JPEN. Journal of parenteral and enteral nutrition最新文献

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Nutritional intake adequacy, muscle mass, strength, and sarcopenia in adults on hemodialysis in Panama: A descriptive cross-sectional study. 巴拿马成人血液透析患者的营养摄入充足性、肌肉质量、力量和肌肉减少症:一项描述性横断面研究。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-09-20 DOI: 10.1002/jpen.70143
Mónica Montenegro, Ruth Ávila, Rossana Broce, Mayte Batista, María Vergara, Alieth Sáez, Victoria Rodríguez, Adilia Gómez González, Eyleen Montero Romero, Israel Barría, Otilda M Valderrama V
{"title":"Nutritional intake adequacy, muscle mass, strength, and sarcopenia in adults on hemodialysis in Panama: A descriptive cross-sectional study.","authors":"Mónica Montenegro, Ruth Ávila, Rossana Broce, Mayte Batista, María Vergara, Alieth Sáez, Victoria Rodríguez, Adilia Gómez González, Eyleen Montero Romero, Israel Barría, Otilda M Valderrama V","doi":"10.1002/jpen.70143","DOIUrl":"https://doi.org/10.1002/jpen.70143","url":null,"abstract":"<p><strong>Background: </strong>Malnutrition and sarcopenia are highly prevalent among patients on hemodialysis, leading to reduced functional capacity, impaired quality of life, and increased mortality. Despite its relevance, nutritional and muscle health assessments remain limited in routine dialysis care, particularly in resource-limited health systems. Our study aimed to evaluate nutritional intake adequacy and muscle health indicators in adults receiving maintenance hemodialysis.</p><p><strong>Methods: </strong>We performed a descriptive cross-sectional study in 105 adults receiving maintenance hemodialysis (January-July 2025). Dietary intake was assessed with a single 24-h dietary recall. Muscle health was evaluated using skeletal muscle mass index, phase angle, calf circumference, and handgrip strength.</p><p><strong>Results: </strong>Median energy and protein intakes were 17.0 kcal/kg/day and 0.8 g/kg/day, with 89.5% and 79.0% of participants consuming <80% of requirements. Sarcopenia was present in 22.9% of participants (31.6% women vs. 17.9% men, p = 0.17) and was significantly associated with severely reduced body-mass-index-adjusted calf circumference (OR 7.1, 95% CI 2.3, 22.3). Calf circumference correlated positively with the skeletal muscle mass index (r = 0.37, p < 0.001). The standardized phase angle was low on 62.9% of participants, and significantly lower in those with sarcopenia [-3.3 (1.5) vs. -1.8 (2.5); p = 0.003], correlating with handgrip strength (r = 0.26, p = 0.009). Dialysis vintage was not associated with sarcopenia or dietary adequacy.</p><p><strong>Conclusion: </strong>Hemodialysis patients in a Latin American public health setting showed markedly inadequate energy and protein intake, high prevalence of sarcopenia, and reduced phase angle. Routine assessment of muscle health may provide a feasible and comprehensive approach to guide nutritional interventions and improve outcomes.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149013524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous lipid emulsions with or without fish oil for the prevention of liver disease in VLBW neonates: A network meta-analysis. 静脉注射含或不含鱼油的脂质乳预防VLBW新生儿肝脏疾病:一项网络荟萃分析
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-09-16 DOI: 10.1002/jpen.70145
Maria Di Chiara, Giovanni Boscarino, Gianluca Terrin
{"title":"Intravenous lipid emulsions with or without fish oil for the prevention of liver disease in VLBW neonates: A network meta-analysis.","authors":"Maria Di Chiara, Giovanni Boscarino, Gianluca Terrin","doi":"10.1002/jpen.70145","DOIUrl":"10.1002/jpen.70145","url":null,"abstract":"<p><strong>Background: </strong>Parenteral nutrition-associated liver disease is a severe complication in very low birth weight (≤1500 g) preterm neonates. Although previous pairwise meta-analyses have compared individual intravenous lipid emulsions, their relative efficacy across all available formulations has not been established in this population.</p><p><strong>Methods: </strong>We conducted a systematic review and frequentist random-effects network meta-analysis, searching PubMed, Embase, and the Cochrane Central Register through April 2026. Eligible studies were randomized trials of any intravenous lipid emulsion in very low birth weight neonates reporting this outcome. Treatments formed seven nodes; odds ratios versus soybean oil were estimated, ranking used the surface under the cumulative ranking curve (Bayesian model), and certainty was assessed with the Confidence in Network Meta-Analysis framework.