Journal of investigational allergology & clinical immunology最新文献

{"title":"Anaphylactic Shock to Mediterranean Silverside (Atherina boyeri) Caused by Nonparvalbumin Allergens.","authors":"N Giangrande, J M García-Menaya, B Bartolomé, A Fernández-Bolívar, C Cordobés-Durán, M Dotor-Lavado, M D Marcos-Fernández, P Bobadilla-González","doi":"10.18176/jiaci.0732","DOIUrl":"https://doi.org/10.18176/jiaci.0732","url":null,"abstract":"Giangrande N1, García-Menaya JM1, Bartolomé B2, FernándezBolívar A1, Cordobés-Durán C3, Dotor-Lavado M1, MarcosFernández MD4, Bobadilla-González P1 1Allergy Department, Badajoz University Hospital. Badajoz, Spain 2Research and Development Department, Roxall, Bilbao, Spain 3Allergy Department, Don Benito General Hospital, Don Benito, Spain 4Primary Health-Care Center, Pueblonuevo del Guadiana, Badajoz, Spain","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"224-226"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39392463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Salt-Dependent Aquagenic Urticaria, Challenge Test, and Histological Features: Case Report.","authors":"J Laiseca García, L Gónzalez Bravo, E Gomez de la Fuente, B Tristán Martin, C Sarró Fuentes, A Rosado","doi":"10.18176/jiaci.0735","DOIUrl":"https://doi.org/10.18176/jiaci.0735","url":null,"abstract":"J Investig Allergol Clin Immunol 2022; Vol. 32(3): 224-240 © 2022 Esmon Publicidad 8. Guillén D, Bobolea I, Calderon O, Fiandor A, Cabañas R, Heredia R, et al. Aspirin desensitization achieved after omalizumab treatment in a patient with aspirin-exacerbated urticaria and respiratory disease. J Investig Allergol Clin Immunol. 2015;25(2):133-5. 9. Namazy JA, Blais L, Andrews EB, Scheuerle AE, Cabana MD, Thorp JM, et al. Pregnancy outcomes in the omalizumab pregnancy registry and a disease-matched comparator cohort. J Allergy Clin Immunol. 2020 Feb 1;145(2):528-36.e1. 10. Breslow RG, Caiado J, Castells MC. Acetylsalicylic acid and montelukast block mast cell mediator-related symptoms during rapid desensitization. Ann Allergy Asthma Immunol. 2009;102(2):155-60.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"230-231"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39392468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anaphylactic Shock Following Cataract Surgery: A Documented Intracameral Cefuroxime Allergy.","authors":"C Mahiat, S Robaye, L Levecq, D Dumesnil, C Sohy","doi":"10.18176/jiaci.0741","DOIUrl":"https://doi.org/10.18176/jiaci.0741","url":null,"abstract":"","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"236-238"},"PeriodicalIF":7.2,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39392469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Reply to \"Spanish Society of Allergology and Clinical Immunology (SEAIC) Vision of Drug Provocation Tests\".","authors":"F Vega, C Blanco","doi":"10.18176/jiaci.0787","DOIUrl":"https://doi.org/10.18176/jiaci.0787","url":null,"abstract":"To the Editor: We read with interest the guideline on drug provocation tests (DPTs) by Audicana et al [1] on behalf of the Drug Allergy Committee of the Spanish Society of Allergology and Clinical Immunology that was published in the Journal of Investigational Allergology and the Clinical Immunology (JIACI) in October 2021. However, we are surprised that DPTs with iodinated contrast media (ICM) are now discouraged. This statement contradicts a previous proposal of the same Committee, which recommended DPTs with ICM when studying hypersensitivity reactions to these drugs. This advice was included in the \"Practical Guide for the Diagnosis and Management of Hypersensitivity Reactions to Contrast Media\" published in JIACI in 2016 [2]. In the new guideline, the contraindication to DPTs with ICM is based on potential toxicity. However, in our opinion, this is not a compelling reason. In fact, the same authors consider that DPTs with potentially more toxic drugs, such as nonsteroidal anti-inflammatory drugs, biologics, and cytostatic drugs, are indicated. Kidney damage is the most frequent toxicity reaction produced by ICM. However, the existence of contrast-induced nephropathy is currently questioned [3] and, in any case, is avoidable using a nephroprotective protocol adjusted to a renal risk score [4,5]. In other words, while many drugs are potentially toxic, the toxicity of ICM can be prevented using nephroprotective measures, especially if the patient is properly hydrated. In recent years, the lack of efficacy of premedication in preventing hypersensitivity reactions to ICM [6] has led to allergy studies including DPTs. These studies were performed by influential research groups, several of which were Spanish, with successful results [7-9]. Moreover, DPTs with ICM were also recommended by the EAACI in a recent position paper [10]. Therefore, we think that DPTs with ICM are a safe and necessary tool, both for establishing a diagnosis of drug allergy (in the case of inconclusive results with ICM in skin tests) and for confirming tolerance to an alternative ICM with previous negative skin test results. Perhaps the greatest difficulty in generalizing the use of DPTs with ICM is the lack of standardized protocols. Therefore, further studies are necessary to search for the most appropriate methodology. In conclusion, in the study of hypersensitivity reactions to ICM, we believe that DPTs should be the gold standard, as in any other drug allergy study.","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"241-242"},"PeriodicalIF":7.