Chronic Stress最新文献

{"title":"Translation and Validation of the Arabic International Adjustment Disorder Questionnaire Among Patients with Physical Illness and Their Families in Iraq.","authors":"Mustafa Al-Gburi, Mustafa A Waleed, Mark Shevlin, Ghaith Al-Gburi","doi":"10.1177/24705470251332801","DOIUrl":"https://doi.org/10.1177/24705470251332801","url":null,"abstract":"<p><strong>Background: </strong>The populations of middle- and low-income countries are exposed to many stressors, and these are associated with worse mental health. The ICD-11 includes a section \"Disorders specifically associated with stress\" and there are many validated measures for the assessment of stress-related disorders. However, there is no self-reported measure of ICD-11 adjustment disorder available for use in Arabic-speaking populations. This study aimed to translate and validate the Arabic version of the self-reported International Adjustment Disorder Questionnaire.</p><p><strong>Methods: </strong>Data was collected from Iraqi patients with physical illness and their families from October 6 to October 14, 2024, through a cross-sectional study conducted at Baghdad's Teaching Hospital and the Oncology Teaching Hospital. The R Environment for Statistical Programming was utilized for analysis.</p><p><strong>Results: </strong>Findings from confirmatory factor analysis were consistent with previous studies by identifying two strongly correlated factors (r = 0.72), representing the 'preoccupation' and 'failure to adapt' symptom clusters. These factors showed reliable scores (α = 0.695 and 0.814) and significant relations to depression and anxiety. To avoid multicollinearity, a total symptom scale can be used, based on similarly positive relations to psychological states and high reliability (α = 0.798).</p><p><strong>Conclusion: </strong>The Arabic translation demonstrates good psychometric properties and can be utilized in clinical and research settings.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470251332801"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Psychological Toll of War and Forced Displacement in Gaza: A Study on Anxiety, PTSD, and Depression.","authors":"Belal Aldabbour, Mariam El-Jamal, Amal Abuabada, Aseel Al-Dardasawi, Eman Abusedo, Huda Abu Daff, Hala Al-Saqqa, Doaa Abu Helal, Rawan Abu Radwan, Rola El-Hindawi, Mariam Hamada, Wafaa Abu Khader, Latefa Ali Dardas","doi":"10.1177/24705470251334943","DOIUrl":"https://doi.org/10.1177/24705470251334943","url":null,"abstract":"<p><strong>Background: </strong>Armed conflicts severely impact survivors psychologically, with effects tied to the trauma's intensity and widespread displacement. From October 2023 to January 2025, the Gaza Strip faced violent conflict, leading to major displacement and suffering. This study examines anxiety, PTSD, and depression among displaced adults from Gaza Strip.</p><p><strong>Methods: </strong>This cross-sectional study, conducted in November 2024, surveyed 952 displaced adults using the GAD-7, PCL-5, and PHQ-9 instruments and a convenience sampling method. A PTSD diagnosis required having a PCL-5 score ≥ 23 and fulfilling the DSM-5 criteria. The rates and severity of probable anxiety, PTSD, and depression were reported. Then, using SPSS, logistic regression models identified factors associated with each disorder, while multinomial regression models explored associations with the number of comorbidities.</p><p><strong>Results: </strong>The majority were unemployed (73.7%). Over half of the participants were displaced in camps (55.6%), while 40.4% lived in shelters. Nearly a fifth (20.3%) had lost a first-degree relative, 12.7% were injured, and 4.8% were detained by the military. Moderate or higher levels of anxiety and depression were reported by 79.3% and 84.5%, respectively. The rate of symptomatic PTSD was 67.8% when defined as meeting the DSM-5 criteria for PTSD and having a PCL-5 score ≥ 23, and 88.2% based on the latter criterion alone, while subthreshold PTSD was encountered in 18.1%. Also, 63.1% suffered significant symptoms of all three comorbidities. Significant predictors of anxiety included being female and having PTSD or depression. Significant predictors of PTSD included experiencing more frequent migrations, unemployment or working in the private sector, military detention, or having anxiety or depression. Significant predictors of depression included the death of a first-degree relative, military detention, torture, and having anxiety or PTSD. Additionally, having a higher number of migrations was significantly associated with having one, two, or three disorders compared to having \"no disorders,\" while those experiencing more forms of harm were significantly more likely to have all three disorders.</p><p><strong>Conclusions: </strong>The study found very high rates of psychiatric disorders among IDPs in Gaza and identified several risk factors contributing to those rates. Interventions must be prioritized to support society's long-term recovery.