{"title":"Immediate Repair for Laceration of the Tunica Albuginea of the Corpora Cavernosa and Penile Urethral Injury Caused by Blunt Trauma to the Flaccid Penis: A Case Report","authors":"Rikushi Fujimura, Yoshiyuki Ishiura, Daimon Kurauchi, Takafumi Shimada, Renato Naito, Hiroaki Iwamoto, Susumu Niikura, Atsushi Mizokami","doi":"10.1002/iju5.70173","DOIUrl":"10.1002/iju5.70173","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Blunt trauma to the flaccid penis rarely causes laceration of the tunica albuginea of the corpora cavernosa.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 31-year-old male patient sustained blunt trauma to the flaccid penis during a basketball game, causing subcutaneous hematoma, hematuria, and urinary retention. Computed tomography demonstrated a laceration of the tunica albuginea of the corpora cavernosa. Immediate surgical exploration confirmed the laceration of the tunica albuginea and the partial disruption of the penile urethra. Both injuries were repaired, and a suprapubic catheter was inserted. On postoperative day 12, retrograde urethrography revealed no leakage; however, on postoperative day 24, leakage was observed at the injury site. The suprapubic catheter was maintained for 3 months. Final imaging confirmed urethral patency without leakage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>We report a rare case of blunt trauma to the flaccid penis. Immediate repair was successful, and the patient recovered without stricture, although a compressive mechanism caused delayed urethral leakage.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13051913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adult-Onset Effmann Type IIA2 Y-Type Urethral Duplication Presenting as Unexplained Perineal Wetness: A Case Report Highlighting Diagnostic Pitfalls and Tailored Surgical Management","authors":"Norichika Ueda, Tadahiko Kimura, Kentaro Takezawa, Taigo Kato, Koji Hatano, Yoichi Kakuta, Norio Nonomura, Atsunari Kawashima","doi":"10.1002/iju5.70174","DOIUrl":"10.1002/iju5.70174","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Persistent perineal wetness in adults with normal standard imaging is uncommon and may indicate rare congenital anomalies such as urethral duplication.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A man in his early 20s presented with a 3-year history of intermittent perineal wetness of unknown origin. Extensive gastrointestinal and urological investigations were unrevealing. Indigo carmine administration confirmed urinary leakage, prompting focused evaluation. Endoscopic assessment with meticulous perineal inspection under general anesthesia identified a tiny, non-inflamed perineal opening. Fistulography and cystoscopy demonstrated an accessory tract arising from the prostatic urethra and opening to the perineum, consistent with Effmann type IIA2 Y-type urethral duplication, extremely rare in adult-onset. Complete excision was achieved using a combined perineal and laparoscopic transabdominal approach with light-emitting catheter guidance, preserving urinary continence and erectile function. Symptoms resolved immediately without recurrence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlighted key diagnostic pitfalls and demonstrates effective surgical management of adult-onset type IIA2 Y-type urethral duplication.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13052196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IJU Case ReportsPub Date : 2026-03-26eCollection Date: 2026-03-01DOI: 10.1002/iju5.70167
{"title":"Correction to \"Successful Treatment of Paranasal Sinus Metastasis From Renal Cell Carcinoma With Immune Checkpoint Inhibitors and Radiotherapy: A Case Report\".","authors":"","doi":"10.1002/iju5.70167","DOIUrl":"https://doi.org/10.1002/iju5.70167","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1002/iju5.70156.].</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70167"},"PeriodicalIF":0.0,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IJU Case ReportsPub Date : 2026-03-19eCollection Date: 2026-03-01DOI: 10.1002/iju5.70171
Tsubasa Kondo, Toshifumi Tsurusaki, Akihiro Asai, Lisa Komuro, Kuniko Abe