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40058700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to Take a Good Clinical History in Cases of Allergic Reactions to Medications.","authors":"C García-Avilés,&nbsp;J Martín-Lázaro,&nbsp;G Gastaminza","doi":"10.18176/jiaci.0819","DOIUrl":"https://doi.org/10.18176/jiaci.0819","url":null,"abstract":"<p><p>The clinical history is the cornerstone of the doctor´s work. When assessing patients consulting for a suspected hypersensitivity reaction to a drug, the details collected in the patient´s clinical history are essential when deciding which tests to perform and for making recommendations about which drugs the patient should avoid and which can be taken. This area is especially important today, since many patients are labeled as allergic to drugs, especially penicillins, without this being the case. This article reviews the importance of the clinical history in a patient with a hypersensitivity reaction to a drug and considers which data should be collected. Likewise, a record-based model is proposed to help standardize the clinical history.</p>","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"181-190"},"PeriodicalIF":7.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40058699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spanish Society of Allergology and Clinical Immunology (SEAIC) Vision of Drug Provocation Tests: Reply.","authors":"M T Audicana,&nbsp;N R Ortega","doi":"10.18176/jiaci.0808","DOIUrl":"https://doi.org/10.18176/jiaci.0808","url":null,"abstract":"Hospital Universitario de la Princesa Diego de León, 62 28006 Madrid, Spain E-mail: fvega13@hotmail.com 7. Vega F, Múgica MV, Bazire R, Argíz L, Belver MT, Friera A, et al. Adverse reactions to iodinated contrast media: Safety of a study protocol that includes fast full-dose parenteral challenge tests searching for an alternative contrast media. Clin Exp Allergy. 2020;50:271-4. 8. Doña I, Bogas G, Salas M, Testera A, Moreno E, Laguna JJ, et al. Hypersensitivity reactions to multiple iodinated contrast media. Front Pharmacol. 2020;11:575437. 9. Prieto-Garcia A, Tomas M, Pineda R, Tornero P, Herrero T, Fuentes V, et al. Skin test-positive immediate hypersensitivity reaction to iodinated contrast media: the role of controlled challenge testing. J Investig Allergol Clin Immunol. 2013;23:183-9. 10. Torres MJ, Trautmann A, Böhm I, Scherer K, Barbaud A, Bavbek S, et al. Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity. Allergy. 2021;76:1325-39. Spanish Society of Allergology and Clinical Immunology (SEAIC) Vision of Drug Provocation Tests: Reply","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"242-243"},"PeriodicalIF":7.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40058701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patch Testing as a Diagnostic Method for DRESS Syndrome That Brings Us Closer to a Certain Result: Letter to the Editor.","authors":"M I Danjuma,&nbsp;M Khatib","doi":"10.18176/jiaci.0794","DOIUrl":"https://doi.org/10.18176/jiaci.0794","url":null,"abstract":"1. Vega F, Blanco C. A reply to “Spanish Society of Allergology and Clinical Immunology (SEAIC) vision of drug provocation tests”. J Investig Allergol Clin Immunol. 2022;32:241-2. 2. Morcos SK, Thomsen HS, Exley CM. Contrast media: interactions with other drugs and clinical tests. Eur Radiol. 2005;15:1463-8. 3. Currie GM. Pharmacology, Part 5: CT and MRI Contrast Media. J Nucl Med Technol. 2019;47:189-202. doi: 10.2967/ jnmt.118.220012 4. Cha MJ, Kang DY, Lee W, Yoon SH, Choi YH, Byun JS, et al. Hypersensitivity Reactions to Iodinated Contrast Media: A Multicenter Study of 196 081 Patients. Radiology. 2019;293:117-24. https://doi.org/10.1148/ radiol.2019190485 5. Rosado Ingelmo A, Doña Diaz I, Cabañas Moreno R, Moya Quesada MC, García-Avilés C, García Nuñez I, et al. Clinical practice guidelines for diagnosis 49 and management of hypersensitivity reactions to contrast media. J Investig Allergol Clin Immunol. 2016;26:144-55. 6. Prieto-Garcia A, Tomas M, Pineda R, Tornero P, Herrero T, Fuentes V, et al. 71 Skin test-positive immediate hypersensitivity reaction to iodinated contrast 72 media: the role of controlled challenge testing. J Investig Allergol Clin Immunol. 2013;23:183-9. Patch Testing as a Diagnostic Method for DRESS Syndrome That Brings Us Closer to a Certain Result: Letter to the Editor","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"243-244"},"PeriodicalIF":7.