Impact of hormonal replacement therapy on menopausal women with psychosis: A literature review.

Q3 Medicine
Nora Shero, Valérie Giroux
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引用次数: 0

Abstract

IntroductionRecent literature has explored the use of hormone replacement therapy (HRT) in menopausal women experiencing psychosis. Menopause women with previous psychotic events in their lifetime experience psychotic symptoms at later peak due to the low estrogen production in their bodies, known as menopause-associated psychosis, which can potentially be improved with the help of HRT. This review aims to discuss the effects of HRT on menopausal women with psychosis by comparing studies with combination of antipsychotic drugs.MethodsA literature review using Ovid Medline search was used.ResultsThese results indicate that HRT may have a positive impact on mood and cognition to decrease the expression of psychotic signs. Some estrogen-derived treatments, such as SERM (selective estrogen receptor modulator), might also improve the impact of the antipsychotics, giving the possibility of dosage reduction and fewer side effects.ConclusionSince the management of psychosis is challenging in menopausal women due to hormonal change and antipsychotic adjustment dosage, interdisciplinary management involving psychiatry, gynecology, and family medicine specialities is crucial. This approach can manage the hormonal, psychiatric, and overall medical issues of these patients, provide better psychiatric care, and improve their quality of life. Further research should validate the HRT protocols along with the enhancement of the technique when used in combination with antipsychotic drugs.

激素替代疗法对绝经期精神病妇女的影响:文献综述。
最近的文献探讨了激素替代疗法(HRT)在绝经期精神病妇女中的应用。绝经期妇女一生中有过精神病事件,由于体内雌激素分泌较低,在后期出现精神病症状,称为更年期相关精神病,可以在激素替代疗法的帮助下得到改善。本综述旨在通过比较HRT与联合抗精神病药物的研究来讨论HRT对绝经期精神病妇女的影响。方法采用Ovid Medline检索进行文献回顾。结果HRT可能对患者的情绪和认知有积极的影响,从而减少精神病症状的表达。一些雌激素衍生的治疗,如选择性雌激素受体调节剂(SERM),也可能改善抗精神病药物的效果,使剂量减少和副作用减少成为可能。结论绝经期妇女由于激素变化和抗精神病药物调整剂量的变化,精神病的管理具有挑战性,因此涉及精神病学、妇科和家庭医学的跨学科管理至关重要。这种方法可以管理这些患者的激素、精神和整体医疗问题,提供更好的精神护理,提高他们的生活质量。进一步的研究应该验证HRT方案,并加强与抗精神病药物联合使用时的技术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Post reproductive health
Post reproductive health Medicine-Obstetrics and Gynecology
CiteScore
2.50
自引率
0.00%
发文量
31
期刊介绍: Post Reproductive Health (formerly Menopause International) is a MEDLINE indexed, peer reviewed source of news, research and opinion. Aimed at all those involved in the field of post reproductive health study and treatment, it is a vital resource for all practitioners and researchers. As the official journal of the British Menopause Society (BMS), Post Reproductive Health has a broad scope, tackling all the issues in this field, including the current controversies surrounding postmenopausal health and an ageing and expanding female population. Initially this journal will concentrate on the key areas of menopause, sexual health, urogynaecology, metabolic bone disease, cancer diagnosis and treatment, recovering from cancer, cardiovascular disease, cognition, prescribing, use of new hormone therapies, psychology, the science of ageing, sociology, economics, and quality of life. However as a progressive and innovative journal the Editors are always willing to consider other areas relevant to this rapidly expanding area of healthcare.
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