{"title":"First Report of Laparoscopic Radical Nephroureterectomy Following Extraperitoneal Tubeless Umbilical Cutaneous Ureterostomy.","authors":"Tsubasa Kondo, Toshifumi Tsurusaki, Akihiro Asai, Lisa Komuro, Kuniko Abe","doi":"10.1002/iju5.70171","DOIUrl":"https://doi.org/10.1002/iju5.70171","url":null,"abstract":"<p><strong>Introduction: </strong>Extraperitoneal tubeless umbilical cutaneous ureterostomy is a useful urinary diversion technique for patients with shortened ureters or high risk of upper urinary tract recurrence. However, radical nephroureterectomy following this diversion has not been previously reported.</p><p><strong>Case presentation: </strong>A 67-year-old man underwent radical cystoprostatourethrectomy with extraperitoneal tubeless umbilical cutaneous ureterostomy for high-risk urothelial carcinoma with bilateral ureteral shortening. Twenty-four months later, left-sided upper tract urothelial carcinoma was diagnosed, and laparoscopic left radical nephroureterectomy was performed. Although dense adhesions necessitated partial small-bowel resection, complete nephroureterectomy was achieved without major complications.</p><p><strong>Conclusion: </strong>To the best of our knowledge, this is the first report of radical nephroureterectomy performed after umbilical cutaneous ureterostomy. This urinary diversion may represent a reasonable option for selected patients at high risk of upper urinary tract recurrence.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70171"},"PeriodicalIF":0.0,"publicationDate":"2026-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Durable Disease Control With Nivolumab in Malignant Epithelioid Angiomyolipoma: A Case Report.","authors":"Hiroki Shimoda, Shohei Fukuda, Daiki Yafuso, Kouhei Yamamoto, Yudai Ishikawa, Hiroshi Fukushima, Yuma Waseda, Hajime Tanaka, Soichiro Yoshida, Yasuhisa Fujii","doi":"10.1002/iju5.70170","DOIUrl":"https://doi.org/10.1002/iju5.70170","url":null,"abstract":"<p><strong>Introduction: </strong>Epithelioid angiomyolipoma is a subtype of perivascular epithelioid cell tumors that may exhibit malignant behavior. While mammalian target of rapamycin inhibitors are commonly used for systemic treatment, the efficacy of immune checkpoint inhibitors remains unclear.</p><p><strong>Case presentation: </strong>A 58-year-old man was diagnosed with epithelioid angiomyolipoma after partial nephrectomy of a right renal mass. The tumor recurred locally, and multiple lung metastases developed despite surgical resection. Nivolumab was initiated after disease progression on everolimus, resulting in durable disease control for over 3 years. Immunohistochemistry revealed high PD-L1 expression and CD8+ T-cell infiltration within the primary tumor.</p><p><strong>Conclusion: </strong>Immune checkpoint inhibitors may be effective treatment options for malignant epithelioid angiomyolipoma with PD-L1 expression and CD8+ T-cell infiltration.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70170"},"PeriodicalIF":0.0,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IJU Case ReportsPub Date : 2026-03-16eCollection Date: 2026-03-01DOI: 10.1002/iju5.70169
Kento Morozumi
{"title":"Editorial Comments on PTHrP-Producing Renal Cell Carcinoma Presenting as Rapidly Progressive Cognitive Impairment: A Case Report.","authors":"Kento Morozumi","doi":"10.1002/iju5.70169","DOIUrl":"https://doi.org/10.1002/iju5.70169","url":null,"abstract":"","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70169"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IJU Case ReportsPub Date : 2026-03-16eCollection Date: 2026-03-01DOI: 10.1002/iju5.70166
Fumihiro Ito, Koki Kobayashi, Gaku Hayashi, Shunsuke Kamijo, Takashi Fujita
{"title":"Delayed Clinical Manifestation of Malignant Potential in a Cortisol-Secreting Adrenal Tumor Initially Diagnosed as Adenoma.","authors":"Fumihiro Ito, Koki Kobayashi, Gaku Hayashi, Shunsuke Kamijo, Takashi Fujita","doi":"10.1002/iju5.70166","DOIUrl":"https://doi.org/10.1002/iju5.70166","url":null,"abstract":"<p><strong>Introduction: </strong>Distinguishing adrenocortical carcinoma (ACC) from adenoma is often difficult, particularly in hormonally active tumors with borderline histologic features.</p><p><strong>Case presentation: </strong>A 55-year-old woman presented with abdominal distension and central obesity. Hormonal evaluation confirmed ACTH-independent Cushing's syndrome. Imaging revealed a 60-mm left adrenal mass. Laparoscopic adrenalectomy was performed; pathology was initially interpreted as cortical adenoma with mild nuclear atypia and a Ki-67 labeling index of 6%. The patient remained disease-free until year three postoperatively when rising cortisol levels and surveillance imaging revealed a 36-mm retroperitoneal mass. Open nephrectomy and tumor excision were performed. Histopathology confirmed ACC. Retrospective review of the initial specimen revealed features consistent with early carcinoma.</p><p><strong>Conclusion: </strong>This case illustrates that cortisol-producing adrenal tumors initially diagnosed as adenomas may harbor unrecognized malignant potential, which can become clinically evident several years after surgery.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70166"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Emergency Cardiac Surgery for Intraoperative Pulmonary Artery Tumor Embolism During Renal Cell Carcinoma Surgery: A Case Report.","authors":"Toshiki Kijima, Akihiko Nagoshi, Kento Kobayashi, Ryo Nagaoka, Yuya Sato, Takashi Kato, Shinsuke Hamagchi, Shigeki Yamaguchi, Hirotsugu Fukuda, Takao Kamai","doi":"10.1002/iju5.70168","DOIUrl":"https://doi.org/10.1002/iju5.70168","url":null,"abstract":"<p><strong>Introduction: </strong>Intraoperative tumor thrombus embolization during renal cell carcinoma (RCC) surgery with inferior vena cava (IVC) tumor thrombus is a rare but potentially fatal complication. We report successful emergency cardiac surgery for massive pulmonary artery tumor embolism.