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40058702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct Costs of Acute Rhinosinusitis in Spain: A Prospective and Observational Study (PROSINUS).","authors":"F Jaume,&nbsp;I Alobid,&nbsp;J Mullol,&nbsp;L Quintó","doi":"10.18176/jiaci.0525","DOIUrl":"https://doi.org/10.18176/jiaci.0525","url":null,"abstract":"<p><strong>Background and objectives: </strong>The incidence of acute rhinosinusitis (ARS) is high throughout the world. Although diagnosis is clinical and disease course is mostly self-limiting, diagnostic tools and medications are overused by physicians, thus increasing the direct medical costs of the disease. Objective: The aim of the PROSINUS study was to quantify the direct medical costs of management of ARS in Spain.</p><p><strong>Methods: </strong>We performed a prospective observational study of 1610 patients with a clinical diagnosis of nonbacterial, uncomplicated ARS. According to the duration of symptoms by the European Position Paper on Rhinosinusitis and Nasal Polyps, patients were classified as having viral or postviral ARS with different levels of severity. Direct medical costs were calculated based on medical visits, use of diagnostic tools, and medications prescribed.</p><p><strong>Results: </strong>Overall, the mean (SD) direct medical costs per episode were €322.3 (301.2) vs €441.1 (344.3) for viral and postviral ARS episodes, respectively (P<.001). When viral and postviral disease were compared, the medical costs per episode were €245.0 (265.4) vs €328.4 (301.9) for medical visits (P<.001), €38.1 (64.0) vs €61.9 (78.8) for diagnostic tools (P<.001), and €39.2 (25.9) vs €50.8 (25.3) for medications prescribed (P<.001).</p><p><strong>Conclusion: </strong>The direct medical costs of postviral ARS episodes were higher than those of viral episodes (common cold). Uncomplicated nonbacterial ARS represents an important socioeconomic burden owing to the excessive number of medical visits, use of diagnostic tools, and medications prescribed.</p>","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"481-488"},"PeriodicalIF":7.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.18176/jiaci.0525","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38177325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Case of Symmetric Drug-Related Intertriginous and Flexural Exanthema Induced by Meropenem.","authors":"D Blanco Garcia-Granero,&nbsp;R Barranco,&nbsp;I García-Moguel,&nbsp;V Velasco,&nbsp;M C Diéguez Pastor","doi":"10.18176/jiaci.0685","DOIUrl":"https://doi.org/10.18176/jiaci.0685","url":null,"abstract":"No residual lesions were observed. She subsequently tolerated linezolid. Skin biopsy of a macular lesion revealed superficial perivascular dermatitis of unspecific characteristics with a lymphocytic perivascular infiltrate limited to the epidermis. Eight weeks later, despite strict recommendations to avoid β-lactams, the patient took amoxicillin-clavulanic acid for a week with no adverse reactions. A detailed medical history compiled in the allergy department did not show any latex allergy or atopic disease. Written informed consent was obtained, and patch tests were performed with penicillin (10%), meropenem, ertapenem, and imipenem (5%). Readings at 48 and 96 hours yielded negative results. Skin prick tests (SPTs) and intradermal tests (IDTs) with immediate and delayed readings with benzylpenicilloyl octa-L-lysine, benzylpenilloate, penicillin, imipenem, and ertapenem yielded negative results. SPT with meropenem (100 mg/mL) was negative, whereas IDT with meropenem (1 mg/mL) became positive at 48 hours (Figure). All skin tests were performed on an area of previously inflamed skin. Given that the patient met the 5 clinical criteria [2] and had positive skin test results to meropenem, she was diagnosed with meropenem-induced SDRIFE, and carbapenems were forbidden. The positive result in the delayed IDT reading and the histopathological findings point to a type 4 hypersensitivity mechanism, as reported elsewhere [4,5]. First Case of Symmetric Drug-Related Intertriginous and Flexural Exanthema Induced by Meropenem","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"516-517"},"PeriodicalIF":7.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25428920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Where Has All the Nasal Polyposis Gone?","authors":"L Ortega-Martin,&nbsp;D Betancor,&nbsp;B Barroso,&nbsp;M Valverde-Monge,&nbsp;J Santillan,&nbsp;J M Villacampa,&nbsp;J Sastre","doi":"10.18176/jiaci.0679","DOIUrl":"https://doi.org/10.18176/jiaci.0679","url":null,"abstract":"","PeriodicalId":520676,"journal":{"name":"Journal of investigational allergology & clinical immunology","volume":" ","pages":"500-502"},"PeriodicalIF":7.2,"publicationDate":"2021-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25362622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}