Berkala Kedokteran最新文献

Coefficient Test of Antimicrobial Phenol Combination of Eichhornia crassipes and Pistia stratiotes Extract In Vitro as Alternative Disinfection Candidates 蟋蟀草和地肤子提取物的抗菌酚组合作为替代消毒候选物质的体外系数测试

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17409

L. Budiarti, Siti Kaidah, Nazla Puteri Azhari, Putri Putri

{"title":"Coefficient Test of Antimicrobial Phenol Combination of Eichhornia crassipes and Pistia stratiotes Extract In Vitro as Alternative Disinfection Candidates","authors":"L. Budiarti, Siti Kaidah, Nazla Puteri Azhari, Putri Putri","doi":"10.20527/jbk.v19i2.17409","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17409","url":null,"abstract":"Eichhornia crassipes and Pistia stratiotes are weeds that often pollute water areas. These two contain various active compounds that act as antimicrobials, which have the potential as disinfection agents to prevent the transmission of pathogenic bacteria and fungi. An antimicrobial substance is said to be effective as a good disinfectant if it has a phenol coefficient value equal to or more than the 5% phenol comparison substance. The aim of this research was to test the effectiveness of a combination of Eichhornia crassipes and Pistia stratiotes extracts as a disinfection candidate through the phenol coefficient test. This in vitro experimental study was carried out using a dilution technique. The combination treatment of Eichhornia crassipes and Pistia stratiotes extracts and 5% phenol was tested against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhi and also Candida albicans yeast. Observations on the test media suspension tubes that were clear or did not show the growth of the test microbes for a period of 5, 10, and 15 minutes. The phenol coefficient value of the combination treatment of Eichhornia crassipes and Pistia stratiotes extracts was ≥1 with 5% phenol as comparison. Higher coefficient values were obtained for Staphylococcus aureus, equivalent values of 5% phenol were found for E.coli, P.aeruginosa, and C.albicans; whereas in S.typhi the value is <1. The combination treatment of E.crassipes and P.stratiotes extracts resulted in a phenol coefficient value equivalent to that of 5% phenol comparator, for several tested bacteria and yeasts. So it has effectiveness as a preparation for disinfection. The combination of Eichhornia crassipes and Pistia stratiotes extracts has antimicrobial effectiveness and can be developed as an alternative disinfection candidate.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Wetland Geography on the Prevalence of Diabetes Mellitus in South Kalimantan 湿地地理对南加里曼丹糖尿病患病率的影响

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17387

Nanang Miftah Fajari, Hendra Nur'amin

{"title":"The Effect of Wetland Geography on the Prevalence of Diabetes Mellitus in South Kalimantan","authors":"Nanang Miftah Fajari, Hendra Nur'amin","doi":"10.20527/jbk.v19i2.17387","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17387","url":null,"abstract":"Diabetes mellitus (DM) is a high-burden disease in Indonesia especially in South Kalimantan Province. South Kalimantan province lies in mostly wetlands areas. Identification of risk factors related to DM is necessary to prevent the disease. We conducted this study to assess the prevalence of DM in the South Kalimantan people, the impact of a wetlands area on DM prevalence, and other significant risk factors. A cross-sectional study approach was used to identify significant risk factors. We used adjusted multiple logistic regression to assess the association between risk factors and DM prevalence. There were 4612 subjects more than 18 years old in this study with 6.5% of them diagnosed as DM. Most of the subjects live in wetlands area (79.1%) and most of them >40 years old. Several important risk factors associated with DM were identified. Subjects in wetlands have a lower risk of DM compared to non-wetlands area (OR 0.73, CI 95%; 0.43-0.71, p<0.001). Age >40 years old increase the risk of DM (OR 2.24, CI 95 % 1.61-3.10, p<0.001), hypertension (OR 1.65, CI 95% 1.23-2.21, p<0,001), waist circumference >90 cm (OR 2.12, CI 95%. p<0.001), cholesterol level (>200 mg/dl) with DM prevalence (OR 1.38, CI 95% 1.02-1.87, p<0.04) and family history of DM (OR 10.28, CI 95% 7.67-13.76, p<0.001). This study found that wetlands areas may reduce the DM prevalence and other risk factors may increase the prevalence of DM. Further research is necessary to establish the relationship between wetlands area and DM.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Description of Social Media Use and Self-Esteem of Adolescents in Makassar City 马卡萨市青少年社交媒体使用情况和自尊描述

