Post reproductive health最新文献_第5页

A service evaluation of an online Cognitive Behaviour Therapy program for troublesome menopausal Hot Flushes and Night Sweats in work settings. 一项在线认知行为治疗项目的服务评估，用于治疗工作环境中令人烦恼的更年期潮热和盗汗。

Post reproductive health Pub Date : 2025-12-01 Epub Date: 2025-06-19 DOI: 10.1177/20533691251352044

Evgenia Stefanopoulou, Samantha Chapelle, David Lewis, Jan Larkin, Myra S Hunter

{"title":"A service evaluation of an online Cognitive Behaviour Therapy program for troublesome menopausal Hot Flushes and Night Sweats in work settings.","authors":"Evgenia Stefanopoulou, Samantha Chapelle, David Lewis, Jan Larkin, Myra S Hunter","doi":"10.1177/20533691251352044","DOIUrl":"10.1177/20533691251352044","url":null,"abstract":"ObjectiveThe most frequently reported menopausal symptoms are hot flushes and night sweats (HFNS). This study evaluated the feasibility, and generated preliminary data on the efficacy, of a self-guided, internet-delivered Cognitive Behaviour Therapy (iCBT) program for HFNS in working menopausal women.MethodsParticipants were UK employees who accessed the iCBT program via an Employee Assistance Program. Adherence consisted of 'non-starters', 'ended as planned (women who received at least 75% of support)' and 'completers'. Program usage, completion rates, user feedback and changes in outcome measures (HFNS frequency, problem-rating, anxiety, depression, work and social adjustment) were assessed.ResultsProgram activation rate was 61%. 426 women accessed an introductory session, with 213 completing the first iCBT session and 62 completing the program. Attrition ranged from 50% to 21% between sessions. Upon completion, there was a significant reduction in all outcome measures. Higher rates of reliable improvement were gained by those with higher anxiety and depression scores at baseline. Most women found the program helpful and easy to use.ConclusionsFindings suggest that an iCBT program for working women experiencing menopausal HFNS is feasible and promising in terms of efficacy. Further studies are needed to establish and implement effective retention strategies to improve compliance with and, thus, the efficacy of self-managed internet-based interventions.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"243-248"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of hormonal replacement therapy on menopausal women with psychosis: A literature review. 激素替代疗法对绝经期精神病妇女的影响：文献综述。

Post reproductive health Pub Date : 2025-12-01 Epub Date: 2025-07-14 DOI: 10.1177/20533691251361018

Nora Shero, Valérie Giroux

{"title":"Impact of hormonal replacement therapy on menopausal women with psychosis: A literature review.","authors":"Nora Shero, Valérie Giroux","doi":"10.1177/20533691251361018","DOIUrl":"10.1177/20533691251361018","url":null,"abstract":"IntroductionRecent literature has explored the use of hormone replacement therapy (HRT) in menopausal women experiencing psychosis. Menopause women with previous psychotic events in their lifetime experience psychotic symptoms at later peak due to the low estrogen production in their bodies, known as menopause-associated psychosis, which can potentially be improved with the help of HRT. This review aims to discuss the effects of HRT on menopausal women with psychosis by comparing studies with combination of antipsychotic drugs.MethodsA literature review using Ovid Medline search was used.ResultsThese results indicate that HRT may have a positive impact on mood and cognition to decrease the expression of psychotic signs. Some estrogen-derived treatments, such as SERM (selective estrogen receptor modulator), might also improve the impact of the antipsychotics, giving the possibility of dosage reduction and fewer side effects.ConclusionSince the management of psychosis is challenging in menopausal women due to hormonal change and antipsychotic adjustment dosage, interdisciplinary management involving psychiatry, gynecology, and family medicine specialities is crucial. This approach can manage the hormonal, psychiatric, and overall medical issues of these patients, provide better psychiatric care, and improve their quality of life. Further research should validate the HRT protocols along with the enhancement of the technique when used in combination with antipsychotic drugs.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"267-272"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12669393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safe prescribing of testosterone in a GP setting: An audit. 在全科医生设置睾酮的安全处方：审计。

Post reproductive health Pub Date : 2025-12-01 Epub Date: 2025-08-07 DOI: 10.1177/20533691251362374

Katie Jenkins, Helen Kini

引用次数: 0

Managing sleep disturbance during the menopause transition. 更年期过渡期睡眠障碍的管理。

Post reproductive health Pub Date : 2025-12-01 Epub Date: 2025-09-18 DOI: 10.1177/20533691251378872

Zoe Schaedel

引用次数: 0

A case of congenital long QT syndrome and medically induced menopause. 临床故事：先天性长QT综合征和药物诱导绝经1例。

