{"title":"Impact of hormonal replacement therapy on menopausal women with psychosis: A literature review.","authors":"Nora Shero, Valérie Giroux","doi":"10.1177/20533691251361018","DOIUrl":"https://doi.org/10.1177/20533691251361018","url":null,"abstract":"<p><p>IntroductionRecent literature has explored the use of hormone replacement therapy (HRT) in menopausal women experiencing psychosis. Menopause women with previous psychotic events in their lifetime experience psychotic symptoms at later peak due to the low estrogen production in their bodies, known as menopause-associated psychosis, which can potentially be improved with the help of HRT. This review aims to discuss the effects of HRT on menopausal women with psychosis by comparing studies with combination of antipsychotic drugs.MethodsA literature review using Ovid Medline search was used.ResultsThese results indicate that HRT may have a positive impact on mood and cognition to decrease the expression of psychotic signs. Some estrogen-derived treatments, such as SERM (selective estrogen receptor modulator), might also improve the impact of the antipsychotics, giving the possibility of dosage reduction and fewer side effects.ConclusionSince the management of psychosis is challenging in menopausal women due to hormonal change and antipsychotic adjustment dosage, interdisciplinary management involving psychiatry, gynecology, and family medicine specialities is crucial. This approach can manage the hormonal, psychiatric, and overall medical issues of these patients, provide better psychiatric care, and improve their quality of life. Further research should validate the HRT protocols along with the enhancement of the technique when used in combination with antipsychotic drugs.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251361018"},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evgenia Stefanopoulou, Samantha Chapelle, David Lewis, Jan Larkin, Myra S Hunter
{"title":"A service evaluation of an online Cognitive Behaviour Therapy program for troublesome menopausal Hot Flushes and Night Sweats in work settings.","authors":"Evgenia Stefanopoulou, Samantha Chapelle, David Lewis, Jan Larkin, Myra S Hunter","doi":"10.1177/20533691251352044","DOIUrl":"10.1177/20533691251352044","url":null,"abstract":"<p><p>ObjectiveThe most frequently reported menopausal symptoms are hot flushes and night sweats (HFNS). This study evaluated the feasibility, and generated preliminary data on the efficacy, of a self-guided, internet-delivered Cognitive Behaviour Therapy (iCBT) program for HFNS in working menopausal women.MethodsParticipants were UK employees who accessed the iCBT program via an Employee Assistance Program. Adherence consisted of 'non-starters', 'ended as planned (women who received at least 75% of support)' and 'completers'. Program usage, completion rates, user feedback and changes in outcome measures (HFNS frequency, problem-rating, anxiety, depression, work and social adjustment) were assessed.ResultsProgram activation rate was 61%. 426 women accessed an introductory session, with 213 completing the first iCBT session and 62 completing the program. Attrition ranged from 50% to 21% between sessions. Upon completion, there was a significant reduction in all outcome measures. Higher rates of reliable improvement were gained by those with higher anxiety and depression scores at baseline. Most women found the program helpful and easy to use.ConclusionsFindings suggest that an iCBT program for working women experiencing menopausal HFNS is feasible and promising in terms of efficacy. Further studies are needed to establish and implement effective retention strategies to improve compliance with and, thus, the efficacy of self-managed internet-based interventions.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251352044"},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-07-02DOI: 10.1177/20533691251350518
Rosie H Musgrave, Sara Nowakowski, Tamlyn J Watermeyer, Emily J Arentson-Lantz, Greg J Elder
{"title":"Dietary interventions to support and improve sleep disturbances and insomnia disorder in menopause: From bench to bedside.","authors":"Rosie H Musgrave, Sara Nowakowski, Tamlyn J Watermeyer, Emily J Arentson-Lantz, Greg J Elder","doi":"10.1177/20533691251350518","DOIUrl":"10.1177/20533691251350518","url":null,"abstract":"<p><p>Sleep is essential for maintaining physical and psychological health, and also cognitive health (referred to as 'brain health'). However, the transition to menopause has a direct impact upon sleep. Sleep disturbances are reported by approximately 40%-60% of menopausal women, and insomnia disorder is also prevalent. Diet-based interventions could potentially be used to improve subjective sleep quality in this population, and although there are several promising interventions which have been used in other groups that could be trialled, the evidence base is currently lacking. One particularly promising area for future research is that these interventions might be used alongside, or instead of, established treatments for insomnia disorder. This may also help to prevent the development of longer-term insomnia disorder. Future studies should use well-controlled, adequately powered, clinical trial designs to assess the effectiveness of dietary interventions in improving subjective sleep quality, treating insomnia disorder, and preventing acute sleep disturbances from progressing to chronic insomnia. Given the strong association between sleep and neurodegeneration, optimizing sleep in menopausal women, using targeted diet-based strategies, may have significant implications for brain health.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":"31 2","pages":"122-126"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-07-02DOI: 10.1177/20533691251345940