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17401

Framita Rahman, Brigita Sri Jane, M. C. P. Ngandoh, W. Saputri, Puspa Akhlakul Karima Tuhelelu

{"title":"Description of Social Media Use and Self-Esteem of Adolescents in Makassar City","authors":"Framita Rahman, Brigita Sri Jane, M. C. P. Ngandoh, W. Saputri, Puspa Akhlakul Karima Tuhelelu","doi":"10.20527/jbk.v19i2.17401","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17401","url":null,"abstract":"Adolescence is a crucial period of time and very challenging period. There is an increase concern on how social media use and mental health of teenagers. In Makassar City, there is a high number of mental health in adolescence yet still rare research has been conducted to investigates about social media use and self-esteem on teenagers. The aim of this study is to give a description on how adolescence behaviour on social media use and their level of self-esteem. This research uses a quantitative study with descriptive study design. The participant was selected based on some inclusion criteria such as teenagers’ age 16-18 years old, able to speak Bahasa, stay in Makassar City and willingly to become participant. The participant was determined by using non-probability sampling using convenience sampling method. There are 118 participants on this research. Three types of instruments were used; demography questionnaire, intensity of social media use and Rosenberg Self-Esteem Scale. From 118 participants, 19 were male and 99 were female. There are 42 respondents spend more than 6 hours on social media, and 54 respondents spend 2-6 hours on social media per day. Most of the respondents use their social media for see feed (20%), give like (14%), stalking (9%), news sharing (9%) and give comment (6%). Most of the respondents have high social media use (70 respondents) and low self-esteem (66 respondents). Social media use is quite high among teenagers in Makassar City and the self-esteem is mostly low. Thus, it is important to investigate the relationship of social media use and self-esteem so that it can give a comprehensive understanding on adolescence’s mental health and wellbeing in Makassar City","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential of Chemical Compounds from Coloring Plants (Stenochlaena palutris) as Competitors for ALK Protein Damage Due To Pesticide Exposure: In Silico Study 来自着色植物（Stenochlaena palutris）的化学物质作为农药暴露导致的 ALK 蛋白损伤的竞争者的潜力：硅研究

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17415

Sarmila Sarmila, Nafisah Nafisah, Hanna Habibah, Indah Saputri, Indah Setiawati, N. Komari

{"title":"Potential of Chemical Compounds from Coloring Plants (Stenochlaena palutris) as Competitors for ALK Protein Damage Due To Pesticide Exposure: In Silico Study","authors":"Sarmila Sarmila, Nafisah Nafisah, Hanna Habibah, Indah Saputri, Indah Setiawati, N. Komari","doi":"10.20527/jbk.v19i2.17415","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17415","url":null,"abstract":"Pesticide active ingredients have widespread toxicity effects on target and non-target organisms. Continuous exposure to pesticides causes cancer. Kelakai is thought to have potential cytotoxic activity against the growth of cancer cells. The aim of this research is to examine the potential activity of chemical compounds on Anaplastic Lymphoma Kinase (ALK) proteins exposed to organophosphate pesticides in silico. Protein and ligand preparation with the Chimera program, Docking using SwissDock, as well as virtual screening using the pkCSM web and ProTox. Ethion and neophytadiene have the most negative ∆G values of -8.62 kcal/mol and -8.39 kcal/mol, respectively. The binding site for ethion and neophytadiene compounds with the ALK protein is right at the active site of the ALK protein. Ethion is the most toxic organophosphate pesticide and has the potential to be cytogenic. Neophytadiene from kelakai compounds has the potential to act as a competitor in inhibiting the ALK protein. The similarity in the type and number of binding residues in ethion and neophytadiene in the ALK protein indicates competition between ethion and neophytadiene.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Of Gestational Age And Birth Weight With Neonatal Sepsis In Ulin Hospital Banjarmasin 班贾马辛乌林医院妊娠年龄和出生体重与新生儿败血症的关系

