Journal of Bioresources and Bioproducts最新文献

{"title":"Structural characteristics of hemicelluloses and lignin-carbohydrate complexes in alkaline-extracted bamboo green, core, and yellow","authors":"Xin Wang ,&nbsp;Yang Liu ,&nbsp;Shiyu Luo ,&nbsp;Baojie Liu ,&nbsp;Shuangquan Yao ,&nbsp;Chengrong Qin ,&nbsp;Shuangfei Wang ,&nbsp;Chen Liang","doi":"10.1016/j.jobab.2025.01.004","DOIUrl":"10.1016/j.jobab.2025.01.004","url":null,"abstract":"<div><div>Understanding the differences in the chemical structures of important components in different bamboo tissues is crucial for maximizing bamboo utilization and biorefining bamboo resources. Hemicellulose and lignin-carbohydrate complex (LCC) were extracted from bamboo green, bamboo core, and bamboo yellow tissues by using the alkali-leaching method, and the chemical composition, thermal stability, dissolution process, and structural characteristics were analyzed. The extraction yield of hemicelluloses followed the order: bamboo yellow &gt; bamboo core &gt; bamboo green. Hemicelluloses extracted from bamboo green mainly originated from the secondary wall (S-layer) of the fiber cells and parenchyma cell walls, while those from the bamboo core and yellow mainly originated from the inner S-layer and outer S-layer of the fiber cells, as well as the parenchyma cell walls. The LCCs from bamboo core and bamboo yellow contained a large number of type I phenyl glycoside (PhGlc₁) bonds, which mainly originated from the parenchyma cell walls of these tissues. These findings provide data on the structural differences between carbohydrate components in green, core, and yellow bamboo, offering valuable guidance for the high-value utilization of different bamboo tissues.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 386-396"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabricating ultra-robust hydrogels with adhesive properties by restraining crack propagation with bamboo cellulose-based carbon nanomaterials","authors":"Xin Duan ,&nbsp;Huanxin Huo ,&nbsp;Hongshan Li ,&nbsp;Yihong Gao ,&nbsp;Haoran Shi ,&nbsp;Feng Kuang ,&nbsp;Yumeng Chen ,&nbsp;Jianyong Wan ,&nbsp;Jingjie Shen ,&nbsp;Guanben Du ,&nbsp;Long Yang","doi":"10.1016/j.jobab.2025.05.002","DOIUrl":"10.1016/j.jobab.2025.05.002","url":null,"abstract":"<div><div>The bamboo fiber functionalized with phthalic anhydride underwent carbonization, yielding bamboo cellulose-derived carbon nanomaterials (C-BCN). These C-BCN were subsequently integrated into an acrylamide precursor solution to synthesize an ultra-robust, fatigue-resistant conductive hydrogel (PAM-C-BCN). During in situ polymerization, the abundant active sites on the C-BCN surface facilitated covalent cross-linking with the polyacrylamide (PAM) matrix. This interfacial interaction promoted strong adhesion between the PAM chains and the carbon nanostructures, forming a densely interpenetrated network through macromolecular entanglement. The synergistic coupling of the rigid C-BCN framework with the flexible polymer chains conferred exceptional mechanical resilience and energy dissipation capabilities to the composite hydrogel. Compared to the PAM hydrogel, the PAM-C-BCN hydrogel exhibited an improvement in mechanical properties, with a fracture strength of 363 kPa (a 2.5% increase), an elongation of approximately 2 254% (a 2.0% increase), a fracture energy of 30 kJ/m² (a 3.1% increase), and a toughness of 3.04 MJ/m³ (a 4.1% increase). Moreover, PAM-C-BCN hydrogel demonstrated high adhesion (up to 7.5 kPa on pigskin) and conductivity (0.21 S/m). This strategy required neither complex design nor processing, offering a simple and efficient approach with great potential for hydrogel applications requiring high mechanical performance. At the crack tip of PAM-C-BCN hydrogel, C-BCN exhibited superior crack propagation resistance compared to SiO₂ nanoparticles. Importantly, this strategy offered valuable insights for developing tough and stretchable hydrogels.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 360-372"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kraft lignin as wet-strength and wet-stiffness additives for molded pulp materials","authors":"Eva Pasquier,&nbsp;Jost Ruwoldt","doi":"10.1016/j.jobab.2025.05.001","DOIUrl":"10.1016/j.jobab.2025.05.001","url":null,"abstract":"<div><div>Derived from renewable resources, cellulose based materials are gaining new importance due to their recyclability and biodegradability. Still, one fundamental challenge is their high sensitivity to water. The addition of wet strength agents (WSA) is hence necessary to maintain strength and integrity in humid or wet conditions. In this article, technical lignin was used as WSA in bleached kraft pulp, which was thermopressed to materials with the potential to replace plastics. Cationic