and irreversible risk factors. It is important to know the risk factors of stroke in order prevent the occurrence of stroke as early as possible by avoiding modifiable stroke risk factors. Hypertension, smoking, diabetes mellitus obesity, dyslipidemia, and lack of activity are the most modifiable stroke risk factors identified in the articles. The most irreversible risk factors identified in the article are age, gender, and level of education.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135778103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The 24-Hours Food Recall System for Monitoring Diabetes Melitus Patients 糖尿病患者24小时食品召回监测系统

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15704

Framita Rahman, Ika Nurlaili Isnaniyah, Mutiara Cyesa P Ngandoh, W. Saputri, Puspa Akhlakul Karimah

引用次数: 0

Berg Balance Scale (BBS) for Early Detection of Fall Risk in the Elderly in the Work Area of Antang Health Center Makassar City Berg平衡量表（BBS）用于望加锡市安唐卫生中心工作区老年人跌倒风险的早期检测

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15707

Siti Rahmani, T. Handayani

引用次数: 0

The Association Between Camellia sinensis Tea Consumption and Reduced Risk of Anxiety Disorder for Covid-19 Survivors: A Cross-Sectional Study among Medical Students 茶树茶消费与降低Covid-19幸存者焦虑障碍风险之间的关系:一项医科学生的横断面研究

Berkala Kedokteran Pub Date : 2023-02-28 DOI: 10.20527/jbk.v19i1.15710

M. Bakhriansyah, Vina Yulia Anhar, Sidnan Naufa Sulaiman, Faishal Muhammad Arrosyad

引用次数: 0