Archives of Craniofacial Surgery最新文献

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Telepractice-based articulation therapy for children with cleft lip and palate: a clinical study using the Application for Articulation Therapy-Thai. 基于远程练习的儿童唇腭裂发音治疗:应用发音治疗的临床研究。
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2024.0092
Sasalaksamon Chanachai, Sumita Duangprasert, Benjamas Prathanee
{"title":"Telepractice-based articulation therapy for children with cleft lip and palate: a clinical study using the Application for Articulation Therapy-Thai.","authors":"Sasalaksamon Chanachai, Sumita Duangprasert, Benjamas Prathanee","doi":"10.7181/acfs.2024.0092","DOIUrl":"10.7181/acfs.2024.0092","url":null,"abstract":"<p><strong>Background: </strong>Compensatory articulation disorders are the most common issues among children with cleft palates with or without cleft lips (CP ± L). To improve their speech, these children typically require consistent, long-term speech therapy. During situations such as the COVID-19 pandemic or similar epidemics that necessitate social distancing, speech therapy becomes particularly challenging. Telemedicine or telepractice could serve as a strategy to facilitate speech therapy under these conditions. The aim of this study was to determine the effectiveness of telepractice using an application for articulation therapy in improving the percentage of correct consonants (PCC).</p><p><strong>Methods: </strong>Eighteen children with CP ± L (aged 5-13 years) were enrolled in a therapy program lasting 5 months. The Thai Speech Parameters for Patients with Cleft Palate in a Universal Reporting System test was administered to assess PCC before and after therapy. A total of 20 speech therapy sessions, comprising 15 telepractice sessions and five face-to-face sessions, were delivered using the Application for Articulation Therapy-Thai (AAT-T). The paired t-test was used to compare mean differences (MDs) in PCC scores before and after intervention.</p><p><strong>Results: </strong>Post-intervention analysis demonstrated significant increases in mean PCC scores at both word and sentence levels (word level: MD, 17.20; standard deviation [SD], 17.37; 95% confidence interval [CI], 8.56-25.83; sentence level: MD, 20.90; SD, 16.51; 95% CI, 12.69-29.11). These results indicate meaningful improvements in speech production accuracy.</p><p><strong>Conclusion: </strong>Telepractice using the AAT-T was an effective strategy for articulation therapy in children with CP ± L, particularly in situations requiring social distancing.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"102-108"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of upper airway and temporomandibular joint changes in growing patients with Class II Division 1 malocclusion, treated with the Twin Block appliance: a retrospective cone-beam computed tomography study. 使用Twin Block矫治器治疗II类1类错牙合成长期患者上呼吸道和颞下颌关节变化的评估:回顾性锥束计算机断层扫描研究
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2024.0093
Ioannis Anagnostopoulos, Snigdha Pattanaik, Ahmed Zaky, Ahmed El-Motayam, Shishir Ram Shetty, Mais M Sadek
{"title":"Assessment of upper airway and temporomandibular joint changes in growing patients with Class II Division 1 malocclusion, treated with the Twin Block appliance: a retrospective cone-beam computed tomography study.","authors":"Ioannis Anagnostopoulos, Snigdha Pattanaik, Ahmed Zaky, Ahmed El-Motayam, Shishir Ram Shetty, Mais M Sadek","doi":"10.7181/acfs.2024.0093","DOIUrl":"10.7181/acfs.2024.0093","url":null,"abstract":"<p><strong>Background: </strong>The Twin Block (TWB) appliance is widely employed for treating Class II malocclusion in children and adolescents. This study aimed to evaluate the three-dimensional treatment effects of the TWB on the upper airway and temporomandibular joint (TMJ), and to investigate the association between airway changes and TMJ alterations.</p><p><strong>Methods: </strong>This retrospective study examined 24 cone-beam computed tomography (CBCT) scans from 12 patients (mean age, 12.30 ± 1.24 years) diagnosed with Class II Division 1 malocclusion and treated with the TWB appliance. CBCT scans were acquired both at pretreatment (T0) and posttreatment (T1). Romexis 6.2.1 imaging software was used to assess changes in the upper airway and TMJ. The paired t-test was used to compare the pretreatment and posttreatment measurements, while Pearson correlation coefficient analysis evaluated the relationship between the upper airway and TMJ measurements.</p><p><strong>Results: </strong>A statistically significant increase was observed in the upper airway volume, condylar volume, and condylar dimensions after treatment. No significant correlation was detected between the upper airway and TMJ measurements at T0, T1, or in the net changes (T1-T0) during TWB therapy.</p><p><strong>Conclusion: </strong>Growing patients treated with the TWB appliance demonstrated a statistically significant increase in upper airway volume. In addition, there was a significant increase in condylar volume, width, and length, with the condyle repositioned more anteriorly within the glenoid fossa. However, no statistically significant correlation was found between the TMJ and upper airway measurements.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"92-101"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of jaw fractures in motorcycle accidents: a systematic review. 摩托车事故中颌骨骨折的分析:系统回顾。
