Sabrina Rahman, Maha Harun, T. Dipta, Farida Parvin
{"title":"Glanzmann Thrombasthenia – A Rare Case Report","authors":"Sabrina Rahman, Maha Harun, T. Dipta, Farida Parvin","doi":"10.3329/dmcj.v9i2.74874","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74874","url":null,"abstract":"Glanzmann thrombasthenia is a rare inherited bleeding disorder resulting from mutation in platelet membrane glycoprotein (GP) IIb or IIIa leading to impaired platelet function which is characterized by defective platelet aggregation and diminished clot retraction. Glanzmann thrombasthenia patients commonly visit to physician with features of bleeding. Here we discuss about the case of a 32-years-old young female presented with menorrhagia, ecchymosis and occasional gum bleeding. Her coagulation profile was in favor of Glanzmann thrombasthenia. This rare disease has a good outcome if early diagnosis and proper management can be ensured. \u0000Delta Med Col J. Jan 2021;9(2): 101-103 ","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"56 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Efficacy of Seed Extract of Tamarindus indica and Vitamin E on the Liver Weight of Long Evan’s Rats Intoxicated with Paracetamol","authors":"Nasrin Jahan Shammi, Md Ismail Khan, Zubaida Khatoon Choudhury, Muazzem Hossain, Nashid Sultana, Mst Nadira Parvin, Md Mojib Uddin","doi":"10.3329/dmcj.v9i2.74870","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74870","url":null,"abstract":"Background: Tamarindus indica is an antioxidant rich plant. It has therapeutic interest in drugs and xenobiotics induced liver damage.\u0000Objective: This study was aimed to explore the effectiveness of ethanolic extract of seed of Tamarindus indica on liver weight when liver is intoxicated with paracetamol and to compare it with the effects of Vitamin E, a known hepatoprotectant. Materials and method: A total of twenty four Long Evan’s rats were collected and divided into four groups. Each group having sixrats (n=6). Control group received normal diet ad libitum, only paracetamol group received paracetamol (1500 mg/kg) for 12 days and rest two groups received paracetamol (1500 mg/kg) along with ethanolic extract of seed of Tamarindus indica (1250 mg/kg) and vitamin E (500 mg/kg) for 12 days respectively. On 13th day, all rats were sacrificed. Then livers were collected and weighed by an electronic balance.\u0000Results: In this study, the mean (±SD) liver weight was 4.08±0.23 in control group, 6.27±0.68 in only paracetamol treated group, 5.22±0.72 and 4.57±0.86 in paracetamol along with seed extract of Tamarindus indica and vitamin E treated group respectively.\u0000Conclusion: The present study showed that mean (±SD) weight of liver increased with paracetamol and decreased with seed extract of Tamarindus indica which is similar to the effects of vitamin E. \u0000Delta Med Col J. Jan 2021;9(2): 80-83","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"46 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
-. Maherunnessa, S. Shermin, Shahnaz Rahman, N. Naher, Mehbuba Jahan
{"title":"The Role of Transvaginal Ultrasonography in the Evaluation of Postmenopausal Bleeding","authors":"-. Maherunnessa, S. Shermin, Shahnaz Rahman, N. Naher, Mehbuba Jahan","doi":"10.3329/dmcj.v9i2.74872","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74872","url":null,"abstract":"Background: Endometrial cancer is currently the most common malignancy of the female genital tract. Most of the women with endometrial cancer initially present with postmenopausal bleeding (PMB) and may be assessed initially with either endometrial biopsy or transvaginal ultrasonography.\u0000Objective: The objective of this study was to evaluate transvaginal ultrasound (TVS) measurement of endometrial thickness (ET) in diagnosing endometrial cancer in women with postmenopausal bleeding.\u0000Materials and method: This was a prospective study. Transvaginal ultrasonography and Papanicolaou smear were performed in 291 women presenting with postmenopausal bleeding aged >50 years and were followed up for one year in BIRDEM General Hospital from September 2017 to August 2018.\u0000Results: One hundred and seventeen women had an endometrial thickness ≤4 mm and one endometrial cancer (0.85%) was diagnosed in this group. Endometrial biopsy was performed in women who had recurrent bleeding. But in women with an endometrial thickness of ≥5mm (174 out of 291 women), endometrial cancer was diagnosed in 9.77%, atypical hyperplasia in 5.17%, ovarian malignancy in 1.72% and total malignancy was 17.8%.\u0000Conclusion: Transvaginal ultrasonography using a ≤4 mm cut-off has high sensitivity for detecting endometrial cancer and can identify women with PMB who are highly unlikely to have endometrial cancer, thereby avoiding more invasive endometrial biopsy.\u0000Delta Med Col J. Jan 2021;9(2): 91-95 ","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"3 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Motahar Hossain, M. Flora, Md Saydur Rahman, Md Nurul Amin, Murshida Mosharref, F. Zafreen
