JPEN. Journal of parenteral and enteral nutrition最新文献

{"title":"Human milk storage conditions and bactericidal activity: An experimental study.","authors":"Merve Yilmaz Yeşilalan, Belma Saygili Karagöl, Deniz Yaprak, Bülent Ünay, Aylin Var, Tuğrul Hoşbul","doi":"10.1002/jpen.70096","DOIUrl":"https://doi.org/10.1002/jpen.70096","url":null,"abstract":"<p><strong>Objective: </strong>Breast milk is crucial for neonatal nutrition and provides antimicrobial protection. While breastfeeding for at least 6 months is ideal, situations may arise where stored milk is necessary. This study examines how storage in polyethylene bags and Pyrex bottles affects breast milk's antimicrobial effectiveness against common neonatal pathogens: Escherichia coli, Staphylococcus aureus, and Streptococcus agalactiae.</p><p><strong>Materials and methods: </strong>Conducted from December 15, 2023, to March 15, 2024, the prospective study involved 30 term infants and their mothers, aged 18-40, at Gülhane Training and Research Hospital. Milk was manually expressed into both container types and stored at 4°C for 0, 24, and 48 h. Bactericidal activity was evaluated using standard strains of E. coli, S. aureus, and S. agalactiae, with colony counts analyzed after 24 h of cultivation.</p><p><strong>Results: </strong>No significant differences were found between storage types for overall colony counts. However, S. agalactiae showed a significant increase in colonies at 48 h in Pyrex bottles (p = 0.003), while S. aureus colonies increased significantly in polyethylene bags at 48 h (p = 0.036).</p><p><strong>Conclusion: </strong>Bactericidal activity against S. agalactiae and S. aureus decreased significantly in stored milk after 24 and 48 h in the refrigerator. Short-term storage of human milk may compromise its antimicrobial properties depending on bacterial strain and container type, indicating the need for further research on optimal storage conditions.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between iron supplementation during pregnancy and delivery mode on double burden of malnutrition in South Asia: A cross-sectional survey study.","authors":"Maliha Mahazabin, Sumaya Sultana, Ijaj Ahmed, Md Shoebuj Zaman, Tohora Safa, Murfia Rahman Muna, Nahid Hasan Monna, Farhan Fuad, Khondokar Naymul Islam","doi":"10.1002/jpen.70102","DOIUrl":"https://doi.org/10.1002/jpen.70102","url":null,"abstract":"<p><strong>Background: </strong>South Asia is witnessing a rise in obesity among reproductive-aged women, and the repercussions of this condition extend to their offspring. Our research aims to assess the impact of caesarean section and iron supplementation during pregnancy on different forms of double burden of malnutrition among mother-child dyads in South Asia.</p><p><strong>Method: </strong>This study utilized cross-sectional survey data from 116,547 non-pregnant women having at least one child from Bangladesh, Nepal, Pakistan, India, and the Maldives who completed a Demographic and Health Survey from 2016-2022. A descriptive, bivariate, log-binomial regression model and population attributable fraction for analysis were also employed, with a 5% significance level.</p><p><strong>Results: </strong>Mothers who underwent caesarean delivery demonstrated a 53%, 42%, and 50% increased likelihood of being overweight/obese with stunted child, with wasted child, and with underweight child, respectively, in comparison to those who experienced vaginal delivery. Caesarean delivery without iron supplementation exhibited the highest individual risk across all categories: adjusted prevalence ratio (aPR) of 1.68 (95% CI: 1.48, 1.90) for stunted children of overweight mothers, aPR of 1.65 (95% CI: 1.39, 1.96) for wasted children of overweight mothers, and aPR of 1.79 (95% CI: 1.55, 2.06) for underweight children of overweight mothers.</p><p><strong>Conclusion: </strong>Positive population attributable fraction of the exposure highlights that the prevalence of double burden of malnutrition would be higher in the presence of caesarean delivery. Policymakers should promote awareness initiatives regarding the risk of caesarean delivery and the necessity of iron supplementation during pregnancy in South Asia.