Anne Marie Minihane
{"title":"Nutrition and menopausal well-being.","authors":"Anne Marie Minihane","doi":"10.1177/20533691251345940","DOIUrl":"https://doi.org/10.1177/20533691251345940","url":null,"abstract":"","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":"31 2","pages":"59-60"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-05-07DOI: 10.1177/20533691251340491
Marrium Liaquat, Anne Marie Minihane, David Vauzour, Matthew G Pontifex
{"title":"The gut microbiota in menopause: Is there a role for prebiotic and probiotic solutions?","authors":"Marrium Liaquat, Anne Marie Minihane, David Vauzour, Matthew G Pontifex","doi":"10.1177/20533691251340491","DOIUrl":"10.1177/20533691251340491","url":null,"abstract":"<p><p>The gut microbiota, comprising a diverse array of microorganisms in the gastrointestinal tract, has emerged as a key player in human health. Emerging research indicates that this gut microbial composition is influenced by sex. These sex differences are not necessarily static and likely alter across the life course in response to several factors including changing hormone profile. As such, the menopause transition-a pivotal phase in female ageing in which the hormone profile changes dramatically is receiving increasing attention. Declining estrogen which occurs during menopause appears to influence the microbiota, which may in turn contribute to menopause-related conditions such as weight gain, bone health, cancer risk and cognitive health. The modulation of estrogen through the gut's 'estrobolome', a collection of bacterial genes involved in estrogen metabolism, may offer explanation for some of the interindividual differences observed during menopause (e.g. length, symptoms and disease risk). Therapeutic modulation of the gut microbiota therefore represents a potential approach towards managing menopausal symptoms. Indeed, prebiotics and probiotics such as <i>Lactobacillus</i> have been shown to increase bacterial diversity and improve metabolic and overall health in menopausal women. However, evidence remains limited regarding the specific underlying mechanisms, highlighting an urgent need for a research focus in the area. This review summarizes the current understanding of the gut microbiota's role in menopausal health and the potential of prebiotics and probiotics as therapeutic interventions. Further research into gut microbiota modulation may enable more effective, personalised treatments for menopause-associated health challenges, and supporting women's health into older ages.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"105-114"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-05-02DOI: 10.1177/20533691251339566
Nicola Best
{"title":"Dietary patterns and their associations with body composition, cardiometabolic and bone health in postmenopausal women.","authors":"Nicola Best","doi":"10.1177/20533691251339566","DOIUrl":"10.1177/20533691251339566","url":null,"abstract":"<p><p><b>Background:</b> Menopause, occurring typically between ages 45 and 55, is associated with various physical and psychological symptoms and an increased risk of cardiometabolic diseases, osteoporosis and obesity. <b>Purpose and Research Design:</b> This review examines the impact of healthy dietary patterns in postmenopausal women, focussing on recent literature on the Mediterranean Diet, Dietary Approaches to Stop Hypertension (DASH), the Portfolio diet and other national healthy eating guidelines.<b>Results:</b> Evidence suggests that adhering to one of these healthy dietary patterns can reduce the risk of cardiometabolic diseases and may benefit body composition and bone health.<b>Conclusions:</b> Although promising, the current evidence, primarily from observational studies, requires more extensive and long-term intervention trials to establish definite conclusions. This review underscores the importance of dietary choices in supporting postmenopausal health and highlights the need for comprehensive dietary strategies tailored to regional eating habits.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"87-95"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-05-16DOI: 10.1177/20533691251343069
Annice Mukherjee, Sadaf Ghaem-Maghami, Akheel A Syed
{"title":"Use of incretin-based therapies in women using hormone replacement therapy (HRT).","authors":"Annice Mukherjee, Sadaf Ghaem-Maghami, Akheel A Syed","doi":"10.1177/20533691251343069","DOIUrl":"10.1177/20533691251343069","url":null,"abstract":"","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"127-131"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144082011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-05-28DOI: 10.1177/20533691251346293
Susan Waigwa, Paula Briggs, Susan Pickard, Elham Amini, Jane Wilkinson
