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Nanotechnology Pain Patch Relieves Chronic Back Pain: A Case Report. 纳米疼痛贴片缓解慢性背痛：一例报告。
Pain medicine case reports Pub Date : 2025-04-01
Danielle Levin, Sarah Levin, Abhin Shah, Martin Acquadro
{"title":"Nanotechnology Pain Patch Relieves Chronic Back Pain: A Case Report.","authors":"Danielle Levin, Sarah Levin, Abhin Shah, Martin Acquadro","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Low back pain is a debilitating symptom that may develop into a refractory chronic condition, resistant to physical, medical, psychological, and/or interventional therapy options. We would like to share the first report of a nanotechnology pain patch providing > 90% chronic back pain relief for 3 months.</p><p><strong>Case report: </strong>A 75-year-old man with chronic low back pain secondary to L2-L3 disc herniation suffered from pain for > 35 years. He found physical therapy, baclofen, low-dose opioids, and lumbar epidural steroid injection ineffective. A trial of a nanotechnology pain patch (nCAP Signal Relief Patch) worn daily provided the patient with consistent 90% to 100% back pain relief and enabled the patient to have significant functional improvement.</p><p><strong>Conclusions: </strong>This case report demonstrates that the nCAP Signal Relief Patch could be a simple, safe, noninvasive, and effective treatment option for those affected by chronic low back pain.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"115-118"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bridging Antiplatelet Therapy With Cangrelor in Spinal Cord Stimulator Trial and Implant for Patient With Refractory Angina: A Case Report. 在脊髓刺激器试验和植入治疗难治性心绞痛患者中使用康格乐进行桥接抗血小板治疗1例。
Pain medicine case reports Pub Date : 2025-04-01
Marshall Yuan, Angie Kuang, David Hao
{"title":"Bridging Antiplatelet Therapy With Cangrelor in Spinal Cord Stimulator Trial and Implant for Patient With Refractory Angina: A Case Report.","authors":"Marshall Yuan, Angie Kuang, David Hao","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Antiplatelet medications increase the risk of neuraxial bleeding during spinal cord stimulator (SCS) trials and implants, necessitating adequate discontinuation. However, interrupting antiplatelet therapy is undesirable in patients at high risk for thromboembolism. Cangrelor, a novel nonthienopyridine adenosine triphosphate analog, has a rapid onset and offset that can be used to bridge antiplatelet therapy prior to procedures involving neuraxial access, minimizing the risk of subtherapeutic anticoagulation.</p><p><strong>Case report: </strong>We present the case of a 44-year-old man with an extensive cardiac history who underwent neuromodulation for refractory angina. The patient was transitioned from prasugrel to cangrelor, with cangrelor being discontinued 3 hours prior to the tunneled SCS trial and subsequent implant. He showed no signs of any complications, including neurological issues, related to bleeding.</p><p><strong>Conclusions: </strong>This case illustrates the successful use of cangrelor as an antiplatelet bridge prior to a neuraxial procedure.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"147-150"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Peripheral Nerve Stimulation for Acute Vertebral Compression Fracture Pain: A Case Report. 外周神经刺激治疗急性椎体压缩性骨折疼痛1例。
Pain medicine case reports Pub Date : 2025-04-01
Tony K George, Alfred J Tria
{"title":"Peripheral Nerve Stimulation for Acute Vertebral Compression Fracture Pain: A Case Report.","authors":"Tony K George, Alfred J Tria","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Vertebral compression fracture (VCF) pain can be debilitating, affecting daily activities and quality of life. This case presentation shows the utility of peripheral nerve stimulation (PNS) for acute pain relief in the setting of an acute VCF.</p><p><strong>Case report: </strong>This case is of an 84-year-old woman with osteoporosis and an acute T9 compression fracture reporting significant pain relief with 60-day PNS when medications and modalities failed to relieve pain. PNS is utilized for acute and chronic nerve pain with an expanding role for acute postoperative pain and chronic nociceptive, nociplastic, and neuropathic pain. This case report highlights the expanding role of PNS for managing acute pain.