Yoon Kyu Chung, Min-Seok Kim, Jin Yong Shin, Nae-Ho Lee, Ae Ri An, Si-Gyun Roh
{"title":"Malignant melanoma associated with a plaque-type blue nevus of the cheek: a case report.","authors":"Yoon Kyu Chung, Min-Seok Kim, Jin Yong Shin, Nae-Ho Lee, Ae Ri An, Si-Gyun Roh","doi":"10.7181/acfs.2023.00024","DOIUrl":"10.7181/acfs.2023.00024","url":null,"abstract":"<p><p>Blue nevi, which are characterized by collections of pigment-producing melanocytes in the dermis, have a variety of clinicopathological characteristics. Plaque-type blue nevus (PTBN) is a variant of blue nevi. PTBN presents at birth or arises in early childhood, and it shows a combination of the features found in common blue nevus and cellular blue nevus. It is typically found on the dorsal surface of the hands and feet or on the head and neck, and it is usually benign and stable over time. However, reports have occasionally described malignant melanomas developing in or associated with a PTBN. Malignant blue nevi are most commonly found on the scalp. We report the case of an 88-year-old woman with a malignant melanoma associated with a PTBN of the cheek.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 2","pages":"78-82"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/83/fe/acfs-2023-00024.PMC10165239.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9431264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jong Hyun Park, Dong Hee Kang, Hong Bae Jeon, Hyonsurk Kim
{"title":"Orbital wall restoration with primary bone fragments in complex orbital fractures.","authors":"Jong Hyun Park, Dong Hee Kang, Hong Bae Jeon, Hyonsurk Kim","doi":"10.7181/acfs.2022.01116","DOIUrl":"https://doi.org/10.7181/acfs.2022.01116","url":null,"abstract":"<p><strong>Background: </strong>Complex orbital fractures are impure orbital fractures because they involve the orbital walls and mid-facial bones. The author reported an orbital wall restoration technique in which the primary orbital wall fragments were restored to their prior position in complex orbital fractures in 2020. As a follow-up to a previous preliminary study, this study retrospectively reviewed the surgical results of complex orbital wall fractures over a 4-year period and compared the surgical outcomes by dividing them into groups with and without balloon restoration.</p><p><strong>Methods: </strong>Data of 939 patients with facial bone fractures between August 2018 and August 2022 were reviewed. Of these, 154 had complex orbital fractures. Among them, 44 and 110 underwent reduction with and without the balloon technique respectively. Pre- and postoperative Naugle exophthalmometer (Good-Lite Co.) scales were evaluated. The orbital volume and orbital volume ratio were calculated from preoperative and 6 months postoperative computed tomography images.</p><p><strong>Results: </strong>Among 154 patients with complex orbital fractures, 44 patients underwent restoration with the balloon technique, and 110 patients underwent restoration without it. The Naugle scale did not differ significantly between the two groups, but the orbital volume ratio significantly decreased by 3.32% and 2.39% in groups with and without the balloon technique and the difference in OVR was significantly greater in patients in the balloon restoration group compared with the control group. Postoperative balloon rupture occurred in six out of 44 cases (13.64%). None of the six patients with balloon rupture showed significant enophthalmos at 6 months of follow-up.</p><p><strong>Conclusion: </strong>The balloon rupture rate was 13.64% (6/44 cases) with marginal screw fixation, blunt screws, and extra protection with a resorbable foam dressing. Furthermore, we restored the orbital wall with primary orbital fragments using balloon support in complex orbital wall fractures.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 2","pages":"52-58"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/48/ed/acfs-2022-01116.PMC10165238.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9437964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Young Jun Kim, Min Hyub Choi, Ji Seon Cheon, Woo Young Choi
{"title":"Periorbital cutaneous angiomyolipoma: a case report.","authors":"Young Jun Kim, Min Hyub Choi, Ji Seon Cheon, Woo Young Choi","doi":"10.7181/acfs.2022.01088","DOIUrl":"https://doi.org/10.7181/acfs.2022.01088","url":null,"abstract":"<p><p>Angiomyolipomas are usually found in the kidneys of patients with tuberous sclerosis. They occur less frequently in organs such as the liver, the oral cavity, the nasal cavity, the heart, the large intestines, and the lungs. Angiomyolipomas of the skin are extremely rare, and cutaneous angiomyolipomas generally occur on the elbow, the ends of digits, the ear, and the glabella. Herein we present a rare case of angiomyolipoma occurring on the face-specifically, the right upper eyelid. We propose that upper eyelid angiomyolipoma is a hamartomatous, rather than neoplastic, lesion. Although angiomyolipoma in the periocular area is rare, it should be considered in the differential diagnosis of clinically benign masses. and regular follow-up is warranted.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 2","pages":"83-86"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/82/9a/acfs-2022-01088.PMC10165237.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9437966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Kyu-Hyung Park, Se Yeon Lee, Jong-Ho Kim, Baek-Kyu Kim
