Angewandte Chemie (International ed. in English)最新文献_第2页

Titanium-Catalyzed Synthesis of Multisubstituted Glutarimides Bearing Quaternary Carbon Centers-Scope, Mechanism, and Bioactivity Studies. 钛催化合成含季碳中心的多取代戊二酰亚胺——范围、机理和生物活性研究。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-08-28 DOI: 10.1002/anie.6119479

Wendi Yang, Ximei Tian, Shuhui Tong, Min Jiang, Wei Zhang, Lipeng Wu

引用次数: 0

Coordination-Triggered Disassembly of Robust Two-Dimensional Fullerene Frameworks via Intercage C─C σ-Bond Scission. 通过Intercage C─C σ-键断裂协调触发二维强健富勒烯骨架的拆卸。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-08-26 DOI: 10.1002/anie.1816694

Shuwen Jia, Feiyang Huang, Xin Yuan, Zhicong Hu, Yusheng Lu, Jinwei Zhang, Chenli Huang, Kun Guo, Tao Yang, Xing Lu, Lipiao Bao

{"title":"Coordination-Triggered Disassembly of Robust Two-Dimensional Fullerene Frameworks via Intercage C─C σ-Bond Scission.","authors":"Shuwen Jia, Feiyang Huang, Xin Yuan, Zhicong Hu, Yusheng Lu, Jinwei Zhang, Chenli Huang, Kun Guo, Tao Yang, Xing Lu, Lipiao Bao","doi":"10.1002/anie.1816694","DOIUrl":"10.1002/anie.1816694","url":null,"abstract":"Two-dimensional fullerene frameworks such as Mg4C60 and its metal-free derivative 2D-C60 are densely cross-linked all-carbon lattices, in which each C60 cage is tethered to six neighbors through eight intercage C─C σ-bonds. Formed under high-temperature conditions (ca. 500°C-600°C), these junction-rich architectures are generally resistant to post-synthetic lattice editing or recovery of intact fullerene building blocks. However, we show here that mild transition-metal coordination can unlock these frameworks under mild solution conditions by cleaving covalent intercage C─C bonds. Treating Mg4C60 with W(CO)4(Ph2PCH2)2 leads to measurable depolymerization and time-dependent formation of molecular C60. NiCl2(PMe3)2 promotes substantially more efficient cleavage and enables direct detection of a cleavage intermediate (m/z = 899), supporting coordination-linked bond-scission pathway. Density functional theory shows that C60-M-C60 bridge formation increases the exothermicity for intercage C─C bond scission, and rationalizes the stronger thermodynamic driving force for Ni-catalytic system relative to W-catalytic system. Furthermore, Mg2+ removal markedly suppresses depolymerization, indicating that Mg intercalation promotes junction opening through MgCl2 formation and charge-state modulation. These results establish coordination-triggered intercage bond cleavage as a strategy for lattice editing and programmable disassembly in carbon-rich 2D frameworks.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e1816694"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Self-Amplifying AIE Probe for HClO-Activatable Imaging and Antioxidative/Anti-Inflammatory Therapy of Thoracic Aortic Dissection. 自扩增AIE探针用于hcl活化显像及抗氧化/抗炎治疗胸主动脉夹层。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-09-02 DOI: 10.1002/anie.3622603

Yanzi Xu, Yunpeng Luo, Jiale Shen, Zihao Deng, Anran Gao, Shengyi Yang, Jacky W Y Lam, Ryan T K Kwok, Changhuo Xu, Lingjie Meng, Weixun Duan, Dongfeng Dang, Ben Zhong Tang

