Post reproductive health最新文献_第2页

Results of a patient survey exploring skin symptoms in a menopause clinic. 绝经期门诊患者皮肤症状调查结果。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-04-02 DOI: 10.1177/20533691251332403

Hamisha Salih, Zoe Schaedel, Olivia Hum, Claudia DeGiovanni

引用次数: 0

Uniting minds and advancing menopause care: Reflections from the 2025 British Menopause Society Conference. 团结思想，推进更年期护理：从2025年英国更年期学会会议的反思。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-08-22 DOI: 10.1177/20533691251366801

Katie Barber, Nick Panay

引用次数: 0

News and views. 新闻和观点。

Post reproductive health Pub Date : 2025-09-01 Epub Date: 2025-08-12 DOI: 10.1177/20533691251368694

Simon Brown

引用次数: 0

The use of HRT containing transdermal estradiol in women with a personal history of venous or arterial thromboembolism: A consecutive series of 115 cases. 有静脉或动脉血栓栓塞史的妇女使用含经皮雌二醇的激素替代疗法：连续115例。

Post reproductive health Pub Date : 2025-08-22 DOI: 10.1177/20533691251369205

Phoebe Howells, Sadiya Hussain, Emily Hulme, Kugajeevan Vigneswaran, Samar Zia, Mohsen Hassan, Roopen Arya, Haitham Hamoda

{"title":"The use of HRT containing transdermal estradiol in women with a personal history of venous or arterial thromboembolism: A consecutive series of 115 cases.","authors":"Phoebe Howells, Sadiya Hussain, Emily Hulme, Kugajeevan Vigneswaran, Samar Zia, Mohsen Hassan, Roopen Arya, Haitham Hamoda","doi":"10.1177/20533691251369205","DOIUrl":"https://doi.org/10.1177/20533691251369205","url":null,"abstract":"ObjectiveTo assess the risk of further thrombosis with using HRT containing transdermal estradiol in women with a personal history of venous thromboembolism (VTE) or arterial thromboembolism (ATE).MethodsWe undertook analysis of patients with a history of VTE/ATE who had been seen in the menopause clinic at King's College Hospital. They were followed up for a minimum of a 12 months period to assess for recurrence of VTE/ATE.ResultsThe study included 115 patients with a personal history of VTE/ATE who had used HRT for over a year. 81% had a history of a VTE, 19% had suffered from an ATE. Patients had taken HRT containing transdermal estradiol +/- micronised progesterone or Mirena coil or combined transdermal HRT for a range of 1-20 years, with an average duration of 3 years. 11 patients had switched from oral HRT to transdermal HRT after visiting the clinic. All patients had been referred to a haematologist with 20% of patients requiring life-long anticoagulation based on their medcial background history. 64% of the patients had documented thrombophilia results with 42% of those being positive for a thrombophilia. 39/115 patients required a higher dose of estrogen, taking either more than two pumps of gel/spray or >50 micrograms in the form of a patch. Significantly on follow up (up to 12 months or more), none of the patients had a recurrence of a thromboembolism within 12 months of starting HRT containing transdermal estradiol.ConclusionTo our knowledge, this is the first study assessing the use of HRT containing transdermal estradiol in women with a personal history of VTE/ATE. None of the patients assessed had a thromboembolic event within 12 months of follow up. This study will enable more clinicians to consider prescribing HRT in patients with a personal history of VTE/ATE and higher patient uptake, after individualised risk-assessments.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251369205"},"PeriodicalIF":0.0,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Safe prescribing of testosterone in a GP setting: An audit. 在全科医生设置睾酮的安全处方：审计。

Post reproductive health Pub Date : 2025-08-07 DOI: 10.1177/20533691251362374

Katie Jenkins, Helen Kini

引用次数: 0

Impact of hormonal replacement therapy on menopausal women with psychosis: A literature review. 激素替代疗法对绝经期精神病妇女的影响：文献综述。

