A. Bhattacharjee, Afm Anwar Hossain, S. Yeasmin, T. Akter
{"title":"Incidence, Epidemiology and Clinico-Pathological Status of Different Molecular Subtypes of Breast Cancer in NICRH, Dhaka","authors":"A. Bhattacharjee, Afm Anwar Hossain, S. Yeasmin, T. Akter","doi":"10.3329/DMCJ.V6I1.35962","DOIUrl":"https://doi.org/10.3329/DMCJ.V6I1.35962","url":null,"abstract":"Background: Molecular subtype determination of breast carcinoma is still an enigma in our perspective. We are far behind the genetic analysis but immunohistochemistry is commonly ensured now a days.Objective: To observe the incidence, epidemiological and clinico-pathological status of different molecular subtypes of breast cancer patients.Materials and method: At first 141 patients were enrolled by purposive sampling. Among them 138 patients were finalized according to the eligibility criteria. A pre-structured, peer reviewed, properly tested, interview and observation based data collection sheet was prepared. Data regarding epidemiological profile, clinical profile and histopathological profile were collected, compiled, edited and analyzed. Mean, frequency, chi-square test were adopted for analysis. Statistics were found significant at 5cm sized tumour in maximum diameter. Among the five major molecular subtypes both luminal A and triple negative breast cancer (TNBC) showed high prevalence (27.53%). Association of molecular subtypes with histopathological grading revealed TNBC was the most aggressive among all molecular subtypes. Axillary lymphadenopathy was present in almost all cases.Conclusion: Luminal A and TNBC were positive in most of the cases whereas TNBC showed higher association with advance histopathological grade. Clinical status was almost similar in all subtypes.Delta Med Col J. Jan 2018 6(1): 9-17","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"6 1","pages":"9-17"},"PeriodicalIF":0.0,"publicationDate":"2018-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V6I1.35962","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46299668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Structured Training to the Patients of Chronic Obstructive Pulmonary Disease Reduces Frequency of Hospital Readmission","authors":"Mizanur Rahman, M. Azhar, A. Saha, K. Nahar","doi":"10.3329/DMCJ.V6I1.35966","DOIUrl":"https://doi.org/10.3329/DMCJ.V6I1.35966","url":null,"abstract":"Background: Patient education after treatment of acute exacerbation in patients with chronic obstructive pulmonary disease (COPD) prevents frequent hospital readmission and improve quality of life.Objectives: To observe the impact of providing structured training to patients of COPD on repeated hospital admission.Materials and method: This prospective comparative study was carried out in the inpatient department of Medicine and Pulmonology Unit, Sir Salimullah Medical College and Mitford Hospital, Dhaka, Bangladesh, from January 2010 to June 2011. A total of 144 admitted patients with COPD with an attack of acute exacerbation were included in this study without having any significant or chronic comorbidity. Of the 144 patients, 72 were randomly allocated for receiving structured training (cases; Group-A) and the rest 72 patients did not receive the training (controls; Group-B).Results: The pertinent demographic characteristics, smoking status, and knowledge about different aspects of COPD, and medications used during acute exacerbation of COPD before intervention were almost similar between the groups. Over 30% of the patients who received structured training needed no hospital admission, 58.3% needed only one and 11.1% needed 2 or more admissions, while the other group required two or more admissions during the same period (p 2 consultations with physicians was significantly higher in the former group (26.4% vs. 6.9%) (p = 0.002), indicating an increased awareness on the part of that group.Conclusion: Structured training to COPD patients significantly reduced hospitalization and hospital stay for an acute exacerbation in this study.Delta Med Col J. Jan 2018 6(1): 35-44","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"6 1","pages":"35-44"},"PeriodicalIF":0.0,"publicationDate":"2018-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V6I1.35966","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46321683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jakir Hossain Bhuiyan Masud, Moniruzzaman Khan, Jesmin
