Journal of investigational allergology & clinical immunology最新文献

{"title":"Generalized Urticaria Caused by a Glycerin Enema in an Infant.","authors":"N Kajita, K Kanamori, S Yamamoto, K Yoshida","doi":"10.18176/jiaci.0760","DOIUrl":"https://doi.org/10.18176/jiaci.0760","url":null,"abstract":"","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"318-319"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39625887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Allergy to Beer and Wine Caused by Saccharomyces cerevisiae in a Patient Sensitized to Fungi.","authors":"A German-Sanchez, A Alonso-Llamazares, F Garcia-Gonzalez, B Matala-Ahmed, B Bartolome-Zavala, I Antepara-Ercoreca","doi":"10.18176/jiaci.0755","DOIUrl":"https://doi.org/10.18176/jiaci.0755","url":null,"abstract":"J Investig Allergol Clin Immunol 2022; Vol. 32(4): 304-323 © 2022 Esmon Publicidad The presence of potential barley allergens and proteins from S cerevisiae have been described in beer through proteomic studies (nonspecific lipid transfer protein [nsLTP], gliadins, glutelins, trypsin a-amylase inhibitors, serpins) [3,4], and some have been shown to trigger allergic reactions, as follows: nsLTP (9 kDa), protein Z (45 kDa) [5], and protein Z–type serpin (20-25 kDa) [6]. Similarly, sensitization to yeast [7] has been described as the cause of allergy to beer, cider, and wine. The patient was a 33-year-old woman with a personal history of allergic rhinoconjunctivitis and exercise-induced asthma who had been experiencing episodes of anaphylaxis (ocular pruritus, eyelid angioedema, globus sensation, dysphonia, diarrhea, urticaria, and dizziness) with no associated exercise over a period of 3 years. These reactions resolved with self-administered epinephrine. She related the episodes to ingestion of beer with chips or olives. Occasionally, she had experienced milder symptoms after drinking red and white wine. She tolerates other alcoholic beverages, cereals (including bread), grapes, nuts, and all kinds of food. Protein extracts from various brands of beer (Heineken, San Miguel, Chimay, Franziskaner) were prepared by homogenization in phosphate-buffered saline (50% vol/vol) (50 mM phosphate buffer, 100 mM NaCl, pH 7.5), dialyzation against distilled water, and lyophilization. As some beers are produced with wheat, 1 of the beers studied was a wheat beer (Franziskaner). Skin prick tests (SPTs) with common aeroallergens (pollens, dust mites, molds, pet dander) were positive to Allergy to Beer and Wine Caused by Saccharomyces cerevisiae in a Patient Sensitized to Fungi","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"311-313"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39527741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Desensitization to Pertuzumab With a Positive Skin Test Result in a Mixed-Phenotype Hypersensitivity Reaction.","authors":"J A Lemus Calderón, G Tapia de Pedro, E Marchan Martín, R Guzmán Rodriguez, M N Cabañes Higuero, C J Senent Sánchez","doi":"10.18176/jiaci.0761","DOIUrl":"https://doi.org/10.18176/jiaci.0761","url":null,"abstract":"","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"320-321"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39625890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Salmonella Infections and Nephritis Complicating IgA Vasculitis in a Patient with IL-12Rβ1 Deficiency.","authors":"L Blancas-Galicia, A K Peñafiel-Vicuña, S Scheffler-Mendoza, M Rojas-Maruri, F Rivas-Larrauri, A L Rodríguez-Lozano, J Bustamante, M A Yamazaki-Nakashimada","doi":"10.18176/jiaci.0750","DOIUrl":"https://doi.org/10.18176/jiaci.0750","url":null,"abstract":"vasculitis.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"308-310"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39389993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eosinophilic Esophagitis Caused by Grass Pollen Sublingual Immunotherapy With Tolerance to a Subcutaneous Extract.","authors":"F Skrabski, M E Pérez-Pallisé, A Domínguez Estirado, C López Tovar, A Bermejo-Becerro, E Rodríguez Mazariego, J M Zubeldia, A Prieto García","doi":"10.18176/jiaci.0759","DOIUrl":"https://doi.org/10.18176/jiaci.0759","url":null,"abstract":"1. James C, Bernstein DI. Allergen immunotherapy: an updated review of safety. Curr Opin Allergy Clin Immunol. 2017;17(1):55-9. 2. Bernstein H, Shupack J, Ackerman AB. Cutaneous Pseudolymphoma resulting from Antigen Injections. Arch Dermatol. 1974;110:756-7. 3. Cerroni L, Borroni RG, Massone C, Chott A, Kerl H. Cutaneous B-cell Pseudolymphoma at the site of vaccination. Am J Dermatopathol. 