{"title":"Treatment Related Factors Associated with Non-adherence to Anti-Tuberculosis Treatment","authors":"Md Motahar Hossain, M. Flora, Md Saydur Rahman, Md Nurul Amin, Murshida Mosharref, F. Zafreen","doi":"10.3329/dmcj.v9i2.74873","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74873","url":null,"abstract":"Background: Non-adherence to anti-tuberculosis treatment may result in persistent infectiousness on the part of the patient and a higher rate of treatment failure, relapse and drug resistance and therefore, is a significant barrier to the success in tuberculosis control.\u0000Objective: To determine the treatment related factors associated with non-adherence to anti-tuberculosis treatment among tuberculosis patients. Materials and method: This case control study was carried out among purposively selected 47tuberculosis patients non-adherent to treatment (cases) and 94 tuberculosis patients adherent to treatment (controls) and were interviewed with a semi-structured questionnaire and checklist in selected DOTS centres of Dhaka city.\u0000Results: Statistical analysis shows that, factors like delay in seeking tuberculosis treatment for >6 weeks (OR=4.57; 95% CI, 1.48-14.1) and getting medicine weekly once (OR=2.8; 95% CI, 1.13-6.77) were more likely to be associated with non-adherence to treatment. Lessfrequent visit by health providers (p=0.02), no support for side effect (p=0.042) and non-observation of medication (p=0.009) were also found significant. The reasons behind missing anti-TB doses among non-adherent cases were due to feeling better (53.2%), personal reason (25.5%), feeling worse (19.1%) and forgot to take medicine (2.2%).\u0000Conclusion: Mass awareness among the tuberculosis patients is required to improve attitude towards anti-tuberculosis treatment and activities of tuberculosis control programme require further strengthening especially in targeting the patients of low economic status.\u0000Delta Med Col J. Jan 2021;9(2): 96-100 ","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"55 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Autism Spectrum Disorder (ASD)","authors":"Ruma Sen Gupta","doi":"10.3329/dmcj.v9i2.74864","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74864","url":null,"abstract":"Abstract not available\u0000Delta Med Col J. Jan 2021;9(2): 63-64","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"41 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehjabeen Tasnuva Aslam, Sadia Islam, S. B. Kalam, Dr. Mehjabeen Tasnuva
{"title":"Clinical Presentation and Outcome of Patients Presented with Acute Confusional State (ACS) in a Tertiary Care Hospital of Bangladesh","authors":"Mehjabeen Tasnuva Aslam, Sadia Islam, S. B. Kalam, Dr. Mehjabeen Tasnuva","doi":"10.3329/dmcj.v9i2.74869","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74869","url":null,"abstract":"Background: Acute confusional state (ACS) or delirium is a clinical condition categorized by troubled consciousness, cognitive function, or perception. The key to the management of cases of ACS lies in recognizing a cause or other contributing illness and alleviating it.\u0000Objective: To evaluate the patients of ACS intending to identify the clinical presentation of the ACS along with the outcome evaluation of its prognostic importance.\u0000Materials and method: A total of 50 patients of ACS fulfilling the DSM-4 criteria were enrolled purposively. It was a hospital-based cross-sectional type of observational study conducted among adult patients of more than 18 years of age for nine months period in the medicine department of Dhaka Medical College Hospital.