{"title":"Self-Amplifying AIE Probe for HClO-Activatable Imaging and Antioxidative/Anti-Inflammatory Therapy of Thoracic Aortic Dissection.","authors":"Yanzi Xu, Yunpeng Luo, Jiale Shen, Zihao Deng, Anran Gao, Shengyi Yang, Jacky W Y Lam, Ryan T K Kwok, Changhuo Xu, Lingjie Meng, Weixun Duan, Dongfeng Dang, Ben Zhong Tang","doi":"10.1002/anie.3622603","DOIUrl":"10.1002/anie.3622603","url":null,"abstract":"Thoracic aortic dissection (TAD) is a highly lethal cardiovascular disease, yet its accurate diagnosis and effective treatment remain challenging due to poor imaging contrast and insufficient specificity. Leveraging the overexpressed reactive oxygen species (ROS) in TAD, we reported a hypochlorous acid (HClO)-activatable molecular probe DT-PZ. It enables two-stage self-amplifying fluorescence imaging (chemical activation and then physical aggregation) and light-independent therapy on a single chemical entity. The probe initially exhibits quenched fluorescence via photoinduced electron transfer (PET). Two pathways can turn on the fluorescence via chemical activation: (1) oxidation by HClO blocks PET and turns on the emission; (2) photo-triggered radicals generation of HClO (via chloride ions or myeloperoxidase) to activate neighboring probes, creating self-amplifying fluorescence. Upon accumulation at the lesion site, the physical aggregation caused by the aggregation-induced emission effect further amplifies the fluorescence signals. This two-stage fluorescence amplification mechanism enables TAD visualization within 2 min in vivo. For therapy, the phenothiazine scavenges excess ROS during non-illuminated periods, down-regulates the NF-κB/P65 signal pathway, and up-regulates eNOS and P-Akt expressions, protecting endothelial homeostasis and then improving murine survival from 50% to 90%. Collectively, DT-PZ synergizes self-amplifying fluorescence imaging with light-independent antioxidation/anti-inflammatory therapy, holding great promise for managing deep-seated cardiovascular diseases.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e3622603"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proton Capture and Relay Codesign Enables a pH-Neutral All-Organic Aqueous Proton Battery. 质子捕获和继电器协同设计实现ph中性全有机水质子电池。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-09-02 DOI: 10.1002/anie.8800816

Jiyao Zhou, Jiapeng Zhao, Xinyue Deng, Xiaojing Sun, Hao Guo, Chenghui Sun, Weixiao Ji, Siping Pang, He Huang

{"title":"Proton Capture and Relay Codesign Enables a pH-Neutral All-Organic Aqueous Proton Battery.","authors":"Jiyao Zhou, Jiapeng Zhao, Xinyue Deng, Xiaojing Sun, Hao Guo, Chenghui Sun, Weixiao Ji, Siping Pang, He Huang","doi":"10.1002/anie.8800816","DOIUrl":"10.1002/anie.8800816","url":null,"abstract":"Aqueous all-organic proton batteries promise safe, sustainable, and high-rate energy storage, but operation under near-neutral conditions is hindered by low proton activity and competition from nonproton charge carriers. Here, we report a proton capture and relay codesign strategy that enables proton-dominated charge storage without strongly acidic electrolytes. The electrode pair comprises two N-centered redox molecules with high proton affinity: an air-stable preprotonated imine cathode, DCTA-2H, and a low-potential azo anode, BCC. The electrolyte is concentrated NH4OAc, a near-neutral proton-transfer medium in which NH4 + forms hydrogen-bonded contacts with imine/azo sites and facilitates interfacial proton transfer rather than being stored predominantly as an intact ion. The resulting BCC||DCTA-2H full cell delivers a discharge voltage of ≈0.85 V and a capacity of 270.9 mAh gBCC -1, retains 86.5% of its capacity after 3,000 cycles, and remains operable at -50°C. This work establishes coupled electrode-electrolyte design as a route to near-neutral all-organic aqueous proton batteries.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e8800816"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A microRNA-21-Activatable Two-Stage Signal Amplification Probe for Catalytic Photodynamic Therapy. 用于催化光动力治疗的microrna -21可激活两级信号放大探针。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-09-04 DOI: 10.1002/anie.6552551

Yikun Li, Fuping Han, Yingjie Sun, Xin Li, Saran Long, Wen Sun, Jianjun Du, Chong Peng, Jiangli Fan, Xiaojun Peng