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470251334943"},"PeriodicalIF":0.0,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterizing the Prevalence of Psychiatric Conditions and Fear-Potentiated Startle Response in Civilians with a History of Trauma and Seizures.","authors":"Trinidi Prochaska, Helena Zeleke, Sean T Minton, Abigail Powers, Vasiliki Michopoulos, Jon T Willie, Daniel L Drane, Tanja Jovanovic, Sanne J H van Rooij","doi":"10.1177/24705470251321953","DOIUrl":"10.1177/24705470251321953","url":null,"abstract":"<p><strong>Background: </strong>Depression, posttraumatic stress disorder (PTSD), and suicidality are more prevalent among people with seizures, but few studies exist in low-resourced minoritized populations. Existing knowledge of the overlapping neurocircuitry between seizure activity in limbic regions (eg, medial temporal lobe epilepsy) and PTSD also suggests that people with seizure histories may exhibit PTSD-like alterations in their fear-potentiated startle (FPS) responses. However, this hypothesis has yet to be systematically tested. Here, we leveraged a large study on stress and trauma to evaluate the prevalence of psychiatric conditions and FPS responses in a low-resourced minoritized population of individuals with a history of seizures.</p><p><strong>Methods: </strong>Prevalence of self-reported PTSD symptoms, depression symptoms, suicidality, and history of suicide attempt were compared between people with and without self-reported seizures among a sample of 3012 predominantly racially marginalized and low-resourced civilians. We compared FPS responses in 13 people with a history of seizures to 13 rigorously matched seizure-free controls. FPS responses were measured using eyeblink data collected during a fear conditioning acoustic startle task.</p><p><strong>Results: </strong>Participants with a history of seizures showed significantly higher prevalence of depression symptoms, suicidality, history of suicide attempt, PTSD symptoms, and probable PTSD diagnosis than seizure-free controls, even after controlling for trauma load. Those with a history of seizures displayed heightened FPS responses and impaired fear discrimination which mimics that of PTSD.</p><p><strong>Conclusion: </strong>These data concur with prior literature on people with a history of seizure activity being at higher risk for psychiatric symptomatology. Additionally, this study provides novel insights on the psychophysiological fear response in trauma-exposed people with a history of seizures, which could inform the identification and treatment of psychiatric vulnerability in these individuals.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470251321953"},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association between Depression and Heart Attack: Examining Demographic and Behavioral Correlates in Tennessee.","authors":"Manik Ahuja, Achala Ghimire, Kajol Dahal, Esther Adebayo-Abikoye, Hadii Mamudu, Jeetendra Patel, McKenzie Dooley, Thiveya Sathiyaseelan, Chukwubuikem James Arize, Johanna Cimilluca, Nathaniel Keaton, Jennifer S Tinman, Rhonda Williams, Sana Hasan, Praveen Fernandopulle","doi":"10.1177/24705470251324781","DOIUrl":"10.1177/24705470251324781","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular diseases (CVD) and depression are growing global health concerns as heart attack and stroke solely account for around 85% of total CVD deaths and 280 million ie, while 3.4% of the world's population have depression. A bi-directional relationship exists between depression and heart disease: about one-fourth of heart disease patients experience depression, and those with depression have a higher risk of developing heart disease compared to the general population. This study aims to examine the association between depression and heart attack as a dependent variable, focusing on demographic and behavioral correlates of individuals in Tennessee.</p><p><strong>Methods: </strong>We performed a cross-sectional analysis using the 2022 Behavior Risk Factor Surveillance System (BRFSS) data for Tennessee (N = 5266). Our analytical approaches involved descriptive and multivariate analysis (logistic regression analysis) to assess the association between depression and heart attack in Tennessee. The primary dependent variable of interest was a self-reported lifetime heart attack and independent variables included self-reported lifetime depression, no exercise in the past 30 days, smoking status, race/ethnicity, gender, and age category.</p><p><strong>Results: </strong>A total of 7.5% (N = 731) of participants reported lifetime heart attack and 27.8% (N = 828) of participants reported depression. Depression was found to be significantly associated with higher odds of a heart attack (AOR = 1.36; 95% CI, 1.06, 1.73), p < 0.001). Similarly, no exercise in the past 30 days (AOR = 1.74; 95% CI, 1.39, 2.20, p < 0.001) was also associated with higher odds of a heart attack. Furthermore, low income, current smoking status, and race/ethnicity were not found to be significantly associated with heart attack in our study.