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2025.0008
Andi Muhammad Arif, Andi Tajrin, Nurwahida
{"title":"Analysis of jaw fractures in motorcycle accidents: a systematic review.","authors":"Andi Muhammad Arif, Andi Tajrin, Nurwahida","doi":"10.7181/acfs.2025.0008","DOIUrl":"10.7181/acfs.2025.0008","url":null,"abstract":"<p><strong>Background: </strong>The mandible and maxilla are the most robust facial bones, protecting the facial skull. Fractures of these bones rank among the most common facial injuries sustained in motor vehicle accidents due to the exposed location of the face. Such injuries can have serious health consequences, from functional impairment to death.</p><p><strong>Methods: </strong>The review adhered to the PRISMA Guidelines. Conducted across four electronic databases: Web of Science, PubMed, Embase, and Google Scholar. Keywords were selected based on a search strategy structured around the Population, Intervention, Comparison, and Outcome framework. Risk of bias was assessed using the Scottish Intercollegiate Guidelines Network criteria.</p><p><strong>Results: </strong>The literature search yielded 42 articles published in the last 5 years (2019-2024). After the predefined inclusion and exclusion criteria were applied, six articles met the eligibility criteria. Data from these studies, along with their bias assessments, were summarized in tabular format.</p><p><strong>Conclusion: </strong>The reported incidence of maxillary and mandibular fractures varies across studies. The summarized analysis in this article indicates various fracture patterns. This review also emphasizes the role of trauma severity indices-essential tools for prognostic evaluation, treatment planning, and cost of injury assessment in trauma patients-along with their applications in situations involving triage and multidisciplinary scientific approaches.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"85-91"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduction of a malunited bilateral parasymphysis fracture using a Carrol-Girard screw: a case report. 卡罗尔-吉拉德螺钉复位双侧副骨关节不愈合骨折1例。
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2026.0006
Trishala Annamalai Rajan, Elavenil Panneerselvam, Shri Krishna Prasanth Balasubramanian, Sasikala Balasubramanian, V B Krishna Kumar Raja
{"title":"Reduction of a malunited bilateral parasymphysis fracture using a Carrol-Girard screw: a case report.","authors":"Trishala Annamalai Rajan, Elavenil Panneerselvam, Shri Krishna Prasanth Balasubramanian, Sasikala Balasubramanian, V B Krishna Kumar Raja","doi":"10.7181/acfs.2026.0006","DOIUrl":"10.7181/acfs.2026.0006","url":null,"abstract":"<p><p>Restoration of skeletal form and occlusion in bilateral parasymphysis fractures is technically demanding due to the fragmented mandible and the unfavorable muscular biodynamics. Accurate reduction is crucial for restoring the sagittal projection and transverse dimension of the anterior mandible. This case report describes a straightforward technique that facilitates precise anatomical reduction and stabilization during fixation of the central fragment using a Carroll-Girard screw.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"129-132"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and treatment of verrucous carcinoma of the lip: a case report. 唇疣状癌的诊断与治疗1例。
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2024.0058
Hye Mi Lee, Eun Jung Jang, Young Cheon Na
{"title":"Diagnosis and treatment of verrucous carcinoma of the lip: a case report.","authors":"Hye Mi Lee, Eun Jung Jang, Young Cheon Na","doi":"10.7181/acfs.2024.0058","DOIUrl":"10.7181/acfs.2024.0058","url":null,"abstract":"<p><p>Verrucous carcinoma, a variant of squamous cell carcinoma, is notable for its lower aggressiveness; however, it presents considerable diagnostic challenges. This tumor is often misdiagnosed, leading to delays in treatment. We describe the case of an 84-year-old woman with verrucous carcinoma presenting as a warty lesion on the lip. The initial biopsy established a diagnosis of verrucous carcinoma, after which wedge resection with a lateral advancement flap was performed. Although the operation was successful, tumor recurrence was observed at the surgical site within several weeks, and a subsequent biopsy identified squamous cell carcinoma. Further surgical intervention proved effective, with no recurrence observed 6 months after treatment. This case emphasizes the importance of precise diagnosis and vigilant management in verrucous carcinoma, highlighting the need for clinicians and pathologists to recognize atypical progression, including hybrid variants. Further research is needed to refine diagnostic criteria and therapeutic strategies for this distinctive and unpredictable malignancy.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"124-128"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstruction of large facial defects using three or more local flaps. 使用三个或更多局部皮瓣重建大面积面部缺损。
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2024.0045
Min Hak Lee, Changryul Claud Yi, Hoon Soo Kim, Yong Chan Bae