{"title":"A microRNA-21-Activatable Two-Stage Signal Amplification Probe for Catalytic Photodynamic Therapy.","authors":"Yikun Li, Fuping Han, Yingjie Sun, Xin Li, Saran Long, Wen Sun, Jianjun Du, Chong Peng, Jiangli Fan, Xiaojun Peng","doi":"10.1002/anie.6552551","DOIUrl":"10.1002/anie.6552551","url":null,"abstract":"Photodynamic therapy (PDT) is noninvasive but lacks tumor specificity, while microRNAs (miRNAs) are highly specific biomarkers yet too low in abundance (pM-nM) to directly trigger therapy. Here we report ECyTz, a microRNA-21(miR-21)-activatable theranostic probe that achieves two-stage signal amplification. In the first stage, one miR-21 molecule catalytically activates multiple ECyTz probes through tetrazine-mediated transfer (TMT) bioorthogonal chemistry (turnover number 5.6-41 at 10-100 nM), because the probe releases the active photosensitizer upon reaction while the intact miRNA remains to trigger further cycles. In the second stage, each activated photosensitizer generates abundant reactive oxygen species (ROS). ECyTz remains non-fluorescent and photodynamically inert until miR-21 triggers a proximity-dependent inverse electron-demand Diels-Alder reaction, restoring near-infrared (NIR) fluorescence (27-fold) and robust ROS generation. The probe exhibits strict sequence specificity, minimal dark toxicity, and potent antitumor efficacy in xenograft models (86.7% tumor growth inhibition with no observable systemic toxicity), with upregulation of the downstream tumor suppressor PTEN confirming on-target activation. This modular miRNA-actuated platform with tunable recognition sequences establishes a proof-of-concept for catalytic bio-orthogonal signal amplification, offering a programmable strategy for precision tumor-selective photodynamic therapy.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e6552551"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148893286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Operando X-ray Spectroscopy Unveils Light-Driven Redox Selectivity for Photo-Assisted Li-S Batteries. Operando x射线光谱学揭示光辅助锂电池的光驱动氧化还原选择性。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-09-04 DOI: 10.1002/anie.1445925

Meng Cai, Pengpeng Zhang, Yukun Li, Yixin Wei, Kaizhen Li, Ruiliu Yang, Yiliang Chen, Guosheng Shao, Peng Zhang

{"title":"Operando X-ray Spectroscopy Unveils Light-Driven Redox Selectivity for Photo-Assisted Li-S Batteries.","authors":"Meng Cai, Pengpeng Zhang, Yukun Li, Yixin Wei, Kaizhen Li, Ruiliu Yang, Yiliang Chen, Guosheng Shao, Peng Zhang","doi":"10.1002/anie.1445925","DOIUrl":"10.1002/anie.1445925","url":null,"abstract":"Photo-assisted lithium-sulfur batteries (PALSBs) can accelerate the sluggish redox kinetics of sulfur cathodes. However, the introduced light field inevitably complicates interfacial reactions, necessitating in situ evidence under realistic operating conditions. Here, we construct a TiO2/FePS3 (TF) p-n junction bifunctional photoelectrode and employ a multiphysics-coupled in situ x-ray spectroscopic technique to elucidate light-regulated catalysis from the interface into the bulk. Operando low-energy XPS identifies potential interfacial catalytic sites. High-energy operando XAFS is, for the first time, applied in PALSBs to track the K-edge position of catalytic centers throughout cycling. The results show that the reversible dynamic valence evolution synchronizes with the stepwise sulfur redox process, revealing that photogenerated carriers and electrocatalytic electrons act cooperatively to promote polysulfide conversion. DFT calculations corroborate, from thermodynamic and kinetic perspectives, that illumination strengthens polysulfide anchoring and lowers the energy barriers of key conversion steps, consistent with the operando spectroscopic observations. Benefiting from this photoelectrochemical co-regulation, the TF-based PALSB maintains excellent reversible capacity and cycling stability under high sulfur loading and low electrolyte content. This work establishes a characterization paradigm for the rational design of high-performance photo-assisted Li-S cathodes.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e1445925"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148893298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnesium-Retention Assisted Synthesis of High-Performance Zintl Thermoelectrics. 镁保留辅助合成高性能锌热电材料。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-08-28 DOI: 10.1002/anie.9935383

Boxuan Hu, Xiao-Lei Shi, Tianyi Cao, Nanhai Li, Chao Zhang, Sen Wang, Siqi Liu, Meng Li, Dmitri Golberg, Zhi-Gang Chen