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Different approaches of SARC-tools for Sarcopenia Screening in chronic obstructive pulmonary disease: a cross-sectional validation study.","authors":"Alicia S Hartmann, João G Brum, Thiago G Barbosa-Silva, Maria C Gonzalez, Juliessa Florian, Flávia M Silva","doi":"10.1002/jpen.70099","DOIUrl":"https://doi.org/10.1002/jpen.70099","url":null,"abstract":"<p><strong>Background: </strong>We aimed to assess the concurrent and predictive validity of different screening tools for sarcopenia in outpatients with chronic obstructive pulmonary disease.</p><p><strong>Methods: </strong>Cross-sectional study with 124 community-dwelling adults with chronic obstructive pulmonary disease (67.8 ± 8.4 years, 57.6% female). SARC-F, SARC-CalF, and SARC-CalF_BMI-CC were applied; sarcopenia was diagnosed and considered as reference to test the concurrent validity. The outcomes evaluated to test the predictive validity included dyspnea severity, stage of disease, quality of life, the 6-min walk test, and the prognosis index.</p><p><strong>Results: </strong>SARC-CalF_BMI-CC presented the highest sensitivity (79.5% vs 43.2% vs 20.5%), and negative predictive value (78.6% vs 68.8% vs 66.3%) compared to SARC-CalF and SARC-F, respectively. Patients with sarcopenia risk by SARC-CalF_BMI-CC were 3.37 times (95% CI 1.18; 9.63) more likely to walk less than 350 m, 5.31 times (95% CI 2.01; 14.04) more likely to have poorer prognosis, 4.05 times (95% CI 1.55; 10.61) more likely to experience greater shortness of breath, and 6.4 times (95% CI 1.94; 21.13) more likely to have diminished quality of life. Risk of sarcopenia identified by SARC-F (advanced stage of disease, poor prognosis and quality of life) and SARC-Calf (advanced stage of disease, poor prognosis, and reduced functional capacity) was associated with a lower number of outcomes.</p><p><strong>Conclusions: </strong>SARC-CalF_BMI-CC demonstrated the highest accuracy to identify sarcopenia. Patients with sarcopenia risk by SARC-CalF_BMI-CC were more likely to present worse outcomes compared to those identified by SARC-F or SARC-Calf, suggesting the use of SARC-CalF_BMI-CC for these patients.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147849254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adjusting for inflammation and adopting post-stabilization BIA: Toward reliable mortality prediction in parenteral nutrition.","authors":"Ting Wang, Ran Zhang, Chao Zhang","doi":"10.1002/jpen.70098","DOIUrl":"https://doi.org/10.1002/jpen.70098","url":null,"abstract":"","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147826207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLIM criteria for the diagnosis of malnutrition in patients with cirrhosis: A narrative review.","authors":"Bárbara Chaves Santos, Ana Teresa Limon-Miro, Puneeta Tandon, Maria Isabel Toulson Davisson Correia, Carla M Prado, Maria Cristina Gonzalez, Lucilene Rezende Anastácio","doi":"10.1002/jpen.70095","DOIUrl":"https://doi.org/10.1002/jpen.70095","url":null,"abstract":"<p><strong>Background: </strong>This narrative review aims to describe and discuss the validity of the Global Leadership Initiative on Malnutrition (GLIM) criteria in patients with cirrhosis.</p><p><strong>Methods: </strong>The literature search was performed in PubMed and EMBASE between May and August 2024 and updated in January 2025, including original studies published in English in which patients with cirrhosis were assessed according to the GLIM framework.</p><p><strong>Results: </strong>Seventeen studies with data from 4275 patients were included. There were substantial differences in the use of the GLIM criteria among studies. Overall, the prevalence of malnutrition by the GLIM framework when all the criteria were considered ranged between 21% and 65.1% and was frequently lower when compared to the prevalence by other tools. Sensitivity and specificity of the GLIM criteria in comparison to standard tools were tested in four studies, and none achieved the minimum requirements to determine adequate concurrent validity. In contrast, the diagnosis of malnutrition by the framework demonstrated adequate predictive validity in six studies (HR/OR 2.1-7.2).