</p><p><strong>Conclusions: </strong>This novel approach to addressing acute insufficiency fracture pain highlights a promising alternative to inadequately relieved acute pain with conventional medication management or augmentation limitations due to patient comorbidities.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"127-130"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spinal Cord Stimulator Implantation in a Patient With Diffuse Idiopathic Skeletal Hyperostosis: Case Report. 脊髓刺激器植入治疗弥漫性特发性骨骼增生1例。
Pain medicine case reports Pub Date : 2025-04-01
Shabaaz M Baig, Adejuyigbe Adaralegbe, Sangel Gomez, Tabhata Paulet, Carol Apai, Mia Castiglione, Adejimi Adaralegbe, Akwasi Amponsah
{"title":"Spinal Cord Stimulator Implantation in a Patient With Diffuse Idiopathic Skeletal Hyperostosis: Case Report.","authors":"Shabaaz M Baig, Adejuyigbe Adaralegbe, Sangel Gomez, Tabhata Paulet, Carol Apai, Mia Castiglione, Adejimi Adaralegbe, Akwasi Amponsah","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Diffuse idiopathic skeletal hyperostosis (DISH) is a noninflammatory skeletal disorder causing calcifications and ossification of ligaments and tendons. We present a patient with undiagnosed DISH in whom a spinal cord stimulator (SCS) provided adequate pain relief while the disease progressed to become debilitating.</p><p><strong>Case report: </strong>The patient is a 66-year-old woman with an SCS placed for lower back pain due to degenerative changes. The patient presented to the emergency department with progressive right-sided lower extremity weakness and a 3-day history of urinary incontinence. Computed tomography showed new osteophytes consistent with DISH throughout the thoracic spine to the level of T10-T11.</p><p><strong>Conclusions: </strong>Our aim with this case report is to demonstrate the importance of preoperative imaging as well as follow-up imaging to evaluate the progression of DISH and having an extensive conversation with patients about whether an SCS is the right choice to manage their pain.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"85-87"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete, Sustained Resolution of Pain With Pseudoarthrectomy for Bertolotti Syndrome: A Case Report. 假关节切除术治疗Bertolotti综合征疼痛的完全、持续解决：1例报告。
Pain medicine case reports Pub Date : 2025-04-01
Emanuel Narcis Husu, Nirav Parekh, Jeremy I Simon
{"title":"Complete, Sustained Resolution of Pain With Pseudoarthrectomy for Bertolotti Syndrome: A Case Report.","authors":"Emanuel Narcis Husu, Nirav Parekh, Jeremy I Simon","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Bertolotti syndrome, characterized by lumbar pain due to a lumbosacral (LS) transitional vertebra, is a known but still controversial and overlooked pain generator despite an explosion of information on the condition in the last decade. Current management includes plain radiography, advanced imaging, minimally invasive interventions, and LS fusion.</p><p><strong>Case report: </strong>We present a unique case of a middle-aged man with Castellvi IIa Bertolotti syndrome consisting of a unilateral enlarged, dysplastic L5 transverse process forming a pseudoarticulation (PA) with the ilium and normal anatomy contralaterally. He was diagnosed on a plain radiograph and following a diagnostic injection of the PA, he received complete, sustained pain relief from a pseudoarthrectomy.</p><p><strong>Conclusions: </strong>This case illustrates an economical and thoughtful approach to diagnosis and management that may offer pain relief rather than invasive management with surgical fusion that comes with its own morbidity and mortality and consequences, such as adjacent-level disease.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"103-107"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of Intrathecal Drug Delivery System to Manage Refractory Abdominal Pain From Systemic Amyloidosis. 鞘内给药系统治疗系统性淀粉样变引起的难治性腹痛。
Pain medicine case reports Pub Date : 2025-04-01
Muhammad Shahzad, Somnath Bagchi, David Hutchins, Samiul Muquit
