IJU Case Reports最新文献

{"title":"Internal High Echoes Can Suggest the Possible Resection of Ovarian Vein Leiomyosarcoma: A Case Report","authors":"Sohei Iwagami,&nbsp;Shoji Oura,&nbsp;Masaya Nishihata","doi":"10.1002/iju5.70025","DOIUrl":"https://doi.org/10.1002/iju5.70025","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Leiomyosarcomas of ovarian veins often affect the IVC, the duodenum, and kidneys. Therefore, the resectability of the leiomyosarcomas highly depends on the presence or extent of their invasion to the surrounding organs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 55-year-old woman with a retroperitoneal mass on CT was referred to our hospital. CT and MRI showed a lobulated large mass with broad contact with the duodenum. EUS showed focal internal high echoes in the tumor areas adjacent to the duodenum. After obtaining the pathological diagnosis of leiomyosarcoma, the tumor was successfully removed without duodenum resection. Post-operative pathological findings confirmed the absence of direct leiomyosarcoma invasion to the duodenum and the sparse atypical cells with edematous background in the high internal echo areas.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Surgeons should note that internal high echoes in the tumor areas adjacent to the duodenum can be an important predictor of possible resection of the retroperitoneal tumors.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"315-318"},"PeriodicalIF":0.0,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70025","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Robot-Assisted Laparoscopic Radical Nephrectomy in a Renal Cell Carcinoma Patient With Severe Scoliosis: A Case Report","authors":"Tatsuya Kawamura,&nbsp;Daiki Ikarashi,&nbsp;Ayato Ito,&nbsp;Ei Shiomi,&nbsp;Shigekatsu Maekawa,&nbsp;Renpei Kato,&nbsp;Mitsugu Kanehira,&nbsp;Ryo Takata,&nbsp;Wataru Obara","doi":"10.1002/iju5.70037","DOIUrl":"https://doi.org/10.1002/iju5.70037","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Laparoscopic nephrectomy in patients with severe scoliosis presents significant challenges due to altered anatomy and limited space. This case report discusses using robot-assisted laparoscopic radical nephrectomy in such a scenario.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 68-year-old man with severe right convex scoliosis was diagnosed with cT3aN0M0 right locally advanced renal cell carcinoma. Given the anatomical distortions caused by scoliosis, traditional laparoscopic techniques posed difficulties. We opted for robot-assisted laparoscopic radical nephrectomy, carefully planning the port placement and surgical approach to accommodate the patient's unique anatomical features.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This is the first reported instance of robot-assisted laparoscopic radical nephrectomy in a patient with severe scoliosis. The successful outcome demonstrates the feasibility and benefits of robotic assistance in overcoming the technical difficulties associated with scoliosis, offering a viable surgical option for similar cases.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"352-355"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70037","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leuprorelin-Induced Thrombocytopenia Successfully Treated With Surgical Resection of the Injection Site","authors":"Ryota Mori,&nbsp;Satoru Taguchi,&nbsp;Masahiro Yamamoto,&nbsp;Yuta Inoue,&nbsp;Koichiro Kanazawa,&nbsp;Yoichi Fujii,&nbsp;Haesu Lee,&nbsp;Kiichi Furuse,&nbsp;Hiroaki Maki,&nbsp;Jun Kamei,&nbsp;Shigenori Kakutani,&nbsp;Yuta Yamada,&nbsp;Aya Niimi,&nbsp;Daisuke Yamada,&nbsp;Aya Shinozaki-Ushiku,&nbsp;Tetsuo Ushiku,&nbsp;Mineo Kurokawa,&nbsp;Mutsumi Okazaki,&nbsp;Haruki Kume","doi":"10.1002/iju5.70041","DOIUrl":"https://doi.org/10.1002/iju5.70041","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Drug-induced thrombocytopenia (DITP) can be caused by many kinds of drugs. Its treatment generally involves discontinuation of the responsible drug.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 70-year-old man received a subcutaneous injection of long-acting (24-week) leuprorelin depot as androgen deprivation therapy for prostate cancer. Four days after the injection, he presented with gingival bleeding and his platelet count was remarkably decreased (&lt; 1000/μL). There was no sign of malignancy but the presence of megakaryocytes on bone-marrow examinations. Considering immune and/or DITP, he started immunoglobulin and steroid therapy while stopping all suspected medications. However, even a month later, his platelet count did not recover with the need for frequent platelet transfusions. Therefore, he eventually underwent surgical resection of the leuprorelin injection site. After the surgery, his platelet count drastically recovered and platelet transfusion became unnecessary.