</p><p><strong>Case presentation: </strong>A 75-year-old female with left RCC and IVC tumor thrombus underwent radical nephrectomy. Pre-existing left pulmonary artery tumor embolism was noted preoperatively. During IVC manipulation, the tumor thrombus dislodged and migrated through the right heart to completely occlude the right pulmonary artery, causing cardiac arrest. Through multidisciplinary collaboration, nephrectomy was completed under cardiac massage, followed by emergency cardiopulmonary bypass and pulmonary artery thrombectomy. The patient recovered completely without neurological sequelae.</p><p><strong>Conclusion: </strong>This case demonstrates the critical importance of preoperative risk assessment, intraoperative transesophageal echocardiography monitoring, and immediate multidisciplinary decision-making in managing this life-threatening complication. The \"double hit\" mechanism of pre-existing and acute pulmonary embolism significantly worsened the clinical course.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70168"},"PeriodicalIF":0.0,"publicationDate":"2026-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097613/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Renal Cell Carcinoma With Inferior Vena Cava Tumor Thrombus Achieving Pathologic Complete Response Following Combination Therapy With Lenvatinib and Pembrolizumab.","authors":"Hiroki Takayama, Takeshi Sano, Kento Hirao, Yusuke Motoki, Hisanori Taniguchi, Masaaki Yanishi, Katsunori Uchida, Hidefumi Kinoshita","doi":"10.1002/iju5.70165","DOIUrl":"https://doi.org/10.1002/iju5.70165","url":null,"abstract":"<p><strong>Introduction: </strong>The efficacy of neoadjuvant lenvatinib plus pembrolizumab for clear cell renal cell carcinoma with inferior vena cava tumor thrombus remains unclear.</p><p><strong>Case presentation: </strong>An 80-year-old man was diagnosed with clear cell renal cell carcinoma and tumor thrombus extending into the inferior vena cava. Following neoadjuvant lenvatinib plus pembrolizumab, the primary renal tumor shrank markedly, whereas the inferior vena cava tumor thrombus demonstrated only a slight reduction in size. Robot-assisted radical nephrectomy and lymphadenectomy were performed; however, conversion to open surgery was required because of an inferior vena cava laceration. Pathological examination revealed no residual viable cancer cells. The patient has remained free of recurrence for 1.5 years postoperatively.</p><p><strong>Conclusion: </strong>In this case, a pathological complete response was achieved following combination therapy of lenvatinib with pembrolizumab.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70165"},"PeriodicalIF":0.0,"publicationDate":"2026-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Successful Preservation of the Penis After en Bloc Resection of Locally Recurrent Rectal Cancer Involving the Left Crus of the Corpus Cavernosum and Corpus Spongiosum.","authors":"Tomonori Kanagawa, Masaya Ito, Misato Takao, Masahiro Toide, Shuichiro Kobayashi, Daisuke Nakano, Kazushige Kawai, Fumitaka Koga","doi":"10.1002/iju5.70164","DOIUrl":"https://doi.org/10.1002/iju5.70164","url":null,"abstract":"<p><strong>Introduction: </strong>We report a case of locally recurrent rectal cancer involving the penile base successfully treated with penis-preserving salvage surgery.</p><p><strong>Case presentation: </strong>A 63-year-old man underwent abdominoperineal resection for locally advanced rectal cancer, followed by three metastasectomies for inguinal lymph node recurrences and a pulmonary metastasis. Thirty-four months later, intrapelvic recurrences involving the seminal vesicle, prostate, left crus of corpus cavernosum penis (CCP), and corpus spongiosum (CS) developed. Following chemotherapy and chemoradiotherapy, cystoprostatectomy with en bloc resection of the left proximal CCP and proximal CS was performed while preserving the right crus of CCP where the internal pudendal artery (IPA) ran. Surgical margins were negative. No intrapelvic recurrence had developed until his decease from pulmonary metastasis in postoperative month 23.</p><p><strong>Conclusion: </strong>The penis can be preserved even after the unilateral crus of the CCP and the proximal CS are partially resected when the contralateral IPA blood flow is viable.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"9 2","pages":"e70164"},"PeriodicalIF":0.0,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13098089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147788795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}