{"title":"Seizure Provocation Following Low-Energy Burst Dorsal Root Spinal Cord Stimulator Implant in Patient with Chronic Back Pain and Pre-Existing Seizures: Case Report.","authors":"Josephine Nwankwo, Angela Nwankwo, Renato Martin, Ovie Enaohwo, Yacoub Khatab, Emanuel Narcis Husu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Spinal cord stimulation (SCS) is an established treatment of chronic pain refractory to conservative management. While it is thought to work through neuromodulation of spinal cord pathways, its impact on central nervous system excitability is not well understood. There are afew reports highlighting seizures temporally associated with SCS.</p><p><strong>Case report: </strong>This case involves a 78-year-old man with chronic low back pain secondary to lumbar facet arthropathy and a history of seizure disorder. He underwent spinal cord stimulator implantation after failing conservative management for back pain. The implant provided significant pain relief and functional improvement. However, within 9 months of implantation, he developed recurrent seizures. Seizure activity ceased after removal of the SCS, but unfortunately, his pain returned.</p><p><strong>Conclusions: </strong>This case highlights the unusual and poorly understood complication of SCS-induced seizures, emphasizing the need for caution when considering neuromodulation therapy in patients with a known seizure history.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"535-537"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left Parasagittal Solitary Fibrous Tumor Presenting With Lumbar Radiculopathy-Like Symptoms: A Case Report.","authors":"Thomas Hoang Ngo, Andrew Garcia, Peter Minh Huynh","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Lumbar radiculopathy is typically attributed to degenerative spinal disease, but central lesions can rarely mimic its sensory and motor features. Parasagittal tumors involving the motor and sensory leg regions may present with contralateral weakness, paresthesia, or pain that can be mistaken for peripheral pathology.</p><p><strong>Case report: </strong>A 60-year-old man with chronic postoperative lumbar symptoms developed progressive bilateral leg weakness, worsening pain, and new right arm shaking. Lumbar imaging showed no clear correlate, but brain magnetic resonance imaging revealed a large left parasagittal solitary fibrous tumor compressing the leg motor-sensory cortices. Following craniotomy and adjuvant radiation, he experienced marked improvement in strength, sensation, and functional mobility, supporting a cortical source for symptoms previously attributed to radiculopathy.</p><p><strong>Conclusions: </strong>Persistent radicular-like symptoms unresponsive to spinal intervention should prompt evaluation for central causes, especially when new upper motor neuron signs or multifocal deficits emerge.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"481-484"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-Term Tapentadol Use for Neuropathic Pain in a Hemodialysis Patient with End-stage Renal Disease: A Case Report.","authors":"Mattison Shepherd, Morgan Bruketta","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Tapentadol is generally not recommended in patients with end-stage renal disease on hemodialysis due to concerns about metabolite accumulation and limited safety data. Evidence in this population is scarce, with no major trials to date.</p><p><strong>Case report: </strong>A 58-year-old man with end-stage renal disease on hemodialysis developed ischemic monomelic neuropathy after fistula surgery. Previous opioids and tramadol were ineffective; pregabalin, gabapentin, and oxcarbazepine caused intolerable side effects. Due to ongoing citalopram therapy, serotonin-norepinephrine reuptake inhibitor changes were avoided. Tapentadol 75 mg three times daily was started and continued for 20 months, resulting in sustained pain control without observed adverse effects or clinical signs suggestive of drug accumulation; pharmacokinetic drug accumulation could not be assessed because blood and urine drug levels were unavailable.</p><p><strong>Conclusions: </strong>This case suggests long-term tapentadol may be a safe and effective pain management option in selected patients with end-stage renal disease on hemodialysis, though further study is needed.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"511-513"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interventional Management of Chronic Neuropathic Cervical Pain Following Nerve Sheath Tumor Resection and Radiation: A Case Report.","authors":"Kevin Tran, Evan Banks, Mahmood Gharib","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Chronic neuropathic pain after head and neck cancer is common and difficult to treat, especially when compounded by surgical and radiation-related neural injury. This case illustrates persistent superficial cervical plexopathy after tumor resection and adjuvant radiation with limited response to standard therapy.