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Highlights From the Recent AASLD Practice Guidelines on Noninvasive Assessment of Hepatic Fibrosis and Steatosis. 美国肝脏病学会（AASLD）近期发布的肝纤维化和脂肪变性无创评估实践指南要点。
Gastroenterology and Hepatology Pub Date : 2024-10-01
Richard K Sterling
{"title":"Highlights From the Recent AASLD Practice Guidelines on Noninvasive Assessment of Hepatic Fibrosis and Steatosis.","authors":"Richard K Sterling","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"554-556"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights Into Resection for Esophageal Adenocarcinoma. 食管腺癌切除术的启示
Gastroenterology and Hepatology Pub Date : 2024-10-01
David M Poppers
{"title":"Insights Into Resection for Esophageal Adenocarcinoma.","authors":"David M Poppers","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"557-559"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cytomegalovirus Colitis in a Patient With Ulcerative Colitis With Loss of Corticosteroid Response Upon Upadacitinib Initiation. 一名溃疡性结肠炎患者患巨细胞病毒性结肠炎，且在服用乌达帕替尼后对皮质类固醇失去反应。
Gastroenterology and Hepatology Pub Date : 2024-10-01
Jonathan A Salazar, Jeffrey D Goldsmith, Athos Bousvaros, Michaela Tracy
{"title":"Cytomegalovirus Colitis in a Patient With Ulcerative Colitis With Loss of Corticosteroid Response Upon Upadacitinib Initiation.","authors":"Jonathan A Salazar, Jeffrey D Goldsmith, Athos Bousvaros, Michaela Tracy","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"546-549"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523084/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Strategies for Hepatocellular Carcinoma Surveillance. 肝细胞癌监测的新策略。
Gastroenterology and Hepatology Pub Date : 2024-10-01
Amit Singal
{"title":"Emerging Strategies for Hepatocellular Carcinoma Surveillance.","authors":"Amit Singal","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"560-562"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and Management of Noncardiac Chest Pain. 非心源性胸痛的诊断和处理。
Gastroenterology and Hepatology Pub Date : 2024-10-01
Tian Li, Manar Al Jawish, Dilhana Badurdeen, Andree H Koop
{"title":"Diagnosis and Management of Noncardiac Chest Pain.","authors":"Tian Li, Manar Al Jawish, Dilhana Badurdeen, Andree H Koop","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Noncardiac chest pain is a challenging condition often encountered by primary care providers, emergency medicine physicians, and gastroenterologists. It is frequently accompanied by persistent symptoms, diagnostic uncertainty, decreased quality of life, and high health care burden. Gastroesophageal reflux disease is the most common esophageal cause followed by functional chest pain, and at least half of patients with noncardiac chest pain have psychiatric comorbidities such as anxiety or depression. Management is focused on identification of an underlying cause to target treatment and address psychiatric comorbidities. This article discusses the evaluation and management of the common gastrointestinal causes of noncardiac chest pain.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"533-541"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosing and Treating Noncardiac Chest Pain. 诊断和治疗非心源性胸痛。
Gastroenterology and Hepatology Pub Date : 2024-10-01
Gary R Lichtenstein
{"title":"Diagnosing and Treating Noncardiac Chest Pain.","authors":"Gary R Lichtenstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"511"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clarifying the Hazy Concepts of Food Allergies and Sensitivities. 澄清食物过敏和敏感的模糊概念。
Gastroenterology and Hepatology Pub Date : 2024-10-01
Lauren Loeb, David C Cangemi, Jacqueline D Squire, Brian E Lacy
{"title":"Clarifying the Hazy Concepts of Food Allergies and Sensitivities.","authors":"Lauren Loeb, David C Cangemi, Jacqueline D Squire, Brian E Lacy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Food allergies, food sensitivities, and adverse reactions to food represent common reasons for gastroenterology and allergy referral. The epidemiology of these disorders is changing; food allergies are more common than previously thought, and there is a heightened sense of awareness about food sensitivities. Symptoms do not always accurately predict the underlying pathophysiology nor distinguish the underlying etiology. This may lead to unnecessary testing, which is often unrewarding and expensive. Myths and misconceptions about food allergies and sensitivities are common and may lead to unwarranted treatment using untested therapies. Importantly, a missed diagnosis of a true food allergy can have serious consequences. This article discusses the differences between food allergies and sensitivities, including their epidemiology, underlying pathophysiology, key symptoms, and diagnostic criteria, as well as their treatment options.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 9","pages":"524-531"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11523085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Helicobacter pylori Antimicrobial Resistance and the Role of Next-Generation Sequencing. 幽门螺杆菌的抗菌耐药性和新一代测序技术的作用。