Post reproductive health Pub Date : 2025-07-14 DOI: 10.1177/20533691251361018

Nora Shero, Valérie Giroux

{"title":"Impact of hormonal replacement therapy on menopausal women with psychosis: A literature review.","authors":"Nora Shero, Valérie Giroux","doi":"10.1177/20533691251361018","DOIUrl":"https://doi.org/10.1177/20533691251361018","url":null,"abstract":"IntroductionRecent literature has explored the use of hormone replacement therapy (HRT) in menopausal women experiencing psychosis. Menopause women with previous psychotic events in their lifetime experience psychotic symptoms at later peak due to the low estrogen production in their bodies, known as menopause-associated psychosis, which can potentially be improved with the help of HRT. This review aims to discuss the effects of HRT on menopausal women with psychosis by comparing studies with combination of antipsychotic drugs.MethodsA literature review using Ovid Medline search was used.ResultsThese results indicate that HRT may have a positive impact on mood and cognition to decrease the expression of psychotic signs. Some estrogen-derived treatments, such as SERM (selective estrogen receptor modulator), might also improve the impact of the antipsychotics, giving the possibility of dosage reduction and fewer side effects.ConclusionSince the management of psychosis is challenging in menopausal women due to hormonal change and antipsychotic adjustment dosage, interdisciplinary management involving psychiatry, gynecology, and family medicine specialities is crucial. This approach can manage the hormonal, psychiatric, and overall medical issues of these patients, provide better psychiatric care, and improve their quality of life. Further research should validate the HRT protocols along with the enhancement of the technique when used in combination with antipsychotic drugs.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251361018"},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A service evaluation of an online Cognitive Behaviour Therapy program for troublesome menopausal Hot Flushes and Night Sweats in work settings. 一项在线认知行为治疗项目的服务评估，用于治疗工作环境中令人烦恼的更年期潮热和盗汗。

Post reproductive health Pub Date : 2025-06-19 DOI: 10.1177/20533691251352044

Evgenia Stefanopoulou, Samantha Chapelle, David Lewis, Jan Larkin, Myra S Hunter

{"title":"A service evaluation of an online Cognitive Behaviour Therapy program for troublesome menopausal Hot Flushes and Night Sweats in work settings.","authors":"Evgenia Stefanopoulou, Samantha Chapelle, David Lewis, Jan Larkin, Myra S Hunter","doi":"10.1177/20533691251352044","DOIUrl":"10.1177/20533691251352044","url":null,"abstract":"ObjectiveThe most frequently reported menopausal symptoms are hot flushes and night sweats (HFNS). This study evaluated the feasibility, and generated preliminary data on the efficacy, of a self-guided, internet-delivered Cognitive Behaviour Therapy (iCBT) program for HFNS in working menopausal women.MethodsParticipants were UK employees who accessed the iCBT program via an Employee Assistance Program. Adherence consisted of 'non-starters', 'ended as planned (women who received at least 75% of support)' and 'completers'. Program usage, completion rates, user feedback and changes in outcome measures (HFNS frequency, problem-rating, anxiety, depression, work and social adjustment) were assessed.ResultsProgram activation rate was 61%. 426 women accessed an introductory session, with 213 completing the first iCBT session and 62 completing the program. Attrition ranged from 50% to 21% between sessions. Upon completion, there was a significant reduction in all outcome measures. Higher rates of reliable improvement were gained by those with higher anxiety and depression scores at baseline. Most women found the program helpful and easy to use.ConclusionsFindings suggest that an iCBT program for working women experiencing menopausal HFNS is feasible and promising in terms of efficacy. Further studies are needed to establish and implement effective retention strategies to improve compliance with and, thus, the efficacy of self-managed internet-based interventions.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"20533691251352044"},"PeriodicalIF":0.0,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary interventions to support and improve sleep disturbances and insomnia disorder in menopause: From bench to bedside. 饮食干预支持和改善更年期睡眠障碍和失眠症：从实验室到床边。

Post reproductive health Pub Date : 2025-06-01 Epub Date: 2025-07-02 DOI: 10.1177/20533691251350518