</p><p><strong>Results: </strong>A total of 15 trials (1876 neonates) were included. Fish oil/olive oil/soybean oil was the only formulation significantly associated with reduced disease versus soybean oil (odds ratio, 0.099; 95% confidence interval, 0.016-0.613), but derived from a single high-risk-of-bias study. A soybean oil, medium-chain triglyceride, olive oil, and fish oil emulsion showed a nonsignificant reduction (odds ratio, 0.695; 0.440-1.099; 94% Bayesian probability of benefit), most pronounced among extremely low birth weight infants (odds ratio, 0.557; 0.307-1.010). In the ranking, fish oil/olive oil/soybean oil ranked first and this multicomponent emulsion second. No heterogeneity or inconsistency was detected; certainty was low to very low.</p><p><strong>Conclusion: </strong>Fish oil-containing emulsions show a consistent signal toward reduced disease in very low birth weight neonates, but evidence remains insufficient for definitive recommendations. Adequately powered trials with standardized cholestasis definitions are needed.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148979295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of early parenteral nutrition versus enteral nutrition alone on all-cause mortality in critically ill adults: A systematic review and meta-analysis. 早期肠外营养与单独肠内营养对危重成人全因死亡率的影响:一项系统回顾和荟萃分析。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-09-06 DOI: 10.1002/jpen.70140
Yi-Xuan Cai, Jiao-Tong Bao, Xin-Yi Yin, Xi Yang, Wen-Ya Wang, Ai-Ran Liu
{"title":"Effect of early parenteral nutrition versus enteral nutrition alone on all-cause mortality in critically ill adults: A systematic review and meta-analysis.","authors":"Yi-Xuan Cai, Jiao-Tong Bao, Xin-Yi Yin, Xi Yang, Wen-Ya Wang, Ai-Ran Liu","doi":"10.1002/jpen.70140","DOIUrl":"10.1002/jpen.70140","url":null,"abstract":"<p><strong>Background: </strong>While early enteral nutrition (EN) is standard for critically ill patients with functional gastrointestinal tracts, parenteral nutrition (PN) is needed when EN is contraindicated or insufficient. Optimal PN timing/selection remains controversial. This meta-analysis evaluated the impact of early PN on mortality and clinical outcomes in critically ill adults.</p><p><strong>Methods: </strong>We searched PubMed, Web of Science, Embase, and the Cochrane Library for randomized controlled trials (RCTs) published from January 2000 up to January 2025 comparing PN (total or supplemental) with EN alone in critically ill adults. The primary outcome was all-cause mortality. Risk of bias was evaluated via the Cochrane Risk of Bias 2.0 tool, and evidence quality was graded using the grading of recommendations assessment, development and evaluation (GRADE) framework. The study was registered in international prospective register of systematic reviews (PROSPERO) (CRD42023462386).</p><p><strong>Results: </strong>Twenty RCTs enrolling 12,865 patients were included. Early PN yielded comparable 30-day (risk ratio [RR] 0.96, 95% confidence interval [CI] 0.90-1.03, P = 0.29) and 90-day all-cause mortality (RR 0.95, 95% CI 0.86-1.04, P = 0.26) relative to EN alone. However, PN was associated with lower ICU mortality (RR 0.92, 95% CI 0.86-0.99, P = 0.03), shorter mechanical ventilation duration, and reduced gastrointestinal intolerance. Conversely, PN increased the risk of overall infections (RR 1.12, P = 0.002) and bloodstream infections (RR 1.27, P = 0.005).</p><p><strong>Conclusion: </strong>In critically ill adults, early PN was associated with reduced ICU mortality and mechanical ventilation duration, as well as lower gastrointestinal intolerance, but it was also associated with an increased risk of infections, notably bloodstream infections. Individualized PN strategy with rigorous infection control is warranted when EN alone is insufficient.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probiotics and intestinal permeability in adults with metabolic dysfunction-associated steatohepatitis: A secondary analysis of a randomized clinical trial. 成人代谢功能障碍相关脂肪性肝炎患者的益生菌和肠道通透性:一项随机临床试验的二次分析
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-09-06 DOI: 10.1002/jpen.70144
Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva-Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe-Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba
{"title":"Probiotics and intestinal permeability in adults with metabolic dysfunction-associated steatohepatitis: A secondary analysis of a randomized clinical trial.","authors":"Bruna Concheski de Moura, Samanta Catherine Ferreira, Amanda Souza Silva-Sperb, Helena Abadie Moraes, Larisse Longo, Carolina Uribe-Cruz, Matheus Truccolo Michalczuk, Themis Reverbel da Silveira, Carlos Thadeu Schmidt Cerski, Mário Reis Álvares da Silva, Valesca Dall'Alba","doi":"10.1002/jpen.70144","DOIUrl":"https://doi.org/10.1002/jpen.70144","url":null,"abstract":"<p><strong>Background: </strong>Metabolic dysfunction-associated steatohepatitis (MASH) is associated with altered intestinal permeability, allowing microbial products to translocate to the liver via the enterohepatic circulation and contributes to disease progression. The aim of our study was to evaluate the association between probiotic supplementation and serum claudin-3 levels in patients with MASH.</p><p><strong>Methods: </strong>We conducted a secondary analysis of a randomized, double-blind, placebo-controlled trial including adult outpatients with biopsy-confirmed MASH (Activity Score >4). Participants received either a probiotic mixture (Lactobacillus acidophilus, L. rhamnosus, L. paracasei, Bifidobacterium animalis subsp. lactis; 1 × 10<sup>9</sup> CFU or placebo (2 sachets/day) for 24 weeks. Serum claudin-3 levels and dietary intake were assessed before and after the intervention. Changes were analyzed using Generalized Estimating Equations.</p><p><strong>Results: </strong>Forty-four patients completed the trial. Baseline claudin-3 concentrations were similar between groups. After 24 weeks, serum claudin-3 levels significantly decreased in both the probiotic (14.7 to 6.1 ng/mL) and placebo groups (16.7 to 6.0 ng/mL), with no significant between-group difference. Both groups reported reduced intake of calories, carbohydrates, proteins, and fats, but no differences in weight or waist circumference.</p><p><strong>Conclusion: </strong>In conclusion, serum claudin-3 levels decreased significantly over the 24-week study period in patients with MASH. However, probiotic supplementation did not result in additional reductions in intestinal permeability compared to placebo.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between intake of vitamins E and A and serum concentrations in preterm infants: A retrospective cohort study. 早产儿维生素E和A摄入量与血清浓度之间的关系:一项回顾性队列研究。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-09-03 DOI: 10.1002/jpen.70141
A Bronnert, L Kremer, J E Harding, F H Bloomfield, B E Cormack
{"title":"Associations between intake of vitamins E and A and serum concentrations in preterm infants: A retrospective cohort study.","authors":"A Bronnert, L Kremer, J E Harding, F H Bloomfield, B E Cormack","doi":"10.1002/jpen.70141","DOIUrl":"https://doi.org/10.1002/jpen.70141","url":null,"abstract":"<p><strong>Background: </strong>Infants in neonatal intensive care are at risk of both deficiency and excess of fat-soluble vitamins, particularly E and A, due to limited reserves and the need for prolonged intravenous nutrition. We aimed to determine the effects of increased intravenous vitamin intake and to characterise the relationships between vitamin intake and serum concentrations.</p><p><strong>Methods: </strong>Retrospective cohort of infants admitted to neonatal intensive care who had serum vitamin E or A concentrations quantified in the hospital laboratory using high-performance liquid chromatography. Associations between vitamin intakes, serum concentrations, neonatal outcomes, and maternal ethnicity were explored.</p><p><strong>Results: </strong>Longer duration of intravenous nutrition was associated with higher serum concentrations of vitamin E (Spearman's ρ = 0.45, p < 0.001), but not vitamin A (ρ = 0.01, p = 0.93). Enteral vitamin intake from supplements was not associated with serum concentrations. Necrotising enterocolitis was associated with prolonged intravenous nutrition and may be a risk factor for high serum vitamin E. High vitamin E may be a risk factor for gastrointestinal bleeding. No differences in morbidity, mortality, or vitamin intake were observed between ethnicity groups.</p><p><strong>Conclusion: </strong>Serum vitamin A and E concentrations in neonatal intensive care infants did not consistently reflect intakes. Prolonged intravenous nutrition increases the risk of high serum vitamin E concentrations. Prospective studies are needed to clarify these risks and to inform targeted formulation of intravenous vitamin products for preterm infants.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enteral nutrition usage in critically ill children: A descriptive cohort study. 危重儿童肠内营养的使用:一项描述性队列研究。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-09-02 DOI: 10.1002/jpen.70142
Kaitlin Berris, Srinivas Murthy, Qian Zhang, Tanvir Jassal, Jennifer Ying, Rajavel Elango