{"title":"Tales from the photovoice clinic: Menopause experiences of Black and Chinese women in the United Kingdom.","authors":"Susan Waigwa, Paula Briggs, Susan Pickard, Elham Amini, Jane Wilkinson","doi":"10.1177/20533691251346293","DOIUrl":"10.1177/20533691251346293","url":null,"abstract":"<p><p>BackgroundMenopause is one of many critical life course points that may require intervention in relation to lifestyle changes, health and wellbeing. It is therefore important that menopausal women are supported especially considering possible health inequalities and inclusion issues. While there is increasing recognition for such support, little is known about the experiences of ethnic minority women living in the United Kingdom, who are thought to be less engaged and less likely to seek support, but those who try to seek support experience dissatisfaction.MethodsThis study explored menopause experiences of Black and Chinese heritage women aged over 40, living in the Northwest, England. Photovoice methodology was utilised including a four-phase process: introductory meeting with participants, taking of photos, selection of photos and discussions about the photos. Ten women participated and provided photos that conveyed their experiences with menopause. Photographs and transcripts from discussions were then analysed thematically.ResultsNine overarching themes were identified across the data: Menopause and management of symptoms including self-care, diet management, exercise, community and menopause and the life course including religion and beliefs, work, family and ageing. These themes captured the challenges and expectation of interacting with healthcare providers, alternative methods of managing menopause, significance of community and focus on the life course.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"132-139"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2024-12-13DOI: 10.1177/20533691241308370
Eleanor Davies, Vanessa Halliday
{"title":"Nutrition information and the menopause: An online survey of perimenopausal and menopausal women.","authors":"Eleanor Davies, Vanessa Halliday","doi":"10.1177/20533691241308370","DOIUrl":"10.1177/20533691241308370","url":null,"abstract":"<p><p>ObjectiveThis study aimed to explore where perimenopausal and menopausal women get their nutrition information from, and how reliable they perceive these sources to be.Study designThis was a cross-sectional study that used an online survey to collect data about nutrition information seeking habits. The survey was generated using the Qualtrics software and promoted via social media. The convenience sample included women over the age of 40 years living in the UK. Main outcome measures: Quantitative data.ResultsTwo hundred and sixty-nine responses were analysed. The majority of respondents were over the age of 50, and from a white British background. Online sources were most commonly used by women to access nutrition information, namely official websites such as the British Menopause Society (BMS) and National Health Service (NHS) websites. The majority of participants believed that these, along with research papers, were the most reliable sources. However, receiving nutrition information from healthcare professionals was most likely to cause women to change their behaviour towards nutrition. The majority of women were interested in receiving targeted menopausal nutrition information, and this would ideally be from official websites or their healthcare professionals.ConclusionsFindings from this study suggest that women predominantly rely on online sources for information about nutrition, perceiving official websites as reliable sources. There is a demand among women for tailored nutritional guidance during the menopausal transition, emphasising the importance of providing accessible and targeted resources to support women's health needs during this life stage.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"65-72"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Post reproductive healthPub Date : 2025-06-01Epub Date: 2025-05-30DOI: 10.1177/20533691251341701
Anne Marie Minihane
{"title":"Omega-3 fatty acids, brain health and the menopause.","authors":"Anne Marie Minihane","doi":"10.1177/20533691251341701","DOIUrl":"10.1177/20533691251341701","url":null,"abstract":"<p><p>The menopausal transition is associated with vasomotor symptoms, disrupted sleep, transient cognitive deficits and changes in mood and anxiety levels, underpinned by declining and erratic estrogen availability in the brain. Relative to other tissues the brain is enriched in the omega-3 fatty acid, docosahexaenoic (DHA), with well-defined neurophysiological roles for both eicosapentaenoic acid (EPA) and DHA. Substantial preclinical and epidemiological evidence along with accumulating randomised controlled trial (RCT) data indicates that an increase in EPA and DHA intake and status is associated with improved brain function. In this narrative review, the role of EPA and DHA in the menopausal transition (MT) is considered. The evidence, although relatively sparse, is indicative of benefit, with future RCTs needed to establish dose-response relationships and when it is most beneficial to intervene. Although research is at a relatively early stage, the MT is emerging as a critical window of intervention opportunity not only to support MT well-being but also lifelong health in women.</p>","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"97-104"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}