Post reproductive health最新文献

Collaborative working with secondary care to enable increased provision of menopause care by primary care services. 与二级保健机构合作，通过初级保健服务增加更年期护理的提供。

Post reproductive health Pub Date : 2025-09-20 DOI: 10.1177/20533691251372816

Veena Kaul, Debbie Hallott

{"title":"Collaborative working with secondary care to enable increased provision of menopause care by primary care services.","authors":"Veena Kaul, Debbie Hallott","doi":"10.1177/20533691251372816","DOIUrl":"10.1177/20533691251372816","url":null,"abstract":"BackgroundThe vast majority of menopause care is delivered by primary care services; however, in recent years there has been an increase in referrals to secondary care services resulting in longer waiting times for patients.AimFacilitate the delivery of effective and timely menopause care for women without need for referral and long waits at Mid Yorkshire Hospital Teaching Trust (MYHTT). This required collaboration between primary and secondary care services.Methods(1) Development of joint Menopause Care & HRT Formulary. (2) Review of Menopause Referrals to MYHTT. (3) Developing Women's Health Leads network & Women's Health Hub via Microsoft Teams channel. (4) Streamlining management of unscheduled bleeding on HRT. (5) Developed Patient information for Menopause and HRT leaflets in the five most spoken languages in our community.ResultsOver 70% reduction in referrals to MYHTT to menopause service and over 30% reduction in referrals to post-menopausal bleeding clinics. It demonstrates that our shared learning approach has bridged the gap between primary and secondary care, creating a more supportive and inclusive healthcare environment.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251372816"},"PeriodicalIF":0.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Managing sleep disturbance during the menopause transition. 更年期过渡期睡眠障碍的管理。

Post reproductive health Pub Date : 2025-09-18 DOI: 10.1177/20533691251378872

Zoe Schaedel

引用次数: 0

'Simply do it.': Results from an online questionnaire to inform a community-based menopause education and support programme in the UK, InTune. “只管去做。：来自在线问卷调查的结果，该调查旨在为英国InTune社区的更年期教育和支持计划提供信息。

Post reproductive health Pub Date : 2025-09-09 DOI: 10.1177/20533691251372818

Joyce Catherine Harper, Nicky Keay, Mehab Mir, Annice Mukherjee, Jane Plumb, Geeta Kumar, Janet Lindsay, Jeremy Barratt, Sophie Strachan, Shema Tariq

{"title":"'Simply do it.': Results from an online questionnaire to inform a community-based menopause education and support programme in the UK, InTune.","authors":"Joyce Catherine Harper, Nicky Keay, Mehab Mir, Annice Mukherjee, Jane Plumb, Geeta Kumar, Janet Lindsay, Jeremy Barratt, Sophie Strachan, Shema Tariq","doi":"10.1177/20533691251372818","DOIUrl":"https://doi.org/10.1177/20533691251372818","url":null,"abstract":"ObjectiveWe are developing a menopause education and support programme, 'InTune', using co-design that includes focus groups and workshops. We have identified the need for two key interventions: one aimed at raising general awareness, Be Prepared for Menopause, and another to support those currently experiencing menopause symptoms. This survey aims to reach a broader audience to better understand their needs and preferences around menopause education and support. The insights gained will help us further develop the InTune programme.Study designAn anonymous, online cross-sectional questionnaire was developed with key stakeholders, covering demographic characteristics, menopause preparedness, and opinions and recommendations for programme design. The survey was conducted online using Qualtrics between 16/1/24 and 22/3/24.Main outcome measuresOf 1596 respondents (98.4% female; 75.6% White British; median age 50 years; 79.5% peri/postmenopausal), 77.4% reported being somewhat informed or not informed about menopause. Over 90% agreed that a national menopause education and support programme was needed, delivered in-person and/or online, in weekly hour-long sessions, over 2-4 weeks. Key to acceptability and success is that information is accessible, accurate, and based on 'latest scientific evidence and debunk[s] some of the myths'. Respondents emphasised the importance of developing a programme that was accessible to all, regardless of gender, ethnicity, age, sexuality, disability status, neurodivergence and age at/cause of menopause.ConclusionOver 90% of participants agreed that a menopause education and support programme with standardised and evidence-based content was needed. This data will allow us to refine the InTune programme.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251372818"},"PeriodicalIF":0.0,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145031113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of serum estradiol in the menopause transition. 绝经过渡期血清雌二醇的测定。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-09-14 DOI: 10.1177/20533691251366785

Clare Spencer, Heather Currie

引用次数: 0

Differential triage in the postmenopausal bleed clinic; getting it right the first time, effect on single cancer pathway. 绝经后出血临床鉴别分诊第一次就做对了，对单一癌症途径的影响。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-07-19 DOI: 10.1177/20533691251355846