Gastroenterology and Hepatology Pub Date : 2024-08-01
Christine B Andrews, Michael I Herzlinger, Steven F Moss
{"title":"<i>Helicobacter pylori</i> Antimicrobial Resistance and the Role of Next-Generation Sequencing.","authors":"Christine B Andrews, Michael I Herzlinger, Steven F Moss","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><i>Helicobacter pylori</i> infection affects over half of the world's population and is a global health concern because it contributes to chronic and fatal gastrointestinal disorders, including peptic ulcer disease and gastric cancer. The escalating prevalence of antibiotic-resistant strains of <i>H pylori</i> necessitates a change in management. The conventional strategy of empiric-based treatments is becoming increasingly ineffective in both adult and pediatric populations; rates of eradication to common first-line regimens remain suboptimal and continue to decline. Culture-based susceptibility testing for <i>H pylori</i> has been underutilized and challenging to incorporate into practice. Next-generation sequencing (NGS), which can identify the genetic biomarkers that predict antimicrobial resistance and susceptibility patterns, offers a promising alternative. NGS may enable clinicians to tailor individual treatment regimens and contribute to epidemiologic surveillance across populations. As NGS technology advances and becomes more accessible, its integration into routine clinical practice holds the potential to transform <i>H pylori</i> management strategies and improve patient outcomes. This article reviews the literature describing antimicrobial resistance patterns in adult and pediatric practice in the United States and provides practical guidance on the current role of NGS in the management of <i>H pylori.</i></p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 8","pages":"469-476"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Suggested Relationships Between Common GI Symptoms and Joint Hypermobility, POTS, and MCAS. 常见消化道症状与关节过度活动症、POTS 和 MCAS 之间的关系。
Gastroenterology and Hepatology Pub Date : 2024-08-01
Eamonn M M Quigley, Oscar Noble, Usman Ansari
{"title":"The Suggested Relationships Between Common GI Symptoms and Joint Hypermobility, POTS, and MCAS.","authors":"Eamonn M M Quigley, Oscar Noble, Usman Ansari","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An increasing number of reports suggest an association between a newly recognized disease cluster and significant and often disabling gastrointestinal (GI) symptoms. This cluster is composed of diagnoses of hypermobility spectrum disorders (HSDs) such as joint hypermobility and hypermobile variant Ehlers-Danlos syndrome (hEDS), postural orthostatic tachycardia syndrome (POTS), and mast cell activation syndrome (MCAS). The diagnosis of these entities remains a challenge, as the pathophysiology of each has not been completely elucidated and the diagnostic criteria continue to evolve. This article describes a cohort of young adult females who shared similar GI symptoms, with intractable nausea and vomiting being most prominent and gastroesophageal reflux disease and constipation also occurring. Most strikingly, these females also exhibited or reported a history of HSD, hEDS, POTS, and/or MCAS. The clinical course of their GI symptoms was remarkable for considerable challenges in management, and artificial nutritional support proved necessary for some. This article describes the clinical features and outcomes of their GI manifestations, examines how these manifestations might be linked to their systemic syndromes, and discusses whether a shared pathophysiology exists. Pending the definition of a common thread between these conditions, this article seeks to raise awareness of their clinical definitions and foster research that will hopefully improve outcomes for these patients.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 8","pages":"479-489"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11348541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conventional vs Full-Thickness Resection Techniques for Large Polyps. 大息肉的传统切除技术与全厚切除技术的比较
Gastroenterology and Hepatology Pub Date : 2024-08-01
Arthur Schmidt
{"title":"Conventional vs Full-Thickness Resection Techniques for Large Polyps.","authors":"Arthur Schmidt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"20 5","pages":"294-296"},"PeriodicalIF":0.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11345993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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