IJU Case Reports最新文献

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Bladder Eversion Through a Vesicovaginal Fistula in a Patient With Complete Uterine Prolapse 完全性子宫脱垂患者膀胱外翻经膀胱阴道瘘一例
IJU Case Reports Pub Date : 2025-07-28 DOI: 10.1002/iju5.70064
Ryoken Tsunekawa, Naoki Wada, Haruka Takagi, Tsubasa Hatakeyama, Masaya Nagabuchi, Shun Morishita, Hidetoshi Ichikawa
{"title":"Bladder Eversion Through a Vesicovaginal Fistula in a Patient With Complete Uterine Prolapse","authors":"Ryoken Tsunekawa,&nbsp;Naoki Wada,&nbsp;Haruka Takagi,&nbsp;Tsubasa Hatakeyama,&nbsp;Masaya Nagabuchi,&nbsp;Shun Morishita,&nbsp;Hidetoshi Ichikawa","doi":"10.1002/iju5.70064","DOIUrl":"https://doi.org/10.1002/iju5.70064","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>We report a case of bladder eversion through a vesicovaginal fistula (VVF) in an elderly patient with severe pelvic organ prolapse (POP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 90-year-old woman presented with a sensation of prolapse and urinary leakage. She was diagnosed with complete uterine prolapse and bladder mucosal ectropion through a VVF, with renal dysfunction due to bilateral hydronephrosis. A one-stage minimally invasive surgical repair was performed. The VVF was then closed in two layers and reinforced with a Martius flap. Colpocleisis was performed without the addition of transvaginal hysterectomy. At 18 months after surgery, the patient remained free of POP and urinary incontinence.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In elderly patients, VVF can develop in advanced POP. Minimally invasive treatment is desirable, and early intervention for POP may help prevent this complication.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"458-461"},"PeriodicalIF":0.0,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70064","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitotane Treatment for Malignant Leydig Cell Tumor: A Case Report 米托坦治疗恶性间质细胞瘤1例
IJU Case Reports Pub Date : 2025-07-27 DOI: 10.1002/iju5.70078
Daiki Katsura, Mototsugu Muramaki, Takashi Okamoto, Masaya Yamamoto, Mizuki Yutaka, Shohei Morita, Takuya Fujimoto, Yuji Yamada
{"title":"Mitotane Treatment for Malignant Leydig Cell Tumor: A Case Report","authors":"Daiki Katsura,&nbsp;Mototsugu Muramaki,&nbsp;Takashi Okamoto,&nbsp;Masaya Yamamoto,&nbsp;Mizuki Yutaka,&nbsp;Shohei Morita,&nbsp;Takuya Fujimoto,&nbsp;Yuji Yamada","doi":"10.1002/iju5.70078","DOIUrl":"https://doi.org/10.1002/iju5.70078","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Leydig cell tumors (LCTs), constituting 1%–3% of testicular tumors, are mostly benign, but malignant cases present treatment challenges. We report a malignant LCT case with a notable response to mitotane.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 43-year-old male presented with a right testicular induration and was diagnosed with a Leydig cell tumor following orchiectomy. BEP chemotherapy was initiated for the liver metastases, but after four cycles, new lymph node and bone lesions appeared. Mitotane was started, which markedly reduced liver and nodal metastases. However, due to fatigue, anorexia, and nipple discomfort, mitotane was discontinued. The disease progressed, and the patient died 4 years post-diagnosis and 14 months after starting mitotane.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Mitotane shows promise in treating malignant LCTs, but careful management of adverse effects is necessary.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"498-502"},"PeriodicalIF":0.0,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunoglobulin G4-Related Inflammatory Pseudotumor With Cystic Features Mimicking Renal Cancer 具有类似肾癌囊性特征的免疫球蛋白g4相关炎性假瘤
IJU Case Reports Pub Date : 2025-07-27 DOI: 10.1002/iju5.70074