{"title":"Magnesium-Retention Assisted Synthesis of High-Performance Zintl Thermoelectrics.","authors":"Boxuan Hu, Xiao-Lei Shi, Tianyi Cao, Nanhai Li, Chao Zhang, Sen Wang, Siqi Liu, Meng Li, Dmitri Golberg, Zhi-Gang Chen","doi":"10.1002/anie.9935383","DOIUrl":"10.1002/anie.9935383","url":null,"abstract":"For decades, performance optimization of Mg3(Bi, Sb)2-based thermoelectric materials has mainly relied on doping and alloying strategies, while the influence of synthesis-process innovation on thermoelectric mechanisms and properties has remained largely unexplored. Here, we develop a magnesium-retention assisted synthesis (MRAS) strategy that stabilizes Mg through a sacrificial Mg reservoir and an inert-gas-regulated melting environment, effectively suppressing Mg volatilization and chemical instability during high-temperature synthesis. MRAS enables scalable fabrication of phase-pure, compositionally uniform Mg-based alloys without costly tantalum encapsulation. The resulting Mg-rich Mg3.15Bi1.5Sb0.49Te0.01 features interconnected Mg-rich regions and multiscale defects that synergistically promote electrical transport and suppress lattice thermal conductivity, delivering an ultrahigh power factor of 41.7 µW cm-1 K-2, a ZT of 1.2 ± 0.1 at 323 K, and a peak ZT of 1.8 ± 0.1 at 523 K. MRAS is also compatible with conventional compositional engineering: Ba doping at the Mg site further reduces thermal conductivity through point-defect scattering while largely preserving the power factor, yielding a ZT around 1.9 ± 0.1 at 523 K in Mg3.144Ba0.006Bi1.5Sb0.49Te0.01. Moreover, successful extension to MgCu2 and MgAgSb highlights the broad applicability of MRAS as a scalable synthesis platform for high-performance Mg-based materials.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e9935383"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13676423/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elucidating Photo-Kinetic Control in Photothermal Reverse Water-Gas Shift Reaction. 光热逆水气转换反应的光动力学控制研究。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-09-01 DOI: 10.1002/anie.4338333

Junchuan Sun, Rui Song, Chang Xu, Xue Ding, Wanguo Gao, Athanasios A Tountas, Zhe Lu, Jiakun Wang, Zeshu Zhang, Xiaolu Zhuo, Yingfang Yao, Zhigang Zou, Geoffrey A Ozin, Lu Wang

{"title":"Elucidating Photo-Kinetic Control in Photothermal Reverse Water-Gas Shift Reaction.","authors":"Junchuan Sun, Rui Song, Chang Xu, Xue Ding, Wanguo Gao, Athanasios A Tountas, Zhe Lu, Jiakun Wang, Zeshu Zhang, Xiaolu Zhuo, Yingfang Yao, Zhigang Zou, Geoffrey A Ozin, Lu Wang","doi":"10.1002/anie.4338333","DOIUrl":"10.1002/anie.4338333","url":null,"abstract":"Unlike the well-known charge-carrier kinetics in traditional photocatalysis, a knowledge gap remains regarding the photo-kinetic effects in heterogeneous photothermal catalysis. Conventionally, light is mainly regarded as a source of charge carriers and localized heating, yet how these light-induced effects alter intrinsic reaction kinetics, particularly the rate-determining step (RDS), remains unclear. Here, we provide direct kinetic evidence that illumination tunes the RDS in an archetypal Mars-van Krevelen (MvK) reverse water-gas shift (RWGS) reaction over In-doped MoO2. Under illumination, photogenerated electrons enrich In sites, promoting H2 activation and spillover while accelerating H2O desorption, thereby shifting the RDS from the H2-reduction half-reaction to the CO2-oxidation half-reaction. This kinetic modulation significantly enhances catalytic performance and lowers the apparent activation energy. Overall, this work elucidates the kinetic role of light in photothermal CO2 conversion, offering new insights into optimizing solar-driven catalytic processes.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e4338333"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13676417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148868369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Engineering-Editable Hybrid Membrane‑Camouflaged DNA Origami Drug Enables Checkpoint Blockade and Immune Activation for Triple-Negative Breast Cancer Immunotherapy. 一种工程可编辑的混合膜伪装DNA折纸药物可用于三阴性乳腺癌免疫治疗的检查点阻断和免疫激活。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-08-29 DOI: 10.1002/anie.7162372