{"title":"The Use of Intrathecal Drug Delivery System to Manage Refractory Abdominal Pain From Systemic Amyloidosis.","authors":"Muhammad Shahzad, Somnath Bagchi, David Hutchins, Samiul Muquit","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Systemic amyloidosis can cause severe refractory pain, often inadequately managed with conventional analgesics. Intrathecal drug delivery systems (IDDS) have been used for chronic pain control but are rarely reported in amyloidosis cases.</p><p><strong>Case report: </strong>We present a female patient in her late 50s with systemic light-chain amyloidosis and type III intestinal failure, experiencing significant weight loss and debilitating abdominal pain during enteral and parenteral feeding. After unsuccessful trials of oral analgesics, antineuropathic medications, and interventional procedures, an IDDS was implanted to deliver a combination of bupivacaine and morphine. The therapy allowed her to resume enteral and parenteral nutrition, reduce opioid consumption, gain weight, improve functionality, and decrease hospital admissions despite disease progression.</p><p><strong>Conclusions: </strong>This case highlights the efficacy of intrathecal analgesia in managing severe refractory pain from amyloidosis. Early consideration of IDDS may improve quality of life in similar patients by providing effective long-term pain control.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"109-113"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Spinal Cord Injury After Uncomplicated Implantation of a Spinal Cord Stimulator: A Case Report. 脊髓刺激器植入后脊髓损伤1例报告。
Pain medicine case reports Pub Date : 2025-04-01
Jimmy Wen, Shannon Dwyer, Sugamjot Badhan, Ramy Khalil, Foad Elahi
{"title":"A Rare Case of Spinal Cord Injury After Uncomplicated Implantation of a Spinal Cord Stimulator: A Case Report.","authors":"Jimmy Wen, Shannon Dwyer, Sugamjot Badhan, Ramy Khalil, Foad Elahi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Spinal cord stimulation (SCS) is an efficacious, safe, and well-documented procedure for treating chronic refractory pain syndromes. We report a rare case of spinal cord injury (SCI) after SCS implantation in a 54-year-old woman.</p><p><strong>Case report: </strong>A 54-year-old woman underwent reimplantation of a new SCS following an acute L2 compression fracture that led to significant pain and dysesthesia. The intraoperative course was uncomplicated. Immediately postoperatively, the patient experienced an inability to move her right leg, with magnetic resonance imaging showing epidural fluid collections at the level of lead insertion; after subsequent removal of the SCS, the patient continued to experience paralysis in the right leg, with the development of painful neuropathy and allodynia. The patient was sent to acute rehabilitation, where her lower limb strength gradually improved, but has not returned to baseline.</p><p><strong>Conclusions: </strong>This case provides a useful clinical and procedural case on postoperative SCI after an uncomplicated SCS implantation.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"137-141"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Basivertebral Nerve Ablation in a Patient With Ankylosing Spondylitis: A Case Report. 强直性脊柱炎患者椎体神经消融1例报告。
Pain medicine case reports Pub Date : 2025-04-01
Abhinav Gupta, Edmund Posadas, Brooke Towne, Jeffrey Chen, Rajiv D Reddy
{"title":"Basivertebral Nerve Ablation in a Patient With Ankylosing Spondylitis: A Case Report.","authors":"Abhinav Gupta, Edmund Posadas, Brooke Towne, Jeffrey Chen, Rajiv D Reddy","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Lower back pain is a symptom of ankylosing spondylitis (AS), stemming from arthritic changes within the sacroiliac joints, lumbar facet joints, and between the vertebral bodies. Most commonly, interventional techniques targeting the sacroiliac or facet joints have been used to mitigate AS-related pain.</p><p><strong>Case report: </strong>In this case report, we describe a patient with AS and axial lower back pain who experienced insufficient and temporary relief with these first-line procedures. Furthermore, magnetic resonance imaging (MRI) showed degenerative changes to vertebral endplates suggesting a vertebrogenic cause for his pain. We proceeded with basivertebral nerve ablation for this patient, which resulted in superior and enduring pain relief.