{"title":"Pattern of Drug Abuse among Street Children of Dhaka: Inhalants are the Most Popular Drug","authors":"Jakir Hossain Bhuiyan Masud, Moniruzzaman Khan, Jesmin","doi":"10.3329/DMCJ.V6I1.35965","DOIUrl":"https://doi.org/10.3329/DMCJ.V6I1.35965","url":null,"abstract":"Background: Number of street children has been rising in Dhaka, the capital of Bangladesh, in recent years and also the prevalence of substance abuse is increasing among these children. Objective: This research work focuses on understanding street children’s perception/attitudes towards substance abuse. Materials and method: For this study, an inquiry based, self-administrated questionnaire was generated and a survey was conducted by authorized, trained persons. A total of 80 participants were enrolled in this initial research work. Results: Studying respondents from two major areas of Dhaka, it came out that sniffing dendrite is the most popular adhesive/inhalant among children because of its easy availability. For these children, the initiation process of sniffing adhesives starts as a part of street culture introduced by peers (87.5%, n = 70), for getting accepted into social street gangs. Thus, these children started drug abuse as a mean of endurance along with a little pleasure/escapism, even for a while to survive within the harsh reality of street life. Data from this initial study were used to build a topological-model of present/oncoming consequences/threats of substance abuse with suggested routes of social/medical interventions. The most encouraging fact is that understanding the adverse consequences of drug abuse, most of these children wanted to quit drug abuse (70%, n = 56) and wished for a better life. Conclusion: It is believed that this model would help in implementing measures for systematic drug abuse cessation for long-term rehabilitation programmes for these children, ensuring every child’s right to have a secured, healthy life. Delta Med Col J. Jan 2018 6(1): 29-34","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"6 1","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2018-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V6I1.35965","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45894625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rohingya Crisis – Health issues","authors":"Rezwanur Rahman","doi":"10.3329/dmcj.v6i1.35960","DOIUrl":"https://doi.org/10.3329/dmcj.v6i1.35960","url":null,"abstract":"The Rohingya people are a stateless Muslim-minority group that has been persecuted by Myanmar for many years.1 Recently the Rohingya refugees fled Myanmar's northern Rakhine state after insurgents attacked security forces in late August last year, prompting a military crackdown that has since been described as ethnic cleansing.2 According to a recent report of International Organization for Migration (IOM) and UNICEF, an estimated 688,000 Rohingya have entered into Bangladesh from Myanmar since 25 August 2017, and the total Rohingya population in Cox’s Bazar is now over 900,000.3 The majority of these people are now living in pre-existing camps and settlements, settlement extensions, spontaneous settlements and amongst the host community in Cox’s Bazar District with increasing need of humanitarian assistance, including shelter, food, clean water, and sanitation.3,4 Around 1.2 million people, including both newly arrived Rohingyas and their host communities, are estimated to be in need of health assistance. Based on the public health situation analysis published on 10 October 2017, WHO has graded this crisis as a level 3 emergency, the highest possible rating.5","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"6 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/dmcj.v6i1.35960","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43938541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Akhter, N. Majid, Syed Salahuddin Ahmed, Kuazi Dil Afroz, Rezwanur Rahman, S. Ali
{"title":"Cardiac Myxomas: A Histodemographic Analysis","authors":"A. Akhter, N. Majid, Syed Salahuddin Ahmed, Kuazi Dil Afroz, Rezwanur Rahman, S. Ali","doi":"10.3329/DMCJ.V6I1.35961","DOIUrl":"https://doi.org/10.3329/DMCJ.V6I1.35961","url":null,"abstract":"Background: Cardiac myxoma is the most common benign cardiac tumour, accounting for more than half of all primary cardiac tumours. Most myxomas are sporadic and the cause is largely unknown. Familial variants with an autosomal dominant inheritance exist. It is localized generally in the left atrium and typically develops in females. Clinical manifestations can mimic cardiac conditions and depend on the natural behaviour of the tumour and its location within the heart, ranging from being completely asymptomatic to causing sudden death. Establishing an early diagnosis is essential, which is confirmed by histopathology. Objective: The aim was to find the relation between cardiac myxomas with age, sex and cardiac sites. Materials and method: This cross sectional study was done in the pathology department of Delta Hospital Limited, Dhaka, Bangladesh, during the period of January 2014 to July 2016. A total of 24 cases were studied irrespective of age, sex along with clinical diagnosis. Results: Among the study subjects females were predominant (70.83%) and highest frequency of cases occurred in between 41-50 years of age (41.67%). Commonest site was left atrium (83.33%). Conclusion: The present study revealed that cardiac myxoma occurs most commonly in the 5th decade with female predominance and the most common site is left atrium. Delta Med Col J. Jan 2018 6(1): 4-8","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"6 1","pages":"4-8"},"PeriodicalIF":0.0,"publicationDate":"2018-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V6I1.35961","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42752618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Raihan Uddin, A. Jabbar, Shafiqur Rahman, Maooz Khan