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17385

Pudji Andayani, Monica Anggriana Salim, P. G. Halim, A. Yunanto

{"title":"Association Of Gestational Age And Birth Weight With Neonatal Sepsis In Ulin Hospital Banjarmasin","authors":"Pudji Andayani, Monica Anggriana Salim, P. G. Halim, A. Yunanto","doi":"10.20527/jbk.v19i2.17385","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17385","url":null,"abstract":"Indonesia is ranked 7th in the country with the highest neonatal mortality rate in the world, respectively 60.000 neonatal deaths per year. Neonatal sepsis in one of the major causes of neonatal death. The aim of this study is to find the association of gestational age and birth weight with the incidence of neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021. This study is a retrospective study with a cross sectional approach at Neonatal Ward, Ulin Hospital Banjarmasin, South Borneo, January to December 2021. The total sample was 200 infants consisting of 100 healthy infants and 100 sepsis infants. The source of gestational age, birth weight, and diagnosis data were taken through patient medical records. The mean gestational age of healthy infant group was 38,45 weeks (all infants were at term) while in septic infant group was 33,59 weeks (70%preterm, 28%at-term, and 2%post-term). The average birth weight of healthy infant group was 3021.24 grams (all infants were normal birth weight) while in septic infant group was 2003,59 grams (25%normal birth weight, 40%low birth weight, 25%very low birth weight, and 10%extremely low birth weight). There were an association of gestational age and birth weight with neonatal sepsis, confidential rate was 95%. (p<0,000 and p<0,000). There were an association of gestational age and birth weight with neonatal sepsis in Ulin Hospital Banjarmasin, January-December 2021.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Home Sanitation and Clean Water Facilities in Stunting Cases at the Lampihong Health Center Area, Balangan 巴兰甘 Lampihong 健康中心地区发育迟缓病例的家庭卫生和洁净水设施

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17421

Farida Heriyani, Ainun Farida, Maria Ulfah

{"title":"Home Sanitation and Clean Water Facilities in Stunting Cases at the Lampihong Health Center Area, Balangan","authors":"Farida Heriyani, Ainun Farida, Maria Ulfah","doi":"10.20527/jbk.v19i2.17421","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17421","url":null,"abstract":"Stunting is a condition of growth failure in children under five years old (toddlers) due to chronic malnutrition and recurrent infections, especially in the first 1,000 days of life. One of the indirect causes is the availability of clean water and poor sanitation. Lampihong Community Health Center Balangan Regency is one of the areas with the highest stunting cases in South Kalimantan. This study aims to analyze the relationship between home sanitation and clean water facilities with the incidence of stunting in the Lampihong Community Health Center, Balangan Regency. The research method is analytic observational with a case control approach. The research sample consisted of 30 mothers of stunted toddlers as the case group and 30 mothers of non-stunted toddlers as the control group. Data analysis used the chi square test at a 95% confidence level. The research results showed that the majority of stunted toddlers lived in houses with unhealthy water closet, wastewater disposal and waste management that did not meet the requirements. Most of the stunted and non-stunted toddlers use clean water that meets the requirements. The results show that there is a significant relationship between home sanitation that does not meet the requirements and the incidence of stunting in toddlers, but there is no significant relationship between clean water facilities and the incidence of stunting in toddlers in the Lampihong Health Center, Balangan Regency.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Ramania Leaves (Bouea macrophylla Griffith) from South Kalimantan as a Mosquito Larvae Biolarvicidal 南加里曼丹的拉曼尼亚叶（Bouea macrophylla Griffith）作为蚊子幼虫杀虫剂的功效