starch or a cationic flocculant (PCB 20) was used as a retention aid during the filtration process. The effect of moisture during thermopressing and lignin particle size were also studied. The results showed that elevated moisture during pressing had the biggest impact both on dry and wet strength. Wet strength (tensile test), up to 9 MPa, and wet strength retention, up to 12 %, were obtained when moisture was present during pressing. However, the type of flocculant and the size of the lignin particles also had a limited effect on the strength. Wet strength improvement was most probably due to the plasticization of lignin at high temperatures, which was further aided by water. The cellulose-lignin network was strengthened by the melting of lignin, consolidating the network after cooling. The wet stiffness of the cellulose substrates was also increased from 200 to 938 MPa in the presence of lignin, while the elongation was maintained and no embrittlement was observed. The results in this article might hence pave the way for new developments in molded pulp and cellulose based plastics replacement.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 325-335"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial and biodegradable bandage with exudate absorption and smart monitoring for chronic wound management","authors":"Zhaochuan Yu ,&nbsp;Hao Wu ,&nbsp;Xing Zhang ,&nbsp;Yang Jiang ,&nbsp;Chao Liu ,&nbsp;Yuqian Liu ,&nbsp;Farzad Seidi ,&nbsp;Chao Deng","doi":"10.1016/j.jobab.2025.06.001","DOIUrl":"10.1016/j.jobab.2025.06.001","url":null,"abstract":"<div><div>Despite the promising potential of smart bandages in wound care, the lack of effective integration among infection control, exudate management, and real-time wound monitoring remains a major obstacle in clinical application. Herein, neomycin (NEO)-grafted cellulose-based nonwovens (CNs) were used as the antibacterial network and blueberry extract (anthocyanin, AC) as the colorimetric additive to create the excellent dual network gel (DNG) bandage for smart bandages along with a polyvinyl alcohol/cellulose nanofiber (PVA/CNFs) matrix. The aerogel bandage loaded with AC demonstrates a pH-sensitive color-changing response and high-efficiency free radical scavenging ability (all greater than 93.61%), enabling the in-situ monitoring of wound healing and inhibiting wound inflammation, while the nonwoven network grafted with NEO endows the aerogel composites with excellent antibacterial properties (&gt;99% against <em>Staphylococcus aureus</em> and <em>Escherichia coli</em>). In vivo evaluation using a <em>S. aureus</em>-infected full-thickness wound model in mice demonstrated that the DNG bandage significantly accelerated wound healing and improved tissue regeneration, outperforming commercial dressings. Furthermore, upon absorbing exudate, the aerogel converts into a hydrogel, providing efficient fluid absorption and preventing wound re-contamination, thereby achieving dynamic exudate management. Evidently, the DNG smart bandage is a promising management tool for the synergistic treatment of persistent wounds and introduces a fresh strategy for medical regenerative medicine.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 373-385"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anion exchangers prepared from graft polymerisation of microfibrillated cellulose using the reactive ionic liquid","authors":"Muzamil Jalil Ahmed ,&nbsp;Baohu Wu ,&nbsp;Antoni Sánchez-Ferrer","doi":"10.1016/j.jobab.2025.04.001","DOIUrl":"10.1016/j.jobab.2025.04.001","url":null,"abstract":"<div><div>Microfibrillated cellulose (MFC) was functionalised using a reactive ionic liquid monomer, <em>i.e.</em>, glycidyltriethylammonium chloride (GTEAC), via chain-growth polymerisation, resulting in a novel cationic polyelectrolyte-grafted quaternised MFC (QMFC). The degree of quaternisation and maximum ion exchange capacity of the resulting QMFC were 2.13 mmol/g (<em>i.e.</em>, 132 mg/g) and 1.51 mmol/g (<em>i.e.</em>, 94 mg/g), respectively. Small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) experiments confirmed the retention of monoclinic crystalline structure for cellulose I with the corresponding decrease in the degree of crystallinity from 85% to 56% and the increase in the spacing between cellulose crystallites by 35%. The presence of the amorphous and grafted polymers was confirmed by microscopy, thermal analysis, and water sorption experiments. QMFC filter cartridges were prepared and tested under dynamic flow conditions with a pressure of 0.2 MPa (retention time of 0.5 min). These cationic polyelectrolytes enhanced multi-site ion exchange interactions as evidenced by the Freundlich sorption isotherm. The QMFC filter cartridges demonstrated high anion removal efficiency values of 83.2%, 98.1%, and 94.9% for NO₃⁻, SO₄²⁻, and PO₄³⁻, respectively. This system achieved a process mass efficiency of 2.79, an <em>E</em>-factor of 1.97, and an energy efficiency score of 66.3, which conforms to the green chemistry principles and demonstrates high potential for sustainable water purification.