Leena Gokhale, Chris Edwards, Tracey Jones

{"title":"Differential triage in the postmenopausal bleed clinic; getting it right the first time, effect on single cancer pathway.","authors":"Leena Gokhale, Chris Edwards, Tracey Jones","doi":"10.1177/20533691251355846","DOIUrl":"10.1177/20533691251355846","url":null,"abstract":"ObjectiveTo reduce waiting time in PMB clinics, and patient journey on Single cancer pathway.DesignDifferential triage based on risk stratification in USC PMB clinics. Patients with true PMB and with unscheduled bleeding on HRT with risk factors triaged to 2WW. Those with unscheduled bleeding on HRT without risk factors to 6WW clinic. Introduced from March 2024 onwards. Data analysed over 4 months.SettingOne stop PMB clinics, Large DGH in Newport, Wales Population: Aneurin Bevan Health board Hospitals with a population of 600,000.Main outcome measuresTime to first outpatient appointment.ResultsNine hundred and two referrals. 48.22% were not on HRT. 49.88 % were on HRT. 20.44% were on HRT with risk factors. The first outpatient appointment improved from 17.6% in April to 64.6% (p < .0001) in September. Patients breaching the Single Cancer Pathway went down from 11 in April to 2 in September. 88% patients discharged after the FOA. One hundred and ninety-two (21.28%) had a hysteroscopy polypectomy. Forty-four cancers in the true PMB group and 1 cancer in the HRT group. There was no difference in the average BMI between the cancer and benign patients. Patients with endometrial cancer were significantly older (p < .0001***).ConclusionDifferential triage has reduced the waiting times in PMB clinics.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"188-196"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The presence of trigonal non-keratinising squamous metaplasia is not associated with menopausal or estrogen status but may be associated with urinary tract infection in women. 三角形非角化鳞状皮化生与绝经期或雌激素状态无关，但可能与女性尿路感染有关。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-03-18 DOI: 10.1177/20533691251327628

Bernadette Lemmon, Ruwan Fernando, Alex Digesu, Alka Bhide, Miriam Tadros, Vik Khullar

{"title":"The presence of trigonal non-keratinising squamous metaplasia is not associated with menopausal or estrogen status but may be associated with urinary tract infection in women.","authors":"Bernadette Lemmon, Ruwan Fernando, Alex Digesu, Alka Bhide, Miriam Tadros, Vik Khullar","doi":"10.1177/20533691251327628","DOIUrl":"10.1177/20533691251327628","url":null,"abstract":"ObjectiveSquamous metaplasia (SM) at the bladder trigone is often seen during cystoscopy in women. It has previously been described as a normal finding in the literature under the influence of estrogen; however, metaplastic change in epithelium can be activated in response to infection. In this study, we hypothesise that trigonal SM is indicative of urinary tract infection (UTI) in pre- and post-menopausal women irrespective of estrogen status.Study DesignDescriptions of the bladder trigone were retrospectively reviewed in the surgical notes of pre- and post-menopausal women who underwent cystoscopy for presence of SM. Results of urine and tissue cultures were also reviewed with UTI being defined as a positive urine and/or bladder tissue culture.Main Outcome MeasuresThe statistical relationship between the presence of trigonal SM and culture positive UTI.Results97 women were included with 39 post-menopausal (40%) and 58 pre-menopausal (60%). SM had a 62% positive predictive value of UTI, and a negative predictive value of 73% (sensitivity = 93%, specificity = 76%). Chi-squared showed that there is a statistically significant relationship between trigonal SM and UTI p = .015. Bladder tissue was more likely to identify a uropathogen in women with severe SM. We found no significant relationship between estrogen status and the presence of SM (p = .866).ConclusionsThis study shows that the cystoscopic appearance of SM is associated with infection in the bladder independent of menopausal status or exposure to externally taken estrogen. This may be a particularly helpful finding in women with recurrent symptoms of UTI but negative culture results.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"153-158"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of developing a new tool for assessing vaginal health in women with Genitourinary Syndrome of Menopause; The VAN study. 开发一种评估绝经期泌尿生殖系统综合征妇女阴道健康的新工具的可行性VAN研究。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-04-13 DOI: 10.1177/20533691251332321

Paula Briggs, Christopher Evans, Steven Lane, Lora Kiosseva, Jo Drury, Tim Hillard, Nick Panay, Dharani K Hapangama

{"title":"Feasibility of developing a new tool for assessing vaginal health in women with Genitourinary Syndrome of Menopause; The VAN study.","authors":"Paula Briggs, Christopher Evans, Steven Lane, Lora Kiosseva, Jo Drury, Tim Hillard, Nick Panay, Dharani K Hapangama","doi":"10.1177/20533691251332321","DOIUrl":"10.1177/20533691251332321","url":null,"abstract":"ObjectivesGenitourinary syndrome of menopause (GSM) is a common condition, yet there is no accessible, objective clinical method with which to make a diagnosis of vaginal changes associated with GSM. We undertook a feasibility study to assess suitability of different objective diagnostic methods and obtained quantitative scores using a new GSM Assessment Tool (NGAT) and vaginal maturation vlue (VMV). These scores were correlated with patient reported symptoms obtained via a questionnaire.Study DesignVAginal Health - What's Normal (VAN) Study is a prospective, observational, feasibility study, evaluating NGAT and VMV. Sixty women (12 healthy controls and 48 symptomatic) were recruited and had a baseline assessment. The symptomatic women were offered treatment and had a second assessment 16 weeks later.ResultsCompared with control group, symptomatic women had higher NGAT and VMV scores at baseline. After treatment, in symptomatic women, symptoms improved and NGAT scores reduced, while the median value for VMV was unexpectedly reduced.ConclusionsThis data suggests that clinical assessment and accurate recording of GSM can be supported by an objective scoring system, particularly in primary care and warrants adequately powered future studies to assess the utility of these methods in clinical and research setting.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"163-172"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obituary: Dr Tony Mander. 讣告：托尼·曼德博士。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-09-14 DOI: 10.1177/20533691251368695

