Journal of investigational allergology & clinical immunology最新文献_第4页

Analysis of the Budget Impact of Fractional Exhaled Nitric Oxide Monitoring in the Management of Childhood Asthma: The Colombian National Health System Perspective. 分次呼气一氧化氮监测在儿童哮喘管理中的预算影响分析:哥伦比亚国家卫生系统的观点。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-04-13 DOI: 10.18176/jiaci.0690

J A Buendía, R Acuña-Cordero, C E Rodriguez-Martinez

{"title":"Analysis of the Budget Impact of Fractional Exhaled Nitric Oxide Monitoring in the Management of Childhood Asthma: The Colombian National Health System Perspective.","authors":"J A Buendía, R Acuña-Cordero, C E Rodriguez-Martinez","doi":"10.18176/jiaci.0690","DOIUrl":"https://doi.org/10.18176/jiaci.0690","url":null,"abstract":"Background: Fractional exhaled nitric oxide (FeNO) testing is a simple, noninvasive approach to assessing airway inflammation with minimal discomfort that provides results within a few minutes. For policy makers, the economic impact of this technology is the main concern, especially in developing countries. We evaluated the budget impact of asthma management using FeNO monitoring in patients aged between 4 and 18 years in Colombia.Methods: A budget impact analysis was performed to evaluate the potential cost of FeNO monitoring. The analysis was based on a 5-year time horizon and performed from the perspective of the Colombian National Health System. The incremental budget impact was calculated by subtracting the cost of the new treatment, in which FeNO is reimbursed, from the cost of conventional treatment without FeNO (management based on clinical symptoms [with or without spirometry/peak flow] or asthma guidelines [or both] for asthma-related cases). Univariate 1-way sensitivity analyses were performed.Results: In the base case analysis the 5-year costs associated with FeNO and non-FeNO were estimated to be €469 904 130 and €480 485 149, respectively, indicating savings for the Colombian National Health System of €10 581 019 if FeNO is adopted for the routine management of patients with persistent asthma. This result proved to be robust in the univariate 1-way sensitivity analysis.Conclusion: FeNO monitoring generated cost savings in emergency settings for infants with persistent asthma. This evidence can be used by decision makers in Colombia to improve clinical practice guidelines and should be replicated to validate the results in other middle-income countries.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"200-205"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25586787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Contact Dermatitis Caused by Glucose Sensors: More Than Allergy to Isobornyl Acrylate. 葡萄糖传感器引起的接触性皮炎:比对丙烯酸异鸟酯过敏更严重。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-09-07 DOI: 10.18176/jiaci.0739

J B Joyanes Romo, J M Borja Segade, L Moreno Lozano, R García Rodríguez, O M González Jiménez, A Palacios Cañas, J V Meneses Sotomayor, E Gómez Torrijos

引用次数: 1

Polyethylene Glycol Allergy and Immediate-Type Hypersensitivity Reaction to COVID-19 Vaccination: Case Report. COVID-19疫苗接种后聚乙二醇过敏及立即型超敏反应1例报告

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-07-26 DOI: 10.18176/jiaci.0740

M Habran, M Vandebotermet, R Schrijvers

引用次数: 15

Role of Drug Hypersensitivity in the Cutaneous Manifestations of SARS-CoV-2 Infection. 药物过敏在SARS-CoV-2感染皮肤表现中的作用

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-09-07 DOI: 10.18176/jiaci.0744

E Solano-Solares, V Chica-Guzmán, I Pérez-Allegue, R Cabrera-Hernández, M Fernández-Guarino, D Fernández-Nieto, C Moreno-García-Del-Real, A de-Andres-Martin, L García-Bermejo, D González-de-Olano, B de-la-Hoz-Caballer

引用次数: 2

DRESS Syndrome Induced by a Gadolinium-Based Contrast Agent in a 13-Year-Old Boy. 钆基造影剂致13岁男孩DRESS综合征。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-10-18 DOI: 10.18176/jiaci.0742

E M Macías-Iglesias, M V Campanón-Toro, E Moreno Rodilla, S de Arriba-Méndez, M Sobrino-García, A Gallardo-Higueras, I Dávila

引用次数: 3

Nonasthmatic Eosinophilic Bronchitis and Asthma: Analysis of Biomarkers. 非哮喘性嗜酸性支气管炎和哮喘:生物标志物分析。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-10-18 DOI: 10.18176/jiaci.0738

V Villalobos-Violan, D Betancor, I Mahíllo-Fernández, J Sastre

引用次数: 1

Effectiveness of Benralizumab in Severe Eosinophilic Asthma Under Conditions of Routine Clinical Practice. 在常规临床条件下，贝那利珠单抗治疗重度嗜酸性哮喘的有效性。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2022-02-15 DOI: 10.18176/jiaci.0793

J C Miralles López, R Andújar-Espinosa, F J Bravo-Gutiérrez, M Castilla-Martínez, I Flores-Martín, M L Alemany-Francés, M J Pajarón-Fernández, A Mora González, J Valverde-Molina, V Pérez-Fernández