{"title":"Enteral nutrition usage in critically ill children: A descriptive cohort study.","authors":"Kaitlin Berris, Srinivas Murthy, Qian Zhang, Tanvir Jassal, Jennifer Ying, Rajavel Elango","doi":"10.1002/jpen.70142","DOIUrl":"https://doi.org/10.1002/jpen.70142","url":null,"abstract":"<p><strong>Background: </strong>Children admitted to pediatric intensive care units requiring nutrition support receive enteral nutrition formula. Guidelines recommend concentrated formula in fluid restriction, meet 2/3 estimated energy need, a minimum 1.5 g/kg/day dietary protein and dietary recommended intakes for micronutrients. The objective of this retrospective cohort study was to compare nutrition delivery in critically ill children 1-18 years against current guidelines.</p><p><strong>Methods: </strong>Three years of charts were included over two cohorts: September 2018 to December 2020 and February 2022 to March 2023. The first cohort included demographics and nutrient intake, while the second included feeding interruption details. Logistic and linear regression models were employed to assess associations of macro-nutrient and micro-nutrient intake with age and formula type. Pearson correlations examined relationship between interruption hours and energy goal.</p><p><strong>Results: </strong>Children (n = 86) that were included spanned 459 nutrition support days. Concentrated formula was provided in 34% of nutrition support days, goal of 2/3 estimated energy need met in 43.9% and 24.9% met minimum protein intake. Micronutrients were mostly met with prescribed volumes; however, vitamin D and selenium intakes were inadequate in pediatric formula products. Length of interruptions was 5 h per day with an average of two interruptions.</p><p><strong>Conclusion: </strong>Nutrient intake recommendations are unable to be met in critically ill children when comparing one enteral nutrition formula product against multiple different age group recommendations. The age ranges for formula use needs to be reviewed on an institutional basis with strong consideration of concentrate products.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148883279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between preoperative malnutrition and hospital length of stay in adults with major lung resection: A prospective cohort study. 成人大肺切除术术前营养不良与住院时间的关系:一项前瞻性队列研究
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-08-23 DOI: 10.1002/jpen.70138
Paola Renata Lamoyi-Domínguez, Nadia Carolina Rodríguez-Moguel, Valeria Alanis-Toledo, Diego Emiliano Chávez-Fernández, Héctor Olvera-Prado, Oscar Francisco Silva-Gómez, Diana Elizabeth García-Campos, Graciela Hernández-Silva, Ricardo Elí Guido-Guerra, Sebastian Rodríguez-Llamazares, Carmen Margarita Hernández-Cardenas, Iván Armando Osuna-Padilla
{"title":"Association between preoperative malnutrition and hospital length of stay in adults with major lung resection: A prospective cohort study.","authors":"Paola Renata Lamoyi-Domínguez, Nadia Carolina Rodríguez-Moguel, Valeria Alanis-Toledo, Diego Emiliano Chávez-Fernández, Héctor Olvera-Prado, Oscar Francisco Silva-Gómez, Diana Elizabeth García-Campos, Graciela Hernández-Silva, Ricardo Elí Guido-Guerra, Sebastian Rodríguez-Llamazares, Carmen Margarita Hernández-Cardenas, Iván Armando Osuna-Padilla","doi":"10.1002/jpen.70138","DOIUrl":"10.1002/jpen.70138","url":null,"abstract":"<p><strong>Background: </strong>Postoperative infections remain a frequent complication after lung resection, and malnutrition is highly prevalent in this population. However, evidence on the impact of malnutrition on clinical outcomes following major lung surgery is limited. This study evaluated the association between preoperative malnutrition and hospital length of stay and postoperative infections in patients undergoing lung resection.</p><p><strong>Methods: </strong>A prospective cohort study was conducted. Nutritional status was assessed preoperatively using the seven-point Subjective Global Assessment (7p-SGA), classifying patients as malnourished or normal nutritional status. Body composition was measured by bioelectrical impedance analysis, and muscle function by handgrip strength. The primary outcome was hospital length of stay and postoperative infection the secondary outcome. Multivariable regression models were used.</p><p><strong>Results: </strong>A total of 62 patients were included; 61.2% were classified as malnourished. Despite comparable body mass index and no significant differences in fat-free mass index or handgrip strength overall, malnourished patients had a significantly longer hospital length of stay than normal nutritional status patients (median 7 vs 4.5 days, P = 0.01). After adjustment, malnutrition was independently associated with increased hospital length of stay in patients undergoing lung resection for infectious disease (β = 4.2 days). Postoperative infections occurred in 23% of patients; malnutrition was associated with a higher adjusted risk of infection (OR = 7.0, 95% CI: 1.3, 36.2, P = 0.02).