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We report a case of leuprorelin-induced thrombocytopenia that was successfully treated with surgical resection of the injection site.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"365-368"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enfortumab Vedotin–Induced Toxic Epidermal Necrolysis in Metastatic Urothelial Carcinoma Complicated by Severe Gastrointestinal Bleeding","authors":"Aika Matsuyama,&nbsp;Takashi Kato,&nbsp;Rion Kawase,&nbsp;Mikinori Kobayashi,&nbsp;Ayako Momota,&nbsp;Yukiko Tsunoda,&nbsp;Asaomi Yamaguchi,&nbsp;Hiroki Hirabayashi,&nbsp;Shoji Suzuki,&nbsp;Masashi Kato","doi":"10.1002/iju5.70036","DOIUrl":"https://doi.org/10.1002/iju5.70036","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Enfortumab vedotin (EV) has been reported to cause skin toxicity in some patients. We report a rare case of toxic epidermal necrolysis (TEN) induced by EV and complicated by severe gastrointestinal (GI) bleeding.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 70-year-old man with recurrent urothelial carcinoma developed a trunk rash at 16 days after EV administration. He presented to the emergency department with loss of consciousness and was diagnosed with TEN and septic shock. Although pulse steroid therapy improved his skin lesions, his abdominal symptoms progressively worsened. On Day 27, he developed massive GI bleeding. Despite intensive interventions, he died of multiple organ failure on Day 30.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This case highlights that Stevens–Johnson syndrome/TEN induced by EV can develop shortly after treatment, with delayed and potentially fatal GI manifestations. Given the challenges in managing established TEN, close monitoring for adverse events is essential.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"348-351"},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70036","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of acute obstructive pyelonephritis due to bleeding from a renal pelvis cancer rescued with laparoscopic nephrectomy","authors":"Masato Yanagi,&nbsp;Ken Takahashi,&nbsp;Yuta Kikuchi,&nbsp;Takuya Takahashi,&nbsp;Hideaki Iwata,&nbsp;Hiro Izuta,&nbsp;Shuichi Osawa,&nbsp;Taiji Nishimura,&nbsp;Yukihiro Kondo","doi":"10.1002/iju5.12816","DOIUrl":"https://doi.org/10.1002/iju5.12816","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>We encountered a case of acute obstructive pyelonephritis caused by bleeding from a renal pelvis cancer that was successfully treated by laparoscopic nephrectomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case presentation</h3>\u0000 \u0000 <p>An 88-year-old woman with fever of 40.2°C and right back pain associated with hematuria due to a right renal pelvic tumor. Computed tomography showed a blood clot filling the right renal pelvis and ureter. She was diagnosed with severe obstructive pyelonephritis due to undrainable blood clots. Nephrectomy was performed to control the infection. Although the perirenal area was easy bleeding, nephrectomy was completed and the patient's condition improved.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Renal pelvis carcinomas with hemorrhage requiring blood transfusion should be treated with radical nephroureterectomy as early as possible.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"301-304"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.12816","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mesh Fixation to the Sacral Promontory From the Left Side of the Mesosigmoid: Two Cases of Robot-Assisted Sacrocolpopexy for Persistent Descending Mesocolon","authors":"Kojiro Tanabe,&nbsp;Yasuno Takahashi,&nbsp;Yuki Takahashi,&nbsp;Ryohei Hashimoto,&nbsp;Yoshiko Oyama,&nbsp;Yuko Hatakeyama,&nbsp;Hitoshi Niikura","doi":"10.1002/iju5.70039","DOIUrl":"https://doi.org/10.1002/iju5.70039","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Persistent descending mesocolon is a congenital fixation abnormality where the left-sided colon deviates medially. When significantly displaced to the right, it may affect sacrocolpopexy. We report two cases of persistent descending mesocolon in which robot-assisted sacrocolpopexy was successfully performed with mesh fixation to the sacral promontory from the left side of the mesosigmoid.