Ann Jones, Edward Morris

引用次数: 0

Rethinking sarcopenia and frailty of the elderly. 老年人肌肉减少症与虚弱的再思考。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-04-22 DOI: 10.1177/20533691251337173

Janice Blumer, Bachtuyet Le

{"title":"Rethinking sarcopenia and frailty of the elderly.","authors":"Janice Blumer, Bachtuyet Le","doi":"10.1177/20533691251337173","DOIUrl":"10.1177/20533691251337173","url":null,"abstract":"Sarcopenia, or 'frailty of the elderly', is a condition of low muscle mass which is prevalent in older adults and post-menopausal women, leading to falls or worsening after falls. Age-related muscle thinning contributes to falls and fractures. Fractures lead to downward spiral toward the loss of independence in the elderly and ultimately, increased health care expenditures of approximately 4 billion pounds a year. The diagnosis of sarcopenia is based on muscle mass, muscle strength, and physical performance. Sarcopenia is caused by imbalance between the anabolic and catabolic processes on the protein production pathway, as well as a decrease in satellite cells. Denervation, inflammation, hormonal changes, and mitochondrial decline further complicate the issue. Is it time that physicians begin to rethink the diagnosis of sarcopenia or frailty as a process that begins in mid-life? In women, it begins in menopause and ends with falls, fractures, or immobility due to weakness. Physicians often question which came first; frailty causing the fall or the fall worsening frailty, which leads to challenges in treatment. Sarcopenia treatment involves resistance training, appropriate diet and being proactive about the diagnosis. These low-risk lifestyle interventions should be recommended during mid-life well woman visits. Physicians can influence the outcomes of sarcopenia simply by providing an exercise prescription, supplement, and diet recommendation in early menopause. This article aims to change the thinking around sarcopenia from an 'end stage' diagnosis to a mid-life discussion around disease prevention and maintenance of health and muscle.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"184-187"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiovascular outcomes of menopause hormone therapy initiated in women aged ≥60 years or ≥10 years post-menopause: A systematic review of the literature. ≥60岁或≥10年绝经后妇女开始绝经激素治疗的心血管结局：文献系统综述

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-05-09 DOI: 10.1177/20533691251341713

Nancy Yaneth Contreras Garza, José Antonio Dávila Rivas, Carlos Félix Arce, María Elizabeth Fraustro Avila, Celina Salas Castro, Sergio Alejandro Villarreal González, Grecia Villa Cruz, Belinda Maricela Contreras Garza, José Luis Neyro Bilbao

{"title":"Cardiovascular outcomes of menopause hormone therapy initiated in women aged ≥60 years or ≥10 years post-menopause: A systematic review of the literature.","authors":"Nancy Yaneth Contreras Garza, José Antonio Dávila Rivas, Carlos Félix Arce, María Elizabeth Fraustro Avila, Celina Salas Castro, Sergio Alejandro Villarreal González, Grecia Villa Cruz, Belinda Maricela Contreras Garza, José Luis Neyro Bilbao","doi":"10.1177/20533691251341713","DOIUrl":"10.1177/20533691251341713","url":null,"abstract":"IntroductionMenopause hormone therapy (MHT) is the most effective treatment for climacteric syndrome. However, its cardiovascular effects remain complex. The 'timing hypothesis' suggests these effects depend on the timing of initiation, but this has been increasingly questioned. This study evaluates evidence on cardiovascular risks associated with late MHT initiation in healthy women aged ≥60 years or ≥10 years post-menopause.MethodsA comprehensive literature search was conducted from the inception of each database until November 2023. The databases searched included PubMed, SciELO, Embase, and Cochrane. RCTs of human studies examining the cardiovascular effects of MHT in healthy women aged ≥60 years or those ≥10 years post-menopause were included. Eligibility screening, data extraction, risk of bias assessment were performed independently and in duplicate.ResultsNine RCTs comprising 36,051 participants were included. We focus on results from participants aged ≥60 years. The mean follow-up was 7.2 years. Six studies were sub-analyses of the Women's Health Initiative (WHI) trial, while three studies originated from other trials. Results from the WHI indicated no significant increase in cardiovascular risks with either CEE + MPA or Estrogen-only therapy. Non-WHI studies showed an elevated stroke risk with tibolone and higher doses of combined MHT, but no cardiovascular complications were observed with low doses.ConclusionThe increased risk of cardiovascular events in our target population is not statistically significant. There is a lack of high-quality evidence to suggest an increased risk of adverse cardiovascular outcomes in healthy women who initiate MHT at age ≥60 years or ≥10 years post-menopause.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"173-183"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144025093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0