</p><p><strong>Conclusion: </strong>This study reinforces the significant link between depression and heart attack while highlighting the complex interplay of demographic and behavioral factors influencing onset of cardiovascular diseases. The findings underscore the necessity for a comprehensive approach to cardiovascular health that integrates mental health considerations and addresses broader social determinants of health.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470251324781"},"PeriodicalIF":0.0,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Internal Validity and Reliability of the GAD-7 Test in Latin America.","authors":"Norman López, Breiner Morales-Asencio, Daniela Ripoll-Córdoba, Juancarlos Coronado-López, Nicole Caldichoury, César Quispe-Ayala, David Salazar, Yuliana Florez, Irina Flores-Poma, Cesar Castellanos, Jorge Herrera Pino, Indalecio Quispe-Rodríguez, Juan Cárdenas-Valverde, Karen Alcos-Flores, Elsa Muñoz-Romero, Kattia Cantillo-Pacheco, Paola Martínez-Sande, Loida Camargo, Ninoska Ocampo-Barba, Boris Zurita-Cueva, Juan Martínez, Cristian Araya, Cristian Romo, Regulo Antezana, Raúl Quincho-Apumayta, Pascual A Gargiulo","doi":"10.1177/24705470251315260","DOIUrl":"10.1177/24705470251315260","url":null,"abstract":"<p><p>Generalized anxiety has significantly increased in the general population during and after the COVID-19 pandemic, highlighting the need for rapid screening tools. In this context, the present study analyzed the psychometric properties and internal consistency of the Generalized Anxiety Disorder Scale (GAD-7) in healthcare workers and the general population in Latin America. A cross-sectional e-health study was conducted, surveying 11,279 Latin Americans online using snowball sampling. The sample included healthcare professionals, hospital populations, community members from various occupations, and university students from six countries (Argentina, Bolivia, Ecuador, Chile, Colombia, and Peru). Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA) were performed separately for each country. Additionally, the instrument's internal consistency was evaluated by calculating McDonald's W index and item-total correlations based on the final items. The EFA revealed a unidimensional structure comprising the seven items of the instrument, which explained between 62.8% and 66.1% of the variance (KMO = between .900 and .910; p < .000). The CFA confirmed adequate fit indices for each country. The omega index ranged from 0.85 (Peru: CI = 0.800-0.884) to 0.95 (Argentina-Bolivia: CI = 0.901-0.985), and item-total correlations were high, ranging from .642 to .869, demonstrating the instrument's reliability. In conclusion, the findings of this study indicate that the GAD-7 is a valid and reliable instrument for assessing generalized anxiety symptoms in the Latin American population.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470251315260"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Psychobiological Toll of Chronic Conflict: Posttraumatic Stress Symptoms, Emotion Dysregulation, and Physiology in a Conflict-Exposed Community in South Sudan.","authors":"Kellie Ann Lee, Sarah Beranbaum, Vivian Khedari-DePierro, Ellen H Yates, Ilya Yacevich, Anita Shankar, Condition Emmanuel Enosa, Tae Hwan Son, Greg J Norman, Wendy D'Andrea","doi":"10.1177/24705470251324783","DOIUrl":"10.1177/24705470251324783","url":null,"abstract":"<p><strong>Background: </strong>Mass conflict and related displacement in South Sudan has created a significant mental health need, however extant research on the impact of conflict is limited among South Sudanese people and has predominantly relied on Western-developed self report measures.</p><p><strong>Method: </strong>A total of 195 South Sudanese adults who work in both civil society and government leadership positions participated in a psychophysiological assessment of heart rate variability (HRV) and self-reported PTSD and emotion dysregulation symptoms to participation in the Trauma-Informed Community Empowerment (TICE) Framework, developed and implemented by the Global Trauma Project (GTP). We utilized measures of heart rate variability to determine parasympathetic activity, which may be associated with difficulties responding to stressors as well as long-term physical health morbidity and mortality.</p><p><strong>Results: </strong>Findings suggest pervasive difficulties in emotion regulation abilities among all participants and, consistent with the existing literature on PTSD in South Sudan, over a third of participants meet the clinical cut-off for PTSD. The majority of participants' physiological profiles indicate unexpected levels of parasympathetic nervous system activity given age and gender norms, demonstrating a sample with serious health risk. HRV did not correspond to self-reported PTSD symptoms, but did correlate with emotion dysregulation variables.</p><p><strong>Conclusions: </strong>These results demonstrate the feasibility and utility of using a multimethod approach to assessment in a community-based environment and highlight the psychophysiological burden of chronic socio-political strife.