Post reproductive health Pub Date : 2025-12-01 Epub Date: 2025-11-14 DOI: 10.1177/20533691251398072

Jane Frances Wilkinson, Paula L Williams, Jan Catherine Green, Simon Modi, Paula E Briggs

引用次数: 0

'Simply do it.': Results from an online questionnaire to inform a community-based menopause education and support programme in the UK, InTune. “只管去做。：来自在线问卷调查的结果，该调查旨在为英国InTune社区的更年期教育和支持计划提供信息。

Post reproductive health Pub Date : 2025-12-01 Epub Date: 2025-09-09 DOI: 10.1177/20533691251372818

Joyce Catherine Harper, Nicky Keay, Mehab Mir, Annice Mukherjee, Jane Plumb, Geeta Kumar, Janet Lindsay, Jeremy Barratt, Sophie Strachan, Shema Tariq

{"title":"'Simply do it.': Results from an online questionnaire to inform a community-based menopause education and support programme in the UK, InTune.","authors":"Joyce Catherine Harper, Nicky Keay, Mehab Mir, Annice Mukherjee, Jane Plumb, Geeta Kumar, Janet Lindsay, Jeremy Barratt, Sophie Strachan, Shema Tariq","doi":"10.1177/20533691251372818","DOIUrl":"10.1177/20533691251372818","url":null,"abstract":"ObjectiveWe are developing a menopause education and support programme, 'InTune', using co-design that includes focus groups and workshops. We have identified the need for two key interventions: one aimed at raising general awareness, Be Prepared for Menopause, and another to support those currently experiencing menopause symptoms. This survey aims to reach a broader audience to better understand their needs and preferences around menopause education and support. The insights gained will help us further develop the InTune programme.Study designAn anonymous, online cross-sectional questionnaire was developed with key stakeholders, covering demographic characteristics, menopause preparedness, and opinions and recommendations for programme design. The survey was conducted online using Qualtrics between 16/1/24 and 22/3/24.Main outcome measuresOf 1596 respondents (98.4% female; 75.6% White British; median age 50 years; 79.5% peri/postmenopausal), 77.4% reported being somewhat informed or not informed about menopause. Over 90% agreed that a national menopause education and support programme was needed, delivered in-person and/or online, in weekly hour-long sessions, over 2-4 weeks. Key to acceptability and success is that information is accessible, accurate, and based on 'latest scientific evidence and debunk[s] some of the myths'. Respondents emphasised the importance of developing a programme that was accessible to all, regardless of gender, ethnicity, age, sexuality, disability status, neurodivergence and age at/cause of menopause.ConclusionOver 90% of participants agreed that a menopause education and support programme with standardised and evidence-based content was needed. This data will allow us to refine the InTune programme.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"255-265"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12669409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of serum estradiol in the menopause transition. 绝经过渡期血清雌二醇的测定。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-09-14 DOI: 10.1177/20533691251366785

Clare Spencer, Heather Currie

引用次数: 0

Differential triage in the postmenopausal bleed clinic; getting it right the first time, effect on single cancer pathway. 绝经后出血临床鉴别分诊第一次就做对了，对单一癌症途径的影响。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-07-19 DOI: 10.1177/20533691251355846

Leena Gokhale, Chris Edwards, Tracey Jones

{"title":"Differential triage in the postmenopausal bleed clinic; getting it right the first time, effect on single cancer pathway.","authors":"Leena Gokhale, Chris Edwards, Tracey Jones","doi":"10.1177/20533691251355846","DOIUrl":"10.1177/20533691251355846","url":null,"abstract":"ObjectiveTo reduce waiting time in PMB clinics, and patient journey on Single cancer pathway.DesignDifferential triage based on risk stratification in USC PMB clinics. Patients with true PMB and with unscheduled bleeding on HRT with risk factors triaged to 2WW. Those with unscheduled bleeding on HRT without risk factors to 6WW clinic. Introduced from March 2024 onwards. Data analysed over 4 months.SettingOne stop PMB clinics, Large DGH in Newport, Wales Population: Aneurin Bevan Health board Hospitals with a population of 600,000.Main outcome measuresTime to first outpatient appointment.ResultsNine hundred and two referrals. 48.22% were not on HRT. 49.88 % were on HRT. 20.44% were on HRT with risk factors. The first outpatient appointment improved from 17.6% in April to 64.6% (p < .0001) in September. Patients breaching the Single Cancer Pathway went down from 11 in April to 2 in September. 88% patients discharged after the FOA. One hundred and ninety-two (21.28%) had a hysteroscopy polypectomy. Forty-four cancers in the true PMB group and 1 cancer in the HRT group. There was no difference in the average BMI between the cancer and benign patients. Patients with endometrial cancer were significantly older (p < .0001***).ConclusionDifferential triage has reduced the waiting times in PMB clinics.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"188-196"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The presence of trigonal non-keratinising squamous metaplasia is not associated with menopausal or estrogen status but may be associated with urinary tract infection in women. 三角形非角化鳞状皮化生与绝经期或雌激素状态无关，但可能与女性尿路感染有关。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-03-18 DOI: 10.1177/20533691251327628

