Sabrina Rahman, Maha Harun, T. Dipta, Farida Parvin
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引用次数: 0
摘要
格兰兹曼血栓形成症是一种罕见的遗传性出血性疾病,是由于血小板膜糖蛋白(GP)IIb或IIIa发生突变,导致血小板功能受损,其特点是血小板聚集功能缺陷和血块回缩功能减弱。格兰兹曼血栓形成症患者通常以出血为特征就诊。本文讨论的病例是一名 32 岁的年轻女性,表现为月经过多、瘀斑和偶尔牙龈出血。她的凝血功能检查结果显示她患有格兰兹曼血栓形成症。如果能确保早期诊断和适当治疗,这种罕见疾病的预后会很好。 Delta Med Col J. Jan 2021;9(2):101-103
Glanzmann thrombasthenia is a rare inherited bleeding disorder resulting from mutation in platelet membrane glycoprotein (GP) IIb or IIIa leading to impaired platelet function which is characterized by defective platelet aggregation and diminished clot retraction. Glanzmann thrombasthenia patients commonly visit to physician with features of bleeding. Here we discuss about the case of a 32-years-old young female presented with menorrhagia, ecchymosis and occasional gum bleeding. Her coagulation profile was in favor of Glanzmann thrombasthenia. This rare disease has a good outcome if early diagnosis and proper management can be ensured.
Delta Med Col J. Jan 2021;9(2): 101-103