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470251324783"},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11898085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Criticality is Associated with Future Psychotherapy Response in Patients with Post-Traumatic Stress Disorder-A Pilot Study.","authors":"Remko van Lutterveld, Myrthe Sterk, Cristian Spitoni, Mitzy Kennis, Sanne J H van Rooij, Elbert Geuze","doi":"10.1177/24705470241311285","DOIUrl":"10.1177/24705470241311285","url":null,"abstract":"<p><strong>Background: </strong>Trauma-focused psychotherapy is treatment of choice for post-traumatic stress disorder (PTSD). However, about half of patients do not respond. Recently, there is increased interest in brain criticality, which assesses the phase transition between order and disorder in brain activity. Operating close to this borderline is theorized to facilitate optimal information processing. We studied if brain criticality is related to future response to treatment, hypothesizing that treatment responders' brains function closer to criticality.</p><p><strong>Methods: </strong>Functional magnetic resonance imaging resting-state scans were acquired from 46 male veterans with PTSD around the start of treatment. Psychotherapy consisted of trauma-focused cognitive behavioral therapy, eye movement desensitization and reprocessing, or a combination thereof. Treatment response was assessed using the Clinician-Administered PTSD Scale, and criticality was assessed using an Ising temperature approach for seven canonical brain networks (ie, the visual, somatomotor, dorsal attention, ventral attention, limbic, frontoparietal and default mode networks) to measure distance to criticality.</p><p><strong>Results: </strong>The brains of prospective treatment responders were closer to criticality than nonresponders (P = 0.017), while no significant interaction effect between group and brain network was observed (P = 0.486). In addition, average criticality across networks correlated with future treatment response (P = 0.028).</p><p><strong>Conclusion: </strong>These results show that the brains of prospective PTSD psychotherapy treatment responders operate closer to criticality than nonresponders, and this occurs across the entire brain instead of in separate canonical brain networks. These results suggest that effective psychotherapy is mediated by brains operating closer to criticality.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"9 ","pages":"24705470241311285"},"PeriodicalIF":0.0,"publicationDate":"2025-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11726532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Behavioral Therapy Reduces Unhelpful Thinking Among People with Musculoskeletal Symptoms: A Meta-Analysis.","authors":"Deven Niraj Patel, Rajeev Pathapati, Catherine Hand, Ashwin Varma, Sina Ramtin, David Ring","doi":"10.1177/24705470241304252","DOIUrl":"10.1177/24705470241304252","url":null,"abstract":"<p><strong>Background: </strong>Greater unhelpful thinking is associated with greater musculoskeletal discomfort and incapability. Cognitive-behavioral therapy (CBT) fosters healthy thinking to help alleviate symptoms.</p><p><strong>Questions: </strong>In a meta-analysis of randomized control trials (RCT) of CBT for unhelpful thinking among people with musculoskeletal symptoms, we asked: 1) Does CBT reduce unhelpful thinking and feelings of distress, and improve capability, in individuals with musculoskeletal symptoms? 2) Are outcomes affected by CBT delivery methods?</p><p><strong>Methods: </strong>Following QUOROM guidelines, we searched databases using keywords of pain catastrophizing, kinesiophobia, cognitive-behavioral therapy, musculoskeletal and variations. Inclusion criteria were RCT's testing CBT among people with musculoskeletal symptoms. Study quality was assessed with Cochrane Review of Bias 2. Meta-analysis of means and standard deviations was performed.</p><p><strong>Results: </strong>CBT led to modest reductions in catastrophic thinking (-0.44 CI: -0.76 to -0.12; <i>P</i> = .01, kinesiophobia (-0.60 CI: -1.07 to -0.14; <i>P</i> = .01) and anxiety symptoms (-0.23 CI: -0.36 to -0.09; <i>P</i> < .01) over six months compared to usual care. There were no improvements in levels capability (-0.28 CI: -0.56 to 0.01; <i>P</i> = .05). CBT led by mental health professionals reduced catastrophic thinking more than CBT led by other clinicians (QB Test = 4.73 <i>P</i> = .03). There were no differences between online and in-person sessions, group versus individual therapy, or surgical versus non-surgical interventions.</p><p><strong>Conclusion: </strong>The evidence that CBT delivered by various clinicians in various settings fosters healthier thinking in people presenting for care of musculoskeletal symptoms, supports comprehensive care of musculoskeletal illness. More research is needed to develop indications and interventions that also improve levels of capability. Level-I, meta-analysis of RCT's.