Bernadette Lemmon, Ruwan Fernando, Alex Digesu, Alka Bhide, Miriam Tadros, Vik Khullar

{"title":"The presence of trigonal non-keratinising squamous metaplasia is not associated with menopausal or estrogen status but may be associated with urinary tract infection in women.","authors":"Bernadette Lemmon, Ruwan Fernando, Alex Digesu, Alka Bhide, Miriam Tadros, Vik Khullar","doi":"10.1177/20533691251327628","DOIUrl":"10.1177/20533691251327628","url":null,"abstract":"ObjectiveSquamous metaplasia (SM) at the bladder trigone is often seen during cystoscopy in women. It has previously been described as a normal finding in the literature under the influence of estrogen; however, metaplastic change in epithelium can be activated in response to infection. In this study, we hypothesise that trigonal SM is indicative of urinary tract infection (UTI) in pre- and post-menopausal women irrespective of estrogen status.Study DesignDescriptions of the bladder trigone were retrospectively reviewed in the surgical notes of pre- and post-menopausal women who underwent cystoscopy for presence of SM. Results of urine and tissue cultures were also reviewed with UTI being defined as a positive urine and/or bladder tissue culture.Main Outcome MeasuresThe statistical relationship between the presence of trigonal SM and culture positive UTI.Results97 women were included with 39 post-menopausal (40%) and 58 pre-menopausal (60%). SM had a 62% positive predictive value of UTI, and a negative predictive value of 73% (sensitivity = 93%, specificity = 76%). Chi-squared showed that there is a statistically significant relationship between trigonal SM and UTI p = .015. Bladder tissue was more likely to identify a uropathogen in women with severe SM. We found no significant relationship between estrogen status and the presence of SM (p = .866).ConclusionsThis study shows that the cystoscopic appearance of SM is associated with infection in the bladder independent of menopausal status or exposure to externally taken estrogen. This may be a particularly helpful finding in women with recurrent symptoms of UTI but negative culture results.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"153-158"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of developing a new tool for assessing vaginal health in women with Genitourinary Syndrome of Menopause; The VAN study. 开发一种评估绝经期泌尿生殖系统综合征妇女阴道健康的新工具的可行性VAN研究。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-04-13 DOI: 10.1177/20533691251332321

Paula Briggs, Christopher Evans, Steven Lane, Lora Kiosseva, Jo Drury, Tim Hillard, Nick Panay, Dharani K Hapangama

{"title":"Feasibility of developing a new tool for assessing vaginal health in women with Genitourinary Syndrome of Menopause; The VAN study.","authors":"Paula Briggs, Christopher Evans, Steven Lane, Lora Kiosseva, Jo Drury, Tim Hillard, Nick Panay, Dharani K Hapangama","doi":"10.1177/20533691251332321","DOIUrl":"10.1177/20533691251332321","url":null,"abstract":"ObjectivesGenitourinary syndrome of menopause (GSM) is a common condition, yet there is no accessible, objective clinical method with which to make a diagnosis of vaginal changes associated with GSM. We undertook a feasibility study to assess suitability of different objective diagnostic methods and obtained quantitative scores using a new GSM Assessment Tool (NGAT) and vaginal maturation vlue (VMV). These scores were correlated with patient reported symptoms obtained via a questionnaire.Study DesignVAginal Health - What's Normal (VAN) Study is a prospective, observational, feasibility study, evaluating NGAT and VMV. Sixty women (12 healthy controls and 48 symptomatic) were recruited and had a baseline assessment. The symptomatic women were offered treatment and had a second assessment 16 weeks later.ResultsCompared with control group, symptomatic women had higher NGAT and VMV scores at baseline. After treatment, in symptomatic women, symptoms improved and NGAT scores reduced, while the median value for VMV was unexpectedly reduced.ConclusionsThis data suggests that clinical assessment and accurate recording of GSM can be supported by an objective scoring system, particularly in primary care and warrants adequately powered future studies to assess the utility of these methods in clinical and research setting.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"163-172"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0