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 310-324"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Splitting the difference: Genetically-tunable mycelial films using natural genetic variations in schizophyllum commune","authors":"Viraj Whabi,&nbsp;Jianping Xu","doi":"10.1016/j.jobab.2025.05.004","DOIUrl":"10.1016/j.jobab.2025.05.004","url":null,"abstract":"<div><div>Fungal mycelium, renowned for its robust fiber structure, is gaining widespread attention as a sustainable alternative to traditional plastics and textiles. Strain optimization offers the opportunity to improve these mycelial materials by systematically selecting specific phenotypes that have ideal mechanical and physiochemical properties. <em>Schizophyllum commune</em>, the common split gill mushroom, is a cosmopolitan species with over 23 000 mating types and abundant genetic diversity. In this study, this species was used as a model to explore the potential of leveraging natural genetic variation within species to develop fungal mycelial materials with diverse properties. Specifically, four divergent monokaryotic strains of <em>S. commune</em> sourced globally were selected, and through mating, 12 dikaryotic progeny, each with their unique combinations of nuclear and mitochondrial deoxyribonucleic acid (DNA) were derived. These 16 strains were assessed for their growth in both solid and liquid media. Their mycelia from liquid media were further processed, including by linking with two different crosslinkers, polyethylene glycol 400, and glycerol, to form mycelial films. Mechanical testing and surface characterization showed that the mycelial films differed greatly in a diversity of features, from water retention to strength, ductility, morphology, and hydrophobicity. Moreover, Fourier transform infrared spectroscopy showed that different strains had unique chemical fingerprints revealing diverse cell wall composition that interfaced with each of the crosslinkers uniquely. Statistical analyses revealed that, along with the highly influential crosslinker effects, nuclear-mitochondrial genotype interactions were key factors in tuning the performances of these materials. The two-layer tunability of the fungal materials points to the novel potential for genetically optimized strains, such as through protoplasting to separate nuclei in dikaryons to monokaryons with new nuclear-mitochondrial combinations and/or protoplast fusion to artificially create novel dikaryons, with tailored mycelial materials properties for applications in textiles, coatings, and mycoremediation.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 336-359"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive, non-enzymatic, non-serodiagnostic, and home-detecting paper-based “abnormal UA alarm” for early diagnosis of UA associated diseases","authors":"Qian Zhang ,&nbsp;Hui’e Jiang ,&nbsp;Zhijian Li ,&nbsp;Lijuan Chen ,&nbsp;Fengqian Yang ,&nbsp;Jiamin Zhang ,&nbsp;Bo Zhang ,&nbsp;Xinhua Liu","doi":"10.1016/j.jobab.2025.06.002","DOIUrl":"10.1016/j.jobab.2025.06.002","url":null,"abstract":"<div><div>Uric acid (UA) level is a pivotal clinical human-health biomarker providing predictive feedback for multitudinous well-known kidney, cardiovascular and metabolic syndrome diseases. Off-the-shelf UA detection methods clinically rely on uricase suffer from limitations such as high costs, longstanding result acquisition, circumscribed testing locations, rigorous expertise requirements, and difficulty in home-detecting due to serum testing systems. Here, inspired by the pH-paper, a scaleable, rapid, non-invasive/-enzymatic/-serodiagnostic, and home-detecting “abnormal UA alarm” platform for UA detection in saliva was developed by strategically integrating the proposed paper-based fluorescent sensing-materials (NIFP-SM) with a user-orientated intelligent red-green-blue (RGB) analysis device. Therefore, NIFP-SM is nano-engineered through straightforward interfacial interactions of functional building blocks of on-demand naphthyl imide-derived fluorescent self-assembled micro-particles (NIFS) with lamellar structure and commercially-used filter paper. The NIFS possesses dominantly wide detection range (0–5 000 µmol/L) and high sensitivity (limit of detection = 0.91 µmol/L). Surprisingly, NIFS exhibited outstanding identifiability for uric acid even in the presence of 34 interferents, substantiating accurate detection-capability in intricate environments. Thus NIFP-SM equipped with NIFS resoundingly achieved efficient, rapid, and on-site visual detection of UA in saliva, urine-simulants, and foods. Further, the NIFP-SM-based automatic analysis platform integrated with an intelligent RGB analysis device was manufactured and enabled accurate quantitative, low-cost, non-invasive/-enzymatic/-serodiagnostic, rapid, home-detecting for UA, eliminating the need for costly equipment and specialized personnel and thereby facilitating early-warning detection of abnormal UA-levels associated diseases.