</p><p><strong>Conclusions: </strong>This is the first published report of basivertebral nerve ablation in a patient with AS that we know of. We demonstrate the potential for basivertebral nerve ablation to alleviate axial lower back pain for patients with AS who have vertebrogenic changes on MRI.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"89-92"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin Depigmentation After Particulate Steroid Injection for de Quervain's Tenosynovitis. 颗粒类固醇注射治疗de Quervain腱鞘炎后皮肤色素脱失。
Pain medicine case reports Pub Date : 2025-04-01
Simon Yang, Vinh Nguyen, Ratan K Banik
{"title":"Skin Depigmentation After Particulate Steroid Injection for de Quervain's Tenosynovitis.","authors":"Simon Yang, Vinh Nguyen, Ratan K Banik","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Corticosteroid injections are an effective treatment for several medical conditions, including de Quervain's tenosynovitis. Depigmentation of the skin after steroid injection is rarely reported.</p><p><strong>Case report: </strong>We present a case of a 43-year-old man who has no significant past medical history and came to us with an 8-week history of left wrist pain consistent with de Quervain's tenosynovitis. He underwent injections of triamcinolone and bupivacaine into the tendon sheath of the extensor pollicis brevis and abductor pollicis longus. Shortly after 3-5 days posttreatment, he had 100% pain relief, which continued for 12 months. However, one week after injection, he developed depigmentation at the injection site, measuring 2 cm x 3 cm. Depigmentation spontaneously resolved after 9 months.</p><p><strong>Discussion: </strong>The exact etiology of steroid-induced depigmentation is unknown, but it can have a profound impact on the patient. Interventional pain physicians should counsel patients about this adverse outcome and be aware of how to minimize its likelihood.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"143-146"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sacroiliac Joint Fusion Using the Silo TFX™ Transfixing Bridge Titanium Device: Two Case Reports from the United States. 使用Silo TFX™钛合金穿孔桥装置进行骶髂关节融合：来自美国的2例报告。
Pain medicine case reports Pub Date : 2025-04-01
Angela Nguyen, Macie Serio, Hirni Patel, Azem A Chami, Sahar Shekoohi, Alan D Kaye
{"title":"Sacroiliac Joint Fusion Using the Silo TFX™ Transfixing Bridge Titanium Device: Two Case Reports from the United States.","authors":"Angela Nguyen, Macie Serio, Hirni Patel, Azem A Chami, Sahar Shekoohi, Alan D Kaye","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Sacroiliac joint (SIJ) pain is a common source of chronic low back pain, accounting for 15% to 30% in patients without disc herniation or radicular pain. Multiple advances have been made in managing SIJ pain with the development of minimally invasive SIJ fusion devices. Minimally invasive SIJ fusion with a posterior approach has shown promising results in recent literature. One of the newly developed SIJ fusion devices utilizing a posterior approach is SiLO TFX™, Transfixing Bridge, a titanium device. The device uses a posterolateral approach with a single transfixing cone and ancillary ilium and sacrum screws. The case reports presented herein are the first cases of SIJ fusion performed with SiLO TFX™ Transfixing Bridge in the United States.</p><p><strong>Case report: </strong>Two patients with chronic bilateral sacroiliitis refractory to conservative management with greater than 75% short-term relief with sacroiliac injections, underwent SIJ fusion surgery with a novel transfixing bridge titanium device, the SiLO TFX™. Both patients showed resolution of the SIJ pain.</p><p><strong>Conclusion: </strong>These case reports discuss the unique aspects of the novel device, procedural steps, and early postoperative results, filling a gap in the current literature on titanium-based SIJ fusion.</p>","PeriodicalId":520525,"journal":{"name":"Pain medicine case reports","volume":"9 2","pages":"97-101"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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