Yuki Tanaka, Takahisa Yamashita, Kazuki Yokota, Kenta Fujii, Sachi Kitayama, Shoichi Nagamoto, Hideki Takeshita, Yohei Okada, Satoru Kawakami, Akihiro Yano
{"title":"Immunoglobulin G4-Related Inflammatory Pseudotumor With Cystic Features Mimicking Renal Cancer","authors":"Yuki Tanaka,&nbsp;Takahisa Yamashita,&nbsp;Kazuki Yokota,&nbsp;Kenta Fujii,&nbsp;Sachi Kitayama,&nbsp;Shoichi Nagamoto,&nbsp;Hideki Takeshita,&nbsp;Yohei Okada,&nbsp;Satoru Kawakami,&nbsp;Akihiro Yano","doi":"10.1002/iju5.70074","DOIUrl":"https://doi.org/10.1002/iju5.70074","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Immunoglobulin G4-related disease is a systemic fibroinflammatory disorder that affects the kidney, presenting as an immunoglobulin G4-related inflammatory pseudotumor. These renal inflammatory pseudotumors are usually solid, and cystic presentations have not been previously described.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>We report a 77-year-old man who presented with a Bosniak category III renal cystic mass and periaortic fibrous thickening. Increased serum immunoglobulin G4 levels indicated immunoglobulin G4-related disease; however, a malignant process could not be definitively ruled out. The patient underwent robot-assisted radical nephrectomy, and histopathologic assessment confirmed a cystic immunoglobulin G4-related inflammatory pseudotumor.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This is the first report of a renal immunoglobulin G4-related inflammatory pseudotumor with cystic features. Increased knowledge of immunoglobulin G4-related disease as a potential cause of cystic renal lesions, particularly in patients with systemic findings, may improve preoperative diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"489-493"},"PeriodicalIF":0.0,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Urothelial Carcinoma With Squamous Differentiation of the Bladder, Infiltrating the Small Intestine and Rectus Abdominis, Treated With the Use of a Short Gracilis Myocutaneous Flap 尿路上皮癌伴膀胱鳞状分化,浸润小肠及腹直肌1例,短股薄肌肌皮瓣治疗
IJU Case Reports Pub Date : 2025-07-21 DOI: 10.1002/iju5.70077
Kazuto Imai, Norihiko Masuda, Tatsuya Hazama, Kanji Nagahama, Takashi Ito, Takakazu Matsushita, Yoko Muneta, Tadashi Inoue, Toshiya Akao
{"title":"A Case of Urothelial Carcinoma With Squamous Differentiation of the Bladder, Infiltrating the Small Intestine and Rectus Abdominis, Treated With the Use of a Short Gracilis Myocutaneous Flap","authors":"Kazuto Imai,&nbsp;Norihiko Masuda,&nbsp;Tatsuya Hazama,&nbsp;Kanji Nagahama,&nbsp;Takashi Ito,&nbsp;Takakazu Matsushita,&nbsp;Yoko Muneta,&nbsp;Tadashi Inoue,&nbsp;Toshiya Akao","doi":"10.1002/iju5.70077","DOIUrl":"https://doi.org/10.1002/iju5.70077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Squamous differentiation (SD) occurs in up to 20% of muscle invasive bladder cancers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>An 85-year-old man with an intrapelvic mass invading the bladder, small intestine, and rectus abdominis presented to our department. Cystoscopy showed a necrotic mass at the dome of the bladder. Histopathological examination of specimens from transurethral resection indicated squamous cell carcinoma. Radical cystectomy with resection of the small intestine and rectus abdominis, and reconstruction of the abdominal wall using a left short gracilis myocutaneous flap was performed. The histopathology showed squamous cell carcinoma and urothelial carcinoma (UC) components; findings consisted of UC with SD. The patient received appropriate flap management and treatment for postoperative complications and was discharged on postoperative Day 100.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>To our knowledge, this is the first report of an invasive bladder cancer with SD treated with the use of a short gracilis myocutaneous flap.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"494-497"},"PeriodicalIF":0.0,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144934828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Management of Tumor Lysis Syndrome Following Enfortumab Vedotin Plus Pembrolizumab Therapy in Metastatic Urothelial Carcinoma: A Case Report 在转移性尿路上皮癌中,安可单抗维多汀联合派姆单抗治疗后肿瘤溶解综合征的成功管理:1例报告