{"title":"Comparison of the LMA-ProSeal and LMA-Classic in Children","authors":"Raihan Uddin, A. Jabbar, Shafiqur Rahman, Maooz Khan","doi":"10.3329/DMCJ.V6I1.35963","DOIUrl":"https://doi.org/10.3329/DMCJ.V6I1.35963","url":null,"abstract":"Background: The LMA-ProSeal is a new laryngeal mask airway with a rear cuff and drainage tube that allows a higher seal pressure than the LMA-Classic for the same intra-cuff pressure and it permits drainage of gastric secretions and access to the alimentary tract. Objective: This study compared the LMA-ProSeal and LMA-Classic in children for ease of insertion, airway sealing pressure and maintenance of airway. Materials and method: This comparative study was done during the period of January 2015 to December 2015 in BIRDEM Hospital, Dhaka, Bangladesh. Forty ASA 1-2 children undergoing circumcision, herniotomy and orchiopexy were included. The patients were randomly assigned to size 2.5 LMA-ProSeal or 2.5 LMA-Classic groups for airway management. We assessed success rates at first attempt of insertion, airway sealing pressure, maintenance of airway and postoperative complications. Results: There was no statistical difference between two groups for the success rates at first attempt of insertion and maintenance of airway but sealing pressure was significantly high in the LMA-ProSeal group. Regarding postoperative complication like injury to lip-teeth-tongue, blood staining and cough or laryngospasm were also not significant. Conclusion: We concluded that ease of insertion, maintenance of airway and risk of injury are similar between the LMA-ProSeal and the LMA-Classic in children. Delta Med Col J. Jan 2018 6(1): 18-21","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"6 1","pages":"18-21"},"PeriodicalIF":0.0,"publicationDate":"2018-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V6I1.35963","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43729213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. K. Paul, A. Chowdhury, R. Lodi, Shayda Ali, M. A. Basunia, H. M. A. Rouf
{"title":"Surgical Management of Breast Cancer under Local Anaesthesia: A Surgeon's Perspective","authors":"T. K. Paul, A. Chowdhury, R. Lodi, Shayda Ali, M. A. Basunia, H. M. A. Rouf","doi":"10.3329/dmcj.v5i2.33343","DOIUrl":"https://doi.org/10.3329/dmcj.v5i2.33343","url":null,"abstract":"Background: Treatment of breast cancer without surgery may not be effective. But in elderly patients with lots of co-morbidities, surgical management often cannot be done due to the significant risks of general anesthesia. The need for a safe, easy and effective alternative anaesthetic technique that can provide adequate peroperative analgesia as well as reduced anxiety in such group of patients was the main indication for this study. Materials and method: This prospective study was done on eleven patients, with coexisting medical conditions and who were not at all fit for general anaesthesia, and underwent breast cancer surgery under local anaesthesia. The patients were studied with regard to intraoperative analgesia, haemodynamic stability and complications related to technique. The study was done in Delta Medical College Hospital, Dhaka, Bangladesh. Results: Mean±SD of study patients were 64.7±7 years old and all were suffering from coexisting medical conditions. Following local anaesthesia, mean intraoperative heart rate was 81.5±11.8 beats/min and the mean blood pressure was 127.3/79±9.6/7.0 mmHg. Patients felt no pain after infiltration of local anaesthetics, but experienced it if any place was missed before dissection. No complication occurred due to this procedure. All the candidates were fully satisfied with the procedure. Conclusion: Local anaesthesia provides satisfactory pain control along with keeping haemodynamics stable for surgical treatment of breast cancer among elderly patients having co-morbid conditions. Delta Med Col J. Jul 2017 5(2): 63-67","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"29 33","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41266470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Rahman, T. Chowdhury, Z. Nasreen, S. Shermin, N. Sultana, M. Nessa