\u0000Results: The mean age of patients was 63.18±9.8 years. Majority of the patients (66%) were male. Hypertension was the most common (46%) associated condition followed by obesity (22%). Fever was common in the majority of cases (78%) followed by disorientation (64%). Among the patients with cerebrovascular accidents, 70.59% had multiple infarcts and 29.42% showed hemorrhage in CT scans of the brain. Most of the patient's (76%) recovery was without any sequelae. Only 6% of patients died during the hospital stay.\u0000Conclusion: Acute confusional state (ACS) is among the most common problems in general medicine. Hence, treatment and further workup should run parallel to avoid the morbidity and mortality related to these circumstances. \u0000Delta Med Col J. Jan 2021;9(2): 75-79","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"46 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benefits and Challenges of Online Teaching Learning from the Students’ View","authors":"Rayhana Sultana, Rono Mollika, Afroza Khanam Sumy, S. Shahjamal, Farzana Alam, Pran Ashraf","doi":"10.3329/dmcj.v9i2.74868","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74868","url":null,"abstract":"Background: Online learning is the major concept in education which converts the traditional educational shape into a new form that transforms in person or physical learning into a virtual approach of learning. It is an alternative to traditional classroom learning and involves using primarily the internet and one or more other technologies.\u0000Objective: This study explores the perception of students regarding its benefits and challenges and recommendations.\u0000Materials and method: Data were collected from 273 students of 1st and 2nd year MBBS from January 2021 to February 2021 at Enam Medical College, Savar, Dhaka, Bangladesh, using a predesigned validated questionnaire.\u0000Results: The findings of the present study revealed that most of the students lack in academic or institutional knowledge regarding the ICT tools used in online learning process. The benefits included its flexibility regarding the time and place, sharing of information is easy and cost effective and allows mass audiences. Whereas, less effective in practice-based learning, instant feedback is difficult, lack of attentiveness, disturbance of physical health and diminished social interaction were identified as major disadvantages\u0000Conclusion: Online learning has its own set of advantages and disadvantages as other teaching methods. The purpose of this study was to assess the current state of online learning activities from the students’ perspective. \u0000Delta Med Col J. Jan 2021;9(2): 69-74","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"51 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shayda Ali, Fouzia Sultana, Russel Ahmed Khan Lodi, Tapesh Kumar Paul, Khaleda Nazneen Bari
{"title":"Role of Adding Topical Metronidazole in the Treatment of Acute Anal Fissure","authors":"Shayda Ali, Fouzia Sultana, Russel Ahmed Khan Lodi, Tapesh Kumar Paul, Khaleda Nazneen Bari","doi":"10.3329/dmcj.v9i2.74871","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74871","url":null,"abstract":"Background: An anal fissure is a longitudinal ulcer in the anoderm of the distal anal canal which extends from the anal verge proximally towards, but not beyond, the dentate line. Anal fissure is a disease characterized by severe pain in the anorectal region with constipation, per rectal bleeding and sometime itching. Recently, anaerobic bacteria are sorted out as a causative factor.\u0000Objective: This study investigates patient compliance in the treatment of anal fissure with adding topical metronidazole. Materials and method: A total number of 100 patients attended to the General Surgery Clinic of Delta Medical College Hospital, Department of Surgery, between December 2020 and May 2021 and diagnosed with acute anal fissure were included in this prospective study. Patients older than 18 years, including non-pregnant, pregnant and lactating women are recruited. Patients were randomly divided in two groups. One group (group: 1) was treated with topical glyceryl trinitrate [0.4% nitroglycerin ointment], and the other group (group: 2) was treated with topical glyceryl trinitrate [0.4% nitroglycerin ointment] and topical antibiotic [metronidazole 0.75%].\u0000Results: There is no difference between the groups regarding age and symptoms. From week 1, fissure healing rates were high in group 2. Group 2 VAS score levels were lower than group 1 and achieved by group 1 only in week 4. Compliance of pregnant and lactating lady was more in group 2.\u0000Conclusion: Adding topical metronidazole to treatment of acute anal fissure reduces the duration and severity of pain, shortens healing time and increases the healing rate. \u0000Delta Med Col J. Jan 2021;9(2): 84-90","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"5 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141649628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Razia Sultana, Selina Ahmed, Nasima Sultana, F. Diba