</p><p><strong>Conclusion: </strong>In patients with cirrhosis, the prevalence of malnutrition is generally lower when assessed using the GLIM criteria compared with standard tools. Evidence on concurrent validity is currently limited, with existing studies showing insufficient sensitivity and specificity in relation to the Subjective Global Assessment. However, malnutrition defined by GLIM independently predicts adverse clinical outcomes in this population. Future research should focus on the current gaps and on the adequate use of the criteria to strengthen their clinical applicability in nutritional assessment and management of cirrhosis.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical tension and autophagy suppression: Unmasking the confounders in ICU muscle preservation strategies.","authors":"Yani Lou","doi":"10.1002/jpen.70093","DOIUrl":"https://doi.org/10.1002/jpen.70093","url":null,"abstract":"","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical value of nutrition screening tools in mechanically ventilated critically ill children: Clinical application considerations.","authors":"Zhichao Zhao, Ting Shen","doi":"10.1002/jpen.70094","DOIUrl":"https://doi.org/10.1002/jpen.70094","url":null,"abstract":"","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amino acid strategy in early postoperative parenteral nutrition.","authors":"Jiaqi Shen, Fangfang Huang","doi":"10.1002/jpen.70092","DOIUrl":"https://doi.org/10.1002/jpen.70092","url":null,"abstract":"","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: Timing-specific neutrality in a Rigorous ICU anabolic trial.","authors":"Lizl Veldsman, Guy A Richards, Daniel Nel, Tertius A Kohn, Renée Blaauw","doi":"10.1002/jpen.70091","DOIUrl":"https://doi.org/10.1002/jpen.70091","url":null,"abstract":"","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147719352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exclusive enteral nutrition and the risk of nonsurgical readmission in patients with Crohn's disease-related intra-abdominal abscess: A retrospective cohort study.","authors":"Zhihong Zhang, Tanxing Cai, Hao Xie, Renhan Luo, Huashan Liu, Wenxin Li, Ziwei Zeng, Zhenxing Liang, Li Xiong, Xiaosheng He, Liang Huang, Liang Kang, Xiaobin Zheng","doi":"10.1002/jpen.70090","DOIUrl":"https://doi.org/10.1002/jpen.70090","url":null,"abstract":"<p><strong>Background: </strong>Intra-abdominal abscess management in Crohn's disease patients represents a significant clinical challenge. This study sought to assess the impact of exclusive enteral nutrition on nonsurgical readmission in patients with Crohn's disease-related intra-abdominal abscess.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted between January 2016 and June 2022 included Crohn's disease patients hospitalized for intra-abdominal abscess. Patients were categorized based on exclusive enteral nutrition administration during hospital stay or not. The primary outcome was nonsurgical readmission within 1-year post-discharge. Secondary outcomes included surgical intervention and abscess recurrence. Multivariable logistic regression analysis and Cox regression analysis were performed to adjust for potential confounding factors.</p><p><strong>Results: </strong>A total of 128 patients were enrolled, with 45 allocated to the exclusive enteral nutrition group and 83 to the nonexclusive enteral nutrition group. Compared to the nonexclusive enteral nutrition group, patients treated with exclusive enteral nutrition were less likely to require nonsurgical readmissions (42.2% vs 79.5%, P < 0.001). The multivariate analysis confirmed exclusive enteral nutrition as an independent protective factor against nonsurgical readmissions (hazard ratio: 0.11; 95% confidence interval: 0.04-0.30; P < 0.001). In addition, exclusive enteral nutrition group showed a significantly lower rate of surgical intervention (46.7% vs 75.9%, P = 0.01). Notably, abscess recurrence rates remained comparable between groups.</p><p><strong>Conclusion: </strong>This study provides novel evidence that exclusive enteral nutrition is associated with reduced risks of nonsurgical readmission and surgical burden without affecting abscess recurrence rates in patients with Crohn's disease-related intra-abdominal abscess.</p>","PeriodicalId":520701,"journal":{"name":"JPEN. Journal of parenteral and enteral nutrition","volume":" ","pages":""},"PeriodicalIF":4.1,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147694823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}