{"title":"Long-term outcomes after core extirpation of fibrous dysplasia of the zygomaticomaxillary region.","authors":"Joseph Kyu-Hyung Park, Se Yeon Lee, Jong-Ho Kim, Baek-Kyu Kim","doi":"10.7181/acfs.2023.00038","DOIUrl":"https://doi.org/10.7181/acfs.2023.00038","url":null,"abstract":"<p><strong>Background: </strong>Fibrous dysplasia (FD) is a localized bone disorder in which fibro-osseous tissue replaces the normal bone structure. Patients with craniofacial FD often present with gradual swelling, deformity, and compromised vision or hearing. We previously introduced \"the core extirpation method,\" a novel surgical technique that is minimally invasive like traditional bone shaving but has longer-lasting effects. This study presents the long-term outcomes of our core extirpation method.</p><p><strong>Methods: </strong>We conducted a retrospective analysis of patients who underwent core extirpation for FD of the zygomaticomaxillary region from 2012 through 2021. Computed tomography (CT) scans were performed 6 to 12 months before the operation, immediately before and after the operation, and during follow-up visits. We performed all operations using the upper gingivobuccal approach, and we extirpated the core of the lesion while preserving the cortical structures of the zygoma and the maxilla to maintain symmetrical facial contour.</p><p><strong>Results: </strong>In 12 patients with lesions in the growth phase, anteroposterior/mediolateral (AP/ML) length discrepancies and the volume increased between preoperative and immediate postoperative CT scans. All patients' immediate postoperative AP/ML discrepancies were stable up to 12-17 months postoperatively. Postoperative volume showed continuous lesion growth; the median volume growth rate was 0.61 cc per month.</p><p><strong>Conclusion: </strong>In this article, we present our experiences managing FD using the minimally invasive core extirpation technique, which entails small expected blood loss and can be performed as day surgery. It provides similar cosmetic outcomes as traditional bone shaving but with longer-lasting results. Although there are some limitations with the study's retrospective nature and small sample size, our 4-year follow-up results show promising results of the core extirpation method in well-indicated patients.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 2","pages":"59-65"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b0/03/acfs-2023-00038.PMC10165236.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9431266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current concepts of craniofacial fibrous dysplasia: pathophysiology and treatment.","authors":"Dong Yeon Kim","doi":"10.7181/acfs.2023.00101","DOIUrl":"https://doi.org/10.7181/acfs.2023.00101","url":null,"abstract":"<p><p>Fibrous dysplasia is an uncommon genetic disorder in which bone is replaced by immature bone and fibrous tissue, manifesting as slowgrowing lesions. Sporadic post-zygotic activating mutations in GNAS gene result in dysregulated GαS-protein signaling and elevation of cyclic adenosine monophosphate in affected tissues. This condition has a broad clinical spectrum, ranging from insignificant solitary lesions to severe disease. The craniofacial area is the most common site of fibrous dysplasia, and nine out of 10 patients with fibrous dysplasia affecting the craniofacial bones present before the age of 5. Surgery is the mainstay of treatment, but the technique varies according to the location and severity of the lesion and associated symptoms. The timing and indications of surgery should be carefully chosen with multidisciplinary consultations and a patient-specific approach.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 2","pages":"41-51"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a4/0e/acfs-2023-00101.PMC10165234.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9437963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoon Soo Kim, Jeong Jin Park, Hyung Suk Yi, Jin Hyung Park, Hong Il Kim
