Cardiac Myxomas: A Histodemographic Analysis

A. Akhter, N. Majid, Syed Salahuddin Ahmed, Kuazi Dil Afroz, Rezwanur Rahman, S. Ali
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Abstract

Background: Cardiac myxoma is the most common benign cardiac tumour, accounting for more than half of all primary cardiac tumours. Most myxomas are sporadic and the cause is largely unknown. Familial variants with an autosomal dominant inheritance exist. It is localized generally in the left atrium and typically develops in females. Clinical manifestations can mimic cardiac conditions and depend on the natural behaviour of the tumour and its location within the heart, ranging from being completely asymptomatic to causing sudden death. Establishing an early diagnosis is essential, which is confirmed by histopathology. Objective: The aim was to find the relation between cardiac myxomas with age, sex and cardiac sites. Materials and method: This cross sectional study was done in the pathology department of Delta Hospital Limited, Dhaka, Bangladesh, during the period of January 2014 to July 2016. A total of 24 cases were studied irrespective of age, sex along with clinical diagnosis. Results: Among the study subjects females were predominant (70.83%) and highest frequency of cases occurred in between 41-50 years of age (41.67%). Commonest site was left atrium (83.33%). Conclusion: The present study revealed that cardiac myxoma occurs most commonly in the 5th decade with female predominance and the most common site is left atrium. Delta Med Col J. Jan 2018 6(1): 4-8
心脏黏液瘤:组织学分析
背景:心脏黏液瘤是最常见的良性心脏肿瘤,占所有原发性心脏肿瘤的一半以上。大多数黏液瘤是散发性的,其病因在很大程度上是未知的。存在常染色体显性遗传的家族变异。它通常局限于左心房,通常发生于女性。临床表现可以模仿心脏状况,并取决于肿瘤的自然行为及其在心脏中的位置,从完全无症状到导致猝死不等。建立早期诊断是必要的,这是由组织病理学证实。目的:探讨心脏黏液瘤与年龄、性别、心脏部位的关系。材料与方法:本横断面研究于2014年1月至2016年7月在孟加拉国达卡德尔塔医院有限公司病理科完成。共研究了24例病例,不考虑年龄、性别和临床诊断。结果:研究对象中以女性居多(70.83%),41 ~ 50岁年龄组发病率最高(41.67%)。最常见部位为左心房(83.33%)。结论:心脏黏液瘤多见于5 ~ 10岁,以女性为主,多发于左心房。中华医学杂志,2018,6(1):4-8
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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