{"title":"Reconstruction of large facial defects using three or more local flaps.","authors":"Min Hak Lee, Changryul Claud Yi, Hoon Soo Kim, Yong Chan Bae","doi":"10.7181/acfs.2024.0045","DOIUrl":"10.7181/acfs.2024.0045","url":null,"abstract":"<p><strong>Background: </strong>Free flaps, skin grafts, and local flaps are viable options for reconstructing large facial defects. When skin grafts, free flaps, or a single local flap are either not feasible or unlikely to yield satisfactory results, reconstruction can be performed using three or more local flaps. To evaluate the effectiveness of this surgical technique, this study analyzed the outcomes of reconstructions that utilized three or more local flaps.</p><p><strong>Methods: </strong>This study included 10 patients who underwent facial reconstruction with three or more flaps following Mohs micrographic surgery (MMS) for skin cancer from 2016 to 2021. We investigated the types of flaps used, complications, and the recurrence rates of skin cancer. Patient satisfaction regarding color, contour, and scar was assessed through a questionnaire.</p><p><strong>Results: </strong>Of the 10 patients, nine underwent reconstruction with three flaps, while one patient required four flaps. There were no major complications such as flap loss. Partial necrosis occurred in one patient but was successfully managed with conservative treatment. There were no recurrences of the skin cancer that caused the initial defect, and overall patient satisfaction was high. Patients expressed high satisfaction with color, but lower satisfaction with contour and scar.</p><p><strong>Conclusion: </strong>For large facial defects where free flaps or skin grafts would yield aesthetically or functionally inferior results, and reconstruction with a single flap is challenging, the application of three or more flaps has achieved good surgical outcomes. Utilizing three or more flaps can be considered a clinically useful method for reconstructing large facial defects.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"109-114"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of orthognathic surgery on emotional expression and smile aesthetics in Chinese patients as measured by FaceReader: a before-and-after study. 脸谱阅读器测量的正颌手术对中国患者情绪表达和微笑美学的影响:前后对比研究
Archives of Craniofacial Surgery Pub Date : 2025-06-01 Epub Date: 2025-06-20 DOI: 10.7181/acfs.2025.0007
Thanapoom Boonipat, Jason Lin, Sai Cherukuri, Zhi Yang Ng, Eugene Yu-Jen Chen, Chuan-Fong Yao
{"title":"Impact of orthognathic surgery on emotional expression and smile aesthetics in Chinese patients as measured by FaceReader: a before-and-after study.","authors":"Thanapoom Boonipat, Jason Lin, Sai Cherukuri, Zhi Yang Ng, Eugene Yu-Jen Chen, Chuan-Fong Yao","doi":"10.7181/acfs.2025.0007","DOIUrl":"10.7181/acfs.2025.0007","url":null,"abstract":"<p><strong>Background: </strong>The attractiveness of a person's smile is influenced by several factors, including gingival display, incisor show, and facial asymmetries. Malocclusion has long been recognized as having a significant negative impact on smile aesthetics. Addressing dentofacial deformities is a major treatment goal in orthodontic and orthognathic interventions, aiming to improve both functional and aesthetic outcomes. We sought to quantify and assess the impact of orthognathic surgery on a patient's expression of happiness within their smile, thereby addressing the current research gap in this highly subjective field.</p><p><strong>Methods: </strong>We utilized FaceReader, a commercially available and previously validated artificial intelligence (AI) system, to analyze preoperative and postoperative facial photographs of 216 Chinese patients who underwent orthognathic surgery between January 1, 2021, and December 31, 2022. The AI software measures seven cardinal emotions and associated facial action units, providing an objective evaluation of emotional outcomes.</p><p><strong>Results: </strong>Our findings indicated a significant postoperative increase in patients' expression of \"happiness\" while smiling, accompanied by a concurrent decrease in their estimated age. Patients with insufficient incisor show and open bite exhibited notable improvements in emotional expression, while those with a gummy smile showed no significant change. Additionally, stratification based on malocclusion classification (class I, II, III) revealed consistent improvements in emotional outcome scores among class II and III patients.</p><p><strong>Conclusion: </strong>Our findings underscore the potential of AI in providing objective insights into emotional changes following orthognathic surgery.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 3","pages":"115-123"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12235305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In-house dental lab-based cranial prosthesis fabrication: a technical note. 基于内部牙科实验室的颅骨假体制作:技术说明。
Archives of Craniofacial Surgery Pub Date : 2025-04-01 Epub Date: 2024-09-09 DOI: 10.7181/acfs.2024.00185
Gunjan Chouksey, Babu Lal, Prateek Shakti, Vineeta Yadav, Jitendra Kumar, Zenish R Bhatti