</p><p><strong>Conclusion: </strong>Preoperative malnutrition is highly prevalent among patients undergoing lung resection and is independently associated with prolonged hospitalization and increased postoperative infection risk. Early nutritional screening and targeted interventions may improve postoperative outcomes in this high-risk population.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Survival of individuals with neurological and oncological diseases receiving home enteral nutrition: A descriptive cohort study. 接受家庭肠内营养的神经和肿瘤疾病患者的生存率:一项描述性队列研究。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-08-20 DOI: 10.1002/jpen.70139
Giuliane de Matos Wrobel, Cesar Augusto Taconeli, Rubia Daniela Thieme, Maria Eliana Madalozzo Schieferdecker
{"title":"Survival of individuals with neurological and oncological diseases receiving home enteral nutrition: A descriptive cohort study.","authors":"Giuliane de Matos Wrobel, Cesar Augusto Taconeli, Rubia Daniela Thieme, Maria Eliana Madalozzo Schieferdecker","doi":"10.1002/jpen.70139","DOIUrl":"10.1002/jpen.70139","url":null,"abstract":"<p><strong>Introduction: </strong>Home enteral nutrition is mainly indicated for individuals with neurological or oncological diseases. However, few studies have evaluated survival in this population in low- and middle-income countries.</p><p><strong>Objective: </strong>To investigate factors influencing survival in individuals receiving home enteral nutrition and to identify variables associated with hospital readmission and return to oral feeding during follow-up in a nutritional care program.</p><p><strong>Methods: </strong>Descriptive cohort study including adults (≥18 years) enrolled in the Nutritional Care Program for Individuals with Special Dietary Needs in Curitiba, Brazil (2006-2015). Individuals exclusively receiving home enteral nutrition, with neurological or oncological diseases, were analyzed considering demographic, clinical, nutritional, functional variables, and comorbidities. Weibull regression was used to analyze survival time; logistic regression for return to oral feeding; and quasi-Poisson regression for the frequency of hospital readmission.</p><p><strong>Results: </strong>A total of 1,000 individuals were included. Most were older adults (68.9%), bedridden (60.6%), and had neurological conditions (62.8%). Median duration of home enteral nutrition was 153 days (1-3,378). Shorter survival was associated with older age, male sex, food-based diets, nasogastric tube use, and multiple comorbidities (p < 0.05). Longer survival and return to oral feeding were associated with neurological diagnosis, preserved functional status, and use of a mixed diet (p < 0.05). Hospital readmissions were more frequent among individuals with neurological disease, longer duration of home enteral nutrition, more comorbidities, and mixed diet use (p < 0.05).</p><p><strong>Conclusion: </strong>Clinical, nutritional, and functional factors significantly influence survival and outcomes in individuals receiving home enteral nutrition, highlighting the importance of individualized monitoring and home care planning.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148805343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-FODMAP diet for pediatric patients with disorders of gut-brain interaction: A systematic review and meta-analysis. 低fodmap饮食对小儿肠脑相互作用障碍的治疗:一项系统综述和荟萃分析。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-08-17 DOI: 10.1002/jpen.70135
Pedro Henrique Silva de Oliveira Souza, João Ricardo Coutinho Coêlho, Alexandre Machado de Andrade, Kauã Santana Marques, Vitor Engrácia Valenti, Fabrício Dos Santos Menezes, Natascha Silva Sandy
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引用次数: 0
JPEN Journal Club 103. Mixed methods systematic reviews. 日本笔会杂志俱乐部混合方法系统评价。
IF 4.1
JPEN. Journal of parenteral and enteral nutrition Pub Date : 2026-08-15 DOI: 10.1002/jpen.70134
Ronald L Koretz
{"title":"JPEN Journal Club 103. Mixed methods systematic reviews.","authors":"Ronald L Koretz","doi":"10.1002/jpen.70134","DOIUrl":"https://doi.org/10.1002/jpen.70134","url":null,"abstract":"","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148761331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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