{"title":"Is the retroauricular region a suitable donor site for full-thickness skin grafting in the era of mask wearing?","authors":"Yoon Soo Kim, Jeong Jin Park, Hyung Suk Yi, Jin Hyung Park, Hong Il Kim","doi":"10.7181/acfs.2023.00164","DOIUrl":"10.7181/acfs.2023.00164","url":null,"abstract":"<p><strong>Background: </strong>During the coronavirus disease 2019 (COVID-19) pandemic, the everyday use of face masks massively increased to prevent the spread of infection. Many people complain of ear pain and erosion when wearing a mask for extended periods of time. If prolonged mask usage is uncomfortable for ordinary people, a question arises-how much more inconvenient must mask wearing be for patients with a full-thickness skin graft (FTSG) donor site in the retroauricular region? Herein, we evaluated complications related to face mask use in 27 patients with a retroauricular FTSG donor site, with the goal of clarifying whether the retroauricular region is still an appropriate FTSG donor site in the context of the COVID-19 pandemic.</p><p><strong>Methods: </strong>Complications in 27 patients treated by FTSGs harvested from the retroauricular region from 2019 to 2021 were investigated. A questionnaire comparing the normal and the operated sides was administered. Pain, itching, soreness, deformity, and symmetry were further investigated.</p><p><strong>Results: </strong>Pain and itching were the only observed complications. The operated side was slightly more painful than the normal side in four patients (14.8%), and four patients (14.8%) reported itching on the operated side. However, all patients who experienced complications stated that the pain or itching did not interfere with mask wearing. Most symptomatic patients were older than 60 years of age (23.8%, p=0.185) and wore masks for longer periods of time (28.5%, p=0.326).</p><p><strong>Conclusion: </strong>Few retroauricular donor site-related complications occurred, and none of these complications caused inconvenience in daily life. Therefore, in the COVID-19 pandemic, the use of the retroauricular region as an FTSG donor site remains appropriate.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 2","pages":"66-72"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/ab/acfs-2023-00164.PMC10165235.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9431268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Ho Choi, Seung Yeon Choi, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee
{"title":"Seroma prevention with topical Abnobaviscum sclerotherapy following excision of giant cervical lipoma","authors":"Jun Ho Choi, Seung Yeon Choi, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee","doi":"10.7181/2023.00017","DOIUrl":"https://doi.org/10.7181/2023.00017","url":null,"abstract":"Background: Lipomas are common benign tumors of mesenchymal origin that are composed of mature adipocytes. Giant lipomas have a diameter ≥ 10 cm in one or more dimensions or weigh at least 1,000 g. The surgical excision of a giant lipoma requires extensive dissection, increasing the risk of a seroma, which can cause surgical site complications such as wound infection and necrosis. Sclerotherapy with Abnobaviscum (<i>Viscum album</i> extract) is a relatively new technique used to reduce malignant pleural effusion. In this study, we evaluated the effectiveness of prophylactic sclerotherapy using Abnobaviscum to decrease seroma after giant lipoma excision.Methods: We conducted a retrospective medical record review of patients who underwent surgical excision for giant lipoma of the neck from January 2019 to December 2022. Sclerotherapy was performed on the first postoperative day in patients who consented to the procedure, and Abnobaviscum was instilled through the existing Hemovac drain. We compared the clinical course between those who underwent postoperative sclerotherapy and those who did not.Results: Among the 30 patients who underwent giant lipoma excision, we applied sclerotherapy with Abnobaviscum to 15 patients. The average time from surgery to Hemovac removal was statistically shorter in patients who underwent sclerotherapy (<i>p</i>= 0.004). Furthermore, seroma formation was significantly reduced in patients receiving sclerotherapy (<i>p</i>= 0.003).Conclusion: In patients undergoing giant lipoma excision, sclerotherapy using Abnobaviscum helps reduce postoperative seroma formation during the initial postoperative period. It can be an excellent method to reduce complications related to seroma and attenuate patients’ postoperative burden.Abbreviations: BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; NSAIDs, nonsteroidal anti-inflammatory drugs; POD, postoperative day","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"184 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134967703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Ho Choi, Sang Seong Oh, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee
{"title":"Residual foreign body inflammation caused by a lumber beam penetrating the facial region: a case report.","authors":"Jun Ho Choi, Sang Seong Oh, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee","doi":"10.7181/acfs.2022.01018","DOIUrl":"https://doi.org/10.7181/acfs.2022.01018","url":null,"abstract":"<p><p>Penetrating wounds to the face are cosmetically devastating and can be life-threatening. If the foreign body causing the penetrating wound is a piece of wood, small remnants might be left behind after the initial treatment. A 33-year-old male patient presented to the emergency center after a piece of lumber pierced his face as a passenger in a traffic accident. The patient's vital signs were stable, and emergency surgery was performed to remove the foreign body and repair the soft tissue. No noteworthy complications were seen after open reduction and internal fixation of the facial bone fractures. Seven months after the accident, the patient underwent scar revision along with full-thickness skin grafting for post-traumatic scars. After the surgery, pus-like discharge which was not previously present was observed, and the graft did not take well. A residual foreign body, which was the cause of graft failure, was found on computed tomography and the remaining foreign body was removed through revision surgery. The patient is receiving outpatient follow-up without any complications 6 months after surgery. This case demonstrates the importance of performing a careful evaluation to avoid missing a residual foreign body, especially if it is of wooden nature.