2007;29:538-42 4. Maubec E, Pinquier L, Viguier M, Caux F, Amsler E, Aractingi S, et al. Vaccination-induced cutaneous pseudolymphoma. J Am Acad Dermatol. 2005;52:623-9. 5. Goerdt S, Spieker T, Wölffer LU. Multiple cutaneous B-cell pseudolymphomas after allergen injections. J Am Acad Dermatol. 1996;34:1072-4. 6. Hernández I, Sanmartín O, Cardác C, Gómez S, Alfaro A. Pseudolinfoma B inducido por hidróxido de aluminio tras tratamiento hiposensibilizante. Actas Dermosifiliogr. 2008;99:213-6. 7. Staser K, Abner S, Anadkat M, Musiek A, Schaffer A. Injection-Site Cutaneous Pseudolymphoma Induced by a GM-CSF–Producing Tumor Cell Vaccine. JAMA Dermatology. 2017;153:332-3. 8. Bi X, Liu Y, He M, Gu J. Peripheral T-cell lymphoma at the injection site of influenza vaccination. Indian J Dermatol Venereol Leprol. 2014;80:526-9. 9. Chandler JB, Waldman R, Sloan SB, Rose MG, Wong EY. Cutaneous marginal zone lymphoma following anthrax vaccination. Ann Hematol. 2021;100(12):3079-80. 10. Mendez Diaz Y, García-Arpa M, Parra Cubillos A, De Lara Simón IM, García Rodríguez R, Gómez Torrijos E. J Investig Allergol Clin Immunol. 2018;28:199-201.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"315-317"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39527748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous B-cell Lymphoma at the Injection Site of Airborne Allergen Immunotherapy: Progression to Cutaneous Metastasis.","authors":"L Moreno Lozano, M P Sánchez Caminero, M García Arpa, Y Mendez Díaz, O M Gonzalez Jiménez, J B Joyanes Romo, A Palacios Cañas, R García Rodríguez","doi":"10.18176/jiaci.0758","DOIUrl":"https://doi.org/10.18176/jiaci.0758","url":null,"abstract":"","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"313-315"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39527747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Adherence to Treatment in Nasal Polyposis.","authors":"M Valverde-Monge, B Barroso, L Ortega-Martin, D Betancor, J Santillan, J M Villacampa, J Sastre","doi":"10.18176/jiaci.0752","DOIUrl":"https://doi.org/10.18176/jiaci.0752","url":null,"abstract":"Valverde-Monge M1,2*, Barroso B1,2*, Ortega-Martin L1, Betancor D1, Santillan J3, Villacampa JM3, Sastre J1,2 1Department of Allergy, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain 2Department of Medicine, Universidad Autónoma de Madrid, Madrid, Spain, CIBERES, Instituto de Salud Carlos III, Spain 3Department of Otorhinolaryngology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain *Contributed equally as first authors","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"299-301"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39392466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Onset of Nut Allergy in a Pediatric Cohort: Clinical and Molecular Patterns in the AFRUSEN Study.","authors":"M D Ibáñez-Sandin,&nbsp;P Rodríguez Del Río,&nbsp;M I Alvarado,&nbsp;B E García,&nbsp;T Garriga-Baraut,&nbsp;M Reche Frutos,&nbsp;C Escudero,&nbsp;A Ramirez Jiménez,&nbsp;L Vila,&nbsp;E M Lasa,&nbsp;C Blasco,&nbsp;E Marchán-Martin,&nbsp;A Martorell,&nbsp;S Sanchez-García,&nbsp;M Rodríguez-Álvarez,&nbsp;S Infante,&nbsp;V Rodríguez Vazquez,&nbsp;J M Olaguibel,&nbsp;M Labrador-Horrillo,&nbsp;T Carrillo","doi":"10.18176/jiaci.0696","DOIUrl":"https://doi.org/10.18176/jiaci.0696","url":null,"abstract":"<p><strong>Background and objective: </strong>Nut allergy is a growing problem, yet little is known about its onset in children. Objective: To characterize the onset of nut allergy in children in southern Europe.</p><p><strong>Methods: </strong>The study population comprised consecutive patients up to 14 years of age who visited allergy departments with an initial allergic reaction to peanut, tree nut, or seed. The allergy work-up included a clinical history, food challenge, skin prick testing, determination of whole-extract sIgE, and ImmunoCAP ISAC-112 assay.</p><p><strong>Results: </strong>Of the 271 children included, 260 were first diagnosed with nut allergy at a mean age of 6.5 years and at a mean (SD) of 11.8 (21.2) months after the index reaction. The most common culprit nuts at onset were walnut (36.5%), peanut (28.5%), cashew (10.4%), hazelnut (8.5%), pistachio (5.4%), and almond (5%). Onset of peanut allergy was more frequent in children ≤6 years and walnut in those aged >6 years (P=.032). In 65% of cases, the allergic reaction occurred the first time the patient consumed the nut, and 35% of reactions were anaphylactic. Overall, polysensitization to nuts was detected by skin prick testing in 64.9% of patients, although this rate was lower among walnut-allergic children (54.7%) and peanut-allergic children (54.1%) (P<.0001). Sensitization to 2S albumins was predominant (75%), especially Jug r 1 (52.8%), whereas sensitization to lipid transfer proteins was less relevant (37%).