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 397-409"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Remediation and resource utilization of Cr(Ⅲ), Al(Ⅲ) and Zr(Ⅳ)-containing tannery effluent based on chitosan-carboxymethyl cellulose aerogel” [Journal of Bioresources and Bioproducts, 10 (2025) 77-91]","authors":"Shuang Liang ,&nbsp;Xuechuan Wang ,&nbsp;Chao Wei ,&nbsp;Long Xie ,&nbsp;Zhongming Song ,&nbsp;Xugang Dang","doi":"10.1016/j.jobab.2025.07.004","DOIUrl":"10.1016/j.jobab.2025.07.004","url":null,"abstract":"","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 425-426"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lateral resistance performance of wood-frame shear walls with wooden nail connections: Experimental and finite element analysis","authors":"Shuo Wang ,&nbsp;Jingkang Lin ,&nbsp;Suwan Dong ,&nbsp;Zhiyuan Chen ,&nbsp;Fanxu Kong ,&nbsp;Panpan Ma ,&nbsp;Feibin Wang ,&nbsp;Zeli Que","doi":"10.1016/j.jobab.2025.04.002","DOIUrl":"10.1016/j.jobab.2025.04.002","url":null,"abstract":"<div><div>Modern architecture and engineering increasingly favor timber structures due to their sustainability. Wooden nails, as eco-friendly alternatives to traditional metal connectors, offer promising potential for widespread adoption. This study analyzed the influence of various parameters on the shear performance of wooden nail connections through monotonic loading tests. Key factors examined included sheathing panel material (oriented strand board (OSB) and structural plywood (SP)), thickness (9.5 and 12 mm), as well as nail diameter (3.7 and 4.7 mm), spacing (50 and 100 mm), and cap configuration (with/without caps) on the mechanical behavior of the joints. Analyzing load-displacement curves and mechanical parameters (ultimate load, stiffness, ductility) reveals several key findings: nail cap design has minimal impact on shear performance compared to other factors; joints with SP sheathing panel material show significantly higher shear-bearing capacity than those with OSB. Stiffness and ductility vary across specimen groups, with group O9–4.7 (denoting OSB sheathing, 9.5 mm thickness, and 4.7 mm nail diameter) having the highest stiffness (1 332 N/mm) and group O12–4.7 (OSB sheathing, 12 mm thickness, and 4.7 mm nail diameter) showing superior ductility (3.47). Additionally, a comprehensive finite element (FE) simulation of full-size wood-frame shear walls using OpenSees software provides insights into the influence of sheathing panel form, material properties, and thickness on lateral resistance performance.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 410-424"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cellulose-based suture: State of art, challenge, and future outlook","authors":"Meiyan Wu ,&nbsp;Lei Ding ,&nbsp;Xiaoying Bai ,&nbsp;Yuxiang Cao ,&nbsp;Mehdi Rahmaninia ,&nbsp;Bing Li ,&nbsp;Bin Li","doi":"10.1016/j.jobab.2024.11.006","DOIUrl":"10.1016/j.jobab.2024.11.006","url":null,"abstract":"<div><div>Surgical sutures as the most widely used and high-value implanted materials are of vital importance in wound closure and healing. Among them, cellulose-based sutures with multifunctionality have been developed in recent decades, and are very promising to replace the fossil-based synthetic sutures. Therefore, this paper aims at covering the history and recent advances of cellulose-based suture, mainly including the materials used (e.g., natural cellulose, nanocellulose, and regenerated cellulose), fabrication methods and mechanism of wet spinning and the recently developed interfacial polyelectrolyte complexation spinning, as well as suture application performance (such as mechanical properties, cytocompatibility, biodegradability, absorbable properties, and antibacterial properties). More importantly, it summarizes all cellulose-based sutures, and then delves deep into the challenges and future outlook. Thus, this review provides an important reference for the development of high-end cellulose-based medical sutures.</div></div>","PeriodicalId":52344,"journal":{"name":"Journal of Bioresources and Bioproducts","volume":"10 3","pages":"Pages 295-309"},"PeriodicalIF":13.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144780116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}