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>Two patients with pelvic organ prolapse underwent robot-assisted sacrocolpopexy. In both cases, the sigmoid colon was displaced to the right, making exposure of the sacral promontory from the right side of the mesosigmoid challenging. Therefore, the sacral promontory was exposed and mesh fixed from the left side of the mesosigmoid. The postoperative course was uneventful.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>When the sigmoid colon is displaced rightward due to persistent descending mesocolon, sacral promontory fixation from the left mesosigmoid may be a safe, feasible option.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"356-360"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70039","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ureteroarterial fistula: Late infectious common iliac artery pseudoaneurysm formation following successful endovascular stenting and literature review","authors":"Shinnosuke Hiruta,&nbsp;Toshiaki Shinojima,&nbsp;Masao Takahashi,&nbsp;Takao Nonaka,&nbsp;Harunobu Matsumoto,&nbsp;Hirotaka Asakura","doi":"10.1002/iju5.70002","DOIUrl":"https://doi.org/10.1002/iju5.70002","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The long-term prognosis of endovascular stenting for ureteroarterial fistulas is not always favorable. We present a case in which endovascular repair of a ureteroarterial fistula led to the development of an infectious iliac artery pseudoaneurysm that required open vascular graft replacement 1 year later.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case presentation</h3>\u0000 \u0000 <p>A 38-year-old woman with radiation-induced vesicovaginal fistula and bilateral ureteral stenosis underwent urinary diversion using an ileal conduit. During left ureteral stent exchange, a ureteroarterial fistula occurred on the left side and was successfully treated with vascular stent grafting. One year later, gross hematuria recurred, requiring open surgical intervention because of the formation of an infectious pseudoaneurysm near the aortic bifurcation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Several patients treated with stent grafting for ureteroarterial fistulas require subsequent reintervention. Urologists managing patients with ureteroarterial fistulas should collaborate closely with interventional radiologists and vascular surgeons to ensure comprehensive care.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"305-309"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Advanced Renal Cell Carcinoma With Concomitant Development of Multiple Endocrine Neoplasia Type 1 That Affected Treatment Progress With Immunotherapy","authors":"Masataka Abe,&nbsp;Yoshiyuki Miyaji,&nbsp;Seitetsu Sugiyama,&nbsp;Kiwami Tsurui,&nbsp;Hirofumi Morinaka,&nbsp;Mikako Kaifu,&nbsp;Hiroyuki Kadoya,&nbsp;Wataru Saito,&nbsp;Koji Yoshida,&nbsp;Kazumasa Komura","doi":"10.1002/iju5.70034","DOIUrl":"https://doi.org/10.1002/iju5.70034","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Hypercalcemia is a poor prognostic factor in advanced cancer.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A patient with advanced clear cell renal carcinoma with hypercalcemia was treated with nivolumab+ipilimumab combination therapy. Treatment was discontinued after 4 months due to renal dysfunction. A detailed examination showed that the cause of hypercalcemia was hyperparathyroidism caused by multiple endocrine neoplasia type 1, and that renal dysfunction was attributed to the administration of zoledronic acid for the management of hypercalcemia. Following the suspension of cancer treatment, both the primary and metastatic lesions continued to shrink. A deferred nephrectomy was performed, and a pathological examination showed the absence of viable cancer cells in the specimen. Approximately 5 years after treatment, the patient is alive and cancer-free without treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Hypercalcemia due to hyperparathyroidism had an impact on treatment in this case. This underscores the importance of meticulous patient history-taking in medical practice.