</p><p><strong>Case report: </strong>A man in his 30s developed constant, allodynic left anterolateral neck pain after resection of a carotid triangle nerve sheath sarcoma and postoperative radiation. Conservative measures (physical therapy, topical agents, gabapentin) provided minimal relief. An ultrasound-guided superficial cervical plexus block resulted in only transient pain relief, with symptoms recurring within hours. A trial of 2 cycles of botulinum toxin type A injections resulted in minimal and nonsustained improvement.</p><p><strong>Conclusion: </strong>Post-treatment cervical neuropathic pain can be refractory despite standard care. A multidisciplinary, individualized approach that integrates diagnostic blocks, targeted interventions, and cancer rehabilitation may improve function and quality of life in selected patients.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"507-510"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Trigger Point Injections for Symptomatic Treatment of Median and Ulnar Neuropathy: A Case Report.","authors":"Roi Medina, Marcos Henriquez, Max Fitzgerald","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Myofascial pain syndrome may coexist with other musculoskeletal conditions, including entrapment neuropathies. The relationship between myofascial dysfunction and entrapment neuropathy remains poorly understood, and the evaluation and management of patients presenting with overlapping symptomatology can be challenging.</p><p><strong>Case report: </strong>We report on the use of trigger point injections (TPIs) in a 49-year-old woman with median and ulnar entrapment neuropathies and concurrent myofascial pain. The patient underwent a series of 8 TPI sessions targeting muscles of the shoulder, arm, and hand, resulting in sustained improvement of both myofascial and neuropathic symptoms for up to 2 years. No complications were observed during the treatment course.</p><p><strong>Conclusions: </strong>This case highlights the potential role of TPIs as a therapeutic option for patients with entrapment neuropathies and concomitant myofascial pain. Further investigation is warranted to better understand the relationship between the 2 conditions and to evaluate the efficacy and durability of this treatment approach.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"497-500"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sidharth Sahni, Harrison Jordan, Anishinder Parkash, Ruben Dovlatyan, David Jevotovsky, Blanka Heary, Michael E Farrell Ii
{"title":"Dorsal Root Ganglion Stimulation for Chronic Postoperative Abdominal Pain: A Case Report.","authors":"Sidharth Sahni, Harrison Jordan, Anishinder Parkash, Ruben Dovlatyan, David Jevotovsky, Blanka Heary, Michael E Farrell Ii","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Chronic postoperative abdominal pain (CPAP) is a common condition that significantly affects patients' lives with increased gastrointestinal symptoms and decreased quality of life (QoL). Management of CPAP continues to be challenging, and adequate analgesia remains difficult to achieve.</p><p><strong>Case report: </strong>A 77-year-old woman with a history of multiple abdominal surgeries presented with chronic right-sided abdominal wall pain with possible causalgia. After failing multiple interventions, dorsal root ganglion stimulation (DRG-S) at the T8-T9 level provided significant relief.</p><p><strong>Conclusions: </strong>We present a case of a female patient with a history of multiple abdominal surgeries and CPAP, who experienced successful pain relief through DRG-S. Emerging research suggests that neuromodulations consisting of spinal cord stimulator (SCS) or DRG-S may be effective in managing visceral abdominal and pelvic pain caused by repeated distension and hyperalgesia, though more robust research studies are needed.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"515-519"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peripheral Nerve Stimulation of the Saphenous Nerve at the Adductor Canal for Chronic Post-Surgical Knee Pain Following Total Knee Arthroplasty.","authors":"Yacine Issioui, Loc Lam, Emanuel Narcis Husu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Total knee arthroplasty (TKA) is effective for osteoarthritis (OA), yet many patients develop chronic postoperative pain. Peripheral nerve stimulation (PNS) has emerged as a minimally invasive alternative for refractory pain.</p><p><strong>Case report: </strong>A 79-year-old man with right total knee arthroplasty (TKA) presented with right knee pain unresponsive to genicular nerve radiofrequency ablation. The pain, rated 8/10, was localized to the superomedial knee and worsened with ambulation. Before knee replacement, his pain was confined to the intra-articular space. A peripheral nerve stimulation (PNS) trial targeting the saphenous nerve at the adductor canal was performed under ultrasound guidance. The patient reported 100% pain relief at 1-month follow-up. A Permanent Nalu implant was subsequently placed and that 100% pain relief continued for more than 2 months.</p><p><strong>Conclusions: </strong>This case demonstrates the use of ultrasound-guided peripheral nerve stimulation targeting the saphenous nerve for chronic postsurgical knee pain following total knee arthroplasty. The intervention provided complete pain relief, underscoring peripheral nerve stimulation as a promising, minimally invasive option for chronic postoperative pain unresponsive to conventional treatments.