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Update on Organ Allocation and Liver Transplantation. 器官分配与肝移植的最新进展。
Gastroenterology and Hepatology Pub Date : 2025-07-01
Sunny Sandhu, David Goldberg
{"title":"Update on Organ Allocation and Liver Transplantation.","authors":"Sunny Sandhu, David Goldberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Liver transplantation remains a lifesaving intervention for patients with end-stage liver disease; however, organ demand continues to far exceed the supply. The core ethical principles that guide scarce resource allocation include utility, equity, and prioritization of the sickest patients. Implementation of national organ allocation and distribution policy updates over the years have led to several positive changes, including earlier transplant of livers from sicker patients and decreased waitlist mortality rates. Current practices include utilization of the Model for End-Stage Liver Disease score to determine waitlist priority, with distribution protocols involving the use of the acuity circle model. Despite these improvements, geographic and socioeconomic disparities remain. This article reviews the history of liver allocation and distribution practices, the successes and challenges of current policies, and future frameworks aimed at providing equitable approaches to matching donors with candidates.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"424-430"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Patients With Refractory Ascites. 难治性腹水患者的处理。
Gastroenterology and Hepatology Pub Date : 2025-07-01
Sumeet Asrani
{"title":"Management of Patients With Refractory Ascites.","authors":"Sumeet Asrani","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 7","pages":"431-433"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining Exercise in Metabolic Dysfunction-Associated Steatohepatitis. 运动对代谢功能障碍相关脂肪性肝炎的影响。
Gastroenterology and Hepatology Pub Date : 2025-06-01
Gary R Lichtenstein
{"title":"Examining Exercise in Metabolic Dysfunction-Associated Steatohepatitis.","authors":"Gary R Lichtenstein","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"339"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylaxis for Spontaneous Bacterial Peritonitis. 自发性细菌性腹膜炎的预防。
Gastroenterology and Hepatology Pub Date : 2025-06-01
Richard K Sterling
{"title":"Prophylaxis for Spontaneous Bacterial Peritonitis.","authors":"Richard K Sterling","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"377-379"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-Centered Approach in IBS-C Management. 以患者为中心的IBS-C管理方法。
Gastroenterology and Hepatology Pub Date : 2025-06-01
Kavita Kongara
{"title":"Patient-Centered Approach in IBS-C Management.","authors":"Kavita Kongara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"362-373"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond the Scope: The Promise and Limitations of Blood-Based Colorectal Cancer Screening. 超出范围：基于血液的结直肠癌筛查的希望和局限性。
Gastroenterology and Hepatology Pub Date : 2025-06-01
Jason A Dominitz
{"title":"Beyond the Scope: The Promise and Limitations of Blood-Based Colorectal Cancer Screening.","authors":"Jason A Dominitz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"397-399"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Eosinophilic Esophagitis Predispose to Achalasia? 嗜酸性食管炎易致贲门失弛缓症吗？
Gastroenterology and Hepatology Pub Date : 2025-06-01
Stuart J Spechler
{"title":"Does Eosinophilic Esophagitis Predispose to Achalasia?","authors":"Stuart J Spechler","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"394-396"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Approaches to Screening for Barrett Esophagus. Barrett食管筛查的新方法。
Gastroenterology and Hepatology Pub Date : 2025-06-01
Nicholas Shaheen, Prasad Iyer, Swathi Eluri
{"title":"New Approaches to Screening for Barrett Esophagus.","authors":"Nicholas Shaheen, Prasad Iyer, Swathi Eluri","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Current screening methods for Barrett esophagus (BE), the precursor to esophageal adenocarcinoma (EAC), are inadequate with less than one-third of screen-eligible patients currently undergoing screening. In addition to low screening rates, key issues include overemphasis on gastroesophageal reflux disease symptoms and lack of provider awareness, owing in part to heterogeneous guidelines. To address these challenges, several new approaches are being explored: swallowable cell collection devices, exhaled volatile organic compounds analysis, blood-based molecular biomarkers, microbiome analysis, and alternative visualization methods such as transnasal and capsule endos-copy. Proposed strategies to improve BE screening integrate enhanced risk stratification tools using machine learning and electronic health record data, noninvasive screening for low-risk patients, traditional endoscopy for high-risk patients, primary care education, and public health initiatives to increase awareness. This article highlights the latest developments in BE detection, including noninvasive screening methods and strategies to improve risk stratification, that have the potential to reduce EAC incidence and mortality.</p>","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"353-361"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise in Patients With Metabolic Dysfunction-Associated Steatohepatitis. 运动对代谢功能障碍相关脂肪性肝炎患者的影响
Gastroenterology and Hepatology Pub Date : 2025-06-01
Jonathan G Stine
{"title":"Exercise in Patients With Metabolic Dysfunction-Associated Steatohepatitis.","authors":"Jonathan G Stine","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"390-393"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treating Patients With Inflammatory Bowel Disease During and After Cancer. 在癌症期间和之后治疗炎症性肠病患者。
Gastroenterology and Hepatology Pub Date : 2025-06-01
Jordan Axelrad
{"title":"Treating Patients With Inflammatory Bowel Disease During and After Cancer.","authors":"Jordan Axelrad","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":52498,"journal":{"name":"Gastroenterology and Hepatology","volume":"21 6","pages":"387-389"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12397801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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