Xiaqing Gong, Han Yuan, Ying Fang, Mingming Song

{"title":"An Engineering-Editable Hybrid Membrane‑Camouflaged DNA Origami Drug Enables Checkpoint Blockade and Immune Activation for Triple-Negative Breast Cancer Immunotherapy.","authors":"Xiaqing Gong, Han Yuan, Ying Fang, Mingming Song","doi":"10.1002/anie.7162372","DOIUrl":"10.1002/anie.7162372","url":null,"abstract":"The clinical response to immunotherapy in triple-negative breast cancer (TNBC) is often limited by the immunosuppressive microenvironment, immune cell exhaustion, and multidrug resistance. Through a high-throughput screen of 2,500 FDA-approved drugs using a three-dimensional tumor organoid platform, we identified thonzonium bromide (THO) as an inducer of gasdermin D (GSDMD)-mediated pyroptosis, which results in the release of damage-associated molecular patterns (DAMPs) to activate antitumor immunity. To achieve targeted delivery, we designed a core-shell-structured biomimetic nanoparticle (THO/AMT-si NP) consisting of a core formed by tetrahedral DNA (TDN NPs) constructed using DNA origami technology, which is loaded with THO and P-gp siRNA, and an outer layer coated with a programmatically designed hybrid membrane (AREP). These findings indicate that THO/AMT-Si NPs can effectively target TNBC tumors, convert \"cold\" tumors into \"hot\" tumors by inducing pyroptosis in cancer cells, reverse immune cell exhaustion, and simultaneously overcome cancer cell multidrug resistance, thereby achieving synergistic inhibition of tumor growth and metastasis. In summary, this biomimetic nanomedicine enhances immunotherapy for TNBC by combining synergistic cascade targeting, immune checkpoint blockade, and thermosis-mediated immune activation.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e7162372"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visible Light-Mediated Photoclick and Thermally Reversible Furanic Dithioacetal Chemistry for Circular 3D Printing. 可见光介导的光点击和热可逆的呋喃二硫缩醛化学循环3D打印。

IF 16.9

Angewandte Chemie (International ed. in English) Pub Date : 2026-10-19 Epub Date: 2026-08-28 DOI: 10.1002/anie.3093462

Tiantian Ni, Bo Yang, Jingjun Wu, Xiaoli Jiang, Ben He, Hao Xing, Luping Lu, Liwei Chen, Zhibo Li, Tao Xie, Ning Zheng

{"title":"Visible Light-Mediated Photoclick and Thermally Reversible Furanic Dithioacetal Chemistry for Circular 3D Printing.","authors":"Tiantian Ni, Bo Yang, Jingjun Wu, Xiaoli Jiang, Ben He, Hao Xing, Luping Lu, Liwei Chen, Zhibo Li, Tao Xie, Ning Zheng","doi":"10.1002/anie.3093462","DOIUrl":"10.1002/anie.3093462","url":null,"abstract":"Photoclick chemistry has become essential for photocurable 3D printing due to its rapid, selective, and spatiotemporally controlled bond formation. Advancing toward circular manufacturing, however, requires photoclick systems that also enable thermally reversible bond cleavage for material recycling. To meet this requirement, we report a furanic dithioacetal-based photoclick platform that integrates visible-light-induced polymerization with intrinsic thermal reversibility. The monomers, derived from bio-based furanic aldehydes and thiols, are solvent-free liquids, ensuring homogeneous formulations well-suited for 3D printing. To address the spectral mismatch of conventional photocatalysts, a thioxanthone-based photoacid system is investigated, enabling efficient bond formation under visible light compatible with commercial digital light processing (DLP) printing. The resulting polymer networks exhibit tunable crosslinking densities, allowing precise control over mechanical properties. Crucially, the dynamic furanic dithioacetal linkages enable depolymerization of the printed materials into re-printable oligomers, with no loss of performance over multiple recycling cycles. This work establishes a chemically integrated strategy that unifies visible-light processability, solvent-free formulation, bio-based origin, and closed-loop recyclability, thus establishing a robust foundation for circular photopolymer platforms.","PeriodicalId":520556,"journal":{"name":"Angewandte Chemie (International ed. in English)","volume":" ","pages":"e3093462"},"PeriodicalIF":16.9,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148852288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0