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Gastroenterology and Hepatology最新文献

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Low Remission Recapture After Ustekinumab Dose Optimization in CD: Results of the Randomized Placebo-Controlled Double-Blind REScUE Study. Ustekinumab剂量优化后的低缓解复发：随机安慰剂对照双盲救援研究的结果。
Gastroenterology and Hepatology Pub Date : 2025-08-01
{"title":"Low Remission Recapture After Ustekinumab Dose Optimization in CD: Results of the Randomized Placebo-Controlled Double-Blind REScUE Study.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7 Suppl 5","pages":"14-15"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to Approach Immune Checkpoint Inhibitor Enterocolitis. 如何治疗免疫检查点抑制剂小肠结肠炎。
Gastroenterology and Hepatology Pub Date : 2025-08-01
Yinghong Mimi Wang
{"title":"How to Approach Immune Checkpoint Inhibitor Enterocolitis.","authors":"Yinghong Mimi Wang","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 8","pages":"501-503"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397779/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Efficacy and Safety of Mirikizumab Following 104 Weeks of Continuous Treatment for CD: Results From the VIVID-2 Open-Label Extension Study. Mirikizumab连续治疗CD 104周后的长期疗效和安全性：来自于fresh 2开放标签扩展研究的结果
Gastroenterology and Hepatology Pub Date : 2025-08-01
{"title":"Long-Term Efficacy and Safety of Mirikizumab Following 104 Weeks of Continuous Treatment for CD: Results From the VIVID-2 Open-Label Extension Study.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7 Suppl 5","pages":"17-18"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-Targeted Therapy With Risankizumab and Upadacitinib Is Clinically and Biochemically Effective in Medically Complex CD. 利桑单抗和Upadacitinib双靶向治疗在临床上和生物化学上是有效的。
Gastroenterology and Hepatology Pub Date : 2025-08-01
{"title":"Dual-Targeted Therapy With Risankizumab and Upadacitinib Is Clinically and Biochemically Effective in Medically Complex CD.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7 Suppl 5","pages":"15-16"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Irritable Bowel Syndrome in Inflammatory Bowel Disease Patients: Prevalence, Etiology, and Treatment. 炎症性肠病患者肠易激综合征：患病率、病因学和治疗。
Gastroenterology and Hepatology Pub Date : 2025-07-01
David J Gracie, Alexander C Ford
{"title":"Irritable Bowel Syndrome in Inflammatory Bowel Disease Patients: Prevalence, Etiology, and Treatment.","authors":"David J Gracie, Alexander C Ford","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>One in 4 patients with endoscopically confirmed quiescent inflammatory bowel disease (IBD) reports persistent gastrointestinal symptoms, which are often compatible with irritable bowel syndrome (IBS). The reporting of these IBS-type symptoms is associated with psychological comorbidity, impaired quality of life, and increased health care utilization. The brain-gut axis, which provides the link between the central nervous system and gastrointestinal tract, may facilitate these relationships. In IBS, dietary manipulation, gut-brain neuromodulators, and brain-gut behavioral therapies may have a beneficial effect on symptom reporting and quality of life. However, evidence supporting their use in patients reporting IBS-type symptoms specifically in IBD is lacking. Despite this, observational studies describing the relationship between mood and inflammatory activity highlight the role of the brain-gut axis in the pathophysiology of IBD. There remains a need for further carefully designed clinical trials of treatments targeting the brain-gut axis in IBD patients reporting IBS-type symptoms, who may be most likely to respond to these therapies. An integrated approach to management, combining treatments targeting inflammatory activity and brain-gut axis dysfunction, has the potential to improve the natural history of symptoms, psychological well-being, and quality of life in this select group of patients with IBD. This article will review the prevalence, impact, etiology, and treatment options for the management of patients with quiescent IBD who report IBS-type symptoms.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"415-423"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Provider Conversation About IBS-C Treatment With Tenapanor. 关于Tenapanor治疗IBS-C的患者-提供者对话
Gastroenterology and Hepatology Pub Date : 2025-07-01
Christina Hanson
{"title":"Patient-Provider Conversation About IBS-C Treatment With Tenapanor.","authors":"Christina Hanson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"454-455"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Irritable Bowel Syndrome Symptoms in Patients With Inflammatory Bowel Disease. 炎性肠病患者肠易激综合征症状的探讨
Gastroenterology and Hepatology Pub Date : 2025-07-01
Gary R Lichtenstein
{"title":"Exploring Irritable Bowel Syndrome Symptoms in Patients With Inflammatory Bowel Disease.","authors":"Gary R Lichtenstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"407"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Checkpoint Inhibitor Combinations for Hepatocellular Carcinoma Treatment. 检查点抑制剂联合治疗肝细胞癌。
Gastroenterology and Hepatology Pub Date : 2025-07-01
Laura M Kulik
{"title":"Checkpoint Inhibitor Combinations for Hepatocellular Carcinoma Treatment.","authors":"Laura M Kulik","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"456-458"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397792/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tips and Tricks for Success With Endoscopic Clips. 提示和技巧成功与内窥镜剪辑。
Gastroenterology and Hepatology Pub Date : 2025-07-01
Klaus Mönkemüller
{"title":"Tips and Tricks for Success With Endoscopic Clips.","authors":"Klaus Mönkemüller","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"441-444"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Status of Fecal Microbiota Transplantation for Inflammatory Bowel Disease Management. 粪便微生物群移植治疗炎症性肠病的现状。
Gastroenterology and Hepatology Pub Date : 2025-07-01
Jessica R Allegretti
{"title":"Current Status of Fecal Microbiota Transplantation for Inflammatory Bowel Disease Management.","authors":"Jessica R Allegretti","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"451-453"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397791/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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