Syed Matthew Kodilinye, Vivek Kumbhari, Dilhana Badurdeen
{"title":"Complications of Metabolic and Bariatric Surgery for the Gastroenterologist: A Comprehensive Review.","authors":"Syed Matthew Kodilinye, Vivek Kumbhari, Dilhana Badurdeen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>By 2035, more than one-half of the global population is expected to have overweight or obesity, amounting to a substantial $4 trillion toll on the global economy. The uptake of metabolic and bariatric surgery has increased worldwide, providing treatment for both obesity and associated disorders of metabolic function. Laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass are the most commonly performed metabolic and bariatric surgical procedures. Despite advances in surgical techniques, complications are common and can occur long after surgery. This article provides gastroenterologists with a comprehensive compendium for understanding and managing the complications associated with metabolic and bariatric surgery.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 2","pages":"97-110"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920025/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ade Waterman, Stavros A Doumas, Michele Fischer, Mark Mattar, Samer Charbel, Joseph Jennings, David B Doman
{"title":"Uncovering the Hidden Link Between the Aberrant Intestinal Microbiome and Fibromyalgia.","authors":"Ade Waterman, Stavros A Doumas, Michele Fischer, Mark Mattar, Samer Charbel, Joseph Jennings, David B Doman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fibromyalgia is a multifaceted syndrome primarily characterized by chronic widespread pain and fatigue. Despite its significant prevalence and incidence, the mechanisms mediating the disease pathogenesis have remained poorly understood; however, increasing evidence suggests a potentially central role of intestinal dysbiosis. Researchers have been examining possible diagnostic biomarkers, such as <i>Helicobacter pylori</i> infection, urine metabolite profiles, and cytokine levels, which reflect these microbiome changes. Additionally, evaluation of therapeutic interventions targeting the gut microbiome, including probiotics, fecal microbiota transplantation, and antibiotics for specific infections, has highlighted their potential in alleviating fibromyalgia symptoms. This article delves into the emerging role of the gut microbiome in fibromyalgia pathogenesis, illustrating how alterations in gut bacterial composition and diversity are implicated in the pathophysiology of the disease through the gut-brain axis, and sets a direction for future research to enhance diagnostic accuracy and therapeutic efficacy of this complex condition.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 2","pages":"111-121"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"When the First Advanced Therapy Fails.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1 Suppl 1","pages":"9-11"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of Patients With Refractory Ulcerative Proctitis.","authors":"Michael V Chiorean","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 2","pages":"130-132"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11920024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring Glucagon-Like Peptide-1 Receptor Agonist Use in Inflammatory Bowel Disease Patients.","authors":"Gary R Lichtenstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1","pages":"7"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatocellular Carcinoma Surveillance Following Hepatitis C Virus Cure.","authors":"Paul Y Kwo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1","pages":"72-74"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
David J Cangemi, R Christopher Chase, Brian E Lacy
{"title":"Approach to Meal-Related Nausea and Vomiting.","authors":"David J Cangemi, R Christopher Chase, Brian E Lacy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Nausea and vomiting are common symptoms that frequently lead to evaluation in the outpatient and inpatient settings. The pathophysiology of nausea and vomiting is complex, and the list of potential etiologies is vast. Patients with nausea and vomiting frequently report that eating exacerbates symptoms. Noteworthy gastrointestinal causes for meal-related nausea and vomiting include gastroparesis, functional dyspepsia, dumping syndrome, superior mesenteric artery syndrome, and median arcuate ligament syndrome. A number of carefully selected diagnostic tests, utilization of the Rome criteria, and an appreciation for the epidemiology of these various conditions can help the clinician hone in on the underlying cause. Importantly, a properly performed and interpreted gastric emptying study is essential to making an accurate diagnosis of gastroparesis and distinguishing this condition from functional dyspepsia, a common disorder of gut-brain interaction. There are a number of treatment options for nausea and vomiting, and the treatment approach is dependent on the specific cause for the meal-related symptoms. This article examines the approach to meal-related nausea and vomiting by reviewing tests to consider in the diagnostic evaluation of symptoms, followed by a discussion of clinically relevant disorders and disorder-specific treatments.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1","pages":"19-27"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient-Provider Communication: The Key to Improving IBS-C Management.","authors":"Christina Hanson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1","pages":"28-39"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Approaches and Old Struggles in Antireflux Endoscopy.","authors":"Nikhil A Kumta","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Glucagon-Like Peptide-1 Receptor Agonists in Patients With Inflammatory Bowel Disease.","authors":"Christine Boumitri","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 1","pages":"59-61"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11784567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}