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17386

Saftia Aryzki, Dwi Rizki Febrianti

{"title":"Effectiveness of Ramania Leaves (Bouea macrophylla Griffith) from South Kalimantan as a Mosquito Larvae Biolarvicidal","authors":"Saftia Aryzki, Dwi Rizki Febrianti","doi":"10.20527/jbk.v19i2.17386","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17386","url":null,"abstract":"Indonesia itself as a tropical country has many plants that can be used as biolarvicides, one of which is the ramania plant (Bouea macrophylla Griffith). Ramania fruit epidermis contains secondary metabolites such as flavonoids, saponins, phenolic tannins, alcohol, steroids and terpenoids where these compounds have a larvicidal effect. The purpose of this study was to determine the activity of the ethanol extract of the epidermis of the ramania fruit as a biolarvicidal Mosquito larvae from the LC50 value. This research is a laboratory experimental research. The treatment concentrations used in this study were 25 ppm, 50 ppm, and 100 ppm. Temephos 1% was used as a positive control. Concentrations were then tested on 20 larvae instar III. The results of SPSS analysis with a significance of <0.05 showed that there was an effect of treatment on the number of larvae deaths, where the results of Tuckey analysis showed that concentrations of 50 ppm and 100 ppm and Temephos 1% showed differences. which means the number of deaths of test larvae. The results showed that the ethanol extract of ramania rind of ramania fruit (Bouea macrophylla Griffith) was effective as a biolarvicidal mosquito larvae. The results of probit analysis showed that the LC50 of ethanol extract of ramania rind against larvae was 20,844 ppm which is a low toxic group in aquatic environments.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Self Management Through Family E - Coaching on Decreased Blood Glucose Levels in Diabetes Mellitus Patients 通过家庭电子辅导进行自我管理对降低糖尿病患者血糖水平的影响

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17422

Tut Handayani, Indargairi Indargairi, Alamsyah Alamsyah

引用次数: 0

The Association between Coping Mechanisms and Depression in Patients with Chronic Kidney Disease Undergoing Hemodialysis at Dr. Moewardi Hospital Surakarta 苏腊卡尔塔 Moewardi 医生医院接受血液透析的慢性肾病患者的应对机制与抑郁之间的关系

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17388

Wim Zweiryadinda, Tri Oktaviyantini, Wijaya Kusuma

引用次数: 0

The Risk of Adverse Drug-Drug Interactions for Stable Angina Pectoris Patients with Heart Failure Complication Prescribed Polypharmacy 心力衰竭并发稳定型心绞痛患者服用多种药物后发生药物间不良相互作用的风险

Berkala Kedokteran Pub Date : 2023-09-13 DOI: 10.20527/jbk.v19i2.17404

Ahmad Aldi Fadillah, Mohammad Bakhriansyah, Intan Yustikasari, P. W. Nurikhwan, D. L. Adiputro

{"title":"The Risk of Adverse Drug-Drug Interactions for Stable Angina Pectoris Patients with Heart Failure Complication Prescribed Polypharmacy","authors":"Ahmad Aldi Fadillah, Mohammad Bakhriansyah, Intan Yustikasari, P. W. Nurikhwan, D. L. Adiputro","doi":"10.20527/jbk.v19i2.17404","DOIUrl":"https://doi.org/10.20527/jbk.v19i2.17404","url":null,"abstract":"Stable angina pectoris (SAP) is an imbalance that occurs when myocardial oxygen need increases disproportionally, causing complaints of chest pain. Uncontrolled SAP can lead to a complication of heart failure (HF). Polypharmacy treatment frequently given to SAP patients with HF complications can be potentially detrimental for them. This study aims to determine the risk of adverse drug-drug interactions in SAP patients with HF complications prescribed polypharmacy. This was an analytic observational study with a cross-sectional approach using retrospective data from medical record data from 2020-2021 among hospitalized patients in cardiology ward Ulin General Hospital, Banjarmasin. Potential drug-drug interactions were determined using the Lexicomp tool from the UpToDate® site. Prevalence Odds Ratio (POR) and 95% Confidence Interval (95%CI) were determined using the Logistic Regression test at the 95% level of confidence. Twenty-four SAP patients with HF were recruited. According to its potential interactions, the most interactions were under category C (82.6%), followed by category B (11.3%) and category D (6.0%). Based on its level of severity, the most common was moderate (77.4%), followed by minor (13.0%) and major (9.5%). SAP patients with HF who were not prescribed polypharmacy had a lower risk of adverse drug-drug interactions by 64.7% compared to polypharmacy users, although it was not statistically difference (crude POR 0.353, 95% CI; 0.360-3.421; p-value = 0.369). This study shows that there is a tendency of lower risk of adverse drug-drug interactions in SAP patients with HF complication prescribed polypharmacy compared to those without polypharmacy, but the association is not statistically significant.","PeriodicalId":53378,"journal":{"name":"Berkala Kedokteran","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139340414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0