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"485-489"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peripheral nerve stimulation for Sphenopalatine Ganglion and auriculotemporal nerve in refractory Posttraumatic Trigeminal Neuropathy.","authors":"Hesham Elsharkawy, Lucas Baldo, Faria Nisar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Chronic facial pain has varying causes and etiologies. Often, diagnosis and management require a combination of pharmacological and surgical interventions. Externally powered peripheral nerve stimulation (PNS) is an emerging treatment for refractory facial pain. This report describes a case of combined auriculotemporal nerve stimulation (ATNS) and sphenopalatine ganglion stimulation (SPGS) for a patient with complex facial pain.</p><p><strong>Case report: </strong>A 74-year-old man with a decade-long history of intractable facial pain, following traumatic injuries, underwent a temporary PNS trial of combined ATNS and SPGS using the Freedom® PNS System (Curonix). The trial resulted in significant pain reduction and sustained relief for over 18 months post-removal.</p><p><strong>Conclusions: </strong>Long-lasting relief following a short-term trial suggests that ATNS and SPGS neuromodulation may produce enduring benefits after device removal. These findings warrant further investigation into the mechanisms and broader application of PNS in treating complex facial pain.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"563-567"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan Kallini, Drew Barron, Sloan Nesbit, Bryan Ganter, Gregory Umphrey, Min Yoo
{"title":"Radiation-Induced Digital Neuropathy in an Interventional Physiatrist: Rapid and Durable Relief after Targeted Digital Nerve Block: Case Report.","authors":"Jonathan Kallini, Drew Barron, Sloan Nesbit, Bryan Ganter, Gregory Umphrey, Min Yoo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Hands are frequently closest to the primary beam during fluoroscopy and can sustain cumulative exposure. Case reports of focal digital neuropathy in proceduralists are rare; imaging may be nondiagnostic, and treatment pathways unclear.</p><p><strong>Case report: </strong>A 36-year-old interventional physiatrist developed 9 months of cyclical, severe allodynia localized to the radial half of the right index distal phalanx. Infectious/inflammatory treatments and hand therapy were ineffective. MRI was nonspecific; ultrasound showed focal hyperemia. Given typical hand positioning during procedures, radiation-induced digital neuropathy was suspected. A targeted radial digital nerve block at the distal interphalangeal level achieved near-complete pain relief by day 10 with durable benefit at 12 months.</p><p><strong>Conclusion: </strong>In clinicians with focal fingertip allodynia and nondiagnostic imaging, consider radiation-induced digital neuropathy. When conservative care fails, a targeted digital nerve block may provide rapid, durable relief and underscores best-practice radiation safety.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"553-557"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148877186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Subchondral Vertebral Body Bone Marrow-Derived Mesenchymal Stem Cells Injections Combined With Lumbar Disc Arthroplasty for Vertebrogenic and Discogenic Pain: A Novel Case Report.","authors":"Sudhir Diwan, Maanas Chiplunkar, Shelby D Munoz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Chronic axial low back pain is often multifactorial, involving overlapping facetogenic, discogenic and vertebrogenic pain generators. Although several treatment modalities exist for clear-cut cases in which the primary pain generator is well defined, optimal management for patients with mixed pathology remains unclear.</p><p><strong>Case report: </strong>In this case, a 27-year-old man presented with refractory axial low back pain and severely limited range of motion associated with Modic type 1 endplate changes and discogenic pain at L3-4 and L5-S1 confirmed by provocative discography. After transient benefit from basivertebral nerve ablation and minimal response to medial branch blocks, the patient underwent a multimodal treatment intervention, consisting of subchondral vertebral endplate bone marrow aspirate concentrate (BMAC) injections at L3-4, intradiscal BMAC injection at L5-S1, and lumbar disc arthroplasty at L3-4. Pain improved from 6/10 in severity pre-intervention to 1-2/10 in severity, with a 75% increase in lumbar range of motion at 4 months post-intervention.</p><p><strong>Conclusions: </strong>This case presents an innovative, motion-preserving restorative treatment approach for multifactorial axial low back pain, combining targeted BMAC injections to the subchondral vertebral endplates and intervertebral disc with disc arthroplasty.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"10 6","pages":"545-551"},"PeriodicalIF":0.0,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}