</p><p><strong>Conclusion: </strong>In the population we assessed, the onset of nut allergy occurred around 6 years of age, slightly later than that reported in English-speaking countries. Walnut was the main trigger, followed by peanut. 2S albumin storage proteins, especially Jug r 1, were the most relevant allergens. This study will help guide management and may contribute to preventive strategies in pediatric nut allergy.</p>","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"270-281"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38818363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of Fatal Anaphylaxis: A Systematic Review of Observational Studies.","authors":"S Perez-Codesido,&nbsp;A Rosado-Ingelmo,&nbsp;M Privitera-Torres,&nbsp;E Pérez Fernández,&nbsp;A Nieto-Nieto,&nbsp;A Gonzalez-Moreno,&nbsp;E Grifol-Clar,&nbsp;N Alberti-Masgrau,&nbsp;M A Tejedor-Alonso","doi":"10.18176/jiaci.0693","DOIUrl":"https://doi.org/10.18176/jiaci.0693","url":null,"abstract":"<p><strong>Background: </strong>Fatal anaphylaxis is very rare, with an incidence ranging from 0.5 to 1 deaths per million person-years.</p><p><strong>Objective: </strong>Based on a systematic review, we aimed to explain differences in the reported incidence of fatal anaphylaxis based on the methodological and demographic factors addressed in the various studies.</p><p><strong>Methods: </strong>We searched PubMed/MEDLINE, EMBASE, and the Web of Science for relevant retrospective and prospective cohort studies and registry studies that had assessed the anaphylaxis mortality rate for the population of a country or for an administrative region. The research strategy was based on combining the term \"anaphylaxis\" with \"death\", \"study design\", and \"main outcomes\" (incidence).</p><p><strong>Results: </strong>A total of 46 studies met the study criteria and included 16,541 deaths. The range of the anaphylaxis mortality rate for all causes of anaphylaxis was 0.002-2.51 deaths per million person-years. Fatal anaphylaxis due to food (range 0.002-0.29) was rarer than deaths due to drugs (range 0.004-0.56) or Hymenoptera venom (range 0.02-0.61). The frequency of deaths due to anaphylaxis by drugs increased during the study period (IRR per year, 1.02; 95%CI, 1.00-1.04). We detected considerable heterogeneity in almost all of the meta-analyses carried out.</p><p><strong>Conclusion: </strong>The incidence of fatal anaphylaxis is very low and differs according to the various subgroups analyzed. The studies were very heterogeneous. Fatal anaphylaxis due to food seems to be less common than fatal anaphylaxis due to drugs or Hymenoptera venom.</p>","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"245-260"},"PeriodicalIF":7.2,"publicationDate":"2022-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38874764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cluster Subanalysis of Patients With Severe Asthma Who Responded to Omalizumab.","authors":"I Dávila,&nbsp;P Campo,&nbsp;S Cimbollek,&nbsp;C Almonacid Sánchez,&nbsp;S Quirce,&nbsp;A Moreira,&nbsp;A Ramirez,&nbsp;G Soto Campos","doi":"10.18176/jiaci.0731","DOIUrl":"https://doi.org/10.18176/jiaci.0731","url":null,"abstract":"Dávila I1,2, Campo P3, Cimbollek S4, Almonacid Sánchez C5, Quirce S6,7, Moreira A8, Ramirez A8, Soto Campos G9 1Allergy Service, University Hospital of Salamanca and Institute for Biomedical Research of Salamanca (IBSAL), Salamanca, Spain 2Biomedical and Diagnosis Science Department, Salamanca University School of Medicine, Salamanca, Spain 3Allergy Unit, IBIMA-Regional University Hospital of Málaga, Málaga, Spain 4Department of Allergy, Hospital Universitario Virgen del Rocío, Sevilla, Spain 5Department of Respiratory Medicine, Ramón y Cajal Hospital, IRYCIS, Alcala de Henares University, Madrid, Spain 6Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain 7CIBER de Enfermedades Respiratorias, CIBERES, Madrid, Spain 8Novartis Farmacéutica, Barcelona, Spain 9Pneumology and Allergy Unit, Hospital Universitario de Jerez, Cádiz, Spain","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"213-215"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39467067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}