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"338-342"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70034","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Comment From Dr. Chelsea and Dr. Ranjana to Zinner Syndrome Presenting With Chronic Pelvic Pain and Ejaculatory Dysfunction","authors":"Chelsea Rachael Tafawa,&nbsp;Ranjana Sah","doi":"10.1002/iju5.70038","DOIUrl":"https://doi.org/10.1002/iju5.70038","url":null,"abstract":"<p>We read the report by Patil et al. with great interest; it effectively showcases the utility of conservative management in mildly symptomatic cases of Zinner syndrome, reinforcing the clinical principle of observation over intervention in the absence of disease progression [<span>1</span>]. Nevertheless, it offers a valuable context for reflecting on how surveillance strategies can evolve in such congenital anomalies. The decision to initiate empirical antibiotics and NSAIDs is clinically sound, yet future protocols might consider refining indications for antimicrobial use based on inflammatory markers or seminal plasma analysis, tools that can differentiate infectious from obstructive discomfort, especially in the absence of overt urinary tract infection [<span>2, 3</span>].</p><p>Another area worth discussing lies in the parameters guiding longitudinal follow-up. While 6-monthly semen analysis and imaging were proposed, outlining more specific clinical or biochemical triggers for potential escalation could enhance the generalizability of such a protocol. For example, establishing reference changes in semen motility or testicular volume may better anchor treatment thresholds.</p><p>The imaging findings were well articulated and provided excellent diagnostic clarity. However, recent studies suggest that seminal vesicle cysts with high proteinaceous content may benefit from biochemical analysis if aspiration is indicated in future cases [<span>4</span>]. Even when surgery is deferred, evolving imaging markers, such as cyst wall thickening or atypical signal patterns, might be integrated into future conservative frameworks to ensure safety.</p><p>This case demonstrates commendable clarity in the approach and contributes to an underrepresented segment of the urological literature. Its insights can further inform the development of structured, evidence-based algorithms for conservative management in young patients with fertility considerations.</p><p>The authors have nothing to report.</p><p>The authors have nothing to report.</p><p>The authors declare no conflicts of interest.</p>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"326-327"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70038","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Interstitial Cystitis With Hunner Lesions Involving Bilateral Ureters","authors":"Satoki Otsuka,&nbsp;Yoshiyuki Akiyama,&nbsp;Daichi Maeda,&nbsp;Aya Niimi,&nbsp;Kenichi Hashimoto,&nbsp;Jun Kamei,&nbsp;Satoru Taguchi,&nbsp;Yuta Yamada,&nbsp;Yusuke Sato,&nbsp;Daisuke Yamada,&nbsp;Tomonori Minagawa,&nbsp;Tetsuo Ushiku,&nbsp;Yukio Homma,&nbsp;Haruki Kume","doi":"10.1002/iju5.70010","DOIUrl":"https://doi.org/10.1002/iju5.70010","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Interstitial cystitis with Hunner lesion (IC/HL) is an enigmatic, chronic inflammatory disease of the urinary bladder. Few documented cases have reported the IC/HL involving the upper urinary tract.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Case Presentation</h3>\u0000 \u0000 <p>A 51-year-old Japanese woman with IC/HL developed bilateral ureteral stenosis and associated hydronephrosis, resulting in increased serum creatinine concentrations. Cystography showed no evidence of bilateral vesicoureteral reflux or bladder deformity. Ureteroscopy showed severe ureteral stenosis due to mucosal hyperplasia at the mid/upper levels of both ureters, leading to the insertion of bilateral ureteral stents. Histological examination of the ureteral lesions showed similar chronic inflammatory changes to the bladder lesions, which were compatible with IC/HL. Bilateral ureteral stenosis persisted after a two-year corticosteroid treatment (prednisolone, 7.5 mg/day), while IC/HL symptoms have disappeared.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>IC/HL could involve the upper ureters, and thus regular follow-up imaging of upper urinary tracts in patients with IC/HL is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"310-314"},"PeriodicalIF":0.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144525146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}