IJU Case Reports Pub Date : 2025-07-16 DOI: 10.1002/iju5.70069
Daigo Takemori, Ryu Shigehisa, Sho Shimasaki, Erika Yamashita, Yoshitaka Kurano, Kaya Atagi, Yuhi Ota, Shinkuro Yamamoto, Hiroto Osakabe, Tomoya Nao, Tsutomu Shimamoto, Hideo Fukuhara, Nobutaka Shimizu, Satoshi Fukata, Shingo Ashida, Keiji Inoue
{"title":"Successful Management of Tumor Lysis Syndrome Following Enfortumab Vedotin Plus Pembrolizumab Therapy in Metastatic Urothelial Carcinoma: A Case Report","authors":"Daigo Takemori,&nbsp;Ryu Shigehisa,&nbsp;Sho Shimasaki,&nbsp;Erika Yamashita,&nbsp;Yoshitaka Kurano,&nbsp;Kaya Atagi,&nbsp;Yuhi Ota,&nbsp;Shinkuro Yamamoto,&nbsp;Hiroto Osakabe,&nbsp;Tomoya Nao,&nbsp;Tsutomu Shimamoto,&nbsp;Hideo Fukuhara,&nbsp;Nobutaka Shimizu,&nbsp;Satoshi Fukata,&nbsp;Shingo Ashida,&nbsp;Keiji Inoue","doi":"10.1002/iju5.70069","DOIUrl":"https://doi.org/10.1002/iju5.70069","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Enfortumab vedotin plus pembrolizumab (EV + <i>P</i>) shows high efficacy in metastatic urothelial carcinoma (mUC), potentially increasing tumor lysis syndrome (TLS) risk.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 64-year-old man with mUC underwent surgery and adjuvant nivolumab after neoadjuvant chemotherapy. Five months post-surgery, EV + <i>P</i> was initiated for recurrence with distant metastasis. Non-contrast computed tomography on Day 15 of therapy revealed marked regression of hepatic and pulmonary metastases and significant reduction of the iliac soft tissue mass, with no evidence of infection. The following day, however, laboratory findings were consistent with TLS, followed by hypotension and respiratory failure. He was transferred to the intensive care unit for multidisciplinary supportive management. After stabilization, he was discharged home, and the second cycle of EV + <i>P</i> was completed uneventfully under prophylactic hydration and uric acid–lowering therapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Early recognition and timely multidisciplinary management are essential for favorable outcomes in TLS following EV + <i>P</i> therapy in mUC patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"470-474"},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70069","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Survival After Chemoradiotherapy for Renal Pelvis Cancer 肾盂癌放化疗后的长期生存率
IJU Case Reports Pub Date : 2025-07-15 DOI: 10.1002/iju5.70052
Yukinobu Shimada, Hiroyuki Kitano, Shunsuke Miyamoto, Kohei Kobatake, Keisuke Goto, Akihiro Goriki, Keisuke Hieda, Yutaka Hirokawa, Nobuyuki Hinata
{"title":"Long-Term Survival After Chemoradiotherapy for Renal Pelvis Cancer","authors":"Yukinobu Shimada,&nbsp;Hiroyuki Kitano,&nbsp;Shunsuke Miyamoto,&nbsp;Kohei Kobatake,&nbsp;Keisuke Goto,&nbsp;Akihiro Goriki,&nbsp;Keisuke Hieda,&nbsp;Yutaka Hirokawa,&nbsp;Nobuyuki Hinata","doi":"10.1002/iju5.70052","DOIUrl":"https://doi.org/10.1002/iju5.70052","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Despite the recent increase in applicable chemotherapy regimens for renal pelvic and ureteral cancer, patients with metastases still exhibit a poor prognosis. Here, we report a patient with renal pelvic cancer for whom long-term survival was achieved using chemoradiotherapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 62-year-old woman diagnosed with renal pelvic cancer showed indications of a right renal pelvic tumor with para-aortic and iliac lymph node metastasis on computed tomography. Radiotherapy doses of 55 and 66 Gy were administered to the primary lesion, para-aortic lymph node, and right iliac lymph nodes after chemotherapy with gemcitabine, cisplatin, and docetaxel. Five years after treatment, no recurrence was observed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Chemoradiotherapy is a potential therapeutic option for patients with renal pelvic carcinoma in whom surgical intervention is challenging owing to complications or older age.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"441-444"},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70052","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robot-Assisted Partial Nephrectomy for Multiple Synchronous Renal Tumors in Unilateral Kidney Using Hinotori Surgical System: A Case Report 应用Hinotori手术系统进行单侧肾脏多发同步性肾肿瘤的机器人辅助部分切除1例
IJU Case Reports Pub Date : 2025-07-15 DOI: 10.1002/iju5.70070
Kento Ozawa, Hiromitsu Watanabe, Kyohei Watanabe, Yuto Matsushita, Keita Tamura, Daisuke Motoyama, Atsushi Otsuka, Teruo Inamoto, Hideaki Miyake
{"title":"Robot-Assisted Partial Nephrectomy for Multiple Synchronous Renal Tumors in Unilateral Kidney Using Hinotori Surgical System: A Case Report","authors":"Kento Ozawa,&nbsp;Hiromitsu Watanabe,&nbsp;Kyohei Watanabe,&nbsp;Yuto Matsushita,&nbsp;Keita Tamura,&nbsp;Daisuke Motoyama,&nbsp;Atsushi Otsuka,&nbsp;Teruo Inamoto,&nbsp;Hideaki Miyake","doi":"10.1002/iju5.70070","DOIUrl":"https://doi.org/10.1002/iju5.70070","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Multiple synchronous renal tumors (MSRT) in unilateral kidney are clinically rare. Simultaneous resection for multiple tumors with RAPN is complicated and challenging. Herein, we report the successful resection of three synchronous renal tumors located in unilateral kidney with RAPN using the hinotori surgical robot system.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 75-year-old man was diagnosed with multiple left renal tumors (45 mm and 20 mm in diameter) that presented very close to each other. We performed RAPN using hinotori and excised the tumors simultaneously. Postoperative renal function was maintained. No complications were identified. The three histological types were distinct: ccRCC, pRCC, and small renal angiomyolipoma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>To the best of our knowledge, this is the first report of MSRT in unilateral kidney successfully treated with RAPN using hinotori.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"475-479"},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70070","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Renal Metastasis of Urothelial Carcinoma With Trophoblastic Differentiation Successfully Treated With Robot-Assisted Partial Nephrectomy 机器人辅助部分肾切除术成功治疗滋养细胞分化的尿路上皮癌肾转移1例
IJU Case Reports Pub Date : 2025-07-13 DOI: 10.1002/iju5.70072
Seiichiro Honda, Koichi Uemura, Hiroki Ito, Erika Muraoka, Tomoyuki Tatenuma, Yusuke Ito, Kentaro Muraoka, Hisashi Hasumi, Naomi Kawano, Shoji Yamanaka, Kazuhide Makiyama