{"title":"Clinical Study of Postmenopausal Bleeding","authors":"S. Rahman, T. Chowdhury, Z. Nasreen, S. Shermin, N. Sultana, M. Nessa","doi":"10.3329/DMCJ.V5I2.33346","DOIUrl":"https://doi.org/10.3329/DMCJ.V5I2.33346","url":null,"abstract":"Background: Women with postmenopausal bleeding (PMB) should be thoroughly evaluated. A thorough examination may help in the diagnosis of vulval, vaginal, cervical or pelvic pathology. Objective: This study was carried out to find the probable causes in patients presenting with postmenopausal bleeding. Materials and method: This observational study included 50 women with postmenopausal bleeding and was conducted in the department of Obstetrics and Gynaecology of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM) Hospital, Dhaka, Bangladesh, from January 2004 to December 2004. Transvaginal ultrasonogram (TVS), diagnostic curettage and cervical biopsy were done and histopathology report was collected. Results: The mean age of the patients was 57.74 years (range 48-75 years), and the median age of menopause was 50 years. Among the patients 18 (36%) had only diabetes and 25 (50%) patients had both diabetes and hypertension. Nineteen patients (38%) were overweight, 5 patients (10%) were obese and 2 (4%) were morbidly obese. Per speculum examination revealed suspected cervical carcinoma in 5 cases (10%) and cervical polyp in 1 case (2%). The most common clinical finding was atrophy of the uterus and vagina in 26 patients (52%). TVS revealed endometrial thickness of 5mm or more in 17 cases (37.7%) and < 5mm in 26 cases (57.7%). Nine patients (18%) had carcinoma, 16 patients (32%) had benign pathology and 19 (38%) patients had endometrial atrophy on histology. Conclusion: A detailed history taking, thorough physical examination and relevant investigations can lead to a correct detection of cause of postmenopausal bleeding. Those who have normal adnexae and thin endometrium (endometrium <5mm) may not need endometrial biopsy. Delta Med Col J. Jul 2017 5(2): 83-88","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"5 1","pages":"83-88"},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V5I2.33346","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44817918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case Report: Symptomatic Sacral Tarlov Cyst in a Male of 24 Years","authors":"Q. Ullah, M. Hussain, A. Sayed, M. Quader","doi":"10.3329/DMCJ.V5I2.33349","DOIUrl":"https://doi.org/10.3329/DMCJ.V5I2.33349","url":null,"abstract":"Perineural (Tarlov) cyst, a rare but benign condition, is meningeal dilatations of the posterior spinal nerve root sheath that most often affects sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging (MRI) and can often be demonstrated by computerized tomography (CT) to communicate with the spinal subarachnoid space. The cyst can enlarge via a net inflow of cerebrospinal fluid, eventually causing symptoms by distorting, compressing, or stretching adjacent nerve roots. It is generally agreed that asymptomatic Tarlov cysts do not require treatment. When symptomatic, the potential surgery-related benefit and the specific surgical intervention remain controversial. A 24 years old male presented with a history of trauma and pain in his low back with dull headache for six months. Physical and radiographic examination was consistent with tarlov cyst. Microsurgical excision with plication of the cyst wall was performed. Histo-pathological examination confirmed the diagnosis of Tarlov cyst. Excellent clinical and functional results were obtained with no recurrence after 6 months of follow-up. Tarlov cyst in a male of age 24 is a rare entity and decision making for management poses difficulties. Our experience with microsurgical excision with plication of the cyst wall was quite satisfactory with excellent clinical result, and we recommend this as one of the satisfactory modalities of treatment of Tarlov cyst in adult. Delta Med Col J. Jul 2017 5(2): 99-103","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"5 1","pages":"99-103"},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V5I2.33349","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48645685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction Notice for \"Age Estimation from Ossification of Clavicle: A Comprehensive Review\"","authors":"Md. Rezwanur Rahman","doi":"10.3329/DMCJ.V5I2.33401","DOIUrl":"https://doi.org/10.3329/DMCJ.V5I2.33401","url":null,"abstract":"On 17th May 2017 the Editorial Board of Delta Medical College Journal agreed to retract the article 'Age Estimation from Ossification of Clavicle: A Comprehensive Review' published in Delta Medical College Journal, Vol.4(2) pages 89-96 (DOI: http://dx.doi.org/10.3329/dmcj.v4i2.29381 ) as it was found to contain an extensive overlap of text sections from the following published article: 'Estimation of age from ossification of clavicle: A Comprehensive Review' published in the Journal of Indian Academy of Forensic Medicine, Vol.31(3) pages 277-284. http://medind.nic.in/jal/t09/i3/jalt09i3p277.pdf","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"5 1","pages":"105"},"PeriodicalIF":0.0,"publicationDate":"2017-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3329/DMCJ.V5I2.33401","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45504107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}