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"8 ","pages":"24705470241304252"},"PeriodicalIF":0.0,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11660068/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Loss Cycle of Burnout Symptoms and Reduced Coping Self-Efficacy: A Latent Change Score Modelling Approach.","authors":"Liselotte M J Koning-Eikenhout, Roos Delahaij, Wim Kamphuis, Inge L Hulshof, Joris Van Ruysseveldt","doi":"10.1177/24705470241286948","DOIUrl":"10.1177/24705470241286948","url":null,"abstract":"<p><p>Police officers are frequently faced with chronic and acute stressors, such as excessive workload, organizational stressors and emotionally charged reports. This study aims to examine the relationship between a form of chronic strain (ie, burnout symptoms) and a resource (ie, coping self-efficacy) in a sample of Dutch police officers. Specifically, we aim to investigate the existence of a loss cycle of resources. We use Latent Change Score modeling to investigate the potential depletion or loss cycle of coping self-efficacy as a result of burnout symptoms in a sample of 95 police officers who completed a survey on three consecutive timepoints. The lag between the measurements was approximately one year. We found that, during both one-year intervals, within-person increases in burnout symptoms were related to within-person decreases in coping self-efficacy. Also, the results emphasize the buffering role of coping self-efficacy for burnout symptoms, as within-person decreases in coping self-efficacy during the first year were associated with within-person increases in burnout symptoms during the following year. Together, the results imply that a loss cycle of coping self-efficacy and burnout symptoms may occur. For this we used Latent Change Score modeling, which is a relatively new approach which provides researchers with the opportunity to analyse multi-wave longitudinal data while focusing on within-person changes over time. Practically, police organizations are advised to monitor personnel wellbeing and resources, to maintain and promote sustainable employability of police officers and to be able to timely provide individuals with interventions. Limitations discussed are the use of self-report measures and large intervals between the measurements. Finally, future directions of research are discussed that would circumvent the reported limitations, such as multiple wave with shorter lags and incorporating confounding factors that could affect coping self-efficacy.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"8 ","pages":"24705470241286948"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11462553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142395201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Genetic Variations in the FAAH rs324420 Polymorphism and its Interaction with CRHR1 rs110402 and CNR1 rs2180619 in Anxiety and- Trauma Related Symptoms After Military Deployment.","authors":"Nadia Leen, Antoin de Weijer, Marco Boks, Johanna Baas, Eric Vermetten, Elbert Geuze","doi":"10.1177/24705470241285828","DOIUrl":"10.1177/24705470241285828","url":null,"abstract":"<p><strong>Background: </strong>During military deployment, stress regulation is vital to protect against the development of anxiety and trauma-related symptoms. Brain endocannabinoids play an important role in stress regulation and previous research has shown that genetic variations in the FAAH rs324420 polymorphism demonstrate protective effects during stress. In addition, this polymorphism shows interactions with the CRHR1 and CNR1 polymorphisms on anxiety. The present study examines whether genetic variations of the FAAH, CRHR1 and CNR1 polymorphisms interact with the development of anxiety and trauma related symptoms in military veterans.</p><p><strong>Methods: </strong>Veterans (N = 949) who went on military deployment and experienced a stressful event were genotyped for FAAH rs324420, CRHR1 rs110402 and CNR1 rs2180619. Anxiety and trauma symptoms were measured pre-deployment and 6 months after deployment. Anxiety was measured with the anxiety subscale of the Symptom Checklist-90 (SCL-90) and trauma with the Self-Rating Inventory for PTSD (SRIP).</p><p><strong>Results: </strong>Covariance Pattern Models demonstrated no significant relation of genetic variations in FAAH rs324420 on anxiety and PTSD symptoms from pre-deployment to 6 months after military deployment. Additionally, we investigated interactions between the FAAH s324420, CRHR1 rs110402 and CNR1 rs2180619 polymorphisms. This also demonstrated no significant effects on anxiety and PTSD symptoms pre- to post deployment. However, the covariate of childhood trauma that was included in the models was significant in all these models.</p><p><strong>Conclusion: </strong>Genetic variations in FAAH rs324420 and its interactions with CRHR1 rs110402 and CNR1 rs2180619 are not related to the development of anxiety and trauma-related symptoms. The study however, indicates the importance of considering childhood trauma in the investigation of the effects of polymorphisms that are related to the endocannabinoid system on the development of anxiety and PTSD symptoms.</p>","PeriodicalId":52315,"journal":{"name":"Chronic Stress","volume":"8 ","pages":"24705470241285828"},"PeriodicalIF":0.0,"publicationDate":"2024-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11526235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}