Rosie H Musgrave, Sara Nowakowski, Tamlyn J Watermeyer, Emily J Arentson-Lantz, Greg J Elder

{"title":"Dietary interventions to support and improve sleep disturbances and insomnia disorder in menopause: From bench to bedside.","authors":"Rosie H Musgrave, Sara Nowakowski, Tamlyn J Watermeyer, Emily J Arentson-Lantz, Greg J Elder","doi":"10.1177/20533691251350518","DOIUrl":"10.1177/20533691251350518","url":null,"abstract":"Sleep is essential for maintaining physical and psychological health, and also cognitive health (referred to as 'brain health'). However, the transition to menopause has a direct impact upon sleep. Sleep disturbances are reported by approximately 40%-60% of menopausal women, and insomnia disorder is also prevalent. Diet-based interventions could potentially be used to improve subjective sleep quality in this population, and although there are several promising interventions which have been used in other groups that could be trialled, the evidence base is currently lacking. One particularly promising area for future research is that these interventions might be used alongside, or instead of, established treatments for insomnia disorder. This may also help to prevent the development of longer-term insomnia disorder. Future studies should use well-controlled, adequately powered, clinical trial designs to assess the effectiveness of dietary interventions in improving subjective sleep quality, treating insomnia disorder, and preventing acute sleep disturbances from progressing to chronic insomnia. Given the strong association between sleep and neurodegeneration, optimizing sleep in menopausal women, using targeted diet-based strategies, may have significant implications for brain health.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":"31 2","pages":"122-126"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The gut microbiota in menopause: Is there a role for prebiotic and probiotic solutions? 绝经期的肠道微生物群：益生元和益生菌解决方案是否有作用？

Post reproductive health Pub Date : 2025-06-01 Epub Date: 2025-05-07 DOI: 10.1177/20533691251340491

Marrium Liaquat, Anne Marie Minihane, David Vauzour, Matthew G Pontifex

{"title":"The gut microbiota in menopause: Is there a role for prebiotic and probiotic solutions?","authors":"Marrium Liaquat, Anne Marie Minihane, David Vauzour, Matthew G Pontifex","doi":"10.1177/20533691251340491","DOIUrl":"10.1177/20533691251340491","url":null,"abstract":"The gut microbiota, comprising a diverse array of microorganisms in the gastrointestinal tract, has emerged as a key player in human health. Emerging research indicates that this gut microbial composition is influenced by sex. These sex differences are not necessarily static and likely alter across the life course in response to several factors including changing hormone profile. As such, the menopause transition-a pivotal phase in female ageing in which the hormone profile changes dramatically is receiving increasing attention. Declining estrogen which occurs during menopause appears to influence the microbiota, which may in turn contribute to menopause-related conditions such as weight gain, bone health, cancer risk and cognitive health. The modulation of estrogen through the gut's 'estrobolome', a collection of bacterial genes involved in estrogen metabolism, may offer explanation for some of the interindividual differences observed during menopause (e.g. length, symptoms and disease risk). Therapeutic modulation of the gut microbiota therefore represents a potential approach towards managing menopausal symptoms. Indeed, prebiotics and probiotics such as Lactobacillus have been shown to increase bacterial diversity and improve metabolic and overall health in menopausal women. However, evidence remains limited regarding the specific underlying mechanisms, highlighting an urgent need for a research focus in the area. This review summarizes the current understanding of the gut microbiota's role in menopausal health and the potential of prebiotics and probiotics as therapeutic interventions. Further research into gut microbiota modulation may enable more effective, personalised treatments for menopause-associated health challenges, and supporting women's health into older ages.","PeriodicalId":52104,"journal":{"name":"Post reproductive health","volume":" ","pages":"105-114"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary patterns and their associations with body composition, cardiometabolic and bone health in postmenopausal women. 绝经后妇女的饮食模式及其与身体组成、心脏代谢和骨骼健康的关系

Post reproductive health Pub Date : 2025-06-01 Epub Date: 2025-05-02 DOI: 10.1177/20533691251339566

Nicola Best

引用次数: 0