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 1","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/79/97/acfs-2022-01018.PMC10009212.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9118063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jun Ho Choi, Seung Yeon Choi, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee
{"title":"Seroma prevention with topical Abnobaviscum sclerotherapy following excision of giant cervical lipoma.","authors":"Jun Ho Choi, Seung Yeon Choi, Jae Ha Hwang, Kwang Seog Kim, Sam Yong Lee","doi":"10.7181/acfs.2023.00017","DOIUrl":"https://doi.org/10.7181/acfs.2023.00017","url":null,"abstract":"<p><strong>Background: </strong>Lipomas are common benign tumors of mesenchymal origin that are composed of mature adipocytes. Giant lipomas have a diameter ≥ 10 cm in one or more dimensions or weigh at least 1,000 g. The surgical excision of a giant lipoma requires extensive dissection, increasing the risk of a seroma, which can cause surgical site complications such as wound infection and necrosis. Sclerotherapy with Abnobaviscum (Viscum album extract) is a relatively new technique used to reduce malignant pleural effusion. In this study, we evaluated the effectiveness of prophylactic sclerotherapy using Abnobaviscum to decrease seroma after giant lipoma excision.</p><p><strong>Methods: </strong>We conducted a retrospective medical record review of patients who underwent surgical excision for giant lipoma of the neck from January 2019 to December 2022. Sclerotherapy was performed on the first postoperative day in patients who consented to the procedure, and Abnobaviscum was instilled through the existing Hemovac drain. We compared the clinical course between those who underwent postoperative sclerotherapy and those who did not.</p><p><strong>Results: </strong>Among the 30 patients who underwent giant lipoma excision, we applied sclerotherapy with Abnobaviscum to 15 patients. The average time from surgery to Hemovac removal was statistically shorter in patients who underwent sclerotherapy (p= 0.004). Furthermore, seroma formation was significantly reduced in patients receiving sclerotherapy (p= 0.003).</p><p><strong>Conclusion: </strong>In patients undergoing giant lipoma excision, sclerotherapy using Abnobaviscum helps reduce postoperative seroma formation during the initial postoperative period. It can be an excellent method to reduce complications related to seroma and attenuate patients' postoperative burden.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5b/a5/acfs-2023-00017.PMC10009210.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9113355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jin Myung Yoon, Tae Jun Park, Sae Hwi Ki, Min Ki Hong
{"title":"Unusual anomaly of the radial artery encountered during the elevation of a radial forearm free flap: a case report.","authors":"Jin Myung Yoon, Tae Jun Park, Sae Hwi Ki, Min Ki Hong","doi":"10.7181/acfs.2022.01032","DOIUrl":"https://doi.org/10.7181/acfs.2022.01032","url":null,"abstract":"<p><p>The radial forearm free flap (RFFF) has become popular for head and neck reconstructions. Owing to a constant anatomy the RFFF is relatively easy to dissect. Nevertheless, anatomical variations of the radial artery have been reported. Some variations could affect the survival of the flap. This paper reports an unusual anomaly of the radial artery where the radial artery was not located between the brachioradialis (BR) and flexor carpi radialis. The radial artery was observed above the BR and on the radial side of the BR. The survival of the elevated flap was deemed questionable because it had only few perforators. So we decided to discard the flap and to elevate another free flap for the head and neck defect. The donor area on the forearm was covered using the original skin of the first flap as a full-thickness skin graft. This case highlights a means to deal with anomalies of the radial artery encountered during the elevation of RFFF and the checking process for variations of the radial artery before RFFF.</p>","PeriodicalId":52238,"journal":{"name":"Archives of Craniofacial Surgery","volume":"24 1","pages":"28-31"},"PeriodicalIF":0.0,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5a/30/acfs-2022-01032.PMC10009211.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9118061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}