{"title":"In-house dental lab-based cranial prosthesis fabrication: a technical note.","authors":"Gunjan Chouksey, Babu Lal, Prateek Shakti, Vineeta Yadav, Jitendra Kumar, Zenish R Bhatti","doi":"10.7181/acfs.2024.00185","DOIUrl":"10.7181/acfs.2024.00185","url":null,"abstract":"<p><p>Cranial prostheses are frequently required for patients with cranial defects secondary to trauma, decompressive craniectomy, or other pathologies. When the resected or craniotomized bone cannot be reused, cranioplasty with artificial materials offers both aesthetic and protective benefits. However, high-end custom-made options, like polyether ether ketone or titanium prostheses, are expensive and not widely available. Heat-cured polymethyl methacrylate (PMMA) prostheses are generally preferred over their cold-cured counterparts. In-house dental laboratories can provide a cost-effective and practical solution by employing a lost-wax technique akin to denture fabrication, utilizing a three-dimensional printed custom open mold. Fabricating large heatcured PMMA cranioplasts presents certain challenges, such as the need for large flasks and potential porosity. These can be overcome by using a large stainless steel container (a tiffin box) and M-Seal epoxy to ensure an airtight curing process. This method can be easily adopted by standard dental laboratories. At our center, four patients have successfully fitted with cranioplasty prostheses produced using this technique. Even though the patients are outside of the scope of this technical note all of them indicated high satisfaction, and no complications were reported. This straightforward approach demonstrates that in-house, heat-cured PMMA cranioplasts can represent a viable, cost-effective option for cranial reconstruction.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":" ","pages":"80-83"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061782/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142156636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atypical elastofibroma of the philtrum mimicking rosacea: a case report and literature review. 仿酒糟鼻的中性腺非典型弹性纤维瘤1例报告及文献复习。
Archives of Craniofacial Surgery Pub Date : 2025-04-01 Epub Date: 2025-04-20 DOI: 10.7181/acfs.2026.0002
Minwoo Park, Sug Won Kim, Chae Eun Yang, Jiye Kim
{"title":"Atypical elastofibroma of the philtrum mimicking rosacea: a case report and literature review.","authors":"Minwoo Park, Sug Won Kim, Chae Eun Yang, Jiye Kim","doi":"10.7181/acfs.2026.0002","DOIUrl":"https://doi.org/10.7181/acfs.2026.0002","url":null,"abstract":"<p><p>Elastofibroma is a rare soft tissue tumor that most commonly occurs in the subscapular region. It has also been reported in several other anatomical locations. To our knowledge, no previous reports have described elastofibromas in the anterior aspect of the face. A 36-year-old man with intellectual disability was referred to our department for the evaluation of a painless multinodular lesion on the philtrum. The lesion was initially misdiagnosed as a dermatologic condition by the department of dermatology and was treated accordingly, however, it worsened, prompting referral to our department. We performed a surgical excision of the lesion and reconstructed the resulting skin defect with a skin graft. Histopathological examination confirmed the diagnosis of elastofibroma. This case underscores the importance of including elastofibroma in the differential diagnosis of facial neoplasms, particularly when the presentation is phymatous.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 2","pages":"76-79"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidisciplinary approach for medication-related osteonecrosis of the jaws: a case report and literature review. 多学科方法治疗颌骨药物相关性骨坏死:1例报告及文献复习。
Archives of Craniofacial Surgery Pub Date : 2025-04-01 Epub Date: 2025-04-20 DOI: 10.7181/acfs.2024.0091
Senthilkumar Annamalai, Arunkumar Kamalakaran, Balaji Jayaraman, Anushya Selvakumar, Harish Suresh Kulkarni
{"title":"Multidisciplinary approach for medication-related osteonecrosis of the jaws: a case report and literature review.","authors":"Senthilkumar Annamalai, Arunkumar Kamalakaran, Balaji Jayaraman, Anushya Selvakumar, Harish Suresh Kulkarni","doi":"10.7181/acfs.2024.0091","DOIUrl":"https://doi.org/10.7181/acfs.2024.0091","url":null,"abstract":"<p><p>Medication-related osteonecrosis of the jaw (MRONJ) is a relatively rare but well-documented complication of bisphosphonate therapy. Bisphosphonates are prescribed to millions of patients for the treatment of osteoporosis, Paget's disease, multiple myeloma, bone metastases, and other bone-related conditions. These drugs inhibit bone resorption by binding to hydroxyapatite, particularly in areas of active resorption, thereby preventing osteoclasts from attaching to the bone. Long-term bisphosphonate therapy is considered a primary risk factor for MRONJ. Bisphosphonate-induced osteonecrosis typically manifests as exposed alveolar bone, which may occur spontaneously or following invasive dental procedures such as extractions, apicectomies, or implant placement. This case report describes a female who developed osteonecrosis in the maxilla and mandible after undergoing bisphosphonate therapy for multiple myeloma and subsequent tooth extractions.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"26 2","pages":"70-75"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12061783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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