{"title":"ALT in Preeclampsia","authors":"Razia Sultana, Selina Ahmed, Nasima Sultana, F. Diba","doi":"10.3329/dmcj.v9i2.74867","DOIUrl":"https://doi.org/10.3329/dmcj.v9i2.74867","url":null,"abstract":"Background: Preeclampsia is the most frequent cause of abnormal liver function test in pregnancy. Women with preeclampsia and raised serum alanine aminotransferase (ALT) have chance of greater proteinuria and more maternal complications than those with normal liver function.\u0000Objective: The present study was designed to assess the association of serum ALT with preeclampsia. Materials and method: A case control study was conducted in the Department of Biochemistry, Dhaka Medical College,Dhaka, Bangladesh, from July 2010 to June 2011. From the pregnant women in third trimester of pregnancy attending in Obstetrics and Gynecology Department of Dhaka Medical College Hospital, 50 diagnosed cases of preeclampsia were selected purposively as cases and 50 normal healthy pregnant women as controls. Serum ALT concentration was measured in all the study subjects.\u0000Results: The mean serum ALT concentration in cases and controls were 57.92±20.99 U/L and 15.46±2.66 U/L respectively. The level was significantly higher in cases than that of controls (p=0.001).\u0000Conclusion: The study revealed that increased serum ALT concentration is associated with preeclampsia. \u0000Delta Med Col J. Jan 2021;9(2): 65-68","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"26 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141650500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Syed Mohammad Shaifuddin, Md Abdul Wahab, F. Zafreen, Jaida Jalal Sarker
{"title":"Clinicopathologic Features and Outcome of COVID-19 Patients Attended at a Secondary Hospital in Bangladesh during the Pandemic","authors":"Syed Mohammad Shaifuddin, Md Abdul Wahab, F. Zafreen, Jaida Jalal Sarker","doi":"10.3329/dmcj.v9i1.71330","DOIUrl":"https://doi.org/10.3329/dmcj.v9i1.71330","url":null,"abstract":"Background: Coronavirus Disease 2019 (COVID-19) is an acute respiratory diseasethat can present varieties of clinical and pathologic manifestation. Sometimes it presentwith severe manifestation which ultimately lead to respiratory failure and death.COVID-19 patients with other comorbidities may develop a life-threatening situation.Objective: To describe the clinicopathologic features and outcome of COVID-19patients admitted in Combined Military Hospital (CMH) Rangpur, Bangladesh.Materials and method: This cross-sectional study was conducted at CMH Rangpur,Bangladesh, from 1 May 2021 to 30 August 2021 among purposively selected 416 casesof COVID-19 positive patients. Data were collected from the medical records of thehospital admitted patients in a structured case report form. Results: Highest numbers ofthe respondents were in the age group of 31-50 years (49.03%) with male predominance(72.28%). About 89% were Muslim and 54.81% were educated up to higher secondarylevel. Fever (90.86%) was the common presenting symptoms followed by cough(73.55%), sore throat (30.28%). About 24.51%, 23.07%, 11.05% had hypertension,diabetes mellitus and respiratory comorbidities respectively. Lymphopenia (75.24%)and elevated C-Reactive Protein (54.08%) were observed in most of the cases. Only8.17% patients had critical illness that needed intensive care unit admission. Majority(91.82%) fully recovered from the illness while 1.92% expired. Conclusions: The mostcommonly reported symptom was fever (90.86%) among all the COVID-19 positivepatients. Majority (62.25%) of the patients belonged to mild cases. Overall mortalitywas 1.92%. In most cases the clinical presentation is that of a respiratory infection withsymptom severity ranging from a mild influenza like illness. \u0000Delta Med Col J. Jan 2021;9(1):3-8","PeriodicalId":53280,"journal":{"name":"Delta Medical College Journal","volume":"48 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139797634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}