{"title":"Effectiveness of Benralizumab in Severe Eosinophilic Asthma Under Conditions of Routine Clinical Practice.","authors":"J C Miralles López, R Andújar-Espinosa, F J Bravo-Gutiérrez, M Castilla-Martínez, I Flores-Martín, M L Alemany-Francés, M J Pajarón-Fernández, A Mora González, J Valverde-Molina, V Pérez-Fernández","doi":"10.18176/jiaci.0793","DOIUrl":"https://doi.org/10.18176/jiaci.0793","url":null,"abstract":"Miralles López JC, Andújar-Espinosa R, Bravo-Gutiérrez FJ, Castilla-Martínez M, Flores-Martín I, Alemany-Francés ML, Pajarón-Fernández MJ, Mora González A, Valverde-Molina J , Pérez-Fernández V, RE-ASGRAMUR GROUP Allergy Department. University General Hospital Reina Sofia. Murcia, Spain Pulmonology Department. University Clinic Hospital Virgen de la Arrixaca. Murcia, Spain Pulmonology Department. University General Hospital Santa Lucia. Cartagena, Murcia, Spain Pulmonology Department. University General Hospital Los Arcos. San Javier, Murcia, Spain Allergy Department. University General Hospital Santa Lucia. Cartagena, Murcia, Spain Pulmonology Department. University General Hospital Morales Meseguer. Murcia, Spain Allergy Department. Hospital de la Vega. Cieza, Murcia, Spain Allergy Department. University General Hospital Morales Meseguer. Murcia, Spain Paediatrics Department. University General Hospital Santa Lucia. Cartagena, Murcia, Spain Department of Public Health Sciences. University of Murcia School of Medicine. Murcia, Spain * Members of the RE-ASGRAMUR (Register of Severe Asthma of the Region of Murcia) Group are listed in Supplementary Appendix 1.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"220-223"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39925086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Nonimmediate Maculopapular Erythema Induced by a Gadolinium-Based Contrast Agent. 钆基造影剂诱发的非立即性黄斑丘疹。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-09-07 DOI: 10.18176/jiaci.0733

A Gauthier, F Mankouri, P Demoly, A M Chiriac

引用次数: 3

Unraveling the Diagnosis of Kiwifruit Allergy: Usefulness of Current Diagnostic Tests. 揭开猕猴桃过敏的诊断:当前诊断测试的有用性。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-04-08 DOI: 10.18176/jiaci.0691

C M D'Amelio, A Bernad, B E García-Figueroa, S Garrido-Fernández, J Azofra, A Beristain, C Bueno-Díaz, M Garrido-Arandia, G Gastaminza, M Ferrer, A Díaz Perales, M Villalba, M J Goikoetxea

{"title":"Unraveling the Diagnosis of Kiwifruit Allergy: Usefulness of Current Diagnostic Tests.","authors":"C M D'Amelio, A Bernad, B E García-Figueroa, S Garrido-Fernández, J Azofra, A Beristain, C Bueno-Díaz, M Garrido-Arandia, G Gastaminza, M Ferrer, A Díaz Perales, M Villalba, M J Goikoetxea","doi":"10.18176/jiaci.0691","DOIUrl":"https://doi.org/10.18176/jiaci.0691","url":null,"abstract":"Objectives: To determine the usefulness of the in vitro and in vivo methods used in the diagnosis of kiwifruit allergy and to specifically assess the impact of seed proteins on sensitivity.Methods: We performed skin prick tests (SPTs) using various commercial extracts, homemade pulp, and seed extracts and prick-prick tests with kiwifruit on 36 allergic patients. The presence of specific IgE (sIgE) was assessed using the ImmunoCAP (kiwifruit extract), ELISA (Act d 1, Act d 2), ISAC, and FABER assays. Immunoblotting of seed extract was carried out, and a single-blind oral food challenge was performed with whole seeds in seed-sensitized individuals.Results: The prick prick test with kiwifruit demonstrated the highest diagnostic capacity (81.8% sensitivity and 94.1% specificity) among the in vivo tests. The sIgE levels measured using ImmunoCAP (kiwifruit extract) showed a similar sensitivity to that of global ISAC and FABER (63.9%, 59.5%, and 58.3%, respectively). Act d 1 was the major allergen. Sensitization to Act d 1 was associated with positive sIgE results to whole kiwifruit extract detected by ImmunoCAP (P<.000). A positive SPT result to kiwifruit seeds was associated with severe symptoms induced by kiwifruit (P=.019) as a marker of advanced disease, but not with clinically relevant sensitization. Challenge testing with kiwifruit seeds performed on 8 seed-sensitized patients yielded negative results.Conclusion: Sensitization to Act d 1 is associated with a positive result in conventional diagnostic techniques, whereas kiwifruit seed sensitization does not increase the sensitivity of the diagnostic techniques evaluated.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"206-212"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25569895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Multitool Approach for High-Risk Aspirin Desensitization in a Pregnant Woman. 孕妇高危阿司匹林脱敏的多工具方法。

IF 7.2

Journal of investigational allergology & clinical immunology Pub Date : 2022-06-20 Epub Date: 2021-10-18 DOI: 10.18176/jiaci.0734

E Pérez Rodríguez, H A Martínez Tadeo, G Hernández Santana, F J Iglesias Souto, E Rodríguez Plata, J Barrios Recio, A Callero Viera

引用次数: 1