{"title":"A Case of Renal Metastasis of Urothelial Carcinoma With Trophoblastic Differentiation Successfully Treated With Robot-Assisted Partial Nephrectomy","authors":"Seiichiro Honda,&nbsp;Koichi Uemura,&nbsp;Hiroki Ito,&nbsp;Erika Muraoka,&nbsp;Tomoyuki Tatenuma,&nbsp;Yusuke Ito,&nbsp;Kentaro Muraoka,&nbsp;Hisashi Hasumi,&nbsp;Naomi Kawano,&nbsp;Shoji Yamanaka,&nbsp;Kazuhide Makiyama","doi":"10.1002/iju5.70072","DOIUrl":"https://doi.org/10.1002/iju5.70072","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>There are no previous reports of solitary renal metastases from urothelial carcinoma with trophoblastic differentiation, a rare bladder cancer subtype that is pathologically hCGβ positive.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 77-year-old male with urothelial carcinoma with trophoblastic differentiation underwent robot-assisted radical cystectomy following neoadjuvant chemotherapy. Pathological examination revealed urothelial carcinoma, classified as ypT2b and ypN0 with detection of focal hCGβ positivity. Postoperatively, serum hCGβ levels decreased from 1.6 to &lt; 0.2 mIU/mL. At the 9-month follow-up, serum hCGβ was elevated to 20.1 mIU/mL with no recurrence on PET-CT. Gemcitabine–cisplatin chemotherapy was initiated; however, a solitary renal tumor was detected. Partial nephrectomy confirmed that the tumor was a renal metastasis of bladder cancer. Serum hCGβ levels decreased and remained &lt; 0.2 mIU/mL, even 20 months after partial nephrectomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We report a case of urothelial carcinoma with trophoblastic differentiation and elevated serum hCGβ levels, in which a solitary renal metastasis was successfully resected by robot-assisted partial nephrectomy.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"480-484"},"PeriodicalIF":0.0,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70072","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Malignant Melanoma Metastasis in the Ileal Conduit 恶性黑色素瘤回肠导管转移1例
IJU Case Reports Pub Date : 2025-07-10 DOI: 10.1002/iju5.70073
Noritoshi Shamoto, Yushi Naito, Yuta Sano, Kazuna Matsuo, Satoshi Inoue, Tomoyasu Sano, Tomokazu Kimura, Shohei Ishida, Yoshihisa Matsukawa, Shusuke Akamatsu
{"title":"A Case of Malignant Melanoma Metastasis in the Ileal Conduit","authors":"Noritoshi Shamoto,&nbsp;Yushi Naito,&nbsp;Yuta Sano,&nbsp;Kazuna Matsuo,&nbsp;Satoshi Inoue,&nbsp;Tomoyasu Sano,&nbsp;Tomokazu Kimura,&nbsp;Shohei Ishida,&nbsp;Yoshihisa Matsukawa,&nbsp;Shusuke Akamatsu","doi":"10.1002/iju5.70073","DOIUrl":"https://doi.org/10.1002/iju5.70073","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Tumor development in the ileal conduit is rare. Herein, we present a case of metastatic malignant melanoma occurring within the ileal conduit 17 years after radical cystectomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 76-year-old Japanese man, with a history of bladder cancer treated with radical cystectomy and ileal conduit diversion, presented with gross hematuria. He had malignant melanoma diagnosed 10 years prior, with recurrent metastases managed through surgery and adjuvant therapy. During his recent admission, metastases to the subcutaneous tissue and retroperitoneum were noted. Contrast-enhanced computed tomography revealed bilateral hydronephrosis and a tumor in the ileal conduit. Endoscopic resection confirmed metastatic malignant melanoma. The patient's renal function stabilized postoperatively, and hematuria was controlled. A palliative care approach was adopted to treat the melanoma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This rare case of metastatic malignant melanoma within an ileal conduit highlights the importance of histopathological examinations in patients with overlapping malignancies.</p>\u0000 \u0000 <p><b>Trial Registration:</b> 2016-0474</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 5","pages":"485-488"},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multiple Angiolipomas of the Spermatic Cord: A Case Report 精索多发性血管脂肪瘤1例
IJU Case Reports Pub Date : 2025-06-26 DOI: 10.1002/iju5.70061
Kazune Teshima, Tomoaki Hakariya, Daiyu Aoki, Naoki Nishimura, Shunsuke Sato, Masahiro Nakashima
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